• Title/Summary/Keyword: Activity Coefficient

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Antitumor and Immunostimulating Activities of Acanthopanax sessiliflorus Fruits

  • Lee, Sang-Hyun;Lee, Yeon-Sil;Jung, Sang-Hoon;Ji, Jun;Shin, Kuk-Hyun;Kim, Bak-Kwang;Kang, Sam-Sik
    • Natural Product Sciences
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    • v.9 no.2
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    • pp.112-116
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    • 2003
  • The antitumor and immunostimulating activities of Acanthopanax sessiliflorus fruits were investigated. Polysaccharide isolated from this plant, when administered consecutively for 9 days at 50 and 100 mg/kg i.p. in mice, caused a significant increase in the life span and a significant decrease in the tumor weight and volume in mice inoculated with Sarcoma-180 tumor cells. Polysaccharide was also demonstrated to exhibit phagocytosis-enhancing activity as measured by the carbon clearance in mice. Polysaccharide, when administered i.p. at 50 and 100 mg/kg/day for 3 consecutive days, exhibited a significant RCtr/RCc [the rate of regression coefficient of the animals teated (RCtr) to that of the control (RCc)], being 1.44 (PI = 1), 1.52 (PI = 2) which was approximately the same with that of enhancement of phagocytosis, its potency as expressed by the regression coefficient ratio of zymosan (RCtr/RCc = 1.55, PI = 2), a typical phagocytosis enhancer. Polysaccharide also caused a significant increase in the acid phosphatase activity representing lysosomal enzymes in macrophages at 1-100 ig/ml in vitro in compliance with in vivo results. These results suggest that the antitumor activity of polysaccharide might be related to the immunostimulating function.

Orbit determination for the KOMPSAT-1 Spacecraft during the period of the solar maximum

  • Kim, Hae-Dong;Kim, Eun-Kyou;Choi, Hae-Jin
    • International Journal of Aeronautical and Space Sciences
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    • v.6 no.1
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    • pp.71-76
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    • 2005
  • The KOMPSAT-1 satellite, launched into a circular sun synchronous orbit on Dec. 21, 1999, entered its$6^{th}$year of successful operation this year. The purposes of the mission are to collect earth images (6.6 m resolution), multi-spectral images of the ocean, and to collect information on the particle environment of the low earth orbit. For normal operation, KOMPSAT-1 orbits are determined using GPS navigation solutions. However, at the start of the life of KOMPSAT-1, the 11-year solar activity cycle was at a maximum. Solar flux was maintained at this level until 2002, and thereafter reduced to a moderate level by 2004. Thus, the OD (Orbit Determination) accuracy has varied according to the solar activity. This paper presents the degree to which the OD accuracy could be degraded during a high solar activity period compared with that of a (relatively) low solar activity period. We investigated the effect of the use of solve-for parameters such as a drag coefficient ($C_D$), solar radiation coefficient ($C_R$), and the general accelerations ($G_A$) on OD accuracy with solar activity. For the evaluation of orbit determination accuracy, orbit overlap comparison is used since no independent orbits of comparable accuracy are available for comparison. The effect of the use of a box-wing model instead of a constant cross-sectional area is also investigated.

Post-ischemic Time-dependent Activity Changes of Hippocampal CA1 cells of the Mongolian Gerbils

  • Won, Moo-Ho;Shin, Hyung-Cheul
    • The Korean Journal of Physiology and Pharmacology
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    • v.11 no.6
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    • pp.247-251
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    • 2007
  • Changes of single unit activity of CA1 hippocampus region were investigated in anesthetized Mongolian gerbils for six days following transient ischemia. Ischemia was produced immediately before the implantation of micro-wire recording electrodes. In control animals receiving pseudo-ischemic surgery, neither spontaneous neuronal activities ($5.70{\pm}0.4Hz$) nor the number of recorded neurons per animal changed significantly for six days. Correlative firings among simultaneously recorded neurons were weak (correlation coefficient > 0.6) in the control animals. Animals subjected to ischemia exhibited a significant elevation of neural firing at post-ischemic 12 hr ($9.95{\pm}0.9Hz$) and day 1 ($8.48{\pm}0.8Hz$), but a significant depression of activity at post-ischemic day 6 ($1.84{\pm}0.3Hz$) when compared to the activities of non-ischemic control animal. Ischemia significantly (correlation coefficient > 0.6) increased correlative firings among simultaneously recorded neurons, which were prominent especially during post-ischemic days 1, 2 and 6. Although the numbers of spontaneously active neurons recorded from control group varied within normal range during the experimental period, those from ischemic group changed in post-ischemic time-dependent manner. Temporal changes of the number of cells recorded per animal between control group and ischemic group were also significantly different (p = 0.0084, t = 3.271, df = 10). Cresyl violet staining indicated significant loss of CA1 cells at post-ischemic day 7. Overall, we showed post-ischemic time-dependent, differential changes of three characteristics, including spontaneous activity, network relationship and excitability of CA1 cells, suggesting sustained neural functions. Thus, histological observation of CA1 cell death till post-ischemic day 7 may not represent actual neuronal death.

Measurement of Biological Activity in Pilot Scale Dyeing Wastewater Process by Using Respirometer (호흡률 측정기를 이용한 파일럿 스케일 염색폐수처리 장치에서의 생물학적 활성 측정)

  • Jeon Hyun Hee;Choi Kwang Keun;Yoon In Jun;Lee Jin Won
    • KSBB Journal
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    • v.19 no.5
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    • pp.390-393
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    • 2004
  • Oxygen uptake rate (OUR) was used as an indicator of microbial activity. In this study OUR at dyeing wastewater in the pilot plant was monitored to examine biological activity. Correlation between inlet COD concentration and maximum OUR showed that maximum OUR was proportional to inlet COD concentration. Changes in the OUR values reflected the changing waste load in the reactor. Consequently, OUR can be used to estimate biological activity of inlet COD concentration. This study showed that biodegradable COD at dyeing wastewater could be calculated from OUR and yield coefficient. Non-biodegradable COD was able to be calculated from a difference between initial COD concentration and biodegradable COD.

Factors Influencing Productive Activity and Physical and Psychological Ability in Korean Elders (노인의 생산적 활동 및 신체적.정신적 능력 영향 요인)

  • Cha, Nam-Hyun;Seo, Eun-Ju
    • Research in Community and Public Health Nursing
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    • v.21 no.1
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    • pp.128-138
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    • 2010
  • Purpose: This study was to identify the relation between productive activity and physical and psychological ability in elders. Methods: A total of 294 subjects aged between 60 and 92 were selected through convenient sampling. Data were collected with a self-reported questionnaire from May to June, 2008. Collected data were analyzed by SPSS/PC Win. 15.0. Results: Of variance in productive activity, 13.3% was explained by house ownership, number of diseases, and successful aging. Of variance in physical and psychological ability, 25.4% was explained by house ownership, perceived health, number of diseases, and successful aging. The correlation coefficient between productive activity and physical and psychological ability was significant (r=.32, p<.001) Conclusion: Findings of this study may be useful in understanding the health status of community-dwelling elders and developing more specific health promotion programs.

Serum Ornithine Carbamyl Transferase Activity in Korean (한국인(韓國人) 혈청(血淸) Ornithine Carbamyl Transferase 활성(活性)에 관(關)한 연구(硏究))

  • Tchai, B.S.
    • Journal of Nutrition and Health
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    • v.8 no.2
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    • pp.15-18
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    • 1975
  • In man, ornithine carbamyl transferase is localized mainly in the liver and to a lesser extent in the smll intestine. Because of these findings, one might expect damage only to the liver or perhaps the small intestine to cause elevated ornithine carbamyl transferase activity in serum $(_S-OCT)$. Serum ornithine carbamyl transferase activity was determined in thirty normal subjects, and fifteen patients with viral hepatitis and fifteen patients with liver cirrhosis. The correlation of $_S-OCT$ with $_S-GPT$ and $_S-GOT$ was studied. The mean $_S-OCT$ activity in thirty normal Korean subjects was $0.094{\pm}0.043$I.U./L of serum. Elevated $_S-OCT$ activity was observed in patients with liver disease. The correlation coefficient was 0.18 for $_S-OCT$ and $_S-GPT$, ana 0.40 for $_S-OCT$ and $_S-GOT$.

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Factors Influencing Physical Activity after Discharge from Hospital for Total Hip Arthroplasty Patients

  • Ju Young Kim;Mi Yang Jeon
    • Physical Therapy Rehabilitation Science
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    • v.11 no.4
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    • pp.535-545
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    • 2022
  • Objective: This study was conducted to identify predictive factors of physical activity in total hip arthroplasty patients, and to provide basic data for the developing physical activity promotion program for total hip arthroplasty patients. Design: Descriptive correlational research. Methods: Data were collected from August 2017 to May 2018. Surveys were distributed to 60 patients in a G university hospital located at J city, Gyeongsangnam-do. Data were analyzed by frequency, mean, standard deviation, t-test, ANOVA, Pearson's correlation coefficient, multiple regression analysis using SPSS 24 Win program. Results: The variables affecting the 4-week physical activity after discharge were age (β=.07), residence after discharge (β=-.22), cerebrovascular disease (β=-.13), mental and behavioural disease (β=-.11), taking antibiotic (β=-.26), walking ability (β=.41), nutritional status (β=.25), depression (β=.05). The eight variables accounted for 39.4% in the 4-week physical activity (F=4.49 p=.001). The variables affecting the 8-week physical activity after discharge were age (β=.06), waking ability (β=.34), nutritional status (β=.20), exercise self-efficacy (β=.05), depression (β=-.05). The six variables accounted for 28.0% in the 8-week physical activity (F=4.58, p<.001). Conclusions: The walking ability in discharge important to improve the physical activity, there is a need to develop an program to improve walking ability before discharge, in total hip arthroplasty. There is a need to develop a physical activity program to consistently participate in a community.

Level of physical activity and influencing factors of the first and second year nursing students (간호대학 저학년생의 신체활동정도와 영향요인)

  • Lee, Mi-Suk;Gu, Mee-Ock
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.6
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    • pp.53-67
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    • 2017
  • This study was conducted to investigate the level of physical activity and identify factors influencing physical activity of first and second year nursing students. The participants were 234 female first and second year nursing students at one nursing college located in U city. Data were collected from September 5 to 15 in 2016 and analyzed by descriptive statistics, t-test, ANOVA, $Scheff{\breve{e}}$ test, Pearson's correlation coefficient, and stepwise multiple regression using SPSS/WIN 22.0. The average level of physical activity measured by the Korean version of the Godin-Shephard Liesure-Time Exercise Questionnaire was 9.09(range 0-80). According to the physical activity group classified by leisure score index, there were 25 students(10.7%) in the active group, 31 students (13.2%) in the moderately active group, and 178 students(76.1%) in the insufficiently active group. Factors influencing the level of physical activity were intention to participate in physical activity and habit to physical activity, which together explained 21.2% of the total variance in physical activity. Therefore, this study suggests that it is necessary to develop and apply a physical activity program enhancing intention and habit to physical activity for first and second year nursing students.

Bradykinin Antagonistic Activities of Antihistamine Agents Containing Piperazine Moiety (피페라진계 항히스타민제들의 브라디키닌 길항작용)

  • 정성현;이소영;윤혜숙
    • YAKHAK HOEJI
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    • v.37 no.6
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    • pp.625-630
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    • 1993
  • Among the six antihistamine agents tested in this study, homochlorcyclizine showed the highest bradykinin antagonistic activity in the receptor binding assay as well as the isolated rat ileum assay. Schild plot analysis of bradykinin-induced ileal contraction in the presence of three different concentrations of homochlorcyclizine revealed a pA$_{2}$=6.26, and a correlation coefficient of 0.984. Homochlorcyclizine of (100 $\mu{M}$ final concentration) also showed 25% antagonistic activity in the receptor binding assay.

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Formation of PEG/Dextran Aqueous Two-Phase System for Starch Hydrolysis Using $\alpha$-Amylase ($\alpha$-Amylase로 전분 가수분해를 위한 PEG/Dextran 수성 2상계 구성)

  • 박병춘;임동준
    • Microbiology and Biotechnology Letters
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    • v.20 no.2
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    • pp.190-195
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    • 1992
  • In the polyethylene glycol/dextran aqueous two-phase systems, volume ratio was increased and partition coefficient was decreased with the increase of potyethylene glycol molecular weight and concentration. However the volume ratio was decreased and the partition coefficient was increased with the increase of dextran molecular weight. On the other hand, the volume ratio and the partition coefficient were decreased with the increase of dextran concentration. Continuous enzymatic hydrolysis of soluble starch with $\alpha$-amylase which was produced by Bacillus amyloliquefaciens IF0 14141 was investigated in polyethylene glycol/dextran aqueous two-phase systems. Nonreacted soluble starch and $\alpha$-amylase were reused in these systems. $\alpha$-Amylase activity was maintained more than 100 hrs by recycling of $\alpha$-amylase from bottom of settler to reactor.

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