• Title/Summary/Keyword: Activation Model

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A Simulation Study on Cardiac Activation Process Using the Three Dimensional Ventricular Model (3차원 심실모델을 이용한 심장의 활성화 과정에 대한 시뮬레이션 연구)

  • Lee, Kyoung-Joung;Park, Gum-Soo;Yun, Hyung-Ro
    • Journal of Biomedical Engineering Research
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    • v.13 no.2
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    • pp.97-106
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    • 1992
  • The cardiac activation process uslng three dimensional ventricular model is simulated. To study this theme, we constructed a cardiac ventricular model and simulated the cardiac activation process using the action potential duration and the activation time. The cardiac ventricular model is generated by the loglcal combination of the elliptic equations. The action potential duration could be obtained from the fact that It Is linearly distributed between model cells. The cardiac activation process was simulated by the law of "all-or-none". Based on the activation time and the action potential duration the cardiac potential at the arbitrary time after the activation of the model cell was computed. To test the validity of model, the comparison of the results of model simulation with the physiological data was performed. In conclusion, this model shows the simular results which is comparable to the 1 Pal conduction of the cardlac excitation.xcitation.

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A Real Time Automated Diagnosis Algorithm of Electrocardiogram Based-on Microcomputer (마이크로 컴퓨터를 이용한 실시간 ECG 자동진단 알고리즘)

  • 윤형로;최경훈
    • Journal of Biomedical Engineering Research
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    • v.6 no.1
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    • pp.55-64
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    • 1985
  • The cardiac activation process using three dimensional ventricular model is simulated.To study this theme, we constructed a cardiac ventricular model and simulated the cardiac activation process using the action potential duration and the activation time. The cardiac ventricular model is generated by the logical combination of the elliptic equations. The action potential duration could be obtained from the fact that it is linearly distributed between model cells. The cardiac activation process was simulated by the law of "all-or-none" Based on the activation time and the action potential do-ration the cardiac potential at the arbitrary time after the activation of the model cell was computed. To test the validity of model, the comparison of the results of model simulation with the physiological data was performed. In conclusion, this model shows the simular results which is comparable to the real conduction of the cardiac excitation.xcitation.

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Characteristics analysis of Word Superiority Effect in Korean using Interactive Activation Model (Interactive Activation Model(IAM)을 이용한 한글에서의 Word Superiority Effect(WSE)특성 분석)

  • Park, Chang-Su;Bang, Sung-Yang
    • Annual Conference on Human and Language Technology
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    • 1999.10e
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    • pp.343-350
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    • 1999
  • 본 논문은 한글에서 나타나는 Word Speriority Effect의 특성을 설명해 주는 한글의 글자 인지모델을 제안한다. 제안된 모델은 영어에서 나타나는 Word Superiority Effect를 설명하기 위해서 제안된 Interactive Activation Model을 기초로 한다. 우선은 영어에 맞도록 설계된 Interactive Activation Model을 한글에 적용할 수 있도록 수정하는 방법에 대해서 알아본다. 다음으로 한글에서 나타난 Word Superiority Effect의 특징과 그러한 특징을 기존의 Interactive Activation Model에 반영하기 위한 방법에 대해 알아본다. 제안된 방법을 이용해서 수정된 Interactive Activation Model을 컴퓨터로 구현해서 모의실험한 결과를 분석함으로써 제안된 모델의 타당성을 검증하게 된다.

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Simulation of the cardiac depolarization based on three dimensional ventricular model. (3차원 심실모델을 이용한 심장의 탈분극 시뮬레이션)

  • Lee, K.J.;Yoon, H.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1992 no.11
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    • pp.146-149
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    • 1992
  • The cardiac depolarization model using three dimensional ventricular model is simulated. To study this theme, we constructed a cardiac ventricular model and simulated the cardiac activation process using the action potential duration and the activation time. The cardiac potential model is generated by the logical combination of the elliptic equations. The action potential duration could be obtained from the fact that it is linearly distributed between model cells. The cardiac activation process was simulated by the law of "all-or-none". Based on the activation time and the action potential duration the cardiac potential at the arbitrary time after the activation of the model cell was computed. To test the validity of model, the comparison the results of model simulation with the physiological data was performed.

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Evolutionary Model of Depression as an Adaptation for Blocked Social Mobility

  • Park, Hanson;Pak, Sunyoung
    • Korean Journal of Biological Psychiatry
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    • v.29 no.1
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    • pp.1-8
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    • 2022
  • Objectives In regard to the social competition hypothesis, depression is viewed as an involuntary defeat strategy. A previous study has demonstrated that adaptation in microenvironments can result in a wide range of behavioural patterns including defense activation disorders. Using a simulation model with evolutionary ecological agents, we explore how the fitness of various defence activation traits has changed over time in different environments with high and low social mobility. Methods The Evolutionary Ecological Model of Defence Activation Disorder, which is based on the Marginal Value Theorem, was used to examine changes in relative fitness for individuals with defensive activation disorders after adjusting for social mobility. Results Our study examined the effects of social mobility on fitness by varying the d-values, a measure of depression in the model. With a decline in social mobility, the level of fitness of individuals with high levels of defense activation decreased. We gained insight into the evolutionary influence of varying levels of social mobility on individuals' degrees of depression. In the context of a highly stratified society, the results support a mismatch hypothesis which states that high levels of defence are detrimental. Conclusions Despite the fact that niche specialization in habitats composed of multiple microenvironments can result in diverse levels of defensive activation being evolutionary strategies for stability, decreased social mobility may lead to a decrease in fitness of individuals with highly activated defence modules. There may be a reason behind the epidemic of depression in modern society.

Prediction of Concrete Compressive Strength by a Modified Rate Constant Model (수정 반응률 상수 모델에 의한 콘크리트 압축강도의 예측)

  • 한상훈;김진근;문영호
    • Journal of the Korea Concrete Institute
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    • v.12 no.2
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    • pp.31-42
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    • 2000
  • This paper discusses the validity of models predicting the compressive strength of concrete subjected to various temperature histories and the shortcomings of existing rate constant model and apparent activation energy concept. Based on the discussion, a modified rate constant model is proposed. The modified rate constant model, in which apparent activation energy is a nonlinear function of curing temperature and age, accurately estimates the development of the experimental compressive strengths by a few researchers. Also, the apparent activation energy of concrete cured with high temperature decreases rapidly with age, but that of concrete cured with low temperature decreases gradually with age. Finally generalized models to predict apparent activation energy and compressive strength are proposed, which are based on the regression results.

Prediction of Concrete Strength by a Modified Rate Constant Model (수정 반응률 상수 모델에 의한 콘크리트의 강도의 예측)

  • 한상훈;김진근
    • Proceedings of the Korea Concrete Institute Conference
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    • 1999.10a
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    • pp.155-158
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    • 1999
  • This paper discusses the validity of models to predict the compressive strength of concrete subjected to various temperature histories and the shortcomings of existing rate constant model and apparent activation energy concept. Based on the discussion, a modified rate constant model is proposed. The modified rate constant model, in which apparent activation energy is a nonlinear function of curing temperature and age, accurately estimates the development of the experimental compressive strengths by a few researches. Also, the apparent activation energy of concrete cured with high temperature decreases rapidly with age, but that cured with low temperature decreases gradually with age. Finally a generalized model to predict apparent activation energy and compressive strength is proposed, which is based on the regression results.

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Estimation of Cardiac Pumping Performance according to the Ventricular Electrical Activation Time Distribution by Using Physiome Model (피지옴 모델을 이용한 심실의 전기활성시간 분포에 따른 심박출 성능평가)

  • Kim, Hyeong-Gyun;Lim, Ki Moo
    • Journal of Biomedical Engineering Research
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    • v.36 no.5
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    • pp.198-203
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    • 2015
  • The purpose of the study is to examine the effects of pacemaker location on cardiac pumping efficacy theoretically. We used a three-dimensional finite element cardiac electromechanical model of canine ventricles with models of the circulatory system. Electrical activation time for normal sinus rhythm and artificial pacing in apex, left ventricular free wall, and right ventricular free wall were obtained from electrophysiological model. We applied the electrical activation time maps to the mechanical contraction model and obtained cardiac mechanical responses such as myocardial contractile ATP consumption, stroke work, stroke volume, ejection fraction, and etc. Among three artificial pacing methods, left ventricle pacing showed best performance in ventricular pumping efficacy.

Comparison of Adsorption Properties of Adsorbates on Pt(111) and Pt(111)/$\gamma-Al_2O_3$ Surface in the Ethylene Hydrogenation Reaction : MO-Theory

  • 조상준;박상문;박동호;허도성
    • Bulletin of the Korean Chemical Society
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    • v.19 no.7
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    • pp.733-737
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    • 1998
  • Using an atom superposition and electron delocalization molecular orbital (ASED-MO) method, we have compared adsorption properties of adsorbates on the Pt(Ill) surface with the Pt(lll)/γ-Al203 surface in the ethylene hydrogenation reaction. In two-layer thick model systems, the calculated activation energy of the hydrogenation by the surface platinum hydride is equal to the energy by the hydride over supported platinum/γ-alumina. The transition structure on platinum is very close to the structure on the supported platinum/γ-alumina surface. Hydrogenation by the surface hydride on platinum can take place easily because the activation energy is about 0.5 eV less than hydrogenation by ethylidene. On supported platinum/,y-alumina the activation energy of the hydride mechanism is about 0.61 eV less than that of ethylidene mechanism. In one-layer thick model systems, the activation energy of hydrogenation by ethylidene is about 0.13 eV less than the activation energy of hydride reaction. The calculated activation energy by the hydride over the supported platinum y-alumina is 0. 24 eV higher than the platinum surface. We have found from this result that the catalytic properties of one-layer thick model systems have been influenced by the support but the two-layer thick model systems have not been influenced by the support.

Prediction of Compressive Strength of Fly Ash Concrete by a New Apparent Activation Energy Function (새로운 겉보기 활성에너지 함수에 의한 플라이애시 콘크리트의 압축강도 예측)

  • 한상훈;김진근;박연동
    • Proceedings of the Korea Concrete Institute Conference
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    • 2001.05a
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    • pp.947-952
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    • 2001
  • The prediction model is proposed to estimate the variation of compressive strength of fly ash concrete with aging. After analyzing the experimental result with the model, the regression results are presented according to fly ash replacement content and water/cement ratio. Based on the regression results, the influence of fly ash replacement content and water/cement ratio on apparent activation energy was investigated. According to the analysis, the model provides a good estimate of compressive strength development of fly ash concrete with aging. As the fly ash replacement content increases, the limiting relative compressive strength and initial apparent activation energy become greater. The concrete with water/cement ratio smaller than 0.40 shows that the limiting relative compressive strength and apparent activation energy are nearly constant according to water/cement ratio. But, the concrete with water/cement ratio greater than 0.40 has the increasing limiting relative compressive strength and apparent activation energy with increasing water/cement ratio.

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