• Journal of Aerospace System Engineering
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• v.17 no.1
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• pp.16-23
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• 2023

The aircraft fuel system performs a number of functions such as supplying fuel, transferring fuel between fuel tanks, and measuring the amount of residual fuel in each fuel tank. Since it is a direct cause of fire hazard in crash incident, it is a must to improve survivability of crew members by designing the airframe to tolerate expected crash impact. The civil aviation authority requires intensive verification of the fuel system design to determine precise application of the airworthiness requirement. Research activity on airworthiness certification criteria and verification scheme is still insufficient, although it has a significant importance. In this paper, as part of a study to improve flight safety by developing guidelines for demonstrating fuel system crash resistance, analysis results of fuel system crash-related airworthiness certification standards, verification scheme, and cases study applicable to military rotorcraft have been reviewed.

• Fashion & Textile Research Journal
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• v.24 no.6
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• pp.694-706
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• 2022

This study focusses on the development of a motion-sensing smart leggings prototype with the help of a module that monitors motion using a fiber-type stretch sensor. Additionally, it acquires data on Electrocardiogram (ECG), respiration, and body temperature signals, for the development of smart clothing used in online exercise coaching and customized healthcare systems. The research process was conducted in the following order: 1) Fabrication of a fiber-type elastic strain sensor for motion monitoring, 2) Positioning and attaching the sensor, 3) Pattern development and three-dimensional (3D) design, 4) Prototyping 5) Wearability test, and 6) Expert evaluation. The 3D design method was used to develop an aesthetic design, and for sensing accurate signal acquisition functions, wearability tests, and expert evaluation. As a result, first, the selection or manufacturing of an appropriate sensor for the function is of utmost importance. Second, the selection and attachment method of a location that can maximize the function of the sensor without interfering with any activity should be studied. Third, the signal line selection and connection method should be considered, and fourth, the aesthetic design should be reflected along with functional verification. In addition, the selection of an appropriate material is important, and tests for washability and durability must be made. This study presented a manufacturing method to improve the functionality and design of smart clothing, through the process of developing a prototype of motion-sensing smart leggings.

• The Journal of the Convergence on Culture Technology
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• v.10 no.4
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• pp.47-63
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• 2024

The purpose of this study was to be arranged as part of the phased study to examine a mutual ecosystem between creators and viewers by being interested in individual media environments which have led big changes as a tool of the new concept for obtaining information as well as aspects of information acquisition and availability and exploring activity areas of a minority of media creators. Especially, the purpose is to take note of desires and demands of users of YouTube travel content services which have rapidly grown due to a pike in recent users' interest, examine a study on a relationship among perception of information attributes of Youtube travel content, information satisfaction, and behavior intention and the vividness' moderating effects to form in their relationships, and prove the process to form these relationships through specific data. In conclusion, implications which can be inferred based on the results of the study and suggestions for further studies of the future were presented.

• The Korean Journal of Nuclear Medicine Technology
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• v.17 no.2
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• pp.90-94
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• 2013

Purpose: In the PET/CT images, various artifacts cause degradation of the quantitative assessment. Most hotspot generated by radiopharmaceutical injection errors cause an artifact and degrade the quality of the images as well as the accuracy of the quantitative evaluation. The purpose of this study is to assess effectiveness of the elimination of the hotspot at the injection sites using shifting the center of DFOV (Display Field of View, DFOV) method and evaluate the quantitative evaluation of result. Materials and Methods: GE Discovery STE 16 (GE Healthcare, Milwaukee, USA) and 1994 NEMA phantom were used for imaging acquisition. Phantom was filled with 0.005 MBq/mL of $^{18}F-FDG$. A hotspot was artificially placed on the outside of the phantom. The ratio of hotspot area activity to background area activity was regulated as 200:1. After image acquisition with routine protocol, all of the images were reconstructed using the shifting the center of DFOV method that wasn't overlapped with hotspot. Those images obtained before and after applying the shifting reconstruction method were compared. ROIs (Region Of Interests) were set in the hotspot areas, meanSUVs and standard deviations were calculated. Percentage differences were calculated with those meanSUVs and standard deviations. The evaluation on the effects of the shifting reconstruction method was done by comparison of the meanSUVs and the standard deviations, which were calculated for background areas unaffected by hotspot. Results: In the areas of unaffected by hotspot, meanSUVs before and after applying the shifting of center of DFOV method were $0.67{\pm}0.06g/mL$ and $0.65{\pm}0.06g/mL$, respectively. In the artifact areas affected by hotspot, meanSUVs before and after applying the shifting of center of DFOV method were $0.32{\pm}0.08g/mL$ and $0.56{\pm}0.12g/mL$, respectively. The percentage differences of the area adjacent to the hotspot and the area distant from the hotspot were 65.3% and 97.4%, respectively. Conclusion: In the PET/CT images, meanSUV was improved by 32.1% when the effect of artifact was removed with application of the shifting the center of DFOV methode. In other areas unaffected by artifacts, meanSUVs were not significantly different after applying DFOV center shift method. As shown in the result, adverse effects of hotspot made by swelling in the injection site can be reduced by applying DFOV center shift method. Therefore, DFOV center shift method can be applied for the more precise quantitative evaluation, and contribute to the increase of the diagnostic value of the images.

• The Korean Journal of Blood Transfusion
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• v.23 no.2
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• pp.115-126
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• 2012

Background: Umbilical cord (UC) is a promising source of mesenchymal stromal cells (MSCs). We compared the characteristics of MSCs from cryopreserved UC with those from fresh tissues, and demonstrated the possibility of UC cryopreservation for acquisition of MSCs from cryopreserved UC. Methods: Each UC was sliced into two types ($1{\sim}2mm^3$ vs. 0.5 cm), and cryopreserved in liquid nitrogen using different media (autologous cord blood plasma, aCBP vs. RPMI 1640). A fresh aliquot of $1{\sim}2mm^3$-sized UC was used as control tissue. After one week, the cryopreserved tissues were thawed and cultured. For the 0.5 cm UC, a slicing step into $1{\sim}2mm^3$ was needed. Cell count, viability, proliferative activity, and surface antigens were determined from harvested MSCs. Several growth factors (EGF, IGF-1, PDGF, TGF-${\beta}$, bFGF, and VEGF), were measured from the culture supernatant. Results: Eleven UC were enrolled in the study. Efficiencies of obtaining MSCs were higher in cryopreserved UC using RPMI 1640, compared with use of aCBP; the same result was observed for 0.5 cm sized UC, compared with $1{\sim}2mm^3$ sized UC. No difference in proliferative activity was observed between MSCs from fresh and cryopreserved UC. The amount of growth factors in culture supernatant using RPMI 1640 was larger than that of fresh tissues. Conclusion: We obtained growth factors from the supernatant as well as MSCs from cryopreserved UC. As with a cord blood bank, in the future, cryopreservation of UC for acquisition of both MSCs and growth factors would be possible in a time of need.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.4
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• pp.516-523
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• 2015

This study investigated the antimutagenic and anticancer effects of Platycodon grandiflorum extract (PGE) and its fractions against carcinogenic N-nitrosodimethylamine (NDMA) and genotoxicity. The Ames Salmonella mutagenicity test employing histidine mutants of Salmonella Typhimurium TA98 and TA100 was used to examine the mutagenicity of PGE and its fractions. Bacterial reversion assay with S. Typhimurium TA98 and TA100 did not show a significantly increased number of revertant colonies. The same test was used to examine the ability of PGE and its fractions to prevent acquisition of N-methyl-N'-nitro-N-nitrosoguanidine- and 4-introquino-line-1-oxide-induced mutations. PGE and its fractions inhibited mutagenesis in a dose-dependent manner. Among the fractions, ethyl acetate fraction from PGE (PGEA) exhibited a higher antimutagenic effect than other fractions. PGE and its fractions suppressed the growth of cancer cell lines, including human cervical adenocarcinoma, human hepatocellular carcinoma, human breast adenocarcinoma, human lung carcinoma, and transformed primary human embryonic kidney cells. In addition, we evaluated the antitumor activity of PGEA and its fractions in sacorma-180 solid tumor-bearing mice. In vivo anticancer activity results showed that PGE and its fractions could more effectively suppress tumor growth than the control. PGEA showed higher in vitro and in vivo anticancer effects than PGE and other fractions, and PGEA inhibited NDMA formation. Thus, we showed that PGEA has antimutagenic and anticancer activities, making it a candidate anticancer material under these experimental conditions.

• ALGAE
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• v.31 no.1
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• pp.73-84
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• 2016

Marine organisms are frequently used to be harmful and have lower side effects than synthetic drugs. The cognitive improving efficacy of gamma aminobutyric acid-enriched fermented Saccharina japonica (FSJ) on the memory deficient rats, which were induced by trimethyltin chloride (TMT), was investigated by assessing the Morris water maze test and by performing choline acetyltransferase (ChAT), cAMP response element binding protein (CREB), and brain derived neurotrophic factor (BDNF) immunohistochemistry. The neurite outgrowth of Neuro2a cells was assessed in order to examine the underlying mechanisms of the memory enhancing effects of FSJ. Treatment with FSJ tended to shorten the latency to find the platform in the acquisition test of the Morris water maze at the second and fourth day compared to the control group. In the probe trial, the FSJ treated group increased time spent in the target quadrant, compared to that of the control group. Consistent with the behavioral data, these treatments recovered the loss of ChAT, CREB, and BDNF immunepositive neurons in the hippocampus produced by TMT. Treatment with FSJ markedly stimulated neurite outgrowth of the Neuro2a cells as compared to that of the controls. These findings demonstrate that FSJ may be useful for improving the cognitive function via regulation of neurotrophic marker enzyme activity.

• The Korean Journal of Nuclear Medicine
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• v.1 no.2
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• pp.61-74
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• 1967

In order to confirm whether acquired immunity or resistance can be developed by the repeated hookworm infections, the 150 mature actively moving filariform ancylostoma duodenale larvae obtained from the severe hookworm anemia patients were orally given to 8 healthy volunteers in three divided doses, 50 in each, at 5 day interval. Also the hematological changes as well as several ferrokinetics using $^{59}Fe$ were done and were compared with 10 controls. The clinical symptoms and signs were checked every day for the first 3 weeks and then twice weekly until the end of the experiment. The appearance of the ova in the stool was examined by the formalin ether method and the ova was counted by the Stoll's method. The following laboratory tests were done: 1) Red blood cell count, venous blood hematocrit(micromethod), hemoglobin count (cyanomethemoglobin method) were checked every 5 to 7 day interval. 2) Plasma iron concentration (Barkan's modified method) was determined every 2 to 3 week interval. 3) Radioisotope studies: a) Ferrokinetics: Huff et al and Bothwell's method were applied. Erythropoietic Index (% of normal)=$\frac{Subject's\;turnover/100ml\;whole\;blood{\times}100}{Average\;normal\;turnover/100ml\;whole\;blood}$ of the gastrointestinal absorption of iron: Radioiron($^{59}Fe$) balance b) Quantitative measurement method was applied. c) Determination of the plasma erythropoietin activity: Fried's method was applied. Following were the results: 1) The serum iron level was lower. The red cell volume was decreased, but with relative increase of plasma volume. 2) The plasma iron disappearance time was accelerated and the plasma iron turnover rate was decreased. The red cell iron turnover rate was markedly increased, while all of the red cell iron concentration, circulating red cell iron. plasma iron pool were decreased. The daily iron pool turnover and red cell renewal rate were increased. 3) The erythropoietic index, erythropoietin activity and intestinal absorption of iron($^{59}Fe$) were markedly increased. 4) The infectivity was $9.8{\pm}1.31%$ which was lower than that observed in the single infection. 5) From these observations, it is concluded that the hookworm anemia is essentially iron deficieny in its origin and some immunity acquisition is possible with repeated infections.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.11
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• pp.183-190
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• 2012

Conventional physical activity monitoring systems, which use accelerometers, global positioning system (GPS), heartbeats, or body temperature information, showed limited performances due to their own restrictions on measurement environment and measurable activity types. To overcome these limitations, we developed a portable exercise analysis system that can analyze aerobic exercises as well as isotonic exercises. For bioelectric signal acquisition during exercise, waist belt with two body contact electrodes was used. For exercise analysis, the measured signals were firstly divided into two signal groups with different frequency ranges which can represent respiration related signal and muscular motion related signal, respectively. After then, power values, differential of power values, and median frequency values were selected for feature values. Selected features were used as inputs of support vector machine (SVM) to classify the exercise types. For verification of statistical significance, ANOVA and multiple comparison test were performed. The experimental results showed 100% accuracy for classification of aerobic exercise and isotonic resistance exercise. Also, classification of aerobic exercise, isotonic resistance exercise, and hybrid types of exercise revealed 92.7% of accuracy.

• Journal of Korean Academy of Nursing
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• v.29 no.1
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• pp.139-149
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• 1999

It is very important to establish precisely the historical phases of nursing. We nurses should try to acquire the central social position in the health management system in the near the future, the 21st Century. Therefore my treatise aims to orient the desirable phases of the history of nursing through the feministic survey of the history of nursing from the post medieval epoche to the modern epoche. During the time of the renaissance which gave morning light to the modern epoche, the antique Athenian thinking of sex was again revived. Athenian excluded the women from the public and autonomous regions. All the medical activity, once dominated by the women, was misfortunately regarded as superstition acted by witches. Accordingly, the nursing women were to hunted as witches. In short, in the early modern epoche, women began to be excluded from the history of medical activities. In the middle modern epoche characterized by the enlightenment movement and early capital economic system, capitalistic patriarchal system began to be formed by change in the economic system. The status of women began to be greatly dropped below by the social distinction of the private dimension of home and the Public dimension of job. The woman was deprived of even the occasion to get the official license of medicine and medical institutions were handed to the state or the powerful and rich merchants. Accordingly, nursing acted mainly in the nunnery as the total approach to the patients was destructed wholly and transformed into the means of earning the money. Therefore unprepared low class -women began to engage in nursing only for the money. From then on, nursing activity was tunneled through the dark age for 200 years. In the late modern epoche characterized by the contrast of the accumulated vast capital by industrialization and vast poverty of the peoples, feminism began to float over the surface for the acquisition of equality of men and women from England. A feminist, Nightingale insisted that the women as nurses should be responsible for the healthy life of man. She tried the professional nursing education for women. Accordingly she not only contributed to the intellectual progress of women but also inspired in women the consciousness of the professional job. She tried to realize the ideal of at-that-time-feminists by engaging in nursing all through life. She really paved the road to contemporary nursing. In the near the future, I will write to describe how the late modern epoche nursing has fallen into the dilemma through the 1st and 2nd world wars and matured capitalism and to consider contemporary nursing with the status of women. All these papers aim to give proper recognition of nursing and right orientation of the future 21st Century nursing.