• Title/Summary/Keyword: Acts

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Helicobacter pylori Chaperone-Like Protein CagT Plays an Essential Role in the Translocation of CagA into Host Cells

  • Ding, Honglei;Zeng, Hao;Huang, Linping;Dong, Yandong;Duan, Yijun;Mao, Xuhu;Guo, Gang;Zou, Quanming
    • Journal of Microbiology and Biotechnology
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    • v.22 no.10
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    • pp.1343-1349
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    • 2012
  • Most of the Helicobacter pylori strains containing the cag pathogenicity island (PAI) have been associated with more severe gastric disease in infected humans. The cag PAI is composed of 27 proteins, and some of the components are required for CagA translocation into host cells as well as induction of proinflammatory cytokines, such as interleukin-8 (IL-8); however, the exact function of most of the components remains unknown or poorly characterized. In this study, we demonstrated that CagT (HP0532), which is an essential structural component of the cag PAI apparatus, plays an important role in the translocation of CagA into host epithelial cells. In addition to being located on the bacterial surface, CagT is also partially localized in the inner membrane, where it acts as a chaperone-like protein and promotes CagA translocation. However, CagT secretion was not detected by immunoprecipitation analysis of cell culture supernatants. Meanwhile, CagT was related to the introduction of IL-8 of the host cell. These results suggest that CagT is expressed on both the inner and outer bacterial membranes, where it serves as a unique type IV secretion system component that is involved in CagA secretion and cag PAI apparatus assembly.

A Study on Occurance Possibility of Suicide Bombing using Utilize Unmanned Aircraft in Korea (한국 내 무인항공기를 이용한 자폭테러 발생가능성에 대한 연구)

  • Oh, Seiyouen;Lee, Jaemin;Park, Namkwun
    • Journal of the Society of Disaster Information
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    • v.10 no.2
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    • pp.288-293
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    • 2014
  • The purpose of this study was to provide response plans against acts of suicide bomb using utilize unmanned aircrafts to prevent large losses of lives such as the terrorist attacks of September 11. As the result, First, this research suggests revising the definition and categorization of utilizing unmanned aircrafts and legislating the Anti-terrorism law. Second, it is needed to establish the proper social safety network through terrorism response management integrated system against the terror of related organization. Third, suicide bomb using utilizing unmanned aircrafts can be occurred because it is possible to make bomb and open web site for terrorism without connection with terrorist organization because of universal use of Internet. In response to this, it is needed to make a law which can block the use and open of illegal site and contents. Forth, the increasing number of foreigners and immigrants can make conflicts, and cause the foreigner's anti-korea feeling and the citizen's anti-cultural diffusion. Therefore, it is needed for the citizen to change and improve the awareness of them, and the change of social politics.

A Study on the Character of Interior Design of Modern Church - Focused on the Chancel of the Presbyterian Church in Korea - (현대 교회건축 인테리어 디자인 특성에 관한 연구 - 국내 개신교회 강단을 중심으로 -)

  • Lee, Gyoo-Baek
    • Archives of design research
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    • v.19 no.2 s.64
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    • pp.173-182
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    • 2006
  • In church building, the worship space performing practical rituals and making a place of friendship and education has a role to accept the changing services with the times. And it is also distinguishable from the chaotic surroundings and is the space for religious experience of christian identity we cannot experience in our daily life. Therefore it is very important to investigate its characteristic as the space for religious experience. The important purpose of church building is to make up a worship space, and the chancel in worship space is said to be the core in church building, the center of all worship acts. Especially, today with the tendency of multi-functionalizing and opening in worship space, the chancel in worship space has a more special meaning as spatial, functional and symbolic center. The purpose of this study, with the worship space in domestic protestant churches, is to make up basic data for the worship space plan and interiordesign in church building by analyzing the characteristics of interior design for chancel, the core field of worship space. This study has researched the constituentcharacteristics of interior design for the chancel in worship space in domestic protestant churches in 10 years from 1995 to 2004. And found the worship space opening and multi-functionalizing with the changing times. From now on, the study on interior design for creative worship space should be researched positively for the purpose of expressing the christian identity and the opening and muti-functions, on the basis of christian theology.

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Impact of Largemouth Bass (Micropterus salmoides) on the Population of Korean Native Fish, Crucian Carp (Carassius auratus) (배스가 국내 호소에 서식하는 붕어 개체군에 미치는 영향)

  • Lee, Jin-Woong;Kim, Jeong-Hui;Park, Sang-Hyeon;Choi, Kee-Ryong;Lee, Hae-Jin;Yoon, Ju-Duk;Jang, Min-Ho
    • Korean Journal of Environmental Biology
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    • v.31 no.4
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    • pp.370-375
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    • 2013
  • Exotic species in aquatic ecosystem generate various problems domestically as well as globally. Largemouth bass (Micropterus salmoides) which is a well-known exotic species globally, acts as a substantial disturbance factor on the native fish communities in Korea due to the high predation pressure and hence designated as a ecologically harmful species by Ministry of Environment. In this study, we investigated the impact of largemouth bass on Korean native fish population, crucian carp (Carassius auratus), to identify responses of the prey fish. Two fish species were collected at seven reservoirs distributed at the Nakdong River catchment area, and changes in length-frequency and length-weight relationship (LWR) were analysed depending on existence of large-mouth bass. At bass absent sites, ratio of under age 1 year individuals were small, and over age two years were dominant. Conversely, normal length-frequency distribution pattern was identified at bass absent sites. The LWR of crucian carp (fish smaller than total length of 160 mm were only considered as it is frequently consumed by bass predation) was different depending upon bass existence. The value of parameter b at bass absent reservoirs was 2.909, which was smaller than that of bass present reservoirs, 3.100. Our results imply that crucian carp at bass present reservoirs presented a different strategy to survive from predation by bass, through relatively rapid growth. We propose that other native species might have similar growth strategies like crucian carp.

Weed control efficacy of the tank-mixture between quizalofop-P-ethyl and KSC-35089, a newly synthesized N-arylphthalimide compound (신규합성된 N-arylphthalimide 화합물 KSC-35089와 Quizalofop-ethyl의 혼합처리효과)

  • Kim, Tae-Joon;Song, Jae-Eun;Choi, Jung-Sup;Kim, Hyoung-Rae;Pyon, Jong-Young;Cho, Kwang-Yun
    • The Korean Journal of Pesticide Science
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    • v.6 no.3
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    • pp.183-192
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    • 2002
  • Herbicidal effect of KSC-35089, a newly synthesized N-arylphthalimide compound, was examined, and its interaction with quizalofop-P-ethyl when foliar applied as a tank-mixture was evaluated under a greenhouse condition. KSC-35089 showed stronger herbicidal activity on broadleaves than grasses, suggesting that it would be an appropriate partner for non-selective weed control with quizalofop-P-ethyl, a strong grasskilling ageant. In general, the interaction between KSC-35089 and quizalofop-P-ethyl appeared to be additive, which indicates each compound acts on whole plant level independently. This additive interaction was confirmed in a spectrum test using 19 grasses and 26 broadleaves. Under the greenhouse condition, all tested plants were controlled around 90% level through a foliar application with a tank-mixture of KSC-35089 at 64 g ai/ha and quizalofop-P-ethyl at 32 g ai/ha. Further study would be required on the action mechanism of this additive interaction.

Production of ${\beta}-Galactosidase$ with High Transgalactosylation Activity by Bacillus sp. A4442 Mutant (변이주 Bacillus sp. A4442에 의한 갈락토스 전이활성이 높은 ${\beta}-Galactosidase$의 생산)

  • Choi, Kyung-Ho;Yang, Sung-Joon;Kim, Min-Hong;Han, Keum-Soo;Yang, Ji-Won;Jung, Jin;In, Man-Jin
    • Applied Biological Chemistry
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    • v.38 no.6
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    • pp.507-511
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    • 1995
  • In an attempt to improve the productivity of ${\beta}-galactosidase$ from Bacillus sp. A1, which was isolated from soil and has remarkably higher transgalactosylation activity than lactose hydrolysis activity, a chemical mutation procedure using N-methyl-N'-nitro-N-nitrosoguanidine followed by selection was conducted. The final selection, designated as Bacillus sp. A4442, turned out to show a substantially increased enzyme productivity. Catabolite repression by glucose and lactose requirement as an inducer for the enzyme biosynthesis, which were shown in the parent strain, was markedly diminished; instead it was found out that galactose acts as another inducer. Because pH of medium, one of the most important factors for cell growth as well as enzyme production, is closely related with the sugar concentration during culture, it was kept in the optimum range of $6.5{\sim}7.5$; for this the initial glucose concentration was adjusted to be 0.5% which was thereafter maintained by the controlled pumping-in of lactose using the pH-stat technique. By doing so, we were able to increase the productivity of ${\beta}-galactosidase$ with high transgalactosylation activity up to $44\;unit/m{\ell}-broth$.

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An Experimental Study for Longitudinal Resistance of Ballast Track on Bridge (교량 상 자갈궤도의 종저항력 측정을 위한 실험 연구)

  • Min, Kyung-Hwan;Yun, Kyung-Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.5
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    • pp.173-178
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    • 2016
  • When a ballast track of a high-speed train is constructed on a bridge, the displacement of the bridge decks can occur because they are not fixed to the rails. Moreover, relative displacements occur between the bridge and rails caused by temperature changes and external loads. The current longitudinal resistance criteria (UIC Code 774-3, KR C-08080) on ballast tracks with continuous welded rails (CWRs) do not take into account the longitudinal movement of the bridge and the frictional force between the ballast and slabs. In addition, the magnitude of the longitudinal resistance, k, is calculated somewhat conservatively and, (therefore?) it acts as an unfavorable element in the design of long span and continuous railway bridges. Thus, in order to replicate the actual behavior more effectively, the longitudinal resistance of CWRs should take into account the additional rigidity between the slab and track. In this study, the longitudinal resistances of the ballasted track on the bridge were analyzed by carrying out an experimental study with a test setup designed to simulate the deck and bed track. In the test results, the maximum longitudinal resistances of the tests were similar to the resistances of the current codes, however, the measured longitudinal stiffness designed to limit the displacement of the tests were much smaller in comparison with the longitudinal stiffness on the codes.

Implementation of Video-Forensic System for Extraction of Violent Scene in Elevator (엘리베이터 내의 폭행 추출을 위한 영상포렌식 시스템 구현)

  • Shin, Kwang-Seong;Shin, Seong-Yoon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.18 no.10
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    • pp.2427-2432
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    • 2014
  • Color-$X^2$ is used as a method for scene change detection. It extracts a violent scene in an elevator and then could be used for real-time surveillance of criminal acts. The scene could be also used to secure after-discovered evidences and to prove analysis processes. Video Forensic is defined as a research on various methods to efficiently analyze evidences upon crime-related visual images in the field of digital forensic. The method to use differences of color-histogram detects the difference values of histogram for RGB color from two frames respectively. Our paper uses Color-$X^2$ histogram that is composed of merits of color histogram and ones of $X^2$ histogram, in order to efficiently extract violent scenes in elevator. Also, we use a threshold so as to find out key frame, by use of existing Color-$X^2$ histogram. To increase the probability that discerns whether a real violent scene or not, we take advantage of statistical judgments with 20 sample visual images.

UbiCore : An Effective XML-based RFID Middleware System (UbiCore : XML 기반 RFID 미들웨어 시스템)

  • Lee, Hun-Soon;Choi, Hyun-Hwa;Kim, Byoung-Seob;Lee, Myung-Cheol;Park, Jae-Hong;Lee, Mi-Young;Kim, Myung-Joon;Jin, Sung-Il
    • Journal of KIISE:Databases
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    • v.33 no.6
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    • pp.578-589
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    • 2006
  • Owing to the proliferation of Radio Frequency Identification (RFID) technologies which is being watched as a core technology of ubiquitous computing, applications which offer convenience to people using RFID technologies are more and more increased. To easily develop these applications, a middleware system which acts as a bridge between RFID hardware and application is essential. In this paper, we propose a novel XML-based RFID middleware system called UbiCore (Ubiquitous Core). UbiCore has following features: First, UbiCore employs its own query language called XQueryStream (XQuery for Stream Data) which is originated from XQuery. Second, UbiCore has the preprocessing phase called pre-filtering prior to query evaluation and reuses the intermediate result of previous evaluation to speed up the processing of RFID tag data stream. Third, UbiCore supports query on both continuously generated stream data and archived historical data. And last, UbiCore offers a distinct markup language called Context-driven Service Markup Language (CSML) to easily specify the linking information between context and service.

Leaching of Valuable Metals from NCM Cathode Active Materials in Spent Lithium-Ion Battery by Malic acid (폐리튬이온전지 NCM 양극활물질로부터 말릭산을 이용한 유가금속의 침출)

  • Son, Seong Ho;Kim, Jin Hwa;Kim, Hyun-Jong;Kim, Sun Jung;Lee, Man Seung
    • Resources Recycling
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    • v.23 no.4
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    • pp.21-29
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    • 2014
  • Nickel, cobalt and manganese-based(NCM, $Li(Ni_xCo_yMn_z)O_2$) cathode active materials of spent lithium-ion batteries contained valuable metals such as cobalt(15 ~ 20%), nickel(25 ~ 30%), manganese(10 ~ 15%) and lithium(5 ~ 10%). It was investigated the eco-friendly leaching process for the recovery of valuable metal from spent lithium-ion battery NCM cathode active materials by DL-malic acid($C_4H_5O_6$) as an organic leachant in this research. The experiments were carried out to optimize the process parameters for the recovery of cobalt, nickel and lithium by varying the concentration of lixivant, reductant concentration, solid/liquid ratio and temperature. The leaching solution was analyzed using ICP-OES(Inductively Coupled Plasma Optic Emission Spectrometer). Cathode active materials of 5 wt. % were introduced into the leaching solution which was 2 M DL-malic acid in addition of 5 vol. % $H_2O_2$ at $80^{\circ}C$ and it resulted in the recovery of 99.10% cobalt, 99.80% nickel and 99.75% lithium in 120 min. $H_2O_2$ in DL-malic acid solution acts as an effective reducing agents, which enhance the leaching of metals.