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Significance of Nanotechnology and Preparation Methods of Bioactive Organic Nanoparticle (나노 기술의 중요성과 생체 활성 유기 나노 입자의 제조법)

  • Yu, Ji-Yeon;Choe, Ji-Yeon;Kim, Gi-Hyeon;Lee, Jong-Chan;Lee, Jong-Hwi
    • Journal of Dairy Science and Biotechnology
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    • v.23 no.1
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    • pp.9-17
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    • 2005
  • Nanotechnology has penetrated into the various branches of research and development and it is particularly of benefit to the particle size engineering. It has been widely known that the particle size of an active pharmaceutical ingredient (API) is critical in determining the bioavailability and processability of pharmaceutical formulation. However, the window of appropriate particle size has been limited mainly due to related processing difficulties. The windows have been widened by the recent development of nanotechnologies, resulting in diversified drug delivery systems. The impact of this development is far more fundamental than what can be expected from conventional particle size engineering. It is the case that the preparation and use of nanoparticles will soon be a common task in the particle engineering step of pharmaceutical unit operations. In this chapter, the basic principles of variouspreparation techniques will be discussed in detail. Regardless of processing details, the preparation methods of pharmaceutical nanoparticles mainly concern how to deal with the extra energy related with particle size. Depending on the ways of treating the e103 energy, preparation methods can be classified into two major classes, i.e.. thermodynamic and kinetic approaches. The recent progresses have shown the possibilities of much more complex combinations of different approaches and the use of new types of energy and nanostructures.

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Effects on Improvement of Activities of Daily Living Through Short-Term Home Visiting Physical Therapy (단기 가정방문물리치료 시행이 일상생활동작의 개선에 미치는 효과)

  • An, Duk-Hyun
    • Physical Therapy Korea
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    • v.14 no.2
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    • pp.53-60
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    • 2007
  • The objective of this study was to discover the effects of the short-term home visiting physical therapy program involving patients with some chronic brain disorders at Gimhae City, Kyongnam. Recovery of activities of daily living (ADL) is a very important factor of rehabilitative procedures, and Functional Independence Measure (FIM) is a useful standard of evaluation for it. The FIM is widely used in brain disorder research because it measures real functional activities of daily living. We applied the physical therapy exercise program twice per week (10~15 times repeatedly); a warm-up and cool down exercise performed every ten minutes by active & active-assistive ROM and stretching exercises. Main exercises were composed of getting up & laying down in bed, standing training, walking exercise in the room, and window or wall sliding exercise using affected upper limbs for a total duration of 30 minutes. We collected the data from 20 patients with chronic brain disorders at his/her home and analyzed by means of SPSS/PC+ program (Ver. 10.0). After the six week long physical therapy exercise program, the average was $56.10{\pm}22.59$ point compared with initial $50.55{\pm}19.12$ point by FIM, improved functional ADL ability about 5.55 point, and these changed scores were statistically significant (p=.000). We also studied another factor regarding patient's satisfaction. The majority of subjects (10 people) rated the program with the maximum score of ten points (50.0%), and three people rated it a seven point program (15.0%), the other two subjects gave a rating of nine and eight points (10.0%). Because the program was effective at improving the physical ADL ability and satisfaction of each subject, we suggest continual development and implementation of a home visiting physical therapy program. Further study should involve a longer period of observation with a larger population that is involved in an individually designed home physical therapy program.

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The Design and Implementation of User Interface Builder to support Software Reuse System (소프트웨어 재사용 시스템을 지원하는 사용자 인터페이스 구축기의 설계 및 구현)

  • Kim, Sang-Geun;Hong, Chan-Gi;Lee, Gyeong-Hwan
    • The Transactions of the Korea Information Processing Society
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    • v.2 no.3
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    • pp.324-334
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    • 1995
  • Most UIMS(User Interface Management System) adopt dialogue model of user interface Implementation of UIMS influenced by adopted dialogue model of user interface strongly. While the Model-View-Controller framework has contributed to many aspects of user interface development in Smalltalk environment- user interfaces generated with MVC have highly coupled model, view, and controller classes. Such coupling impedes the reuse of software component. So In this paper, we suggest MVCD model to resolve a decline of reuse with MVC have highly coupled. User messages are not changed by Controller immediately, but sent to Dialogue object which maintains the syntatic structure of the interaction. Dialogue object invokes Model object to updates is value. Since Model objects have active values, the value change propagates to the linked Controllers. Finally, Controller object convert the new value and update the View object. User interface builder is implemented on X-window with OSF/Motif that is base on this user dialogue model.

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A Study of Sustainable Architectural Design Elements Based on the Classification of Natural Elements (자연요소 중심으로 분류한 친환경 건축계획 요소에 관한 연구)

  • Yim, Su Hyun;Park, Hyeon Soo
    • KIEAE Journal
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    • v.10 no.5
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    • pp.3-12
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    • 2010
  • Sustainable design is getting to be controversial issue in all industries over the world particularly, in architecture as the amount of energy usage in architecture occupies 40%. Therefore, it is essential to make the standard for the sustainable design. In order to construct the sustainable design, firstly it should be considered that sustainable design elements based on natural resources to increase building energy efficiency is established and classified. The method of sustainable design divides into passive design and active design. Passive design method should be examined with active one simultaneously for more efficient usage of energy. Next, the study is followed how the sustainable design elements is adopted in buildings through the comparison of cases study of domestic and oversea. The result of case study shows similar adoption of sustainable design elements between oversea and domestic. However, the difference is shown in the building orientation and shape and the window size and position in Solar energy as well as high performance structure in Heat energy. These elements are the most significant elements in order to reduce energy load. In oversea, sustainable design is generated by architects, a client, and consultants based on the close cooperation in the beginning of early design phase before deciding building shape and envelope while in the domestic field adoption for sustainable design is conducted after deciding building shape and material. In order to design sustainable architecture more study is necessary in early stage for Zero Carbon and reducing building energy load through relation with specialists, a client and architects.

A Buffer Management Algorithm based on the GOP Pattern and the Importance of each Frame to Provide QoS for Streaming Services in WLAN (WLAN에서 스트리밍 서비스이 QoS를 제공하기 위한 GOP 패턴 및 프레임 중요도에 따른 버퍼 관리 기술)

  • Kim, Jae-Hyun;Lee, Hyun-Jin;Lee, Kyu-Hwan;Roh, Byeong-Hee
    • 한국정보통신설비학회:학술대회논문집
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    • 2008.08a
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    • pp.372-375
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    • 2008
  • IEEE 802.11e standardized the EDCA mechanism to support the priority based QoS. And the virtual collision handler schedules the transmission time of each MAC frame using the internal back-off window according to the access category(AC). This can provides the differentiated QoS to real-time services at the medium traffic load condition. However, the transmission delay of MAC frame for real-time services may be increased as the traffic load of best effort service increases. It becomes more critical when the real-time service uses a compressed mode video codec such as moving picture experts group(MPEG) 4 codec. That is because each frame has the different importance. That is, the I-frame has more information as compared with the P- and the B-frame. In this paper, we proposed a buffer management algorithm based on the frame importance and the delay bound. The proposed algorithm is consisted of the traffic regulator based on the dual token bucket algorithm and the active queue management algorithm. The traffic regulator reduces the transmission rate of lower AC until that the virtual collision handler can transmit an I-frame. And the active queue management discards frame based on the importance of each frame and the delay bound of head of line(HoL) frame when the channel resource is insufficient.

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Research on the Characteristics of the Light Trespass using by RELUX Program According to the Spatial Position of the Road Lightings in Residential Area Near Road (조명시뮬레이션 프로그램(RELUX)을 이용한 도로조명의 공간적 배치에 따른 침입광 영향 특성 연구)

  • Gu, Jinhoi;Jung, Jong-Hwan;Lee, Kyumok
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.26 no.11
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    • pp.1-8
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    • 2012
  • The road lightings have made our living environment safe and active, since it was first installed in 1900 in Korea. As the industry developed, various kind of road lightings have been installed in an outdoor area. But the spilt light from the road lightings have caused health problem like the sleeplessness, the depression, the failure to thrive and the nearsightedness to children. The light trespass caused by road lightings vary with the height of road lightings, the distance from road lightings to the window and the BUG rating of road lightings. In this paper, we analyze the effect on the light trespass by the spatial installation position of road lightings using by RELUX program. And we derive the characteristics of the light trespass according to the spatial installation position of the road lightings in residential area near road.

A modeling and simulation for a Small-Scaled Power Quality Compensating Equipment of Electrical Railway (전기철도용 축소형 전력품질 보상설비에 대한 모델링 및 시뮬레이션)

  • Kang, Moon-Ho;Kim, Joo-Rak;Han, Moon-Seob
    • Journal of the Korean Society for Railway
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    • v.10 no.2 s.39
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    • pp.96-102
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    • 2007
  • This paper presents a study on the control of a power quality compensating equipment of electrical railway built in small-scaled to preliminary research. Because this compensating equipment is very complicated power electronics system, consisting of a scott transformer as a power source, four single phase inverters interconnected with DC-link capacitors and various electrical apparatuses, multiple controllers and control algorithms with high performance and reliability are needed. The major function of the compensating equipment is to manage reactive and active powers by using the four single phase inverters, so, the main control effort is focused on the power flow control which realized through the decoupling current control of the four inverters. Overall control system is designed with object oriented and analyzed on a Simulink window. The simulation results show that the design scheme is very effective for a complicated control system and the proposed controller has good performance.

A 150-Mb/s CMOS Monolithic Optical Receiver for Plastic Optical Fiber Link

  • Park, Kang-Yeob;Oh, Won-Seok;Ham, Kyung-Sun;Choi, Woo-Young
    • Journal of the Optical Society of Korea
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    • v.16 no.1
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    • pp.1-5
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    • 2012
  • This paper describes a 150-Mb/s monolithic optical receiver for plastic optical fiber link using a standard CMOS technology. The receiver integrates a photodiode using an N-well/P-substrate junction, a pre amplifier, a post amplifier, and an output driver. The size, PN-junction type, and the number of metal fingers of the photodiode are optimized to meet the link requirements. The N-well/P-substrate photodiode has a 200-${\mu}m$ by 200-${\mu}m$ optical window, 0.1-A/W responsivity, 7.6-pF junction capacitance and 113-MHz bandwidth. The monolithic receiver can successfully convert 150-Mb/s optical signal into digital data through up to 30-m plastic optical fiber link with -10.4 dBm of optical sensitivity. The receiver occupies 0.56-$mm^2$ area including electrostatic discharge protection diodes and bonding pads. To reduce unnecessary power consumption when the light is not over threshold or not modulating, a simple light detector and a signal detector are introduced. In active mode, the receiver core consumes 5.8-mA DC currents at 150-Mb/s data rate from a single 3.3 V supply, while consumes only $120{\mu}W$ in the sleep mode.

Strategic Differentiation of Internationalization in the Mobile Telecommunications Industry: Case Studies

  • Kim, Whan-Seon;Lee, Myeong-Ho;Kim, Kyung-Don
    • ETRI Journal
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    • v.31 no.1
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    • pp.51-61
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    • 2009
  • We present a unified explanation of the internationalization strategies of major mobile network operators (MNOs). We have developed a framework that analyzes the strategies of major international MNOs in terms of the relationship between their degree of involvement in international business operations and the degree of equity participation. The results show a positive association between these two dimensions as expected, but they also reveal some exceptional cases in which certain MNOs are actively involved in the business operations of other foreign MNOs, even with minor (or zero) equity investments. In this paper, we argue that the strategic actions of the major MNOs which are the largest shareholders of foreign MNOs are in an equilibrium status because these major MNOs derive maximum benefit from full or considerable management control and active involvement. Finally, we predict that latecomers (MNOs who are just about to enter foreign telecommunications markets) may adopt an incremental investment approach because most developed markets and deregulated emerging markets with growth potential are already preempted by major MNOs. Therefore, the window of opportunity for internationalization in those markets is currently small.

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SINUS BONE GRAFT USING COMBINATION OF AUTOGENOUS BONE AND $BIOOSS^{(R)}$: COMPARISON OF HEALING ACCORDING TO THE RATIO OF AUTOGENOUS BONE (자가골과 $BioOss^{(R)}$를 이용한 상악동골이식술: 자가골 함량에 따른 치유 비교)

  • Kim, Young-Kyun;Yun, Pil-Young;Kim, Su-Gwan;Lim, Sung-Chul
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.33 no.6
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    • pp.654-659
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    • 2007
  • We performed sinus bone graft using some amount of autogenous bone and $BioOss^{(R)}$ and covered the sinus window with $Ossix^{(R)}$ membrane in these case series. After 4 to 6 months after operation, histopathologic examinations of trephine core biopsy showed following results. 1. There were bone density of 39.2% to 41.2% four months after operation, and we could observe the favorable early new bone formation. 2. Active bony remodeling of woven and lamellar bone was observed during 4 to 6 months healing period. 3. There were no significant differences between two groups. And also there were no significant differences between 4 months and 6 months.