• East Asian mathematical journal
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• 제28권2호
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• pp.173-195
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• 2012

The purpose of this study is to help for an in-depth understanding of their thinking process by observing and analyzing the response found by two elementary school students, Through this study, the following findings could be obtained. First, two students have a tendency trying to solve the complex situation at first. Second, we could know that it is an important factor in discovering the pattern to predict it. Third, we could know that the activity of reconstructing the data meaningfully is an important factor in discovering the pattern. Fourth, it is an important factor in finding the pattern to work organically the activity of predicting it with the activity of reconstructing the data meaningfully. We hope that this study offers the help for an in-depth understanding of students's thinking process.

• PNF and Movement
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• 제11권2호
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• pp.111-117
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• 2013

Purpose : The purpose of this study was to examine the activity of the knee flexor and extensor with ankle plantar flexion and dorsiflexion. Methods : A total of 18 subjects(Male 6, female 12) performed 4 lower extremity patterns of PNF and the activities of the vastus medialis oblique, rectus femoris, vastus lateralis, biceps femoris, semitendinosus ipsilateral sides were measured using electromyography. Results : During 4 lower extremity patterns of PNF, knee flexor and extensor muscle activity were significantly difference. Knee extensors were shown to be higher knee extension and ankle dorsiflexion combined pattern. Knee flexors were shown to be higher knee flexion and ankle plantarflexion combined pattern. Conclusion : We suggest that it is efficient to strengthening of knee extensors with ankle dorsiflexion and to strengthening of knee flexors with ankle plantar flexion. Also, for the functioning as toe standing, we have to choice appropriate movement pattern.

• PNF and Movement
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• 제14권1호
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• pp.1-6
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• 2016

Purpose: The purpose of this study was to analyze the effects of proprioceptive neuromuscular facilitation (PNF) patterns on electromyography (EMG) activity in the rectus abdominis, internal abdominal oblique, external abdominal oblique, and erector spinae according to position changes. Methods: Ten healthy adults volunteered to participate in the study. The subjects were required to complete exercises that followed two PNF extremity patterns, namely, an upper extremity extension-adduction-internal rotation pattern and a lower extremity flexion-adduction-external rotation pattern. The exercises were applied in the supine, side-lying, and sitting positions. Repeated measure one-way ANOVA and post-hoc Bonferroni correction were used to determine the influence of the patterns on muscle activity for each muscle, and descriptive statistics were then used to determine the local/global muscle ratios. Results: The upper extremity pattern had a significant effect on the rectus abdominis and erector spinae in the supine position, and on the internal oblique and external oblique in the sitting position (p<0.05). The median value for the internal oblique/rectus abdominis showed a high ratio of 2.05, and a high ratio of 1.01 was shown for the internal oblique/external oblique in the sitting position. The lower extremity pattern had a significant effect on the rectus abdominis in the side-lying position and on the internal oblique, external oblique, and erector spinae in the sitting position (p<0.05). The median value for the internal oblique/rectus abdominis showed a high ratio of 2.83 in the sitting position and a high ratio of 1.30 for the internal oblique/external oblique in the side-lying position. Conclusion: The PNF pattern increases local muscle activation in an unstable position. Therefore, when the pattern is used for intervention purposes, trunk stability and varied position changes should be taken into account.

• 대한예방한의학회지
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• 제27권2호
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• pp.35-48
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• 2023

Objective : We studied prognostic biomarkers discovery for lung cancer based on the pattern identification for the personalized Korean medicine. Methods : Using 30 tissue samples, we performed a whole exome sequencing to examine the genetic differences among three groups. Results : The exome sequencing identified among 23,490 SNPs germline variants, 12 variants showed significant frequency differences between Xu and Stasis groups (P<0.0005). As similar, 18 and 10 variants were identified in analysis for Xu vs. Gentleness group and Stasis vs. Gentleness group, respectively (P<0.001). Our exome sequencing also found 8,792 lung cancer specific variants and among the groups identified 6, 34, and 12 variants which showed significant allele frequency differences in the comparison groups; Xu vs. Stasis, Xu vs. Gentleness group, and Stasis vs. Gentleness group. As a result of PCA analysis, in germline data set, Xu group was divided from other groups. Analysis using somatic variants also showed similar result. And in gene ontology analysis using pattern identification variants, we found genes like as FUT3, MYCBPAP, and ST5 were related to tumorigenicity, and tumor metastasis in comparison between Xu and Stasis. Other significant SNPs for two were responsible for eye morphogenesis and olfactory receptor activity. Classification of somatic pattern identification variants showed close relationship in multicellular organism reproduction, anion-anion antiporter activity, and GTPase regulator activity. Conclusions : Taken together, our study identified 40 variants in 29 genes in association with germline difference of pattern identification groups and 52 variants in 47 genes in somatic cancer tissues.

• 한국연초학회지
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• 제20권1호
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• pp.80-86
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• 1998

Changes in activity and classification of esterase isozymes during the tire cycle or Plodia inteipunctella (Hiibner) were investigated by the native polyacrylamide gel electrophoresis. The stage specificity in esterase activity and isozyme pattern was observed throughout the larvalpupal-adult transformation. The activity esterase was highest at the 3-day old adult stage, and the lowest level at the prepupal stage. A total of 12 esterase bands were identified throughout the development, and the bands showing high enzyme activity was observed in the middle part of gel. Twelve esterases on the basis of inhibition by the three types of inhibitors (organophosphates, eserine sulfate and sulfhydryl reagents) were classified into three class, namely, carboxylesterase (CE), arylesterase (ArE) and cholinesterase (ChE), and these classes contained 7, 3 and 2 isozymes, respectively.

• 인터넷정보학회논문지
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• 제21권5호
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• pp.109-118
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• 2020

최근 다양한 질병 때문에 사람들은 집 안에서 많은 시간을 보내고 있다. 집 안에서 다치거나 질병에 감염되어 타인의 도움이 필요한 1인 가구의 경우 타인에게 도움을 요청하기 어렵다. 본 연구에서는 1인 가구가 집 안에서 부상이나 질병 감염 등 타인의 도움이 필요로 하는 상황인 이상 징후를 탐지하기 위한 알고리즘을 제안한다. 홈 CCTV를 이용한 영상 패턴 탐지 알고리즘과 인공지능 스피커 등을 이용한 음성 패턴 탐지 알고리즘, 스마트폰의 가속도 센서를 이용한 활동 패턴 탐지 알고리즘, 공기청정기 등을 이용한 먼지 패턴 탐지 알고리즘을 제안한다. 하지만, 홈 CCTV의 보안 문제로 사용하기 어려울 경우 음성, 활동, 먼지 패턴 센서를 결합한 융합 방식을 제안한다. 각 알고리즘은 유튜브와 실험을 통해 데이터를 수집하여 정확도를 측정했다.

• Archives of Pharmacal Research
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• 제22권4호
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• pp.335-339
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• 1999

The oxidation-reduction potentials of cosmetic raw materials, showing tyrosinase inhibitory action, and phenolic compounds structurally similar to L-tyrosine were determined by cylcic voltammetry. The voltammograms obtained could be classified ito 4 patterns (patterns 1-4). Patterns 1, characterized by oxidation and reduction peaks as a pair, was observed with catechol, hydroquinone or phenol, and pattern 2 exhibiting another oxidation peak in addition to oxidation and reduction peaks as a pair was found with arbutin, kojic acid, resorcinol, methyl p-hydroxybenzoate and L-tyrosine as the substrate of tyrosinase. Pattern 3 with an independent oxidation peak only was expressed by L-ascorbic acid, and pattern 4 with a reduction peak only at high potentials, by hinokitiol. The tyrosinase inhibitory activity of these compounds was also evaluated using the 50% inhibitory concentration ($IC_{50}$) and the inhibition constant (Ki) as parameters. Hinokitiol, classified as patterns 4, showed the highest inhibitory activity (lowest $IC_{50}$ and Ki). Hydroquinone showing the second highest activity belonged to pattern 1, which also included compounds exhibiting pattern 2 was relatively low with Ki values being in the order of 10-4 M. Although there was no consistent relationship between oxidation-reduction potentials and tyrosinase inhibitory action, the voltammetry data can be used as an additional index to establish the relationship between the structure and the tyrosine inhibitory activity.

• 한국의상디자인학회지
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• 제12권3호
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• pp.133-143
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• 2010

The purpose of this study was to investigate the clothing image according to gender, coloration of chromatic and achromatic color, and interval of checked pattern. The experimental materials developed for this study were a set of stimulus and response scales. The stimuli were 16 color pictures, in which the gender(male, female), interval(0.5cm, 1.5cm, 3.5cm, 5.5cm), and coloration(WR: white+red, WY: white+yellow, WB: white+Blue, WP: white+purple) were manipulated. The 7-point scale was used for evaluation of clothing image. Data were obtained from 192 male college students and 192 female college students living in Seoul, Gwangju, Daegu, Jinju, and Changwon on March 2010. For data analysis, ANOVA and Duncan-test were used by using SPSS program. Results of this study were as follows.; Clothing image according to coloration of chromatic and achromatic color, and interval of checked pattern consisted of six dimensions of attractiveness, appeal, activity, freshness, modesty, and cuteness. Gender showed an independent effect on attractiveness, appeal, activity, freshness, and cuteness. Interval showed an independent effect on attractiveness. Coloration showed an independent effect on appeal, activity, freshness, modesty, and cuteness. Also, interaction effects of gender and coloration on freshness and cuteness were found.

• 한국동물학회지
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• 제33권3호
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• pp.330-336
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• 1990

배추흰나비의 변태에 따른 esterase의 활성변화 및 zymogram pattern의 변화를 조사하였으며 5령말 유충으로부터 3개의 esterase를 순수 분리하였다. Esterase의 활성은 5령초에서 5령말에 이르는 동안 급격히 증가하여 5령말에서 최대의 활성이 나타났으며 전기영동의 결과 whole body와 중장내 esterase band의 수나 강도는 5령말에서 최대로 나타났다. Gel filtration과 ion-exchange chromatography 및 preparative electorphoresis를 통해 정제된 각 esterase의 최종순도는 약 30-60배였다.

• Animal cells and systems
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• 제14권2호
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• pp.73-81
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• 2010

In this study, monoclonal antibodies against lysosomal acid phosphatase (LAP) of a salamander, Hynobius leechii, were used to determine the spatial and temporal expression of the LAP in the regenerating limbs. The Western blot and immunohistochemical analysis in the limb regeneration revealed that LAP was highly expressed at the dedifferentiation stage, especially in the wound epidermis and dedifferentiating limb tissues such as muscle and cartilage. With RA treatment, the LAP expression became upregulated in terms of both level and duration in the wound epidermis, blastemal cell and dedifferentiating limb tissues. In addition, in situ activity staining of LAP showed a similar result to that of immunohistochemistry. Thus, the activity profile of LAP activity coincides well with the expression profile of LAP during the dedifferentiation period. Furthermore, to examine the effects of lysosomal enzymes including LAP on salamander limb regeneration, lysosome extract was microinjected into limb regenerates. Interestingly, when the lysosome extract was microinjected into limb regenerates with a low dose of RA($50\;{\mu}g/g$ body wt.), skeletal pattern duplication occurred frequently in the proximodistal and transverse axes. Therefore, lysosomal enzymes might cause the regenerative environment and RA plays dual roles in the modification of positional value as well as evocation of extensive dedifferentiation for pattern duplication. In conclusion, these results support the hypothesis that dedifferentiation is a crucial event in the process of limb regeneration and RA-evoked pattern duplication, and lysosomal enzymes may play important role(s) in this process.