• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.11
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• pp.5005-5011
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• 2011

The purpose of this work is to know the validity of a new stimulation method in cognitive functional imaging using custom-designed images correspond to words or syllables improving the shortcomings of existing method using text. From March 2011 to May five Subjects in need of language related functional MRI scanning were selected and both of text stimulating method and image stimulating method sacanning were carried out three times each. Using 3.0T Philps MRI machine and Invivo Co's Eloquence system, data acquisition was performed with EPI-BOLD technique. Post processing was performed with SPM 99 while the activated signals were determined within 95 percent confidence level.The number of activation clusters and the activation ratio inside ROI were compared. As as result, all of the subject showed activation inside Broca area but it did not have statistical significance. In conclusion, the image sitimulation method has potential because image itself is a common means of recognition and it can be recognised easily even if there language barrier. This stimulation method can be applied to replacing the exising scanning method especially in the elderly, infants, foerigners who may not fully understand about the examination.

• The Korean Journal of Physiology and Pharmacology
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• v.1 no.4
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• pp.445-456
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• 1997

We previously reported that some components of ginsenosides decreased mediator releases evoked by the activation of mast cells with specific antigen-antibody reactions. This study aimed to assess the effects of ginsenosides ($Rb_2$, Re) on the mechanism of histamine release in the mast cell activation. We partially purified guinea pig lung mast cells by using enzyme digestion, the rough and the discontinuous percoll density gradient method. Mast cells were sensitized with $IgG_1$ and challenged with ovalbumin (OA). Histamine was assayed by fluorometric analyzer, leukotrienes by radioimmunoassay. Phospholipase D (PLD) activity was assessed more directly by the production of $[^3H]phosphatidylbutanol$ (PBut) which was produced by PLD-mediated transphosphatidylation in the presence of butanol. The amount of 1,2- diacylglycerol (DAG) were measured by the $[^3H]DAG$ labeled with $[^3H]palmitic$ acid or $[^3H]myristic$ acid. Pretreatment of $Rb_2$ ($300\;{\mu}g$) significantly decreased histamine release by 60%, but Re ($300\;{\mu}g$) increased histamine release by 34%. Leukotrienes release in $Rb_2$ was decreased by 40%, Re was not affected in the leukotrienes release during mast cell activations. An increasing PLD activity during mast cell activation was decreased by the dose-dependent manner in the pretreatment of $Rb_2$, but Re pretreatment facilitated the increased PLD activity during mast cell activation. The amount of DAG produced by phospholipase C (PLC) activity was decreased by $Rb_2$ pretreatment, but Re pretreatment was not affected. The amount of mass DAG was decreased by $Rb_2$ and Re pretreatment during mast cell activation. The data suggest that $Rb_2$ purified from Korean Red Ginseng Radix inhibits the DAG which is produced by the activation of mast cells with antigen-antibody reactions via both phosphatidylinositide-PLC and phosphatidylcholine-PLD systems, and then followed by the inhibition of histamine release. However, Re increases histamine release by stimulation of DAG production, which is mediated by phosphatidylcholine-PLD system rather than by phosphatidylinositide-PLC system, but inhibits the mass DAG production. Thus, it could be inferred that other mechanisms play a role in the increase of histamine release during mast cell activation.

• The Journal of Korean Academy of Prosthodontics
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• v.52 no.3
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• pp.195-201
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• 2014

Purpose: This study was designed to compare the amount of polymerization shrinkage of dual-cure resin cements according to different polymerization modes and to determine the effect of light activation on the degree of polymerization. Materials and methods: Four kinds of dual-cure resin cements were investigated: Smartcem 2, Panavia F 2.0, Clearfil SA Luting and Zirconite. Each material was tested in three different polymerization modes: self-polymerization only, immediate light polymerization and 5 minutes-delayed light polymerization. The time-dependent polymerization shrinkage-strain was evaluated for 30 minutes by Bonded-disk method at $37^{\circ}C$. Five recordings of each material with three different modes were taken. Data were analyzed using one-way ANOVA and multiple comparison Scheffe′test (${\alpha}$=.05). Results: All materials, except Panavia F 2.0, exhibited the highest polymerization shrinkage-strain through delayed light-activated polymerization. No significant difference between light activation modes was found with Panavia F 2.0. All materials exhibited more than 90% of polymerization rate in the immediate or delayed light activated group within 10 minutes. Conclusion: As a clinical implication of this study, the application of delayed light activation mode to dual-cure resin cements is advantageous in terms of degree of polymerization.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.5
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• pp.187-193
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• 2020

The purpose of this study is to study the methodology of deriving a policy that activates artificial intelligence from the governmental perspective in order to induce corporate growth by effectively grafting artificial intelligence technology into society and thereby improve individual and national competitiveness by creating new jobs. In order to derive activation plans, 1) detailed investigation of the domestic environment, 2) discovery of priority support fields and models that can be applied to artificial intelligence, 3) preparation of guidelines for activation and introduction, 4) specific methods for promoting and activating artificial intelligence Should be presented. The proposed artificial intelligence activation method performs a procedure to verify and confirm the effectiveness of artificial intelligence nurturing through a multi-faceted approach. The multi-faceted analysis approach includes business ecosystem aspects, industry-specific aspects including companies, technology fields, policy aspects, public and non-public services aspects, government-led and private-led aspects. Therefore, it can be reviewed as a method of inducing activation in various forms. In the future research field, it is necessary to prove the effectiveness of the proposed activation plan based on empirical data on artificial intelligence-based services. The expected effect of this study is to contribute to support the development of artificial intelligence technology and to establish related policies.

• Tuberculosis and Respiratory Diseases
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• v.43 no.3
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• pp.359-366
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• 1996

Background : Eosinophilic leukocytes are prominent cellular participants in the pathogenesis of allergic disease and asthma. Chemotaxis is still a very useful method in evaluating the response of human eosinophil to novel modulators. Degranulated mast cells and activated T lymphocytes are responsible for the pathophysiology of asthma and tryptase is one of most important proteases released after activation of mast cells. The purpose of this study was to investigate the actions of trypsin and chymotrypsin on eosinophils in terms of chemotaxis and activation. Method : Eosinophils were isolated by negative immunoselection from the peripheral blood of atopic donors. Chemotaxis was studied by using micro-Boyden chambers and ECP release was assayed by fluoroimmunoassay. Results : Eosinophil showed a chemotactic response to trypsin. Maximal chemotactic response was with $1000{\mu}g/ml$ trypsin ($56.52{\pm}14.50$/HPF) which was comparable to PAP. But chymotrypsin showed no significant chemotactic response to eosinophils. Trypsin at the concentration of 10, 100, $1000{\mu}g/ml$ induced secretion of ECP, which at the concentration of $10{\mu}g/ml$ represented about 2.7 times of the spontaneous rate of release. Soybean protease inhibitor reduced trypsin induced ECP release. Conclusion : Trypsin can induce chemotactic response to eosinophils and activation of eosinophils that can induce secretion of ECP. On the contrary, chymotrypsin showed no direct effect on eosinophils. We propose a role of trypsin on the chemotaxis and activation of eosinophils.

• Journal of Embryo Transfer
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• v.32 no.1
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• pp.25-31
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• 2017

This study was conducted to investigate the effect of activation method on the endoplasmic reticulum (ER) stress induction, apoptosis and in vitro development of porcine parthenogenetic embryos. Porcine in vitro matured oocytes were activated by four activation methods; 1) electric stimulus (ES) (E), 2) $ES+10{\mu}M$ Ca-ionophore (A23187) treatment (EC), 3) ES+2 mM 6-dimethylaminopurine (6-DMAP) treatment (ED), or 4) ES+A23187 and 6-DMAP treatments (ECD). Parthenogenetic embryos were sampled to analyze x-box binding protein 1 (Xbp1) mRNA, ER stress-associated genes and apoptosis genes at 3 h after ES and the 1-cell and blastocyst stages. In the EC group, the band intensity of spliced Xbp1 (Xbp1s) mRNA was higher than those of the other groups at the 3 h and 1-cell stage, and higher than that of the E group at the blastocyst stage. Four ER stress-associated genes were expressed at the highest level in the EC group and weakly expressed in the ED group at 3 h after activation. However, most of the genes were highly expressed at the 1-cell and blastocyst stages with some variation in the EC and ECD groups. Expression of Bcl-2-associated X protein (Bax) and caspase-3 mRNA was significantly higher in the EC group than in the other groups at all development stages. The developmental rates to the blastocyst stage were higher in the ED and ECD groups than in the E and EC groups. These results suggest that the intracellular ER stress of parthenogenetic porcine embryos is affected by the activation method and subsequently lead to the apoptosis of embryos.

• Clean Technology
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• v.29 no.4
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• pp.272-278
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• 2023

There is a lot of interest in methods for pollutants using adsorption, and recent research is being conducted to show that biochar can be used to remove organic and inorganic pollutants. In particular, wood waste as waste biomass requires a biomass recycling method, and a method to increase the adsorption capacity of biochar produced using wood waste is needed. Biochar is created by Hydrothermal carbonization (HTC) using, which uses low temperature and high pressure, has low energy consumption and does not require moisture removal pretreatment, and biochar is created through chemical activation using KOH, NaOH, and ZnCl₂ chemicals. The adsorption characteristics of biochar were determined by analyzing iodine adsorptivity, specific surface area, pore diameter, pore volume, pore distribution, and SEM according to the activation. The results of analyzing the selecting biochar by activating the biochar produced at HTC 300℃, 4 hr by KOH, NaOH, and ZnCl₂ chemicals, the specific surface area was 774~1.387 m²/g, showing a high specific surface area similar to activated carbon, and it was confirmed that micropores with an average pore diameter in the range of 21~24 Å were formed. As a result of SEM observation, the surface was uniform with a certain shape depending on activation. It was confirmed that one pore was developed and the number of pores increased.

• Korean Journal of Applied Biomechanics
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• v.25 no.2
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• pp.219-229
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• 2015

Objective : The purpose of this study was to analyze EMG according to surface type and elastic band usage during the pilates Superman movement. Method : The subjects were 10 female university students with a mean age of 27. The independent variables were surface type (yoga mat, air filled equipment, elastic mat) and elastic band usage. In order to measure muscle activity, the Noraxon(USA) was used. Eight muscles (upper trapezius, lower trapezius, thoracic spine, lumbar spine, gluteus maximus, gluteus medius, biceps femoris, semitendinosus) activation were analyzed. For the statistical analysis, MANOVA, independent t-test and Scheffe test for the post-hoc via SPSS 20.0 was used. Results : The left and right upper trapezius muscle activities were significantly reduced when using the elastic bands. In addition gluteus medius muscle activities significantly increased with the elastic band as well. Conclusion : According to the usage of the elastic band and the different types of surfaces, different muscle groups were recruited. Elastic bands were found to have more activation on the gluteus medius muscle meanwhile there was less activation on the upper trapezius during the pilates Superman movement.

• Proceedings of the Korea Committee for Ocean Resources and Engineering Conference
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• 2003.10a
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• pp.146-151
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• 2003

Reduced Activation Ferritic/Martenstic (RAFs) are leading candidates for structural materials of D-T fusion reactor. One of The RAFs, JLF-1 (9Cr-2W-V, Ta) has been developed and proved to have good resistance against high-fluency neutrino irradiation and good phase stability. Recently, in order to clarify the strengthening mechanical at high temperature, a new scheme to improve high temperature mechanical properties is desired. Therefore, the creep properties and creep life prediction by Larson-Miller Parameter method for JLF-1 to be used for fusion reactor materials or other high temperature components were presented at the elevated temperatures of $500^{\circ}C$, $550^{\circ}C$, $600^{\circ}C$, $650^{\circ}C$ and $704^{\circ}C$. It was confirmed experimentally and quantitatively that a creep life predictive e벼ation at such various high temperatures was well derived by LMP.

• Transactions of the Korean hydrogen and new energy society
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• v.4 no.1
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• pp.11-19
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• 1993

The kinetic studies of the hydrogen induced amorphization in $ErCo_2$ Laves phase is observed by the internal standard method using X-ray diffraction intensities. The activation energy and rate constant exponent for the amorphization in $ErCo_2$ are found to be 26 kcal/mole and 0.78, respectively. From these results, it is believed that the mechanism of the hydrogen induced amorphization in $ErCo_2$ is related to the motion of Co atoms. Though there are many similar physical properties between $ErCo_2$ and $ErNi_2$, the activation energy for the amorphizatin in $ErCo_2$ is larger than that in $ErNi_2$ and the amorphization rate in $ErCo_2$ is slower. It is suggested that these differences of activation energy for the hydrogen induced amorphization and the amorphization rate between $ErCo_2$ and $ErNi_2$ is due to the occurence of structural change on forming crystalline hydride.