• Title/Summary/Keyword: Activity system

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Antimicrobial Activity of Areca catachu L. Extract of against Intestinal Pathogens (장내 유해세균에 대한 빈랑 추출물의 항균 활성)

  • 이갑상;김성효;전승호;박성수;박정순;신용서
    • The Korean Journal of Food And Nutrition
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    • v.11 no.1
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    • pp.36-40
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    • 1998
  • Areca catachu L. which was showed antimicrobial activity against intestinal pathogens through screening herbs related treatments of intestinal diseases, were extracted by methanol and fractionated by n-hexane, ethylether, ethylacetate, and water. Antimicrobial activities of the methanol extract and each fractionates were then investigated under the anaerobic broth system. All fractions of Areca catachu L. except of n-hexane showed antimicrobial activity against all tested pathogens. Especially, ethylacetate fraction of them had the most significant inhibition activity. There is no significant difference of antimicrobial activity among each fractionates. Fraction of Areca catachu L. ethylacetate fractionate, which were fractionated by Sephadex G-200 and Silica gel column chromatography revealed the strongest antimicrobial activity at 5 to 7 and 20 of fraction number, respectively.

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Effect of Sam Hwa San on Na-K-ATPase Activity in Microsomal Fraction of Rabbit Cerebral Cortex (삼화산(三和散)이 대뇌피질(大腦皮質) microsome분획(分劃)에서 Na-K-ATPase활성(活性)에 미치는 영향(影響))

  • Kim, Gil-Seop;Jeong, Ji-Cheon
    • The Journal of Korean Medicine
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    • v.16 no.1 s.29
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    • pp.281-294
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    • 1995
  • The effect of Sam Hwa San on the Na-K-ATPase activity was evaluated in microsomal fraction prepared from rabbit cerebral cortex to determine whether Sam Hwa San affects Na-K-ATPase activity of nervous system. Sam Hwa San markedly inhibited the Na-K-ATPase activity in a dose-dependent manner with an estimated $I_{50}$ of 0.12%. Optimal pH for the Na-K-ATPase activity was at 7.5 in the presence or absence of Sam Hwa San. The degree of inhibition by the drug more increased at acidic and alkalic pHs than neutral pH. Kinetic studies of substrate and cationic activation of the enzyme indicate classic noncompetitive inhibition fashion for ATP, Na and K, showing significant reduction in Vmax without a change in Km. Dithiothreitol, a sulfhydryl reducing reagent, partially protects the inhibition of Na-K-ATPase activity by Sam Hwa San. Combination of Sam Hwa San and ouabain showed higher inhibition than cumulative inhibition. These results suggest that Sam Hwa San inhibits Na-K-ATPase activity in central nervous system by reacting with, at least a part, sulfhydryl group and ouabain binding site of the enzyme protein, but with different binding site from those of ATP, Na and K.

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Intelligent Healthcare Service Provisioning Using Ontology with Low-Level Sensory Data

  • Khattak, Asad Masood;Pervez, Zeeshan;Lee, Sung-Young;Lee, Young-Koo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.5 no.11
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    • pp.2016-2034
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    • 2011
  • Ubiquitous Healthcare (u-Healthcare) is the intelligent delivery of healthcare services to users anytime and anywhere. To provide robust healthcare services, recognition of patient daily life activities is required. Context information in combination with user real-time daily life activities can help in the provision of more personalized services, service suggestions, and changes in system behavior based on user profile for better healthcare services. In this paper, we focus on the intelligent manipulation of activities using the Context-aware Activity Manipulation Engine (CAME) core of the Human Activity Recognition Engine (HARE). The activities are recognized using video-based, wearable sensor-based, and location-based activity recognition engines. An ontology-based activity fusion with subject profile information for personalized system response is achieved. CAME receives real-time low level activities and infers higher level activities, situation analysis, personalized service suggestions, and makes appropriate decisions. A two-phase filtering technique is applied for intelligent processing of information (represented in ontology) and making appropriate decisions based on rules (incorporating expert knowledge). The experimental results for intelligent processing of activity information showed relatively better accuracy. Moreover, CAME is extended with activity filters and T-Box inference that resulted in better accuracy and response time in comparison to initial results of CAME.

Central nervous system activity of the methanol extracts of Caesalpinia bonducella and Bauhinia racemosa (Caesalpinaceae) in experimental animal model

  • Kumar Ramanathan Sambath;Sivakumar Thangavel;Sundaram Rajagopal Shanmuga;Gomathi Periyasamy;Kumar Mani Senthil;Mazumdar Upal Kanti;Gupta Malaya
    • Advances in Traditional Medicine
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    • v.6 no.3
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    • pp.221-231
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    • 2006
  • The aim of the present study is to investigate central nervous system (CNS) activity of the methanol extracts of leaves of Caesalpinia bonducella (MECB) and stem bark of Bauhinia racemosa (MEBR) (Caesalpinaceae) in Swiss albino mice and Wistar albino rats. General behavior, exploratory behavior, muscle relaxant activity and phenobarbitone sodium-induced sleeping time were studied. The results revealed that the methanol extracts of leaves of Caesalpinia bonducella at 100 - 200 mg/kg and stem bark of Bauhinia racemosa 100 - 200 mg/kg caused a significant reduction in the spontaneous activity (general behavioral profile), remarkable decrease in exploratory behavioral pattern (Y-maze and head dip test), a reduction in muscle relaxant activity (rotarod and traction tests), and also significantly potentiated phenobarbitone sodium-induced sleeping time. The results suggest that MECB and MEBR exhibit CNS depressant activity in tested animal models.

The Association between Safety Care Activity and Documentation of Nursing Records among Nurses in General Hospitals (병원간호사의 안전간호활동과 간호기록 수행간의 관계)

  • Kang, Haeng Seon;Song, Hyo Jeong
    • Journal of Korean Critical Care Nursing
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    • v.11 no.3
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    • pp.85-94
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    • 2018
  • Purpose : The purpose of this study was to identify the association between safety care activity and documentation of nursing records among nurses working in hospitals and to provide basic data for developing hospital policy for the documentation of nursing records. Methods : By using a self-reported questionnaire, data were collected from 212 nurses working in six general hospitals in Jeju province from November 2015. Data were analyzed using descriptive statistics, t-test, ANOVA, Pearson correlation coefficients, and stepwise multiple regression with the SAS WIN 9.2 program. Results : Safety care activity was positively correlated with the documentation of nursing records (r=.83, p<.001). The documentation of nursing records was significantly predicted by safety care activity, working department, and nursing delivery system, and 70.9% of the variance in the documentation of nursing records was explained (F=172.31, p<.001). Conclusions : In this study, safety care activity was the most influencing factor for the documentation of nursing records. Improving work circumstances and building a system are required for nurses' safety care activity to lead to good documentation of nursing records.

Predictors Related to Activity Performance of School Function Assessment in School-aged Children with Spastic Cerebral Palsy (경직성 뇌성마비가 있는 학령기 아동의 학교기반 신체 활동수행력에 영향을 주는 요인)

  • Kim, Won-Ho
    • Journal of the Korean Society of Physical Medicine
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    • v.14 no.2
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    • pp.97-105
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    • 2019
  • PURPOSE: This study examined the factors related to school-based activity performance in school-aged children with spastic cerebral palsy (CP). METHODS: The Gross Motor Function Systems (GMFCS), Manual Ability Classification System (MACS), Communication Function Classification System (CFCS) as functional classifications, and the physical activity performance of the School Function Assessment (SFA) were measured in 79 children with spastic CP to assess the student's performance of specific school-related functional activities. RESULTS: All the function classification systems were correlated significantly with the physical activity performance of the SFA ($r_s=-.47$ to -.80) (p<.05). The MACS (${\beta}=-.59$), GMFCS (${\beta}=-.23$), CFCS (${\beta}=-.21$), and age (${\beta}=-.15$) in order were predictors of the physical activity performance of the SFA (84.8%)(p<.05). CONCLUSION: These functional classification systems can be used to predict the school-based activity performance in school-aged children with CP. In addition, they can contribute to the selection of areas for intensive interventions to improve the school-based activity performance.

The Analysis of the Activity Patterns of Dog with Wearable Sensors Using Machine Learning

  • Hussain, Ali;Ali, Sikandar;Kim, Hee-Cheol
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.05a
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    • pp.141-143
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    • 2021
  • The Activity patterns of animal species are difficult to access and the behavior of freely moving individuals can not be assessed by direct observation. As it has become large challenge to understand the activity pattern of animals such as dogs, and cats etc. One approach for monitoring these behaviors is the continuous collection of data by human observers. Therefore, in this study we assess the activity patterns of dog using the wearable sensors data such as accelerometer and gyroscope. A wearable, sensor -based system is suitable for such ends, and it will be able to monitor the dogs in real-time. The basic purpose of this study was to develop a system that can detect the activities based on the accelerometer and gyroscope signals. Therefore, we purpose a method which is based on the data collected from 10 dogs, including different nine breeds of different sizes and ages, and both genders. We applied six different state-of-the-art classifiers such as Random forests (RF), Support vector machine (SVM), Gradient boosting machine (GBM), XGBoost, k-nearest neighbors (KNN), and Decision tree classifier, respectively. The Random Forest showed a good classification result. We achieved an accuracy 86.73% while the detecting the activity.

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Bile Salt-Tolerance of Lactic Acid Bacteria under Anaerobic Broth System (혐기적 Broth System에서 젖산균의 담즙산염 내성)

  • 신용서;김성효;이갑상
    • Microbiology and Biotechnology Letters
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    • v.23 no.5
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    • pp.513-518
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    • 1995
  • To evaluate bile salt-tolerance of lactic acid bacteria (LAB, Lactobacillus acidophilus ATCC 4356, Lactobacillus casei IFO 3533, Streptococcus thermnophilus KCTC 2185, Lactobacillus lactis ATCC 4797, and Lactobacillus bulgaricus ATCC 11842), We investigated the survivals, acid production and $\beta $-galactosidase activity of LAB under anaerobic broth system. Cellular permeability of LAB and their cellular retention of $\beta $-galactosidase were also examined in the same system. Although the growth of LAB was slightly suppressed by 0.3% bile salt, they showed normal growth curve. Streptococcus thermophilus KCTC 2185 was significantly more resistant to bile salt than the others. The $\beta $-galactosidase activity from Streptococcus thermophilus KCTC 2185 and Lactobacillus bulgaricus ATCC 11842 and their cellular retention of $\beta $-galactosidase decreased by 0.3% bile salt. The cellular permeability of LAB in the presence of bile salt increased significantly.

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Studies on the Biologic Activities of the Constituents of Ailanthi Cortex Radicis(I) -Effects of Methanol Extract and its Chloroform Fraction on Epoxide Hydrolyzing System in Liver- (저근백피(樗根白皮) 성분(成分)의 생리생활(生理生活)에 관한 연구(硏究)(I) -메탄올 추출물과 클로로포름 분획이 Epoxide 분해계에 미치는 영향-)

  • Kim, Jong;Choi, Jong-Won;Kim, Hye-Kyung;Park, Soo-Wan;Lee, Chung-Kyu
    • Korean Journal of Pharmacognosy
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    • v.25 no.1
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    • pp.47-50
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    • 1994
  • For the biological survey, effects of Ailanthi Cortex Radicis, the root bark of Ailanthus altissima(Simaroubaceae) on epoxide hydrolyzing enzymes were checked. The methanolic extract and its chloroform fraction were shown to activate the liver metabolizing enzyme system including epoxide hydrolase system which was monitored by activities of transaminase, lactate dehydrogenase, alkaline phosphatase and epoxide hydrolase system in bromobenzene treated rats. But they showed no effect on glutathione S-transferase activity.

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A Study on the New Threat Level Decision Method for Information System (새로운 정보시스템 위협수준결정방법론에 대한 연구)

  • Kim, Tai-Hoon;Yeo, Sang-Soo;Cho, Sung-Eon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.12
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    • pp.2280-2286
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    • 2007
  • Information system contains various components, and these components can be categorized into some types. When preparing security level management activity, it is most important to define the target of management activity. And after deciding these targets, security level management activity can be started. This paper defines management targets by dividing information system into some parts, and shows these targets can be managed variously according to operation environments and characteristics.