• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.161-169
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• 2020

The factors influencing the quality of life of physical and mental health in middle-aged women were examined. Secondary analysis was conducted using the data from the 2016 Korea Health Panel data. Method: The Korea Health Panel data 2016 were collected from February to August 2016 by the Korea Institute for Health and Social Affairs and the National Health Insurance Corporation and included 2,437 people who responded to the questionire. Using the SPSS Win program, the data were analyzed using a t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis. For physical health, the factors affecting the HRQoL were hearing problems, visual problems, eating problems, and physical activity. For mental health, the factors affecting HRQoL were suicidal impulse, stress subjective health. Conclusion: The results indicated that to improve the HRQoL of middle-aged women, a psychological nursing intervention program will be needed to reduce the stress and suicidal thoughts and improve the positive cognitive attitude and subjective health condition.

• Bulletin of the Korean Chemical Society
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• v.31 no.1
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• pp.52-58
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• 2010

Human histamine H1 receptor (HHR1) is a G protein-coupled receptor and a primary target for antiallergic therapy. Here, the ligand-based three-dimensional pharmacophore models were built from a set of known HHR1 inverse agonists using HypoGen module of CATALYST software. All ten generated pharmacophore models consist of five essential features: hydrogen bond acceptor, ring aromatic, positive ionizable and two hydrophobic functions. Best model had a correlation coefficient of 0.854 for training set compounds and it was validated with an external test set with a high correlation value of 0.925. Using this model Maybridge database containing 60,000 compounds was screened for potential leads. A rigorous screening for drug-like compounds unveiled RH01692 and SPB00834, two novel molecules for HHR1 with good CATALYST fit and estimated activity values. The new lead molecules were docked into the active site of constructed HHR1 homology model based on recently crystallized squid rhodopsin as template. Both the hit compounds were found to have critical interactions with Glu177, Phe432 and other important amino acids. The interpretations of this study may effectively be deployed in designing of novel HHR1 inverse agonists.

• The Korean Journal of Physiology
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• v.20 no.2
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• pp.257-270
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• 1986

It has been reported that the luteal function may be regulated by the intracellular calcium in luteal cells (Higuchi et al, 1976; Dorflinger et at, 1984; Gore and Behrman, 1984) which is adjusted partially by $Ca^{++}-ATPase$ activities in luteal cell membranes (Verma and Pennistion, 1981). However, the physicochemical and kinetic properties of $Ca^{++}-ATPase$ in luteal membranes were not fully characterized. This study was, therefore, undertaken to partially characterize the physicochemical and kinetic properties of $Ca^{++}-ATPase$ system in luteal membranes and microsomal fractions, known as an one of the major $Ca^{++}$ storge sites (Moore and Pastan, 1978), from the highly luteinized ovary Highly luteinized ovaries were obtained from PMSG-hCG injected immautre female rats. Light membrane and heavy membrane fractions and microsomal fractions were prepared by the differential and discontinuous sucrose density gradient centrifugation method desribed by Bramley and Ryan (1980). Light membrane and heavy membrane fractions and microsomal fractions from highly luteinized ovaries are composed of the two different kinds of $Ca^{++}-ATPase$ system. One is the high affinity $Ca^{++}-ATPase$ which is activated in low $Ca^{++}$ concentration (Km, 10-30 nM), the other is low affinity $Ca^{++}-ATPase$ activated in higher $Ca^{++}$ concentration $(K_{1/2},\;40\;{\mu}M)$. At certain $Ca^{++}$ concentrations, activities of high and low affinity $Ca^{++}-ATPase$ are the highest in light membrane fractions and are the lowest in microsomal fractions. It appeares that high affinity $Ca^{++}-ATPase$ system have 2 binding sites for ATP (Hill's coefficient; around 2 in all membrane fractions measured) and the positive cooperativity of ATP bindings obviously existed in each membrane fractions. The optimum pH for high affinity $Ca^{++}-ATPase$ activation is around S in all membrane fractions measured. The lipid phase transition temperature measured by Arrhenius plots of high affinity $Ca^{++}-ATPase$ activity is around $25^{\circ}C$. The activation energies of high affinity $Ca^{++}-ATPase$ below the transition temperature are similar in each membrane fractions, but at the above transition temperature, it is the hightest in heavy membrane fractions and the lowest in microsomal fractions. According to the above results, it is suggested that intracellular $Ca^{++}$ level, which may regulate the luteal function, may be adjusted primarily by the high affinity $Ca^{++}-ATPase$ system activated in intracellular $Ca^{++}$ concentration range $(below\;0.1\;{\mu}M)$.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.8 no.1
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• pp.81-94
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• 2001

The purpose of this study was to identify levels of activity of daily living, self-efficacy. stroke specific quality of life and need for self-help management program for patients with hemiplegia in the home. Data were collected from June to November, 2000 and subjects were 88 poststroke patients who lived in Seoul and Kyunggi-do. The questionnaire consisted of 5 scales: activities of daily living, self-efficacy, stroke specific qulaity of life and need for a self-help management program. Data were analyzed using frequencies, percent, paired t-test, and Pearson's correlation coefficient with the SAS(version 6.12) program. The results are as follows ; 1) Most of subjects were Partially independent in ADL, but they needed assist once to do dressing, bathing meal preparation and house keeping work. 2) The mean self-efficacy score was 54.89(range : 1 to 80) and the individual differences were large. 3) Subjects responded that they were satisfied on the stroke specific quality of life scale totaled 65.8%. This value is comparatively low, especially for social role(51.4%), family functioning(58.3%) and mood (62.2%). 4) The highest needs for self-help management programs were for physical therapy, stress management, and range of motion exercise and the lowest needs were for elimination management and training, family counseling, and speech therapy. 5) On the demographic variables, sex showed significant differences for the dependent variables. Females had higher scores than males for IADL, self-efficacy, stroke-specific quality of life, and need for self-help management. 6) Age had high negative correlation with ADL, self-efficacy and stroke specific quality of life. Age was also correlated with need for self-help management. In conclusion, there was a high correlation for ADL, Self-efficacy and Quality of life in poststroke patients of home. The patient with a stroke also had a strong need for self-help management programs especially physical therapy and stress management. Therefore rehabilitation programs based on self-efficacy enhancement need to be developed in order to promote independent living for patients with hemiplegia.

• The Journal of Korean society of community based occupational therapy
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• v.5 no.2
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• pp.1-9
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• 2015

Objective : This study is to investigate the correlation of Ego-degense mechanism, stress and activities of daily living of stroke patients. Methods : The study was carried out from March 14, 2014 to May 15, 2015. A survey was conducted at a university hospital and three rehabilitation hospitals located in Daegu and Busan. For statistical analysis, frequency analysis, independent sample t-test, and Pearson correlation coefficient were used in this study. Results : As a result of the mature Ego-defense mechanism grop was more stressful than immature Ego-defense mechanism group(p<.05), mechanism group also showed better performance in activities of daily living activity(p<.05). Conclusion : The higher stress in stroke patients related to the disability to perform activities of daily living. Psychosocial rehabilitation for factors such as stress as well as physical function in stroke patients in the rehabilitation of stroke patients by using the Ego-defense will have a significant impact on an individual's personality or lifestyle.

• Korean Chemical Engineering Research
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• v.53 no.3
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• pp.302-308
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• 2015

Isothermal vapor liquid equilibria for the binary system of 3-methylpentane with ethylene glycol monopropyl ether ($C_3E_1$) and ethylene glycol isopropyl ether ($iC_3E_1$) were measured at 303.15, 318.15, and 333.15K. In our previous work, phase equilibria for the binary system of $C_3E_1$ mixtures were investigated according to the chain length of alkane, alcohol or those isomer. But in this study, we discussed the different effect of $C_3E_1$ and its isomer, $iC_3E_1$, on the phase equilibria. The measured systems were correlated with a Peng-Robinson equation of state (PR EOS) combined with Wong-Sandler mixing rule for the vapor phase, and NRTL, UNIQUAC, and Wilson activity coefficient models for the liquid phase. All the measured systems showed good agreement with the correlation results. And it was found that the phase equilibria showed very little difference between the $iC_3E_1$ mixture system and the $C_3E_1$ mixture system.

• Korean Journal of Food Science and Technology
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• v.19 no.1
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• pp.29-37
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• 1987

The native myosin and paramyosin extracted from the ordinary muscle of yellowtail (Seriola quinqueradita) and the adductor muscle of whelk (Neptunea arthritica cumingi) were studied for their physico-chemical characteristics. Molecular weight, molar extinction coefficient at 278 nm and intrinsic viscosity were accounted for $4.6{\times}10^5$dalton, 5.44 in $E^{1cm}_{1%}$ and 1.60 dl/g in yellowtail myosin, and $2.0{\times}10^5$ dalton, 3.04 in $E^{1cm}_{1%}$ and 2.60 dl/g in whelk paramyosin, respectively. Yellowtail myosin showed a $0.342\;{\mu}mole-Pi/min/mg-protein$ of ${Ca}^{2+}-ATPase$ activity and contained 40 group-SH/mole-myosin. The ratio of polar amino acids to non-polar amino acids and that of acidic amino acids to basic amino acids were 0.54 and 1.64 in yellowtail moysin, and were 0.47 and 2.42 in whelk paramyosin, respectively.

• Journal of the Korean Home Economics Association
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• v.38 no.12
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• pp.131-143
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• 2000

This research aims to examine the pro-environmental food consumption behavior of two groups; the housekeepers and the restaurant cooks. The rationale for choosing these groups as target of research lies in the fact that they are expected to be the most active subject for enhancing the desirable culture of food consumption, through their close involvement in the whole process of food consumption in society. This study assumes the four areas of activity to be the meaningful categories in the investigation of the pro-environmental food consumption behaviour; planning of menu and purchasing the food materials, cooking, eating, and disposal of the leftover. By using these four categories, we attempt to provide with the empirical typology of pro-environmental food consumption behaviour and the analysis of the relations of it with socio-demographical variables. Their pro-environmental behaviors are divided into four types: $\circled1$ The positive awareness of pro-environmental cooking and eating, $\circled2$ The positive awareness of pro-environmental food consumption behavior, $\circled3$ The passive awareness of pro-environmental cooking and eating, $\circled4$ The passive awareness of pro-environmental food consumption behavior. There is no significant difference among the numbers of the cases that belong to each behavioral type. Seen in overall, however, we can say that the larger number of the cases belong to the passive type of behavior. Two socio-demographical variables of tole housekeepers and the restaurant cooks show significant corelations with the behavioral types of pro-environmental food consumption with the confidence level P<0.05, but there is no significant co-relations in other variables like gender, marital status, age, income, Engel coefficient, education. We also found that there is no great gap between the housekeepers and the restaurant cooks in their positive awareness of pro-environmental food consumption, the percentage of each group belonging to the type being 51.9% and 48.1%, respectively, but that the former shows much greater number than the latter in belonging to the passive awareness type of the pro-environmental food consumption, 75.3% and 24.7%, respectively. Although the restaurant cooks can be said to be more ego-friendly than the housekeepers, if we consider the rapidly growing trend of outgoing-diner, more efforts should be exerted to develop the education and advertisement program for enhancing the restaurant cook's pro-environmental awareness and propagating the desirable food consumption cloture.

• Microbiology and Biotechnology Letters
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• v.31 no.4
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• pp.400-407
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• 2003

In microbial coal desulfurization process (MCDP) by using Acidithiobacillus ferrooxidans, the effect of process variables on pyritic sulfur removal efficiency has been investigated. The inhibitory effect of toxic materials contained in coal matrix on the activity of desulfurizing bacteria have been evaluated in coal extracts, and the results showed that the method was useful to evaluate the applicability of a coal which is to be desulfurization to MCDP. The removal efficiency increased with decreasing particle size and decreases with increasing pulp density, but has no significant influence of particle size and pup densities at high pulp densities over 20 wt%. The mass transfers of gaseous nutrients such as oxygen and carbon dioxide into coal slurry with various pulp densities and coal particle size has been studied in an airlift bioreactor. Mass transfer coefficient was independent of pulp density in coal slurry with fine particle below 175 $\mu\textrm{m}$, but significantly decreased with increasing pulp density over 225 $\mu\textrm{m}$. The coal particles over 575 $\mu\textrm{m}$ were significantly settled to the bottom of bioreactor resulting in poor mixing. Considering mass transfer, pulp density and coal mixing, an optimal size of coal particle for the microbial coal desulfurization process seems to be about 500 $\mu\textrm{m}$.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.9
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• pp.1333-1342
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• 2008

This study intended to evaluate the visual sensibility of textiles of knitting simulation through the painting function of SDS-ONE, a computer knitting system, with the use of various fancy yarns for hand knitting. For this study, six kinds of fancy yarns with difference manufacturing style and form were selected: loop yarn, tamtam yarn, fur1 yarn, fur2 yarn, ladder yarn, and tape yarn. In order to create a computer knitting simulation, paint function of SDS-ONE was employed to scan the fancy yarns for hand knitting with a scanner. Then, after the registration of the yarns as data, the yarn was brought in for knitting simulation in plain stitch with 3 gauge. After that a survey was conducted involving 60 female experts in their twenties. Using SPSS 12.0, factor analysis, reliability, Pearson correlation coefficient, ANOVA, Duncan test, and regression analysis were performed to analyze the collected data. First, according to the result of analyzing the visual sense factor, three factors of the 'inflexibleness/ruggedness sense', 'lightweight sense', and 'smoothness sense' was extracted. According to the result of analyzing the visual sensibility factor, three factors of the 'activity', 'grace', and 'purity' was extracted. Second, With regard to preference and purchase intention, the knitted fabric with tamtam yarn(H2) was preferred than the other samples, indicating that the respondents had intention to purchase it. As for word-of-mouth intention, H2 ranked the first place, implying the respondents had intention to recommend it to other people. Third, the examination of the use of products each knitting simulation knit found that sweater and muffler are the most appropriate knit products. And H2 was the most suitable sample for sweater and muffler products. This study tried to prove that knit textile can be visually evaluated through a computer knitting simulation without the actual knitting and then to provide accurate data to related companies or the academic circle.