• Archives of Plastic Surgery
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• 제44권4호
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• pp.293-300
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• 2017

Background Simulation training is becoming an increasingly important component of skills acquisition in surgical specialties, including Plastic Surgery. Non-living simulation models have an established place in Plastic Surgical microsurgery training, and support the principles of replacement, reduction and refinement of animal use. A more sophisticated version of the basic chicken thigh microsurgery model has been developed to include dissection of a type 1-muscle flap and is described and validated here. Methods A step-by-step dissection guide on how to perform the chicken thigh adductor profundus free muscle flap is demonstrated. Forty trainees performed the novel simulation muscle flap on the last day of a 5-day microsurgery course. Pre- and post-course microvascular anastomosis assessment, along with micro dissection and end product (anastomosis lapse index) assessment, demonstrated skills acquisition. Results The average time to dissect the flap by novice trainees was $82{\pm}24$ minutes, by core trainees $90{\pm}24$ minutes, and by higher trainees $64{\pm}21$ minutes (P=0.013). There was a statistically significant difference in the time to complete the anastomosis between the three levels of training (P=0.001) and there was a significant decrease in the time taken to perform the anastomosis following course completion (P<0.001). Anastomosis lapse index scores improved for all cohorts with post-test average anastomosis lapse index score of $3{\pm}1.4$ (P<0.001). Conclusions The novel chicken thigh adductor profundus free muscle flap model demonstrates face and construct validity for the introduction of the principles of free tissue transfer. The low cost, constant, and reproducible anatomy makes this simulation model a recommended addition to any microsurgical training curriculum.

• 대한한의학방제학회지
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• 제25권1호
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• pp.69-87
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• 2017

Objectives : Cheongnoemyeongsin-hwan (CNMSH) is a herb medicine to treat cognitive impairment. This study was investigated the effects of CNMSH on learning and memory impairment induced by cerebral hypoperfusion. Cerebral hypoperfusion was produced chronically by permanent bilateral common carotid artery occlusion (BCCAO) in rats. Methods : CNMSH was administered orally once a day (250 mg/kg) for 28 days starting at 4th week after the BCCAO. The acquisition of learning and the retention of memory were tested on 9th week after the BCCAO using the Morris water maze. In addition, effect of CNMSH on neuronal apoptosis and ${\beta}-amyloid$ accumulation in the hippocmapus was evaluated with immunohistochemistry and Western blotting. Results : 1. CNMSH and ChAL significantly shortened the escape latencies on the 2nd day of acquisition training trials. 2. ChAL significantly prolonged the swimming time spent in the target and peri-target zones and CNMSH also significantly prolonged the swimming time spent in the peri-target zone. 3. CNMSH and ChAL significantly increased the number of target heading in the retention test. 4. ChAL significantly shortened the time of the 1st target heading in the retention test, but CNMSH insignificantly shortened the time of that. 5. CNMSH and ChAL significantly increased the memory score in the retention test. 6. CNMSH and ChAL significantly attenuated the reduction of CA1 neurons, but insignificantly attenuated the reduction of CA1 thickness. 7. CNMSH and ChAL significantly attenuated the up-regulation of Bax expression in the CA1 of hippocampus. 8. CNMSH and ChAL significantly attenuated the up-regulation of cascapse-3 expression in the CA1 of hippocampus. 9. CNMSH and ChAL significantly attenuated the ${\beta}-amyloid$ accumulation in the CA1 of hippocampus. 10. CNMSH and ChAL significantly attenuated the up-regulation of APP expression in the CA1 of hippocampus. 11. CNMSH and ChAL significantly attenuated the up-regulation of BACE-1 expression in the CA1 of hippocampus. Conclusions : The results show that CNMSH attenuates neuronal apoptosis and ${\beta}-amyloid$ accumulation in the hippocampus and alleviates the impairment of learning and memory produced by chronic cerebral hypoperfusion. These results suggest that CNMSH may be a beneficial medicinal herb to treat cognitive impairment associated with neurodegenerative diseases.

• 대한족부족관절학회지
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• 제13권1호
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• pp.80-84
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• 2009

Purpose: The purpose of this article is to assess the efficacy of a bioabsorbable polylactide (PLA) plate and screw for treating injuries of ankle fractures. Materials and Methods: 24 patients who underwent an open reduction and internal fixation operation for ankle fractures from July 2005 to March 2007 were enrolled into the study. There were 15 men and 9 women. The average age of the patients was 44 years and the average follow-up period was 16 years and two months (16.2 months). All cases were divided into low grade fracture patient (11) who belongs in type A and B of Danis-Weber classification and high grade fracture patient (13) who belongs in type C1, C2 of Danis-Weber classification, and each groups were analyzed by clinical (Meyer score) and radiological finding at the time of their last follow-up evaluation. Results: The clinical results according to Meyer scoring system, showed that all patient with low grade fracture had good to excellent result, but only 54% of patient with high grade fracture had good to excellent result. According to Cedell's radiologic finding, there were 91% cases above fair in low grade fracture. But there were 62% of patient above fair result in high grade fracture, the reduction losses were seen in 38% of patient with high grade fracture. Conclusion: Bioabsorbable PLA plate and screw is good internal fixation device which doesn't have additional operation for removal of implant because of slow absorption within the human body. It showed sufficient strength for acquisition and maintenance of reduction in low grade fracture, but need attention to use because of many cases of reduction loss in high grade fracture. So, it seems to be safe and effective when used in heeling of low grade fracture under considering about type of fracture sufficiently.

• 핵의학기술
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• 제13권1호
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• pp.9-14
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• 2009

최근 영상 처리 기법의 발전으로 영상의 질은 저하시키지 않고 검사 소요시간을 단축시키는 방법들이 개발되고 있다. 특히 단층 촬영의 경우 영상 재구성 방법을 개선하여 영상의 질이 우수한 영상을 획득할 수 있게 되었다. Philips사의 PRECEDENCE 16 감마카메라를 이용해 보편적으로 시행하고 있는 분석법에 의한 FBP 방법과 반복법에 의한 Astonish, 3D OSEM 방법을 이용해 각각 영상을 재구성하여 정성적인 분석과 정량적인 분석을 통해 영상 획득시간을 다르게 한 영상간의 비교와, 동일한 시간으로 획득한 영상을 비교하여 영상의 질이 우수한 재구성 방법에 대해 연구 하였다. 정성적인 분석을 위해 blind test를 한 결과, 영상 획득시간에 따른 영상의 질은 거의 차이가 없는 것을 확인할 수 있었다. 또한 정량적인 분석을 통해서도 영상 획득시간에 따른 영상의 질은 통계적으로 유의한 차이가 없었다. 하지만 영상 획득시간이 동일한 영상을 재구성 방법에 따라 분석한 결과는 통계적으로 유의한 차이가 있음을 확인할 수 있었다. 영상의 질은 반복법을 이용하는 Astonish에 의해 재구성된 영상이 해상력이 좋고 임상적으로 진단적 정보를 제공하는데 우수한 영상으로 판단된다. 영상을 재구성하기 위한 소요시간이 길고 저장 공간의 부족 등으로 현재까지 많이 사용되지 않던 반복법에 의한 재구성 방법이 영상의 질은 향상시키고 검사시간은 단축 할 수 있는 방법이 될 수 있음을 확인하였다.

• 한국통신학회논문지
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• 제31권4C호
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• pp.331-340
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• 2006

이 논문에서는 다중경로 채널 환경에서 비동기식(Noncoherent) 초광대역(Ultra Wide Band) 무선통신 시스템의 고속 고신뢰 신호 동기획득을 위해, 저자들이 동기식(Coherent) 초광대역 시스템을 위해 제안하였던 TSS-LS (Two-Step Search scheme with Linear search based Second step). 기법을 비동기식 초광대역 시스템에 확장 적용하는 방안을 제안한다. 간단한 에너지 윈도우 뱅크를 사용하는 제안된 비동기식 TSS-LS 기법은 고속의 동기획득을 위해 두 단계의 서로 다른 문턱값과 탐색창을 적용하게 된다. 더욱이 다중경로 채널의 실효 지연 확산 범위에서의 시작 지점을 정확히 찾고 비동기식 초광대역 변복조와 연동했을 때 신뢰성 있는 비트오율(Bit Error Rate) 성능을 얻기 위해 두 번째 단계에서 선형 알고리즘을 적용한다. IEEE 802.15.3a의 다중경로 채널 모형을 이용한 모의실험 결과, 일반적인 탐색 기법보다 제안된 기법의 평균 동기획득 소요 시간이 큰 폭으로 단축됨을 확인할 수 있었다. 또한, 신호 동기획득 과정과 연동된 비트오율 성능 평가에서 신호대잡음비가 높을 때 이상적인 동기획득의 경우에 필적하는 매우 우수한 성능을 보임을 확인할 수 있었다.

• Current Optics and Photonics
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• 제5권4호
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• pp.421-430
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• 2021

The multifocal multiphoton microscopy (MMM) enables high-speed imaging by the concurrent scanning and detection of multiple foci generated by lenslet array or diffractive optical element. The MMM system mainly suffers from crosstalk generated by scattered emission photons that form ghost images among adjacent channels. The ghost image which is a duplicate of the image acquired in sub-images significantly degrades overall image quality. To eliminate the ghost image, the photon reassignment method was established using maximum likelihood estimation. However, this post-processing method generally takes a longer time than image acquisition. In this regard, we propose a novel strategy for rapid noise reduction in the MMM system based upon Monte-Carlo (MC) simulation. Ballistic signal, scattering signal, and scattering noise of each channel are quantified in terms of photon distribution launched in tissue model based on MC simulation. From the analysis of photon distribution, we successfully eliminated the ghost images in the MMM sub-images. If the priori MC simulation under a certain optical condition is established at once, our simple, but robust post-processing technique will continuously provide the noise-reduced images, while significantly reducing the computational cost.

• 디지털산업정보학회논문지
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• 제6권3호
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• pp.19-29
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• 2010

A marketing model is changed from a customer acquisition to customer retention and it is being moved to a way that enhances the quality of customer interaction to add value to our customers. Such personalization is emerging from this background. The Web site is accelerate the adoption of a personalization, and in contrast to the rapid growth of data, quantitative analytical experience is required. For the automated analysis of large amounts of data and the results must be passed in real time of personalization has been interested in technical problems. A recommendation algorithm is an algorithm for the implementation of personalization, which predict whether the customer preferences and purchasing using the database with new customers interested or likely to purchase. As recommended number of users increases, the algorithm increases recommendation time is the problem. In this paper, to solve this problem, a recommendation system based on clustering and dimensionality reduction is proposed. First, clusters customers with such an orientation, then shrink the dimensions of the relationship between customers to low dimensional space. Because finding neighbors for recommendations is performed at low dimensional space, the computation time is greatly reduced.

• 전기학회논문지
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• 제57권3호
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• pp.507-513
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• 2008

In this study, we develope an ambulatory ECG acquisition system by implementing a patch-style and wireless electrode. To alleviate the inherent noisy characteristics of the mobile signal, we apply a matched filter and concurrently detect R-peak values. Moreover, the measure for resolving shape distance is computed to estimate the relative similarity between two ECG signals and to decide whether the abnormal characteristics in ECG exist or not.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 가을 학술발표논문집 Vol.34 No.2 (D)
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• pp.394-397
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• 2007

This study aims to examine its problems, control and handling by analyzing Barcode System, one of the Material Handling which are currently often used in medical Industry, and improve the present unnecessary orders and handling to improve material control and handling related to medical supplies by applying these days appearing RFID(Radio Frequency IDentification) System to material handling system. By this, it is expected that reduction of unnecessary inventory and exact information acquisition of goods will be possible. And by this, this study also aims to build and use closer cooperation system between hospitals and material system reducing time needed for material handling by controlling material flow effectively by taking advantage of them effectively.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2009년도 춘계학술대회 논문집 특별세미나,특별/일반세션
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• pp.351-355
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• 2009

There are two types of controller between railway and train. those are the Continuous Message Controller and the Intermittent Message Controller using for KHSR. The conventional Intermittent Message Controller board used a variable resister for setting the phase, but the variable resister affected some environmental facts, such as temperature, humidity, and vibration, etc. And It is requirement of reduction message processing time for speed-up operation in Next-Generation High-Speed Rail. This study suggests how to solve the problem described above. Using FPGA is quite profitable. It's easy to use and maintain, flexible with the New algorithm to fix up the problem.