• 한국주조공학회지
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• 제25권4호
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• pp.161-167
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• 2005

The experiment of hot dip interaction tests was carried out in order to study the formation behavior of interfacial reaction layer between as-received STD61 hot work tool steel and a commercial pure aluminum melt, Al-xwt.%Fe(x=0.2, 0.5, 0.8 and 1.1) alloys melt and Al-xwt.%Si(x=1.0, 4.0, 7.0 and 10.0) alloys melt, respectively. The results show that the reaction layer, over 300 ${\mu}m$ in thickness, is easily formed by the dissolution of silicon from as-received tool steel. When the iron content in the aluminum alloy is higher than 1.1 wt.%, the thickness of reaction layer decreases below 180 ${\mu}m$ by preventing iron dissolution from the tool steel. The silicon dissolved from tool steel acts as a strong promoter on the formation of reaction layer, but the alloyed silicon in molten aluminum alloys acts as an inhibitor on the formation of reaction layer.

• 전기학회논문지
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• 제57권3호
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• pp.390-397
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• 2008

Permanent Magnet Linear Synchronous Motor (PMLSM) has high efficiency, high energy density, and high control-ability. But, the detent force always is produced by the structure of slot-teeth. There are the disadvantages such as noise and vibration of the apparatuses are induced and the control ability is curtailed because detent force acts as thrust ripple. Therefore, the detent force reduction is an essential requirement in PMLSM. Generally, the method, skewing permanent magnet or slot-teeth, is used to reduce the detent force. But the thrust is decreased at the same time. If permanent magnet is skewed, the lateral force which operates as the perpendicular direction of skew direction is generated in linear guide of PMLSM. So, V-skew model is proposed for the reduction of lateral force. The lateral force acts as braking force in linear motion guide, and it has bad influence to the characteristics of PMLSM. However, these problems will not be solved by 2-dimensional Finite Element Analysis (FEA). So, in this paper 3-dimensional FEA is applied to analyze the PMLSM where permanent magnet is skewed and has overhang. The detent force and thrust characteristics considering skew and overhang effects of permanent magnet are analyzed by 3-dimensional FEA and the results are compared with experimental values to verify the propriety of analysis.

• 대한가정학회지
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• 제35권6호
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• pp.191-203
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• 1997

This paper is study the ways of finding sexual abuse facts of children at home and the standards of recognizing such facts. The investigation and recognition about sexual abuse of children are necessary for remedy or care of children and their family and also for punishment upon the harmer or sanction against him by family laws. But, on account of the characteristics of sexual abuse acts and the standpoint that sufferers are children, it's very difficult to find those kinds of facts. Medical examinations, observations by specialists behavioral indicators, use of dolls & other props, and interviewing are applied to finding sexual abuse facts of children. However, these investigating methods have many uppermost limits, and don't necessarily have conformable conclusions. especially 'interviewing' is essentially used to find a child who has suffered sexual abuses and to investigate and examine a harmer who has been charged with such sexual acts. but 'interviewing' has no less obstacles in reality than has some utilities. For that reason, a follow-up study of (what is) the most effective method is required, with the case=by-case application of other methods. And along with that, it must be taken into consideration that, in process of finding a sexually abused child and in ex post facto measure against accompanying ill effects, the child's protection and the family's privacy ought to be legally guaranteed. So to speak, in making and enforcing the family laws, a profound study of the family to produce good fruits must be made.

• BMB Reports
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• 제45권9호
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• pp.526-531
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• 2012

Many malignant tumors become resistant to tumor necrosis factor-alpha (TNF-${\alpha}$)-induced cell death during carcinogenesis. In the present study, we examined whether parkin acts as a tumor suppressor in HeLa cells, a human cervical cancer cell line resistant to TNF-${\alpha}$-induced cell death. TNF-${\alpha}$-treatment alone did not affect HeLa cell viability. However, expression of parkin restored TNF-${\alpha}$-induced apoptosis in HeLa cells. Increased cell death was due to the activation of the apoptotic pathway. Expression of parkin in TNF-${\alpha}$-treated HeLa cells stimulated cleavage of the pro-apoptotic proteins caspase-8, -9, -3, -7 and poly ADP ribose polymerase (PARP). In addition, parkin expression resulted in decreased expression of the caspase inhibitory protein, survivin. These results suggest that parkin acts as a tumor suppressor in human cervical cancer cells by modulating survivin expression and caspase activity. We propose that this pathway is a novel molecular mechanism by which parkin functions as a tumor suppressor.

• Journal of Mechanical Science and Technology
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• 제14권8호
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• pp.867-878
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• 2000

In order to study unsteady aerodynamic loads on high speed trains passing by each other 350km/h, three-dimensional flow fields around trains during the crossing event are numerically simulated using three-dimensional Euler equations. Roe's FDS with MUSCL interpolation is employed to simulate wave phenomena. An efficient moving grid system based on domain decomposition techniques is developed to analyze the unsteady flow field induced by the restricted motion of a train on a rail. Numerical simulations of the trains passing by on the double-track are carried out to study the effect of the train nose-shape, length and the existence of a tunnel on the crossing event. Unsteady aerodynamic loads-a side force and a drag force-acting on the train during the crossing are numerically predicted and analyzed. The side force mainly depends on the nose-shape, and the drag force depends on tunnel existence. Also. a push-pull (i.e.impluse force) force successively acts on each car and acts in different directions between the neighborhood cars. The maximum change of the impulsive force reaches about 3 tons. These aerodynamic force data are absolutely necessary to evaluate the stability of high speed multi-car trains. The results also indicate the effectiveness of the present numerical method for simulating the unsteady flow fields induced by bodies in relative motion.

• BMB Reports
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• 제34권2호
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• pp.139-143
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• 2001

Thioredoxin (Trx) is a redox protein possessing conserved sequence Cys-Gly-Pro-Cys in ail organisms. Trx acts as an electron donor of many proteins including thioredoxin peroxidase (TPx). Yeast Trx 2 has two redox active cysteine residues at positions 31 and 34. To investigate the redox activity of each cysteine, we generated mutants C31S, C34S, and C31S/C34S using site directed mutagenesis and examined the redox activity of Trx variants as an electron donor for yeast TPx enzymes. None of the three Cysmutated Trx proteins was active as a redox protein in the 5', 5'-dithiobis-(2-dinitrobenzoic acid) reduction under the condition of the presence of NADPH and thioredoxin reductase, and in the thioredoxin dependent peroxidase activity of yeast TPx II. C34S enhanced the glutamine synthetase protection activity of yeast TPx I, even though 100 times more protein was needed to exhibit the same activity to WT. The formation of a mixed disulfide intermediate between Trx and TPx II subunits was analyzed by SDS-PAGE. The mixed dieter form of TPx II was found only for C34S. These results suggest that Cys-31 more effectively acts as an electron donor for TPx enzymes.

• 한국전자거래학회지
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• 제1권1호
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• pp.5-26
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• 1996

This paper aims to present a prospective trend to establish a proper CALS conception and an efficient CALS environment in Korea.. It is crucial at this point for Korea to develop a comprehensive CALS conception which considers our present economic and social situation, national security, and our national emotion. Korean CALS has been developed and led mainly by the government and private industry. It is now necessary to improve CALS conception in Korea by making CALS standard more interchangeable among international as well as domestic business fields through EDI and the automation of the industries along with the government. In this regard, this paper proposes three potential methods to accomplish this goal and discuss each of them in detail. First, we suggest to establish a proper CALS introduction policy on the government level. We propose an introduction policy with three phases such as introduction, spreading and target which will cover through the year 1996 to 2007. Second. we suggest to establish a proper CALS standardization policy by improving the acquisition of digital data and process, and modernizing infrastructure. Third, we suggest that the government should amend and enforce the necessary laws and acts for more efficient CALS implementation in Korea. Government should arrange for these acts to be applied not optionally but obligatorily to Korean enterprises so that they survive the harsh and competitive world market in the upcoming 21th century.

• 한국실내디자인학회논문집
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• 제13권3호
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• pp.93-103
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• 2004

This thesis aims to show the design logics and the meta-design of a public restroom "Between You and Me." This work reinterprets a public restroom regarded as the typical public space by means of spatial agency's influences, on the assumption thor spatial agency controls the properties of public space. This thesis examines our representational system against the public space, and our specific experience in it with the conceptual model of meta-design. Meta-design is a design beyond the design usually we think of. Experiential meta-design, "Between You and Me" presented as the object of this thesis, is a constructive design project which converts our negative perception of the restroom to a new one, "interface." This project, composed of the surrealistic spatial arrangement, urges us to reconsider our fixed thoughts of the restroom and try a creative experience in it. Finally this thesis shows how the space's way of existence fixes our acts and thoughts, and what enables the repetitive acts and thoughts often emerged In our relations with the public space through a meta-design.c space through a meta-design.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제12권2호
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• pp.69-77
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• 2006

Angiography means that a check up to know an abnormal condition in all the blood vessels include from the heart, aortae, cerobrovascular and abdonominal artery to hands and feet. Main examples of this are cerebral angiography, abdominal, liver for urinary anomaly, renovascular angiography, and artery and vein in arms and legs. Angiography uses radial rays or angiography equipment for an image output during interventional procedure and compositive diagnosis. The acts which performed in a projection room have changed drastically. In general, it is performed by using equipment which is attached one or two C-arms and the method of inserting catheter in vein after anesthesia. For this reason, some rooms that consist of angiography room units should be planned not only for expensiveness equipment and facilities also to be germ-free. Nowadays, in the angiography unit case, it is placed independently as the central part of many hospitals. It does not belong to the imaging medical department any more as considering raising filming times and the relation between C.C.U.(coronary care unit) and operation unit. This means the acts performed are diversified and well-organized rooms in support of diagnosis are required. However, it is difficult to plan the angiography room unit due to domestic researches and data on this unit are not enough. Therefore, this study aims at bringing up basic issue for architectural planning of the angiography unit in general hospital.

• 한국정보전자통신기술학회논문지
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• 제3권1호
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• pp.24-30
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• 2010

본 논문에서는 전기적 소형 모노폴 형태의 안테나가 제시되었다. 크기가 매우 짧은 (${\iota}{\approx}{\lambda}_g/15$ ) 모노폴은 용량성 소자로 동작하며, 접지면 위에 놓여진 개방형 슬롯구조는 유도성 소자로 동작하므로, 이 들 두 소자를 결합시킨 구조는 LC 공진기를 형성하게 된다. 안테나에 대한 등가회로 모델 은 안테나의 해석 및 설계의 정확성을 파악하기 위하여 사용되었다. 제안된 안테나는 매우 작은 전기적인 크기를 갖고 있으나 양호한 성능을 나타내고 있다. 측정된 안테나의 최대 이득과 효율은 주파수 2.1 GHz에서 각각 3.6 dBi 및 77.8 %를 나타내었다.