• 식물분류학회지
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• 제47권2호
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• pp.154-160
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• 2017

식물명 창포, 석창포를 비롯하여 수창포와 계손 등은 우리나라 옛날 고전에서부터 혼란스럽게 혼용되어 왔으며 오늘날에도 마찬가지이다. 따라서 본 연구에서는 이들의 정확한 실체를 규명하기 위해서 중국 고전과 우리나라 고전, 그리고 최근의 중국과 우리나라 식물지를 비교 검토했다. 중국에서는 창포와 석창포는 잎에 잎맥이 뚜렷하게 발달하는 Acorus calamus를 지칭하는 이름으로 사용되어 왔고, 수창포와 계손은 잎에 잎맥이 뚜렷하지 않은 A. gramineus를 지칭하는 이름으로 사용되어 왔음이 확인되었다. 그러나 우리나라에서는 석창포와 계손은 A. gramineus로, 수창포와 창포는 A. calamus를 지칭했으나, 이름들이 혼용되어 온 것으로 확인되었다. 혼용에 따른 혼란을 피하기 위해 계손과 석창포라는 이름을 사용하지 않고 A. calamus는 창포로, A. gramineus는 수창포로 부를 것으로 제안한다. 그리고 생물다양성협약에 대응하기 위해서는 한자로 표기된 식물명의 정확한 분류학적 실체를 규명해야 하며, 동시에 예부터 사용해왔던 한글로 표기된 식물명에 대한 연구가 필요함을 덧붙인다.

• 생약학회지
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• 제13권2호
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• pp.62-69
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• 1982

Fiftythree species(35 families and 52 genera)of Korean medicinal plants which have been frequently used in oriental herb prescriptions or have been used as folklorics were evaluated on their short term acute toxicity and potential antitumor activities against P-388 murine lymphocytic leukemia model in vivo. Among these plants Acorus gramineus (Araceae), Agrimonia pilosa (Rosaceae), Aralia elata (Araliaceae), Dryopteris crassirhizoma (Aspidiaceae), Syringa reticulata (Oleaceae) and Calystegia japonica (Convolvulaceae) exhibited potent acute toxicity resulting from severe weight loss and death. Agrimonia pilosa (Rosaceae) showed about 33% of increased life span in comparison with that of control group mouse, but others exhibited no significant antitumor activities.

• 한국식품저장유통학회지
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• 제20권2호
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• pp.272-277
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• 2013

우리의 고유 음식인 삼계탕에 인지기능 향상 및 뇌질환 예방 효과를 가지고 있는 도라지, 더덕, 석창포를 부재료로 이용하여 한방 삼계탕의 제조를 위한 최적 혼합 비율을 설정하고자 한약재 부재료의 혼합 비율에 따른 품질 특성과 관능적 특성을 조사하였다. 삼계탕 국물의 pH는 석창포의 함량이 가장 많은 한약재 조합인 S2는 4.57로 가장 낮은 값을 보였으며, 당도는 더덕의 함량이 가장 높은 S3에서 $3.87^{\circ}Brix$로 다른 시료에 비해 유의적으로 높은 함량을 보였다. 명도와 황색도는 더덕의 함량이 가장 많은 한약재 조합인 S3에서 가장 낮은 값을 보였으며, 반면에 적색도는 더덕 혼합 비율이 증가함에 따라 a값도 증가하는 경향을 보였다. 관능검사 결과 향미는 도라지의 함량이 가장 많은 시료에서 가장 높은 기호도를 보였으나, 이를 제외한 색, 맛, 전체적인 기호도는 더덕의 함량이 가장 높은 한약재 혼합 비율에서 가장 높은 점수를 보였다. 본 연구 결과, 한방 삼계탕 제조를 위한 한약재의 혼합 비율은 도라지, 석창포, 삽주, 감초, 대추는 각 4 g, 오미자 6 g, 그리고 더덕 12 g이 가장 적합하다고 판단된다.

• 동의생리병리학회지
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• 제28권3호
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• pp.317-321
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• 2014

Amyloid-${\beta}$ protein ($A{\beta}$) is a pathological component of Alzheimer's disease (AD) by participating in the senile plaque formation in the patient's brain. Although the exact mechanism of $A{\beta}$ toxicity is not fully elucidated, it is considered to be closely related to its fibrillation process. For prevention of AD, recent studies have suggested various small molecules which inhibit $A{\beta}$ fibrillation. In this report, ${\beta}$-asarone found in acorus plant has been investigated as an anti-amyloid molecule. ${\beta}$-Asarone was demonstrated to prevent in vitro fibrillation of $A{\beta}$ by inducing the oligomer formation that obviously decreased cytotoxicity. Therefore, ${\beta}$-asarone could be suggested as an inhibitory agent of $A{\beta}$ fibrillation and toxicity, which would help us not only to understand underlying principle of amyloidogenesis mechanism but also to develop a controlling strategy toward AD.

• 한국자원식물학회:학술대회논문집
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• 한국자원식물학회 2020년도 춘계학술대회
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• pp.67-67
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• 2020

Though there is an on-going need for the diversity of ornamental plants for in-door environment, their growth and stress adaptability in comparatively low light intensity condition require further studies for implementation. Here investigates the growth and chlorophyll fluorescence parameters of Farfugium japonicum (L.) Kitam, Liriope muscari (Decne.) L.H.Bailey and Acorus gramineus Aiton under several light intensities which were based on common in-door environment. The growth measurement of the plants included the quantity, length, width and SPAD value of the leaves. Calculated values of Fm/Fo, Fv/Fm, Pi_Abs, ETo/RC and DIo/RC were used as the parameters of the chlorophyll fluorescence under 10, 50, 100 and 200 PPFD (μmol·m^-2·s^-1) light intensities. In-door plants group was put in a closed room allowing no other light sources for 10 weeks and the control group was put in glass-greenhouse for the same period. The overall in-door growth of L. muscari was not significantly different in all light intensities compared to the control group and even showed the higher SPAD values. Also, an increasing tendency of Pi_Abs value under 10 to 100 PPFD was observed implying that L.muscari could adapt well to in-door environment. Measurement of A. gramineus growth mostly showed the highest values in the control group especially in the number of the leaves. Nevertheless, chlorophyll fluorescence parameters showed no significant value difference between in-door and the control groups and thus, A. gramineus might have possibility of successful adaptation to in-door environment. F. japonicum showed deficient growth in plant height and leaf length compared to the control but, it seemed to be able to sustain ornamental value under in-door light intensities. Furthermore, Pi_Abs and DIo/RC values were increased under in-door light conditions suggesting potential adaptability of F. japonicum.

• Natural Product Sciences
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• 제15권4호
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• pp.198-202
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• 2009

Based on the use of Acorus gramineus SOLAND (AG) for the treatment of stroke in traditional Korean medicine, the present study was carried out to evaluate neuroprotective effects of ${\alpha}$-asarone after transient global cerebral ischemia using rat 4-vessel occlusion (4VO) model in rats. ${\alpha}$-Asarone (5 mg/kg) administered intraperitoneally significantly protected CA1 neurons against 10 min transient forebrain ischemia as demonstrated by measuring the density of neuronal cells stained with Cresyl violet. ${\alpha}$-Asarone significantly reduced hippocampal neuronal cell death by 85.2% where as its isolated single compounds from AG compared with a vehicle-treated group.

• Archives of Pharmacal Research
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• 제20권4호
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• pp.375-378
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• 1997

The Chongmyungtang (CMT; the combination of Acorus gramineus, polygala tenuifolia and Poria cocos) has been recognized to possess the preventive effect against several neurologic disorders in human. In this study, we examined the effect of CMT on the three parameters associated with kainic acid (KA)-induced neurotoxicities; seizure/mortality, increased fos-related antigen (FRA) and glial fibrillary acidic protein (GFAP) expression. KA induced vigorous convulsions lasting 4-6 hr. Pretreatments with CMT before KA injection significantly reduced the seizure intensity as well as the mortality. CMT pretreatments also attenuated the KA-induced increase in FRA/GFAP expression in the hippocampus. These results suggest that CMT has a neuroprotective effect against KA-induced neurotoxicities.

• 생명과학회지
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• 제10권4호
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• pp.374-379
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• 2000

This study was attempted to evaluate an agonistic activity to benzodiazepine receptor of several medicinal pants, which have been used as sedatives in oriental medicine. The activities of the methanol extracts of composite preparation of oriental drugs were compared with those of the simple drugs, furthermore, the active fraction was found out from the simple preparation. Inhibitory effects of composite preparations, Cyperus rotundus/Acorus gramineus, Thuja orientalis/Euphoria longan, Thuja orientalis/Albizzia julibrissin, on the binding of ${[^3H]}$Ro15-1788, a selective benszodiazepine receptor antagonist to benzodiazepine receptor of rat cortices, were observed to be lower than those of corresponding simple preparations. These unexpected results suggest that some components of the composite druge may rather act as an obstacle, not to show the sinergistic effect. The methanol extracts of Cyperus rotundus having the highest activity were fractionated using polar and nonpolar solvents to give ethylacetate and hexane fractions, respectively. The ethylacetate fraction containing relatively polar components exhibited much higher activity than the hexane fraction, which consiste of nonpolar agonist, binding to benzodiazepine receptor. However, in the presence of GABA, this fraction inhibited ${[^3H]}$flunitrazepan binding, and these positive GABA shift supported the strong possibility of agonistic activity to benzodiazepine receptro. As a result, it may be concluded that the substance or substances with neurochemical properties as a benzodiazepine receptor agonist may contribute to the sedative property of Cyperus rotundus.

• 생약학회지
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• 제40권1호
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• pp.41-45
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• 2009

Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzhemier's disease. Neuropathologically, PD is characterized by the selective loss of dopaminergic neurons. The neuronal toxicity of cytosolic excess dopamine (DA) has been described in many studies using several cell lines. In dopaminergic neurons, cytosolic excess DA is easily oxidized via monoamine oxidase (MAO)-B, tyrosinase or by auto-oxidation to produce neurotoxic metabolites such as DA quinone. So, in the present study, we induced cell death by treatment of DA ($600{\mu}M$) in human neuroblastoma SH-SY5Y cell which was treated samples before 24 hr, and cell viability was measured by fluorescence activated cell sorter (FACs) analysis. Of those tested, the extracts of Poria cocos (赤茯笭)(whole), Gastrodia elata (rhizomes), Eucommia ulmoides (炒)(barks), Syneilesis palmata (whole), Acorus gramineus (rhizomes), Ligustrum japonicum (leaves) showed neuroprotective effects in dose dependent manner.

• 한국환경생태학회지
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• 제16권3호
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• pp.296-308
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• 2002

천관산 지역에서 채집된 표본을 동정한 결과, 관속식물 전체 종수는 117과 366속 519종 76변종 4품종으로 총 599종류로 나타났다. 본 지역은 봉의꼬리, 족제비고사리, 비자나무, 개비자나무, 참식나무, 붉가시나무, 송악, 팔손이, 동백나무, 사스레피나무, 차나무, 석창포, 이대 및 조릿대 등의 상록성 수종과 소사나무, 푸조나무, 상산이나 실고사리 등 낙엽성 난대성 식물이 혼재하고 있다. 구실사리, 히어리, 노각나무, 족도리풀, 노랑 제비꽃, 끈끈이주걱 등이 분포하는 것도 특기할 만하다. 환경부에서 지정한 평가단위별 특정식물은 5 등급이 1 분류군, 4등급은 1 분류군, 3 등급은 5 분류군, 2등급이 1 분류군 그리고 1등급이 37분류군으로 총 45 분류군으로 확인되었다.