The structure change in the broiler industry of Korea has been taking place very rapidly toward the direction of integrated production and marketing system. During the course of the evolution into the integrated structure, however, a number of small business entities, uncountable nationally but a minimum of a dozen, that previously engaged in the supply of production factors or live bird transaction also tended to get involved in the new system as a disguised or pseudo-integrator, having brought a lot of problems not only to the farmers but also to the development of integrated structure. The pseudo-integrator is generally characterized by limited functions in such a way of supplying chicks and feeds to and collecting grown birds from farmers under the contract at a fixed farmer's payment in practically the same pattern as a partial or quasi-integration, which intends to act as if an integrator in a stratagem to simply enjoy a margin simply from selling supplies and buying products for a certain period of time. The grower making a contract with appears to be a farmer who used to be an Independent and speculating but not able to join in the normal system of evolving integration. The problems of a pseudo-integrator center on the financial loss to a contract farmer, because the falsified integrator has to become easily bankrupt and run away when the price of live broiler continually stays below the cost of production, even though he is able to make a tremendous profit otherwise which is the real purpose of the operation for. It is true that the volatile market, fluctuating the price up more than doubled in a month and down to a half in a few weeks, makes the pseudo-integrator find the room for such a fraudulence. In addition, its activity also adversely affect the evolution of the integration due to rather negative image on structure change in general. It is recommended that the farmers need to better understand the real picture of the integrated system so as not to be swindled by a disguised, small scale agribusiness agent. By the same token, it is also equally required to have the whole industry integrated completely as early as possible. The Joint effort to get rid of pseudo-integrators' problems shall be put for the industry development moving toward the integration. No doubt a pseudo-integrator must be a temporary player for chance emerging during the course of structure change into the integrated, though.
For centuries, ginseng has been used for the therapeutic purpose in oriental herb medicine. Several studies have been conducted in the past to evaluate the effect of ginseng on erythropoiesis. However the results were controversial. We therefore attempted in the present studies to evaluate the effect of ginseng on the erythropoietic activity. In one series of experiments, the recovery pattern of peripheral blood(red cell count, hemoglobin content, hematocrit and reticulocyte count) was studied in posthemorrhagic anemic rabbits. After animals were maintained with normal(control group) or 1 gm% ginseng (experimental group) diet for 2 weeks, hemorrhagic anemia was induced by withdrawing blood equivalent to 25% of the total blood volume and then changes in peripheral blood were followed for following 30 days. In other series of experiments, we studied effect of ginseng on erythrokinetics using $^{59}Fe$. $^{59}Fe(10{\sim}40\;{\mu}Ci/animal)$ was injected intravenously after animals were fed with normal (control group) or 1 gm% ginseng(experimental group) diet for 2 weeks. And radioactivities in the blood compartments were measured at appropriate intervals for 15 days. Front these various erythrokinetic parameters were estimated. Results are summarized as follows: 1) Reticulocyte count was higher in the experimental group than in the control group after 2 weeks of administration of experimental diet. During the posthemorrhagic period, the reticulocyte count increased in both the control and experimental groups, but the increase appeared much earlier in the experimental group. 2) The posthemorrhagic recoveries of hematocrit, hemoglobin content and red cell count appeared to be faster in the experimental group as compaired with the control group. 3) The half life$(T_{1/2})$ of $^{59}Fe$ in the plasma was significantly(P<0.05) shorter in the experimental group(82.6 min, N=8) than in the control group(121 min, N=6). Plasma iron turnover (PIT) of the experimental group (1.78 mg/dl/24 hr.) was approximately 4 times greater than that of the control group(0.45 mg/dl/24 hr.). 4) The maximum red cell utilization(RC-U) was 82.1% in the experimental group ana 74.5% in the control group. Red cell iron turnover(RIT) of the experimental group(1.62 mg/dl/24 hr.) was slightly higher than that of the control group(0.35 mg/dl/24 hr). 5) Erythron turnover was significantly(p<0.05) greater in the experimental group(1.27 mg/dl/24 hr.) than in the control group(0.24 mg/dl/24 hr.). Marrow transit time of the experimental group(2.05 days) tended to he faster than that of the control group(2.84 days). These results suggest that the gingseng improves the recovery of posthemorrhagic anemia and stimulates the erythropoiesis in rabbits.
This study was designed to investigate the effects of varying concentrations of $CdCl_2$ on the enzyme activities such as LDH and SOD related with the accumulations of cadmium(Cd) in liver and kidney of BALB/c mice. 1. Cd accumulations in liver and kidey were increased in a dose dependent fashion. And also, this pattern was more conspicuous in kidney than that in liver. 2. LDH activities of liver and kidney were increased in a dose dependent fashion except for that of liver in 200 ppm Cd group which was similar to that of 25 ppm Cd group. 3. SOD activities of Cd exposed liver and kidney in Cd-fed mice similar to those of controls except for elevation of SOD activity of liver in 25 ppm Cd group. The results of this study suggest that the activities of various enzymes can be modulated by Cd intoxication. Acknowledgement: This study was financially supported in part by a Research Grant from Bio-Safty Research Institute, Chonbuk National University in 1997(CNU-BSRI, No. 97-03).
The total global emission of $CO_2$ from soils is recognized as one of the largest fluxes in the global carbon cycle. Especially it is necessary to quantify the amount of $CO_2$ emitted by the organic material decomposition processes of microorganisms in the soil, because it becomes one of a factor for determining the carbon stocks in the soil. This study was conducted to estimate the impact of the Korean water deer(Hydropotes inermis)' feces to the soil organic matter. Also, effects of Korean water deer' feces on $CO_2$ emissions of soil and land use pattern dependent $CO_2$ flux quantification are studied. The organic materials in the Korean water deer' feces significantly changed organic matter content of soil and influenced the activity of soil microorganisms, both changing of respiration of the soil and physical chemical components in soil. In particular, C/N ratio and the $CO_2$ flux of soil of four regions (Rice paddy, Fallow ground, Salix koreensis community, Phragmites australis community) showed a statistically highly significant correlation (P<0.01) with the presence or absence of feces. $CO_2$ flux of soil affected by the feces was 2-20 times higher than the soil unaffected by the feces. This study has great significance to quantify the extent of the material circulation and its impact to the terrestrial ecosystem and soil zone throughout Korean water deer' feces. Feces of wildlife can affect soil and soil material circulation.
In the first part of the study, rates of estrus occurrence and success of A.I. service in the Thai-native and Friesian crossbred, and purebred Friesian cows fed in the National Dairy Training and Applied Research Institute in Chiang Mai, Thailand were traced monthly throughout a year. An electric fan and a water sprinkler cooled the stall for the purebred cows during the hot season (March-September). Both rates in pure Friesians were at their highest in the cold-dry season (October- February), but they decreased steadily during the hot-dry season (March-May) and were at their lowest in the hot-wet season (June-September). Seasonal change of a similar pattern was observed in the incidence of estrus, but not in the success rate of insemination in the crossbred cows. By the use of reproductive data, compiled in the same institute, on the 75 % cross- and purebred Friesian cows, and climatological data in Chiang Mai district, effects of ambient temperature and humidity on the reproductive traits of cows were examined by regression analysis in the second half of the study. Significant relationships in the crossbred, expressed by positive-linear and parabola regressions, were found between reproductive parameters such as days to the first estrus (DTFE), A.I. service (DTFAI), and conception, the number of A.I. services required for conception and some climatic factors. However, regarding this, no consistent or intelligible results were obtained in purebred cows, perhaps because electric fans and water sprinklers were used for this breed in the hot season. Among climatic factors examined, the minimum temperature (MINT) in early lactation affected reproductive activity most conspicuously. As the temperature during one or two months prior to the first estrus and A.I. service rose, DTFE and DTFAI steadily became longer, although, when MINT depleted below $17-18^{\circ}C$, the reproductive interval tended to be prolonged again on some occasions. The maximum temperature also affected DTFE and DTFAI, but only in limited conditions. The effect of humidity was not clear, although the inverse relationship between DTFE and minimum humidity during 2 months before the first estrus in the crossbred seemed to be significant. Failure to detect any definite effect of climate on the reproductive traits of pure Friesians seemed to indicate that forced ventilation by electric fans and water sprinklers were effective enough to protect the reproductive ability of this breed from the adverse effects of a hot climate.
This study observed distribution of vegetation to confirm change of tundra-taiga boundary. Tundra-taiga boundary is used to observe the transfer of vegetation pattern because it is very sensitive to human activity, natural disturbances and climate change. The circumpolar tundra-taiga boundary could observe reaction about some change. Reaction and confirmation about climate change were definite than other place. This study used Leaf Area Index(LAI) 8-Day data in August from 2000 to 2009 that acquire from Terra satellite MODerate resolution Imaging Spectroradiometer(MODIS) sensor and used K$\"{o}$ppen Climate Map, Global Land Cover 2000 for reference data. This study conducted analysis of spatial distribution in low density vegetated areas and inter-annual / zonal analysis for using the long period data of LAI. Change of LAI was confirmed by analysis based on boundary value of LAI in study area. Development of vegetation could be confirmed by area of grown vegetation($730,325km^2$) than area of reduced vegetation ($22,372km^2$) in tundra climate. Also, area was increased with the latitude $64^{\circ}$ N~$66^{\circ}$ N as the center and around the latitude $62^{\circ}$ N through area analysis by latitude. Vegetation of tundra-taiga boundary was general increase from 2000 to 2009. While area of reduced vegetation was a little, area of vegetation growth and development was increased significantly.
Background: Inactivation in p53 tumor suppressor gene through a point mutation and deletion is one of the most frequent genetic changes found in human cancer, with 50% of an incidence. This high rate of mutation mostly suggests that the gene plays a central role in the development of cancer and the mutations detected so far were found in exons 5 to 8. Mutation of p53 locus produced accumulation of abnormal p53 protein, and negative regulation of cell proliferation and transcriptional activation as a suppressor of transformation were lost. In addition, inhibition of its normal cellular function of wild-type by mutant is an important step in tumorigenesis. Method: 4 colon cancer cell lines (SNU C1, C2A, C4, C5) were examined for mutation in exons 5 to 8 of the p53 tumor suppressor gene by PCR-SSCP analysis and expression pattern by western blotting and immunoprecipitation. p53-mediated transactivation ability were examined by CAT assay and base substitution of p53 in SNU C2A cell were detected by DNA sequencing. Results: 1) SNU C2A cell and SNU C5 cell were detected mobility shifts each in exon 5 and exon 7 of p53 gene by the PCR-SSCP method, implicating being of p53 mutation. 2) 3 colon cancer cell lines (SNU C1, SNU C2A, SNU C5) expressed wild type and mutant type p53 protein. 3) In northern blot experiment, SNU C2A and SNU C5 cell expressed high level of p53 mRNA. 4) Results of p53-mediated transactivation in colon cancer cell lines by CAT assay represented only SNU C2A cell has transcriptional activity. 5) DNA sequencing in SNU C2A cell showed missense mutation in codon 179 of one allele, histidine to arginine and wild type p53 in the other allele. Conclusion: Colon cancer cell lines showed correlation with mutation in p53 gene and accumulation of abnormal p53 protein. Colon cancer cell SNU C2A retained p53-mediated transactivation as heterozygous p53 with one mutant allele in 179 codon and the other wild-type allele.
The purpose of this study is to provide preliminary data for political measures to minimize the variations by understanding the regional variations and trends of hospital services for heart diseases, and analyzing the factors that could occur any variations. The various data collected from nation-wide inpatient services conducted separately by small region show that there have been some differences in income level, supply of medical resources, standardized rate of hospitalization by sex and age, health level in the residence, and the length of stay per head. Then it indicated that the number of special medical equipment per 10,000 people and the rate of vigorous physical activity have the highest influence over the regional variations in using hospital services. On the other hand, the number of sick-beds per 10,000 people, the number of special medical equipment, and the present smoking rate have significant degree of influence on the length of stay per head. Thus, it is imperative for the authorities to set aside health promoting policies and to distribute the medical resources equitably throughout the country and to enhance the accessibility of local residents to the health care services.
BACKGROUND/OBJECTIVES: Isoflavones are widely believed to be beneficial to human health, in relation to their antioxidant potentials. Exercise can cause an imbalance between reactive oxygen species (ROS) and antioxidants. This study was conducted in order to investigate the ability of isoflavones in amelioration of oxidative stress induced by exercise. MATERIALS/METHODS: Male Sprague-Dawley rats were assigned to one of four groups: isoflavone-free with no exercise (CON-sd), isoflavone-free with exercise (CON-ex), isoflavone-supplemented with no exercise (ISF-sd), and isoflavone-supplemented with exercise (ISF-ex). Animals exercised on the treadmill for 30 minutes per day, five days per week. TBARS as a marker of oxidative stress and antioxidant enzyme activity, including SOD, GSH-px, and catalase were determined in liver tissue. Serum lipid profile was also examined. RESULTS: A significant effect of isoflavone alone was observed on abdominal fat pad mass. ISF-ex had significantly less abdominal fat pad than CON-ex. Both exercise and isoflavone treatment had significant effects on lowering plasma triglyceride (TG), thus, the ISF-ex group had a significantly lower TG level than the CON-sd group, by 30.9%. However, no differences were observed in plasma cholesterol, HDL-C, and cholesterol/HDL-C ratio. Exercise, isoflavone, and exercise-isoflavone interaction effects were significant on thiobarbituric acid reactive substances (TBARS) (P = 0.001, 0.002, and 0.005, respectively). The CON-ex group showed a higher TBARS level than the other three groups. By contrast, in the ISF-ex group, TBARS was restored to the level of the ISF-sd or CON-sd group. Isoflavone had a significant effect on superoxide dismutase (SOD) (P = 0.022) and catalase activities (P = 0.049). Significantly higher SOD and catalase activities were observed in ISF-ex than CON-ex. SOD and catalase activities showed an inverse pattern of TBARS. Taken together, isoflavones increased the activities of SOD and catalase with concomitant decreases in TBARS, indicative of decreased oxidative stress. CONCLUSIONS: Isoflavone supplementation enhances antioxidant action with attenuation of exercise-induced oxidative stress, as measured by decreases in TBARS, and inhibits body fat accumulation and plasma TG increase. Antioxidative effects ascribed to isoflavones may be partially exerted via enhancement of antioxidant enzyme activities.
Park, Sung Ju;Seo, You Jin;Kim, Dong Wook;Choi, Hyun Jeong
Journal of the Korean earth science society
/
v.41
no.2
/
pp.111-128
/
2020
This study presents a possibility of intensification of fine dust mass concentration due to the complex urban structure using data mining technique and clustering analysis. The data mining technique showed no significant correlation between fine dust concentration and regional-use public urban data over Seoul. However, clustering analysis based on nationwide-use public data showed that building heights (floors) have a strong correlation particularly with PM10. The modeling analyses using the single canopy model and the micro-atmospheric modeling program (ENVI-Met. 4) conducted that the controlled atmospheric convection in urban area leaded to the congested flow pattern depending on the building along the distribution and height. The complex structure of urban building controls convective activity resulted in stagnation condition and fine dust increase near the surface. Consequently, the residual effect through the changes in the thermal environment caused by the shape and structure of the urban buildings must be considered in the fine dust distribution. It is notable that the atmospheric congestion may be misidentified as an important implications for providing information about the residual probability of fine dust mass concentration in the complex urban area.
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