• The Journal of Korean Physical Therapy
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• v.34 no.1
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• pp.18-25
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• 2022

Purpose: The purpose of this study was to identify changes in physical activity, sleep quality, and quality of life (QOL) during COVID-19 in adults by age group. Methods: An online survey was conducted on a total of 160 participants who were divided into three groups by age; young adults, middle-aged adults, and old adults. The participants responded to the self-reported assessment of the impact of social distancing during COVID-19, International Physical Activity Questionnaire (IPAQ), Pittsburgh Sleep Quality Index (PSQI), and Short Form-36 Health Survey (SF36). Descriptive statistics, analysis of variance, and Pearson's correlation were used for data analysis. Results: There were significant differences between the three age groups in physical activity (p<0.05) and PSQI (p<0.01) and a post hoc analysis showed that the young adults' group had significantly higher physical activity than the old adults' group, while the old adults' group had significantly lower scores of PSQI (better sleep quality) than the others. The young adults' group showed a significant negative correlation between the stress from social distancing and QOL (r=-0.27, p<0.05) and between PSQI and QOL (r=-0.48, p<0.05). For the middle-aged adults' group, there was a significant negative correlation between PSQI and QOL (r=-0.53, p<0.05). The old adults' group showed a significant negative correlation between the stress from social distancing and physical activity (r=-0.35, p<0.05) and PSQI (r=-0.50, p<0.05), while there was a significant positive correlation between physical activity and PSQI (r=0.30, p<0.05) and QOL (r=0.30, p<0.05). Conclusion: The results of this study could be used as basic data for the promotion of physical and mental health in the post-COVID-19 era.

• Journal of Fisheries and Marine Sciences Education
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• v.26 no.2
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• pp.308-315
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• 2014

The aims of this study are to analysis about surface muscle activity of lower and upper musculus erector spinae according to walkers form. The subjects of the current step is inconvenient to use a walker and five people over the age of 65 valid samples were selected as final. All the subjects were measured in three forms. Wireless EMG muscle activity is a measure of surface measurements were measured using a system, both musculus vastus lateralis, outside the erector spinae muscle, musculus biceps femoris, gastrocnemius muscle was attached to the channel electrodes. According to the results, First, gastrocnemius muscle activity showed significant differences by type of gait. Second, the muscle activity of the erector spinae muscle walking showed significant differences by type, side grip type showed the lowest muscle activity. Consequently, the present study is the efficient use of the four-wheel walker will provide the baseline data.

• Biomedical Science Letters
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• v.18 no.3
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• pp.218-226
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• 2012

Dopamine is an enteric neurotransmitter that regulates gastrointestinal motility. This study was done to investigate whether dopamine modulates spontaneous pacemaker activity in cultured interstitial cells of Cajal (ICCs) from mouse using whole cell patch clamp technique, RT-PCR and live $Ca^{2+}$ imaging analysis. ICCs generate pacemaker inward currents at a holding potential of -70 mV and generate pacemaker potentials in current-clamp mode. Dopamine did not change the frequency and amplitude of pacemaker activity in small intestinal ICCs. On the contrary dopamine reduced the frequency and amplitude of pacemaker activity in large intestinal ICCs. RT-PCR analysis revealed that Dopamine2 and 4-receptors are expressed in c-Kit positive ICCs. Dopamine2 and 4 receptor agonists inhibited pacemaker activity in large intestinal ICCs mimicked those of dopamine. Domperidone, dopamine2 receptor antagonist, increased the frequency of pacemaker activity of large intestinal ICCs. In $Ca^{2+}$-imaging, dopamine inhibited spontaneous intracellular $Ca^{2+}$ oscillations of ICCs. These results suggest that dopamine can regulate gastrointestinal motility through modulating pacemaker activity of large intestinal ICCs and dopamine effects on ICCs are mediated by dopamine2 receptor and intracellular $Ca^{2+}$ modulation.

• Journal of Korean Academy of Nursing
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• v.34 no.6
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• pp.1117-1128
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• 2004

Purpose: This study was carried out to substantiate the application process of activity-based costing on the current cost of hospital home care (HHC) service. The study materials were documents, 120 client charts, health insurance demand bills, salary of 215 HHC nurses, operating expense, 6 HHC agencies, and 31 HHC nurses. Method: The research was carried out by analyzing the HHC activities and then collecting labor and operating expenses. For resource drivers, HHC activity performance time and workload were studied. For activity drivers, the number of HHC activity performances and the activity number of visits were studied. Result: The HHC activities were classified into 70 activities. In resource, the labor cost was 245￦per minute, operating cost was 9,570￦ per visit and traffic expense was an average of 12,750￦. In resource drivers, education and training had the longest time of 67 minutes. Average length of performance for activities was 13.7 minutes. The workload was applied as a relative value. The average cost of HHC was 62,741￦ and the cost ranged from 55,560￦ to 74,016￦. Conclusion: The fixed base rate for a visit in the current HHC medical fee should be increased. Exclusion from the current fee structure or flexible operation of traveling expenses should be reviewed.

• Journal of Institute of Control, Robotics and Systems
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• v.15 no.7
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• pp.742-752
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• 2009

Engineering design involves the specification of many variables that define a product, how it is made, and how it behaves applied to computer, communication and control fields. Before some variables can be determined, other variables must first be known or assumed. This fact implies a precedence order of the variables, and of the tasks of determining these variables consequently. Moreover, design of complex systems may involve a large number of design activities. In this paper, the activity-activity incidence matrix is considered as a representation of design activity analysis which mainly focuses on the precedence constraint with an object of doing IDEF3 in process-centered view. In order to analyze the activity-activity incidence matrix, a heuristic algorithm is proposed, which transforms an activity-activity, parameter-formula, and parameter-parameter incidence matrix into a lower triangular form. The analysis of the structured matrices can not only significantly reduce the overall project complexity by reorganizing few critical tasks in practice, but also aims at obtaining shorter times considering the solution structure by exploring concurrency.

• Korean Journal of Pharmacognosy
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• v.45 no.2
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• pp.141-146
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• 2014

In this study, we investigated on antioxidative activities and tyrosinase inhibitory activities of methanol extract and its fractions from roots of Arctium lappa. The total phenolic compound and flavonoid content of the ethylacetate fraction was found to be 818.29 mg/g and 360.59 mg/g as the highest content. In the measurement of DPPH radical scavenging ability and tyrosinase inhibitory activity, the ethylacetate fraction was higher than the other fractions and the extract. In addition, comparative analysis of phenolic compounds by liquid chromatography-mass spectrometry (MS)/MS system under the multiple-reaction monitoring (MRM) with negative-ion electrospray ionization mode. The main phenolic compounds in the extract and fractions of roots from Arctium lappa were cynarin and chlorogenic acid. The main phenolic compound of the ethylacetate fraction was cynarin. n-Butanol fraction had a significantly higher chlorogenic acid content than other samples. In conclusion, DPPH radical scavenging ability and tyrosinase inhibitory activity of the cynarin-riched ethylacetate fraction showed the highest activity.

• Korean Journal of Occupational Health Nursing
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• v.22 no.1
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• pp.24-34
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• 2013

Purpose: We investigated the relationship between patient safety culture and safety care activity, and identified factors for safety care activity of entry-level nurses. Methods: The subjects of the study were 204 entry-level nurses working at five general and advanced hospitals with over 500 beds located in C and D City. The data were analyzed using descriptive analysis, t-test, ANOVA, Pearson's correlation and hierarchical multiple regression with SPSS/WIN 18.0 program. Results: Perception of patient safety culture had significant correlations with safety care activity. Multiple regression analysis showed that demographic variables of quality of nursing on patient safety and health state of entry-level nurses affected safety care activity. In addition, patient safety culture in ward and communication affected safety care activity. These factors explained 38% of variance. Conclusion: Based on the results of the study, patient safety culture promotion strategies to facilitate supportive work environment and effective communication are needed.

• Journal of the Korean Society of Physical Medicine
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• v.13 no.4
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• pp.19-25
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• 2018

PURPOSE: This study was conducted to investigate the correlation between the activity of suprahyoid muscles, infrahyoid muscles and swallowing ability in stroke patients with dysphagia. METHODS: The subjects of this study were 120 patients who were diagnosed with CT or MRI stroke and had swallowing disorder at Daegu Metropolitan General Hospital from August 2014 to February 2017. The suprahyoid and infrahyoid muscle activity was measured in patients with dysphagia and the new videofluoroscopy swallowing studies scale (new VFSS scale) was used for evaluation of swallowing function. Correlation analysis was conducted using the measured data. RESULTS: The activities of suprahyoid muscles were 325.8 (%RVC) on average, while the average infrahyoid muscle activity was 302.65 (%RVC) and the average value of the new VFSS scale was 31.52. The total for oral organs was 3.62 on average and that for pharynx organs was 28.30 on average. The activity of the suprahyoid muscles showed a significant positive correlation with the activity of the infrahyoid muscles, but a significant negative correlation with the total oral phase, total pharyngeal phase and total new VFSS scale (p<.01). The activity of the infrahyoid muscles showed a significant negative correlation with the total oral phase, total pharyngeal phase, and total new VFSS (p<.01). CONCLUSION: Based on the results of this study, it is necessary for researchers to consider the infrahyoid and suprahyoid muscles when conducting swallowing rehabilitation.

• Journal of the Korean Chemical Society
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• v.66 no.3
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• pp.194-201
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• 2022

A simple, efficient, and cost-effective method has been employed for the synthesis of 2,4,5-trisubstituted imidazole derivatives (3a-j) containing quinoline substituent at 2^nd position. Title compounds were obtained by multicomponent reaction (MCR), involving aryl substituted 1,2-diketone, quinoline carbaldehyde and ammonium acetate in the presence of acetic acid solvent under mild reaction conditions. The newly synthesized quinoline containing imidazole derivatives were confirmed through FT-IR, ¹H-NMR, ¹³C-NMR and mass spectral analysis. In-vitro microplate alamar blue assay (MABA) to determine the MIC (minimum inhibitory concentration) values against Mycobacterium tuberculosis H37Rv was performed for the synthesized compounds. The synthesized compounds exhibited activity against Mycobacterium tuberculosis and among which compounds, 3d, 3f and 3i showed good activity. The highest activity was showed with compound 3i. The anti-mycobacterial activity results are well correlated with the computational molecular docking analysis, which was performed for the synthesized compounds prior to the evaluation of the activity.

• Journal of Korea Entertainment Industry Association
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• v.14 no.8
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• pp.455-465
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• 2020

The purpose of this study was to investigate the relationship between physical activity and health-related quality of life of adults using the 7th National Health and Nutrition Survey. The study was conducted with 11,211 adults, and the health-related quality of life was defined using the EuroQol group's EQ-5D and physical activity using GPAQ. Data analysis was performed using the SAS 9.4 program, the general characteristics and degree of physical activity of the subject, Chi-square for KEQ-5D index, and Logistic Regression Analysis for the relationship between physical activity and quality of life. As a result of the study, the general characteristics of the subjects were marital status, educational status, occupation, smoking, alcohol consumption, economic status, stress, chronic disease, chronic disease treatment, physical activity due to leisure and physical activity due to occupation, depending on gender. There was a difference (p<0.05). As for the quality of life related to physical activity and health, the quality of life was significantly lower by 37% in the 'minimum physical activity group' of occupational physical activity (p<0.05). The results of this study are expected to be provided as basic data for physical activity-related health policy establishment and physical activity programs.