• Genomics & Informatics
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• 제21권2호
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• pp.25.1-25.12
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• 2023

Adaptation of infections and hosts has resulted in several metabolic mechanisms adopted by intracellular pathogens to combat the defense responses and the lack of fuel during infection. Human tuberculosis caused by Mycobacterium tuberculosis (MTB) is the world's first cause of mortality tied to a single disease. This study aims to characterize and anticipate potential antigen characteristics for promising vaccine candidates for the hypothetical protein of MTB through computational strategies. The protein is associated with the catalyzation of dithiol oxidation and/or disulfide reduction because of the protein's anticipated disulfide oxidoreductase properties. This investigation analyzed the protein's physicochemical characteristics, protein-protein interactions, subcellular locations, anticipated active sites, secondary and tertiary structures, allergenicity, antigenicity, and toxicity properties. The protein has significant active amino acid residues with no allergenicity, elevated antigenicity, and no toxicity.

• 중국학논총
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• 제63호
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• pp.343-362
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• 2019

During the traditional periods when there were exchanges among Korea, China and Japan based on ocean currents or seasonal winds, the southwestern coastal areas including Yeosu held an important position since the route would not have been complete without them. Armed with its advantages including the marine environment, the Yeosu area in the southwestern coast on the Korean Peninsula engage in active maritime exchanges and activities as a base along the sea route since the Neolithic or Bronze Age. It was the same later when Baekje and Gaya had exchanges with China and Japan, when Unified Silla had exchanges with China, and when Goryeo had exchanges with China and Japan. In Joseon, the Yeosu area gained fame as a marine defense base. In short, the Yeosu area in the southwestern coast on the Korean Peninsula during the traditional periods not only engage in active maritime exchanges and activities, but also serve as an important base that could not be left out in the maritime history of East Asia.

• 한국디지털정책학회:학술대회논문집
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• 한국디지털정책학회 2004년도 International Conference on Digital Policy & Management
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• pp.173-184
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• 2004

E-Government security is crucial to the development of e-government. Due to the complexity and characteristics of e-government security, the viable current approaches for security focus on preventing the network intrusion or misusing in advanced and seldom concern of the forensics data attaining for the investigation after the network attack or fraud. We discuss the method for resolving the problem of the e-government security from the different side of view - network forensics approaches? from the thinking of the active protection or defense for the e-government security, which can also improve the ability of emergence response and incident investigation for e-government security.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1995년도 Proceedings of the Korea Automation Control Conference, 10th (KACC); Seoul, Korea; 23-25 Oct. 1995
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• pp.522-525
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• 1995

A manipulation of a multiple contacted object by a Rotational Base and Single-jointed Finger mechanism(RBSF mechanism) is discussed. The manipulation is characterized by multiple contacts on an object and large motions of the object with sliding contacts. The kinematics and dynamics allowing sliding at multiple contacts are explored. The conditions for manipulation of an object at multiple contacts by the RBSF mechanism, which cannot exert arbitrary contact forces because it has a fewer number of joints than is required for active control, is presented.

• 디지털콘텐츠학회 논문지
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• 제12권4호
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• pp.567-574
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• 2011

본 논문에서는 공연장이나 야구장 등 다양한 분야에서 티켓을 발권하는데 있어서 필요한 보안성과 호환성 그리고 상업성까지 기존 문제를 해결한 미래형 웹 시스템을 설계하고 구현하였다. 보안 문제로 이슈가 되고 있는 우회 해킹 기법인 스크린 해킹을 방어하고 더 강력한 보안을 위해 모바일을 이용한 OTP(One Time Password)시스템을 제시하고 호환 문제를 해결하기 위해 ActiveX를 사용하지 않는 Non-ActiveX System과 다양한 환경이나 기기에서 이용이 가능하게 기존 반응형 하이브리드 웹을 개선한 스마트 발권 시스템을 제시한다. 또한 모바일 기기의 특징을 이용한 지능형 화면 전환 시스템과 자동 할인 시스템, 최단거리 공연장 안내 시스템으로 상업적인 부분까지 고려하여 완성도 높은 시스템을 제시하였다.

• 한국항공우주학회지
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• 제46권8호
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• pp.687-693
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• 2018

본 연구는 능동형 안테나 시스템의 안정적인 임무수행을 위하여 열적 신뢰성을 고려한 방열설계에 관한 연구이다. 능동형 안테나는 송수신부에 고성능의 고발열 소자들이 존재한다. 안테나의 성능 유지를 위해서는 방열설계를 통해 고발열 소자들에서 발생하는 열을 효과적으로 제거하고, 적정한 온도범위에서 동작할 수 있도록 하여야 한다. 능동형 안테나의 송수신부는 고발열부로 액체냉각을 이용한 방열이 효과적이다. 본 연구에서는 능동형 안테나의 열적 성능을 만족하기 위하여 액체냉각 시스템을 포함한 방열설계를 수행하였으며, 이를 수치해석을 통해 분석, 검증하였다.

• 전자공학회논문지CI
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• 제45권5호
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• pp.201-208
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• 2008

능동형 RFID 시스템은 금속재질에 취약한 수동형의 단점을 극복하는 동시에 인식거리가 길고, 인식률이 좋아 항만물류나 국방 분야에서 사용이 확대되고 있다. 하지만 동일한 표준으로 개발된 제품의 서로 간에 인식이 불가능한 사례가 보고되고 있으며, 국제적으로 정확한 평가방법 및 장치가 정립되지 않아 개발된 제품들 간의 상호 운용성 및 표준 적합성 평가에 대한 어려움이 존재한다. 본 논문에서는 능동형 RFID 시스템의 적합성 평가를 위한 에뮬레이터의 하드웨어 및 소프트웨어를 설계하고 제작하였다. 설계된 장치는 Matlab의 Simulink를 통한 시뮬레이션으로 성능을 분석하였고, 실제 능동형 RFID 태그의 표준 적합성 평가를 통해 에뮬레이터의 적용 가능성을 검증하였다.

• 산업경영시스템학회지
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• 제39권4호
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• pp.49-59
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• 2016

Naval combat system developed in-country is progressing at an alarming rate since 2000. ROK navy will be achieved all vessels that have combat system in the near future. The importance of System Engineering and Integrated Logistics Support based on reliability analysis is increasing. However, reliability analysis that everyone trusted and recognized is not enough and applied practically for development of Defense Acquisition Program. In particular, Existing Reliability Analysis is focusing on reliability index (Mean Time Between Failure (MTBF) etc.) for policy decision of defense improvement project. Most of the weapon system acquisition process applying in the exponential distribution simply persist unreality due to memoryless property. Critical failures are more important than simple faults to ship's operator. There are no confirmed cases of reliability analysis involved with critical failure that naval ship scheduler and operator concerned sensitively. Therefore, this study is focusing on Mean Time To Critical Failure (MTTCF), reliability on specific time and Operational Readiness Float (ORF) requirements related to critical failure of Patrol Killer Guided missile (PKG) combat system that is beginning of naval combat system developed in-country. Methods of analysis is applied parametric and non-parametric statistical techniques. It is compared to the estimates and proposed applications. The result of study shows that parametric and non-parametric estimators should be applied differently depending on purpose of utilization based on test of normality. For the first time, this study is offering Reliability of ROK Naval combat system to stakeholders involved with defense improvement project. Decision makers of defense improvement project have to active support and effort in this area for improvement of System Engineering.

• Journal of Advanced Marine Engineering and Technology
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• 제38권7호
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• pp.844-853
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• 2014

수상함정에 사용되는 능동소나는 통상적으로 구상선수부에 설치하게 된다. 따라서 구상선수부에 설치된 소나의 항해 중 유체력 및 수중 부유물에 의한 충돌 파손을 막기 위해 밀도가 낮으면서 강도가 높은 복합소재 재질의 소나돔 윈도우를 설치하게 된다. 외부 유체력 및 충격 발생 시 소나돔 윈도우의 안정도는 소나돔 윈도우 내외부의 압력 분포에 따라 달라지므로 본 연구에서는 소나돔 충, 배수 밸브의 상태에 따른 소나돔 윈도우의 내외부 압력변화를 해석적으로 검토하고 이에 따른 응력변화를 파악하고자 한다.

• 대한한방내과학회지
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• 제38권6호
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• pp.877-890
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• 2017

Objectives: Lonicerae flos (LF), a dried flower part of Lonicera japonica Thunb., has been widely used in Korean medicine as anti-inflammatory and antioxidative agent. The purpose of this study was to determine the cardioprotective effects of LF, through potential antioxidant effects, on the pressure overload (PO)-induced heart failure (HF) in C57BL/6 mice after transverse aortic constriction (TAC) surgery. Methods: Resveratrol (10 mg/kg body weight) or LF (125, 250 or 500 mg/kg body weight) was orally administered, once daily for 14 days, starting 14 days after TAC surgery. Changes in the mortality, body weights, heart weights, histopathology of the heart, and antioxidant defense systems of the heart were analyzed. Results: Marked and noticeable increases of heart weights, mortalities, and hypertrophic, focal, and lytic fibrotic histological changes in the LVs were observed, with destruction of heart antioxidant defense systems after surgery. However, HF signs, induced by TAC surgery through PO, and destruction of heart antioxidant defense systems were significantly and dose-dependently inhibited by 14 days of maintained oral treatment with LF 500, 250 or 125 mg/kg. Treatment with 250 mg/kg LF was comparable to treatment with 10 mg/kg resveratrol. Conclusions: The results in this study suggest that oral administration of LF favorably relieves PO-induced HF following TAC, through increase of heart antioxidant defense systems. The overall effects of 250 mg/kg LF were similar to those of 10 mg/kg resveratrol. More detailed mechanistic studies should be conducted in the future, with screening of the biologically active compounds in LF.