• Title/Summary/Keyword: Activation Products

검색결과 639건 처리시간 0.028초

Isolation of inhibitors of NF-$\kappa$B activation by UV stimuli in transfectant HaCaT cells from Acanthopanacis sessilifflorum

  • Kim, Seong-Kie;Kim, Yeong-Shik;Ahn, Kwang-Seok;Ryu, Shi-Yong;Heor, Jung-Hee;Kim, Young-Sup
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.390.3-391
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    • 2002
  • Nuclear-kappa B(NF-$\kappa$B) plays a role in the regulation of genes responsible for inflammatory and immune responses as well as growth control of cells. A cell-based assay system for guiding NF-KB activity was developed to determine the influence of activated NF-KB in human keratinocytes. It suggested that this system could be used to determine the quantitative measurement of NF-$\kappa$B activity in the human skin and allow the monitoring of anti-inflammatory agent for dermatological means from various environmental stimuli. (omitted)

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연구로 해체시 발생되는 흑연폐기물의 열적 거동 (Thermal Behavior of the Nuclear Graphite Waste Generated from the Decommissioning of the Nuclear Research Reactor)

  • 양희철;은희철;이동규;조용준;강영애;이근우;오원진
    • 한국방사성폐기물학회:학술대회논문집
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    • 한국방사성폐기물학회 2004년도 학술논문집
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    • pp.105-114
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    • 2004
  • This study investigated the thermal behavior of the nuclear graphite waste generated from the decommissioning of the Korean nuclear research reactor, The first part study investigated the decomposition rate of the nuclear graphite waste up to $1000^{\circ}C$ under various oxygen partial pressures using a thermo-gravimetric analyzer (TGA). Tested graphite waste sample not easily destroyed in the oxygen-deficient condition. However, the gas-solid oxidation reaction was found to be very effective in the presence of oxygen. No significant amount of the product of incomplete combustion was formed even in the limited oxygen concentration of 4% $O_2$. The influence of temperature and oxygen partial pressure was evaluated by the theoretical model analysis of the thermo-gravimetric data. The activation energy and the reaction order of graphite oxidation were evaluated as 128 kJ/mole and 1.1, respectively. The second part of this study investigated the behavior of radioactive elements under graphite oxidation atmosphere using thermodynamic equilibrium model. $^{22}Na$, $^{134}Cs$ and $^{137}Cs$ were found be the semi-volatile elements. Since volatile uranium species can be formulated at high temperatures above $1050^{\circ}C$, the temperature of incinerator furnace should be minimized. Other corrosion/activation products, fission products and uranium were found to be the non-volatile species.

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왕겨 및 톱밥을 이용한 활성탄 제조 및 계면활성제 흡착성능 (Manufacturing Activated Carbon from Rice Shell or Saw Dust and Their Adsorption Performance for the Surfactants)

  • 김태영;백일현;윤영균;정노희;남기대
    • 한국응용과학기술학회지
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    • 제15권1호
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    • pp.79-90
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    • 1998
  • One of the objectives of this study were to develop a process for manufacturing activated carbons from agricultural by-products(rice shells and saw dust) and another is to measure the iodine number, ash content and removal ratio of COD. The other is to compare those values with those of commercialized activated carbons. Agricultural by-products based activated carbons were manufactured through the steam-reaction method. A rotary kiln type furnace was used for both carbonization and activation. The optimum operating temperatures for carbonization and activation were $650^{\circ}C$ and $900^{\circ}C$, respectively. For the activated carbons produced under these conditions, the iodine number was 1,127mg/g. Especially, removal efficiency of COD was 61.5% for 40mg/L of wastewater and 30% for 150mg/L of SLS(Sodium Lauryl Sulfate).

Radial and Circumferential Variations in Hygroscopicity and Diffusion Coefficients within a Tree Disk

  • Kang, Wook;Chung, Woo Yang;Eom, Chang Deuk;Han, Yeon Jung;Yeo, Hwan Myeong;Jung, Hee Suk
    • Journal of the Korean Wood Science and Technology
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    • 제35권2호
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    • pp.29-38
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    • 2007
  • This study was undertaken to investigate the variation of equilibrium moisture content (EMC) in transverse direction and three different directional (longitudinal, radial, and tangential) linear movements, and diffusion coefficients within a tree disc of Korean red pine (pinus densiflora). The EMC gradually increased in heartwood from pith. Therefore, the chemical components might differ even in heartwood and the radial variation in EMC might have a close relationship with the cellulose content within a cross section. The specific gravity increases gradually from pith and the porosity has not direct influence on the variation of EMC within a tree disk. Both the radial and tangential diffusion coefficients exhibited clear trend of increase from pith. The EMC change (${\Delta}EMC$) and tangential diffusion coefficient were close to be axisymmetrical but others were deviated from axisymmetry. The diffusion coefficient decreases with decreasing an activation energy and specific gravity, The diffusion coefficient increased with increasing ${\Delta}EMC$ and hygroscopicity of wood might be inversely proportional to the activation energy, The fJEMC may depend on the chemical constituents of cellulose, hemicellulose and lignin. As the number of sorption sites and sorption capacity of wood increase, therefore, it might be assumed that the hygroscopicity of wood increases while activation energy decreases. Modeling physico-mechanical behavior of wood, the variations should be considered to improve the accuracy.

Cell Motility Is Decreased in Macrophages Activated by Cancer Cell-Conditioned Medium

  • Go, Ahreum;Ryu, Yun-Kyoung;Lee, Jae-Wook;Moon, Eun-Yi
    • Biomolecules & Therapeutics
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    • 제21권6호
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    • pp.481-486
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    • 2013
  • Macrophages play a role in innate immune responses to various foreign antigens. Many products from primary tumors influence the activation and transmigration of macrophages. Here, we investigated a migration of macrophages stimulated with cancer cell culture-conditioned medium (CM). Macrophage activation by treatment with CM of B16F10 cells were judged by the increase in protein levels of inducible nitric oxide synthase (iNOS) and cyclooxygenase 2 (COX2). The location where macrophages were at 4 h-incubation with control medium or CM was different from where they were at 5 h-incubation in culture dish. Percentage of superimposed macrophages at every 1 h interval was gradually increased by CM treatment as compared to control. Total coverage of migrated track expressed in coordinates was smaller and total distance of migration was shorter in CM-treated macrophages than that in control. Rac1 activity in CM-treated macrophages was also decreased as compared to that in control. When macrophages were treated with CM in the presence of dexamethasone (Dex), an increase in COX2 protein levels, and a decrease in Rac1 activity and total coverage of migration were reversed. In the meanwhile, biphasic changes were detected by Dex treatment in section distance of migration at each time interval, which was more decreased at early time and then increased at later time. Taken together, data demonstrate that macrophage motility could be reduced in accordance with activation in response to cancer cell products. It suggests that macrophage motility could be a novel marker to monitor cancer-associated inflammatory diseases and the efficacy of anti-inflammatory agents.

화학제품 제조업에서 발생한 VOC의 탈착반응 연구 (Study on Desorption Reaction of VOC Produced from Manufacturing of Chemical Products)

  • 박근익;윤성민;김주연;길인섭;박희재;이영우
    • 공업화학
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    • 제21권5호
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    • pp.505-508
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    • 2010
  • 시화/반월 산단 내에서 활성탄 흡착탑을 사용하는 업종 중 기타 화학제품 제조업종에서 수거한 폐활성탄의 탈착반응 특성을 조사하였다. 탈착특성을 조사하기 위하여 열중량분석기(Thermogravimetric Analyzer, TGA)가 사용되었다. 탈착 반응특성 비교에 중요한 요소인 반응차수와 활성화 에너지를 구하기 위하여 Friedman법과 Freeman-carroll법을 사용하였다. 기타 화학제품 제조업종에서 수거한 폐활성탄으로 Friedman법을 이용하여 활성화 에너지를 계산한 결과, 24.8~46.5 kJ/moL을 나타내었으며, Freeman-carroll법을 이용하여 반응차수와 활성화 에너지를 계산한 결과, 반응차수는 0.11~1.69, 활성화 에너지는 8.77~32.26 kJ/moL이었다.

농산물 직거래 유통채널별 저해요인 분석과 활성화 방안 (Analysis of Factor Hindering and Promotion Strategy on the Direct Marketing of Agricultural Products)

  • 김덕현;박길석;이수영;이승현
    • 유통과학연구
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    • 제14권12호
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    • pp.71-78
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    • 2016
  • Purpose - This paper is for the Analysis on the Hindrance Factors and Activation Scheme by the Type of Distribution Channel in Direct transaction of Agricultural Products. As the distribution structure of agricultural products has become changable, farmers seem to use the type of direct distribution in order to enhance the receiving price. This study aims to explore the hindrance factors and income variation rate in direct transaction of agricultural produces, specifically focusing on the 167 farmers. Research design, data, and methodology - To ascertain the hindrance factors exactly by the type of distribution channel, the managements were classified by four subcategories, that is high sales percentage with shopping malls, SNS, shopping malls and SNS, and off-line direct transaction. Results - As a result of the hypothesis test, hinderance factors in online direct deal activation were found to be in the order of the difficulty in continuous content production, the difficulty in shopping mall operation and maintenance, and the difficulty in card commission problems, and in the order of the difficulties in continuous content production, the difficulty in continuous content production, the difficulty in shopping mall operation and maintenance, and the difficulty in branding for the SNS group. Thus, it can be seen that the difficulty in continuous content production, shopping mall operation and maintenance were found to be the biggest obstacles. In addition, hindering factors in online direct deal activation were found to be in the order of the difficulty in credit card settlement, the difficulty in publicity, and the difficulty in dealing with unsold goods. The group with high sales rate in shopping mall was found to be increased by 23.9% in the gross income compared to the previous year, the group with high SNS sales ratio increased by 56.5%, the group with direct offline transaction increased by 37.1%, among which the group with the highest increase rate of SNS sales ratio was found to be the highest from the rate of increase/decrease of the income, which was statistically significant. Conclusions - It can be suggested that government and local government may provide agricultural management with supporting plan which in turn can activate direct transaction in any possible ways.

데이터 마이닝을 이용한 농산물 전자상거래의 온 오프라인 통합시스템 (Integrated System of On-Off Line in Agricultural Products Electronic Commerce Based on Data Mining)

  • 주종문;황승국
    • 한국산업경영시스템학회:학술대회논문집
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    • 한국산업경영시스템학회 2002년도 춘계학술대회
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    • pp.171-176
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    • 2002
  • The Internet, as a commercial tool, provided a new market that connects producers to consumers through I-commerce. 2-commerce through the Internet became a new trend in all industries. This research indicates problems that block the activation of I-commerce of agricultural products, which is less developed than the other industries. To solve the problems it suggests E-commerce for agricultural products combining on and off line markets. It also suggests data mining technique for analyzing entire information in system.

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곤충 생약으로부터 항응고 및 항혈전 물질의 탐색 (Evaluation of Anticoagulant and Fibrinolytic Activities from Crude Extracts of Insects)

  • 한범수;우숭지;김성환;김영식
    • 생약학회지
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    • 제30권4호
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    • pp.409-412
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    • 1999
  • The in vitro anticoagulant and fibrinolytic activities of crude extract from insects which have been used as traditional medicines. The extracts of Formica, Huechys and Eupolyph-aga/Steleophaga prolonged activated partial thromboplastin time and thrombin time compared to the value of the control. The fibrinolytic activity of insect extracts was also tested by fibrin plate method. We found that the extracts of Cicadae Periostracum, Eupolyphaga/Steleophdga, Mantidis $O{\ddot{o}}otheca$ and Huechys directly could hydrolyze the fibrin clot without the activation of plasminogen by plasminogen activators.

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황화 $Ni-W/\gamma-Al_2O_3$ 촉매에 의한 Dibeenzothiophene의 수첨탈황반응 (Hydrodesulfurization of Dibenzothiophene by Sulfided $Ni-W/\gamma-Al_2O_3$ Catalyst)

  • 김경림;정지원
    • 한국대기환경학회지
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    • 제2권2호
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    • pp.51-59
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    • 1986
  • Hydrodesulfurization of dibenzothiophene (DBT) dissolved in n-heptane was studied over sulfided $Ni - W/\gamma - Al_2O_3$ catalyst at temperature ranges from 513 to 573 K and at pressure ranges from 20 to 60 x $10^5$ Pa. Hydrogenation of biphenyl (BP) and cyclohexylbenzene (CHB) observed in products were also run. The products were almost biphenyl and cyclohyxylbenzene, and the conversion of DBT was very sensitive to temperature. Concerning the products distribution while the formation of biphenyl decreased, the formation of cyclohexylbenzene increased in the range of high pressure. The reaction network was found to be sequential reaction which formed cyclohexybenzent through the intermediate of biphenyl. The disappearances of DBT and biphenyl were the first order with respect to DBT and biphenyl and their activation energys were 24.3 and 13.6 Kcal/mol, respectively.

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