• 한국환경보건학회지
• /
• 제17권2호
• /
• pp.121-126
• /
• 1991

To clarify a cause of increased serum level of acid phosphatase in CCl$_{4}$-treated rats, the acid phosphatase activity of liver was compared with that serum. Concomitantly, the serum and liver acid phosphatase activity of CCl$_{4}$-treated rats were compared with that of CCl$_{4}$-treated rats pretreated with prednisolone or actinomycin D. In CCl$_{4}$-treated rats, the activity of serum acid phosphatase was significiantly increased whereas that of liver acid phosphatase was rather slightly decreased. the pretreatment of prednisolone led to the decreased activity of serum and liver acid phosphatase in CCl$_{4}$-treated rats. But the pretreatment of actinomycin D rather increased the activity of liver and serum enzyme. In conclusion, it is likely the increased activity of serum acid phosphatase is based on the excess leaking of acid phosphatase into blood by the increased membrane permeability of both liver cell and lysosome in it.

• 한국식생활문화학회지
• /
• 제13권3호
• /
• pp.191-196
• /
• 1998

LL면 제조에 있어서 유기산의 첨가가 LL면의 색상, 조직감, 저장 안정성과 관능적 특성에 미치는 영향을 검토하기 위하여 유기산의 종류를 달리한 다음 밀가루에 0.2%를 첨가하여 LL면을 제조한 뒤 조리시험, 면의 조직감 특성, 미생물 측정 및 관능검사를 평가하였다. Hunter L값은 dl-malic acid를 첨가하여 제조한 LL면이 70.49로 가장 높게 나타났으며, Hunter a, b값은 모든 처리구가 유사하게 측정되었다. 층밀림 압출력은 dl-malic acid를 첨가하여 제조한 처리구 B가 20.55(kgf)로 가장 높게 나타났으며. 젖산을 첨가한 처리구 A가 가장 작은 수치인 18.05(kgf)로 측정되었다. 경도도 dl-malic acid를 첨가하여 처리구 B가 25.43(kgf)으로 가장 높게 나타났으며 젖산을 첨가한 처리구 A는 21.21(kgf)으로 측정되었으나 처리구간에 큰 차이는 없었다. dl-malic acid를 첨가한 처리구 B와 dl-사과산과 초산을 1:1로 첨가한 처리구 D를 첨가하여 제조한 LL면의 무게 증가는 다른 처리구보다 낮게 나타났다. 반면에 부피 증가는 오히려 높게 나타나 조직이 다소 치밀함을 알 수 있었다. 용출양의 변화는 모든 처리구가 $16{\sim}25%$의 범위를 나타냈으며 dl-malic acid를 첨가한 처리구 B와 dl-사과산과 초산을 1:1로 첨가한 처리구 D를 첨가하여 제조한 LL면이 감소하는 경향을 보였다. 미생물수는 dl-malic acid를 첨가한 처리구 B와 dl-사과산과 초산을 1:1로 첨가한 처리구 D를 첨가하여 제조한 L면이 $30^{\circ}C$에서 5개월 이상 저장에도 검출되지 않았으나 control를 포함하여 젖산을 첨가한 처리구 A와 초산을 첨가한 처리구 C는 저장 1개월 이후부터 증가하는 경향을 보였다. 관능검사 결과는 dl-malic acid를 첨가한 처리구 B와 dl-사과산과 초산을 1:1로 첨가한 처리구 D를 첨가하여 제조한 LL면이 4.3 및 4.0으로 젖산을 첨가한 처리구 A와 초산을 첨가한 처리구 C의 3.1, 3.2보다 좋은 점수를 얻었다.

• 한방안이비인후피부과학회지
• /
• 제29권3호
• /
• pp.150-158
• /
• 2016

Objectives : We want to know the effect of Gyejakjimo-tang in mice model of acute pain.Methods : We investigated writhing reflex in mice with acetic acid-induced abdominal pain using mice, we observed c-Fos protien expression by immunohistochemistry dyeing method in the paraventricular nucleus(PVN) and supraoptic nucleus(SON) of the hypothalamus.Results : All of Gyejakjimo-tang treated group suppressed acetic acid-induced writhing response as acetic acid injuction group, but in 100㎎/㎏ Gyejakjimo-tang treated group and 200㎎/㎏ Gyejakjimo-tang treated groups represernted significance. All of Gyejakjimo-tang treated groups(50, 100 and 200㎎/㎏ Gyejakjimo-tang-treated group), Fos-positive cells in PNV significantly decreased as acetic acid injuction group, and All of Gyejakjimo-tang-treated groups Fos-positive cells in SON significantly decreased as acetic acid injuction group.Conclusions : The present results showed that the mice pre-treated with the aqueous extract of Gyejakjimo-tang showed analgesic effect on acetic acid-induced abdominal pain.

• 한국축산식품학회지
• /
• 제22권2호
• /
• pp.115-121
• /
• 2002

본 연구는 초음파 처리시간이 튀김 계육의 품질 및 기호성에 미치는 영향을 검토하기 위하여 실시하였다. 수분함량의 경우 가슴육 및 다리육 모두 U-10 처리구가 대조구보다 낮았으며, 단백질 함량은 대조구와 초음파 처리구 사이에 차이가 없었다. 지방함량은 초음파 처리시간이 길어질수록 높아졌다. 튀김감량은 초음파 처리구가 대조구보다 낮았으며, 보수력은 초음파 처리시간이 길어질수록 대조구보다 높아지는 경향이었다. 그리고 물리적인 조직감은 대조구와 초음파처리구 사이에 현저한 차이가 없었다. L*(명도)값은 대조구와 초음파 처리구 사이에 차이가 없었으나, 가슴육이 다리육보다 높았다. 그리고 a*(적색도)값은 초음파처리에 의한 영향은 없었으나 다리육이 가슴육보다 높았다. 구성아미노산은 glutamic acid, aspartic acid, lysine, leucine 및 arginine이 많이 함유되어 있었다. 지방산 조성은 oleic acid와 linoleic acid가 약 60% 이상을 차지하였다. 그리고 맛, 조직감, 다즙성 및 전체적인 기호성은 초음파 처리시간에 따라 향상되었다.

• BMB Reports
• /
• 제29권4호
• /
• pp.343-352
• /
• 1996

The biosynthesis of phospholipid and the composition of fatty acid were analyzed in mitochondria isolated from Chlorella ellipsoidea treated with carbon sources (glucose, sucrose, raffinose) during the culture. The growth of Chlorella and total lipid contents in mitochondria treated with various carbon sources was increased to compare with the control. When Chlorella mitochondria was treated with various carbon sources, four kinds of phospholipid were increased predominantly. The major fatty acids utilized for the biosynthesis of the phospholipid were analyzed linoleic acid (average 25.18%) and stearic acid (average 10.52%) in the control. But, it was shown that the major fatty acids in Chlorella mitochondria treated with glucose were stearic acid (average 30.93%), palmitic acid (average 17.47%) and stearic acid (average 20.31%), linoleic acid (average 16.68%) in sucrose treatment and oleic acid (average 17.17%), palmitic acid (average 15.64%) in raffinose treatment.

• 한국식품영양과학회지
• /
• 제26권6호
• /
• pp.1068-1076
• /
• 1997

This study was carried out to elucidate the utility of fusant for shortening the ripening time of imitation processed cheese. L. bulgaricus exhibited the highest protease and lactase activity and L. helveticus revealed the highest lipase activity. Fusant was shown to be high in the activity of protease and lactase. The total volatile free fatty acid produced by the cheese treated with L. helveticus was markedly increased after four ripening days and was gently increased after nine ripening days. However, L. bulgaricus significantly increased the total volatile free fatty acid between four and nine ripening days. In the case of fusant, the amount of total volatile free fatty acid was observed to increase at a constant rate relative to the ripening time. In free fatty acid production at different ripening times, L. bulfaricus generated caproic acid and caprilic acid abundantly while it produced a poor quantity of capric acid, lauric acid, and myristic acid. In the cheese sample treated with L. helveticus, the amount of caproic acid and capylic acid was on increase as the ripening time increased. The amount of caproic acid and caprylic acid produced by fusant was less than that produced by the other two starters. In the panel sensory evaluation, the flavor intensity and preference increased as the ripening time increased. The cheese sample treated with fusant showed the highest flavor intensity at 7 days, whereas cheese treated with L. helveticus exhibited the highest flavor intensity at 15 or 30 days. The cheese treated with L. helveticus showed the highest preference at 7 days, but cheese treated with fusant exhibited the highest preference at 30 days.

• Bulletin of the Korean Chemical Society
• /
• 제31권6호
• /
• pp.1596-1600
• /
• 2010

Surface functionalization of multi-walled carbon nanotubes (MWNTs) was carried out by means of acid treatment. The presence of oxygen functional groups on the surface of acid-treated MWNTs was confirmed with the aid of Fourier transform infrared spectroscopy and X-ray spectroscopy. In addition, carboxylic groups generally formed on the surface of acid-treated MWNTs, and the dispersion was increased by the duration of the acid treatment. The zeta-potential indicated the surface charge transfer and the dispersion of MWMTs. Morphological characteristics of acid-treated MWNTs were also observed using a transmission electron microscopy, X-ray diffraction, and Raman analysis, which was revealed the significantly unchanged morphologies of MWNTs by acid treatment. The hydrogen adsorption capacity of the MWNTs was evaluated by means of adsorption isotherms at 77 K/1 atm. The hydrogen storage capacity was dependent upon the acid treatment conditions and the formation of oxygen functional groups on the MWNT surfaces. The latter have an important effect on the hydrogen storage capacity.

• 생명과학회지
• /
• 제27권8호
• /
• pp.896-901
• /
• 2017

본 연구는 $CCl_4$로 간 손상이 유도된 흰 쥐에서 호박산의 간 보호 효과 정도를 알아보기 위하여 수행되었다. 실험을 하기 위해 정상군(NOR), $CCl_4$처리군(CON), 보석호박섭취군(PCON-CS)군으로 나누어 1주일 적응기간을 가진 SD계 흰 쥐에 보석호박산을 일정한 시간에 200 mg/kg으로 3주간 투여하였다. 21일째 되는 날 마지막 투여 5시간 후에 정상군을 제외한 다른 그룹의 쥐에게 $CCl_4$를 복강주사 하였다. 보석호박섭취군은 $CCl_4$처리군에 비해 AST, ALT 활성은 93.20%, 88.76% 각각 억제효과를 보였고 MDA는 $CCl_4$처리군에 비해 85.17% 억제효과를 보였다. 보석호박섭취군의 SOD와 CAT는 $CCl_4$처리군에 비해 38.65%, 47.99% 증가효과를 보였다, 결론적으로 AST, ALT 활성도와 MDA 수치는 보석호박섭취군이 $CCl_4$처리군에 비하여 유의적으로 감소하여 정상군과 비슷한 수치를 나타내었고 SOD와 CAT효소 활성은 보석호박섭취군이 $CCl_4$처리군에 비하여 증가하였다. 또한 조직학적 관찰은 사염화탄소로 유도된 간경변과 세포괴사가 호박산에 의해 예방된 것으로 나타났다. 이 데이터들로 확인해보면 $CCl_4$로 유도된 간 독성을 호박산이 간을 보호하는 결과를 나타냈으며, 이는 호박산이 간 손상에 대한 보호 효과를 가진 약물의 소재개발에 이용 될 수 있다고 본다.

• Preventive Nutrition and Food Science
• /
• 제3권2호
• /
• pp.169-174
• /
• 1998

Antimutagenic and anticarcinogenic effects of alginic acids extracted from sea mustard(SM) and sporophyII of sea mustard(SSM) were studied by Salmonella typhimurium assay system and cytotoxicity and transformation tests using C3H/10T1/2 cells, respectively. alginic acid-SM andalginic acid-SSM showed antimutagenic effects on aflatoxin B1(AFB1)and N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) in Salmonella typhimurium TA100 strain. The antimutagenic effect showed concentration dependent manner. At the 2.5mg/plate concentration , alginic acid-SSM exhibited 92% antimutagenicity against AFB1 ,while alginic acid-SM revealed 54% antimutagenictity ,s howing effectiveness of the alginic acid-SSM for the antimutagenicity. Alginic acidSSm also significantly decreased the cytotoxicity induced by 3-methylcholanthrene(MCA) and MNNG in C3H/10T1/2 cells (p<0.05). The type II and type IIItransformation foci formation by MCA and MNNG were also decreased when the alginic acid-SSM was treated, indicating that the alginic acid -SSM reduces the carcinogenesis induced by these carcinogens. The MCA-treated culture produced 10.5foci of type II +III in C3H/10T1/2 cells, however, MCA + 0.2mg/ml alginic acid-SSM treated culture formed only 1.8 foci of the types II + III in C3H/10T1/2 cells, however , MCA+0.2mg/ml alginic acid -SSM treated culture formed only 1.8 foci of the types II+ III(p<0.05). While MNNG-treated culture formed 13.0 foci, MNNG + 0.2mg/ml alginic acid -SSM treated one produced 3.0 foci of type II+III(p<0.05). These results suggest that alginic acid-SSM can effectively prevent the mutagenicities and also decrease cytotoxicity and transformation induced by some carcinogens.

• 대한치과보철학회지
• /
• 제45권5호
• /
• pp.589-600
• /
• 2007

Statement of Problem: Titanium has many advantages of high biocompatibility, physical porperties, low-weight, low price and radiolucency, but it is incompatible with conventional dental porcelain due to titanium's oxidative nature. Many previous studies have shown that they used the method of sandblast surface treatment prior to porcelain application, the researchs are processing about the method of acid etching or surface coating. Purpose: The purpose of this research is to study the effect on bond strength between titanium and porcelain when using macro-surface treatment and micro-surface treatment and macro and micro surface treatment. Material and method: In this study, we evaluated the bond strength by using 3-point bending test based on ISO 9693 after classified 7 groups-group P : polished with #1200 grit SiC paper, group SS : sandblasted with $50{\mu}m$ aluminum oxides, group LS : sandblasted with $250{\mu}m$ alumium oxides, group HC : treated with 10% hydrochloric acid, group NF : treated with 17% solution of fluoric acid and nitric acid, group SHC : treated with 10% hydrochloric aicd after sandblsting with $50{\mu}m$ alumium oxides, group SNF treated with 17% solution of fluoric acid and nitric acid. Results : Within the confines of our research, the following results can be deduced. 1. Group SS which was sandblasted with $50{\mu}m$ aluminum oxides showed the highest bond strength of 61.74 MPa and significant differences(P<0.05). The bond strengths with porcelain in groups treated acid etching after sandblasting decreased more preferable than the group treated with sandblasting only. It gives significant differences(P<0.05). 2. After surface treatments, the group treated with sandblasting showed irregular aspect formed many undercuts, in the SEM photographs. The group treated with hydrochloric acid had the sharp serrated surfaces, the group treated with the solution of fluoric acid and nitric acid had the smooth surfaces, the group with sandblasting and hydrochloric acid had irrigular and porous structure, the group with sandblasting and the solution of fluoric acid and nitric acid had crater-like surfaces. But all of the groups treated with acid etching was not found and undercut. Conclusion: In above results, average surface roughness increase, bond strength also increase, but surface topographs influences more greatly on bond strengths.