• 한국초등과학교육학회지:초등과학교육
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• 제24권2호
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• pp.174-182
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• 2005

The purpose of this study was to analyze the professionalism of elementary school teachers and to draw out factors which elementary teachers should try to improve their professionalism for environmental education. For the study, both Quantitative analysis and qualitative methodologies were applied: First, randomly selected 483 elementary teachers from Seoul and Gyeonggi self responded to 5 evaluation areas by Hungerford et al. (1994) to evaluate their environmental education professionalism through the use of five point Likert scale. Second, 2 elementary teachers' environmental classes were observed for the purpose of analyzing strengths and weaknesses in classroom instruction, and then the results of self-evaluation on environmental education professionalism and teacher professionalism as shown in the classes were compared. It was found that 483 elementary teachers including 2 teachers fer analyzing classroom instruction who performed a self-evaluation gave themselves mid-scores on the Hungerford et al.'s 5 evaluation areas. However, the result of self-evaluation did not correspond with the result of actual class observation and teacher interview. That is, the actual environmental classes conducted by 2 teachers did not seemed to reflect the evaluation areas which were the foundation of the study: the conceptual awareness, the investigation & evaluation, environmental action skills, and educational application. The results of this study can be used as the basis reference to develop teaching-learning program and in-service programs for professional development of teachers for successful application of environmental education in elementary school classes.

• 한국과학교육학회지
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• 제41권2호
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• pp.115-131
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• 2021

전 지구적으로 기후변화 위기 상황이 고조되고 있는 오늘날 사회적 행동을 통해 사회를 변화시킬 수 있는 '기후변화를 주제로 한 사회적 실천지향 SSI 교육'의 필요성이 증가하고 있다. 본 연구는 사회문화적 관점을 바탕으로, 기후변화를 주제로 한 사회적 실천지향 SSI 수업을 실행하는 과정에서 직면하는 교사의 어려움이 무엇인지 탐색하고자 하였다. 이를 위해 46차시 동안 진행된 수업에 대한 질적 단일 사례연구를 진행하였으며, 연구 참여자와의 심층 면담, 교사 성찰일지, 수업 동영상, 학생 면담, 학습 결과물, 참여 관찰일지 등과 같은 질적 자료를 수집하였다. 수집된 자료는 실천적-평가적 차원의 구조를 micro(교실), meso (학교), macro (한국 사회) 장으로 나누어 분석하였다. 연구 결과 micro 장에서 새로운 시도의 수업으로 인해 기후변화에 대한 학생들의 이해나 인식을 파악하기 힘들었으며 특히 학생들이 기후변화를 나의 문제라고 인식하는 주인의식을 가지는 데 어려움이 있어 교사가 원하는 방향으로 수업이 이루어지지 않았다. 또한, 학생들은 스스로를 어린이로 위치 지으며 계획한 사회적 행동의 실현 가능성에 대해 회의적이거나, 사회적 행동을 이해하지 못하고 그 가치에 대해 공감하는 데 어려움을 겪어 학습 목표를 성취시키는 데 어려움이 있었다. meso 장에서는 동학년 교사와 교육과정을 비슷하게 운영해야 하는 학교 문화 속에서 교사만의 교육과정을 운영하는 데 어려움을 겪었다. 또한, 기후변화 수업이라는 낯선 과학 수업 주제에 대한 부담을 드러내는 동료 교사들과 소통이 단절된 채 교육과정을 홀로 운영하는 과정에서 전문성을 키워나가는 데 어려움을 겪었다. 관리자 역시 사회적 행동에 대한 소극적인 지원을 하여 학교 밖으로 사회적 행동을 실행하는 과정에서 갈등 상황에 직면하였다. 마지막으로 macro 장에서는 본 수업의 교수학습을 지원하는 물적 자원이 미흡하였으며, 학생들의 사회적 행동에 대한 사회구성원들의 제한된 시각이 교수학습상황의 거시적 제약조건으로 작용하고 있었다. 분석을 위해 유목화된 각 장의 제약조건들은 실제로는 독립적이고 분절적인 요소가 아닌 상호 간에 영향을 미치며 복합적인 그물망을 형성하며 구조적 제약조건을 형성하고 있었다. 이에 본 연구 결과를 통해 기후변화를 주제로 한 사회적 실천지향 SSI 수업을 실행하는데 교육 공동체 여러 주체의 다층적인 지원과 노력이 필요함을 시사한다.

• Clinical and Experimental Reproductive Medicine
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• 제27권1호
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• pp.9-14
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• 2000

Objective: The sperm acrosome reaction is a $Ca^{2+}$-dependent exocytotic event that is triggered by adhesion to the mammalian egg's zona pellucida. Previous studies suggested a role of $Ca^{2+}$ channels in acrosome reactions. This study was conducted to investigate the T-type calcium channel is operated in acrosome reaction of human spermatozoa. Method: Human semen samples were obtained from healthy donors with normal criteria. The spermatozoa were divided into five groups: Group 1 were non-treated as a control; Group 2 where spermatozoa were exposed to 5 ${\mu}M$ $Ca^{2+}$ A23187 $(Ca^{2+}i)$; Group 3 where spermatozoa were exposed 5 ${\mu}M$ $Ca^{2+}i$ and mibefradil; Group 4 where spermatozoa were exposed 5 ${\mu}M$ $Ca^{2+}i$ and nifedipine, and Group 5 where spermatozoa were treated with 5 ${\mu}M$ $Ca^{2+}i$ and both of mibefradil and nifedipine. Spermatozoa in all groups were retrieved after incubation for 15 and 30 minutes at $37^{\circ}C$. After staining with PSA-FITC, fluorescence was observed under a fluorescence microscope, and AR was evaluated on a total>100 spermatozoa/side. Result and Conclusion: We observed on acrosome reaction inhibition rate in human spermatozoa the various of concentration of mibefradil, nifedipine. Maximum response was noted with 1.0 ${\mu}M$ mibefradil and the decrease of acrosome reaction inhibition rate 45%. Nifedipine in acrosome reaction inhibition rate was only about 25%. The $Ca^{2+}i$-induced AR of spermatozoa was significantly suppressed by mibefradil. Incidence of the suppression was depending on concentration of mibefradil. Results from the present study suggest that the human spermatozoa possess T-type channel. The observation that reversible inhibitor of T channels in male germ cells provides a new mechanism of contraceptive action.

• 수산해양교육연구
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• 제20권3호
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• pp.343-357
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• 2008

Generally, schooling is implemented by instruction in the classroom. And instruction is made progress by concrete interaction through teacher's question and students' answer or presentation. According to a lot of researches on teacher-student interaction, student's opportunity of class presentation is influenced by students' self-esteem, learning attitude, academic achievement, and relationships. And students' opportunity of class presentation is very important not only students but also social equality and democracy. Therefore, teachers have to recognize the importance of students' opportunity of class presentation. However, according to many referential researches, students' opportunity of class presentation is differentiated by students' academic ability and social-economic status. The purpose of this study was to ascertain whether students' opportunity of class presentation was differentiated by students' academic ability and social-economic status or not. The method of this study was used checklist, interview, and class observation for a month. This study indicates that in spite of some exceptional cases, many students were taken the opportunity of class presentation differently by his/her academic ability and social-economic status. And teacher does not recognize that whether she gives student's opportunity of class presentation differently or not. To be a good teacher, teacher should reflect that teaching students is not easy, and teaching students is very important. And teacher should recognize that her speaking, action, and interaction with students including students' opportunity of class presentation influences students' self-esteem, learning attitude, academic achievement, and relationships.

• 한국융합학회논문지
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• 제9권9호
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• pp.293-297
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• 2018

본 연구의 목적은 활동관찰이 지적장애청소년의 볼링수행에 미치는 영향을 알아보는데 있다. 본 연구에 선정된 피험자들은 D시 소재 특수학교에 재원 중인 14-16세의 경도지적장애청소년을 연구대상으로 선정하였다. 대상자들은 모두 사회성숙도(SQ) 지수가 60-70사이를 나타내었으며 이는 IQ(K-WISC)가 55-69 사이에 포함되는 것으로 경도지적장애로 판별된다. 실험에 참여하는 동안 피험자들은 볼링의 각 프레임이 시작하기 전에 1분간의 활동관찰 내용을 3분 동안 반복적으로 시청을 하고, 볼링 60프레임을 수행하였다. 이 연구의 실험설계는 2(집단)${\times}$ 6(회기)에 대해 반복측정 이원분산분석과 파지단계 점수는 one-way ANOVA로 분석했다. 종속변수는 볼링점수이다. 연구문제와 관련된 통계적 유의수준은 ${\alpha}=.05$로 하였으며, 사후분석에는 Turkey's HSD를 사용하였다. 통계적 자료 분석은 SPSS 21.0 프로그램을 사용하였다. 본 연구결과 활동관찰집단이 통제집단보다 볼링점수가 유의하게 높게 나타났다. 이러한 결과는 비디오 형태의 모델링에서 관찰학습이 지적장애인의 볼링기술 습득 및 학습을 향상시킬 수 있는 가능성이 있다는 것을 보여주었다고 판단된다.

• Biomolecules & Therapeutics
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• 제15권1호
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• pp.16-26
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• 2007

Tissue plasminogen activator (tPA) is a serine protease catalyzing the proteolytic conversion of plasminogen into plasmin, which is involved in thrombolysis. During last two decades, the role of tPA in brain physiology and pathology has been extensively investigated. tPA is expressed in brain regions such as cortex, hippocampus, amygdala and cerebellum, and major neural cell types such as neuron, astrocyte, microglia and endothelial cells express tPA in basal status. After strong neural stimulation such as seizure, tPA behaves as an immediate early gene increasing the expression level within an hour. Neural activity and/or postsynaptic stimulation increased the release of tPA from axonal terminal and presumably from dendritic compartment. Neuronal tPA regulates plastic changes in neuronal function and structure mediating key neurologic processes such as visual cortex plasticity, seizure spreading, cerebellar motor learning, long term potentiation and addictive or withdrawal behavior after morphine discontinuance. In addition to these physiological roles, tPA mediates excitotoxicity leading to the neurodegeneration in several pathological conditions including ischemic stroke. Increasing amount of evidence also suggest the role of tPA in neurodegenerative diseases such as Alzheimer's disease and multiple sclerosis even though beneficial effects was also reported in case of Alzheimer's disease based on the observation of tPA-induced degradation of $A{\beta}$ aggregates. Target proteins of tPA action include extracellular matrix protein laminin, proteoglycans and NMDA receptor. In addition, several receptors (or binding partners) for tPA has been reported such as low-density lipoprotein receptor-related protein (LRP) and annexin II, even though intracellular signaling mechanism underlying tPA action is not clear yet. Interestingly, the action of tPA comprises both proteolytic and non-proteolytic mechanism. In case of microglial activation, tPA showed non-proteolytic cytokine-like function. The search for exact target proteins and receptor molecules for tPA along with the identification of the mechanism regulating tPA expression and release in the nervous system will enable us to better understand several key neurological processes like teaming and memory as well as to obtain therapeutic tools against neurodegenerative diseases.

• 한국식품위생안전성학회지
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• 제19권3호
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• pp.161-166
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• 2004

We investigated the antiplatelet effect of a newly synthesized guanidine derivative KR-32558, a sodium-hydrogen exchanger-1 (NHE-1) inhibitor, together with the elucidation of the possible mechanisms of action. KR-32558 concentration -dependently inhibited the aggregation of washed rabbit platelets induced by collagen (10 ${\mu}g/ml$) with an $IC_{50}$ value of 85.9 ${\mu}M$, but with much weaker potency against aggregation induced by thapsigargin (0.5 ${\mu}M$) or A23187 (5 ${\mu}M$). And had no effect on platelet aggregation induced by arachidonic acid (100 ${\mu}M$), thrombin (0.05 U/ml) and U46619 (1 ${\mu}M$) up to 100 ${\mu}M$. KR-32558 completely inhibited the $[Ca^{2+}]_i$ mobilization induced by collagen at concentration of 100${\mu}iM$. Taken together, these observation suggest that KR-32558 selectively inhibited collagen-mediated platelet aggregation by blocking the cytoplasmic calcium mobilization in addition to NHE-1 inhibition.

• 한국표면공학회지
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• 제45권1호
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• pp.25-30
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• 2012

The galvanostatic tests for corrosion protection are conducted at various applied current densities during 93,600 sec, and evaluated in terms of the variations in current density with time and in the potential at the applied current density. In addition, the corrosion damage depth is analyzed with 3D analysis optical microscope after galvanostatic tests. In this study, it was investigated to decide condition of the corrosion protection gavalnostatic method for Cu-Al alloy that has an excellent corrosion resistance. In the galvanostatic test under the cavitation environment, the energy was reflected or cancelled out by the collision with the oxygen gas generated by the oxygen reduction action. The surface observation showed neither the cavitation damage nor the electrochemical damage in the current density over 0.01 $A/cm^2$ in the dynamic state under the cavitation environment.

• 이베로아메리카
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• 제22권2호
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• pp.153-179
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• 2020

In the Mexican territory the cultural diversity is associated with the environmental diversity, this is demonstrated by the presence of native groups that inhabit the regions of the country, which are characterized by the management of various natural resources that they obtain from the terrestrial and aquatic environments of each of the regions. Through the RECREA Model: complex thinking, information and communication technologies and research-action, complemented with fundamentals of geography, environmental geography, cultural ecology, field work and cartographic information, we explained and analyzed the association between environmental diversity and cultural diversity to demonstrate that in Mexico there are still links between the environment, society and culture, a situation that determines the existence of human groups that subsist in the context of a global capitalist system that extracts in an unsustainable way natural resources. Based on these results, an instructional model is made to put it to practice with international students, in this case from Japan and South Korea, to allow the observation of its functionality in transmitting the aforementioned results on environmental and cultural diversity in Mexico during the teaching-learning process.

• Journal of Forest and Environmental Science
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• 제33권1호
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• pp.8-21
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• 2017

The objective of this study is to identify the individual characteristics and the elements of social capital hence a suitable design of social capital reinforcement can be proposed to promote a sustainable community-based mangrove management. The research conducted in three villages that were selected based on mangrove ecological differences in Lampung Province, Indonesia. Qualitative data was collected through field observation and in-depth interviews with key informants. The results showed that the population in the three villages dominated on productive ages, worked as farmers, and less educated (only a half of the population had fulfilled the basic education standard of Indonesia). The study results also indicated that the social capital in the communities showed minimum condition of interpersonal attachment and cooperation. This condition was derived from the attitude of the people who only took personal benefit without concerning to others' welfare. Many programs conducted by government to ensure the conservation of mangroves were project-oriented with minor participation of community. The minor participation might also contributed to the minimum of social capital in the community. To improve social capital, the communities should strengthen mutual trust based on mutual benefit to increase members' participation in mangrove activity.