• Tuberculosis and Respiratory Diseases
• /
• v.55 no.1
• /
• pp.21-30
• /
• 2003

Background : Mucin synthesis in airways has been reported to be regulated by the epidermal growth factor receptor (EGFR) system. Epidermal growth factor receptor transactivation was identified as a critical element in G-protein-coupled receptors (GPCRs)-induced mitogenic signaling. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. This study was hypothesized that lipopolysaccharide (LPS)-induced mucin production associates with epidermal growth factor receptor transactivation, and MUC5AC production associates with epidermal growth factor receptor transactivation by G-protein-coupled receptors that regulates by metalloproteinase. Method : MUC5AC mucin production was examined in NCI-H292 cells and MUC5AC protein synthesis was assessed using ELISA. For the evaluation of mechanism of LPS-induced MUC5AC production, $TNF{\alpha}$ was measured using ELISA with or without pretreatment of heterotrimeric G-protein inhibitor, mastoparan. MUC5AC protein was measure with pretreatment of polyclonal $TNF{\alpha}$ antibody or mastoparan on LPS-induced MUC5AC production. For the evaluation of relation of G-protein and MUC5AC production, G-protein stimulant, mastopara-7, or matrix metalloproteinase, ADAM10, was added to NCI-H292 cells. MUC5AC protein was measure with pretreatment of polyclonal EGF antibody on mastoparan-7-induced MUC5AC production. Results : LPS alone did not increase significantly MUC5AC production. LPS with $TNF{\alpha}$ induced dose-dependently MUC5AC production in NCI-H292 cells. LPS increased dose-dependently $TNF{\alpha}$ secretion, which was inhibited by mastoparan. LPS with $TNF{\alpha}$-induced MUC5AC production was inhibited by neutralizing polyclonal $TNF{\alpha}$ antibody, mastoparan or AG 1472. Mastoparan-7 or ADAM10 increased dose-dependently MUC5AC production, which was inhibited by polyclonal neutralizing EGF antibody. Conclusion : In LPS-induced MUC5AC synthesis, LPS causes $TNF{\alpha}$ secretion, which induces EGFR expression. EGFR tyrosine kinase phosphorylation result in MUC5AC production. EGF-R transactivation by G-protein-coupled receptors requires matrix metalloproteinase cleavage of proHB-EGF.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.7 no.6
• /
• pp.1283-1290
• /
• 2003

Recently, PWM Buck AC-AC Converter is widely employed in various industrial applications such as voltage and power regulator, electronic transformer, phase shifter and so on. This paper presents static and dynamic modeling and complete characteristic analysis of a PWM Buck AC-AC converter. Firstly, the three phase converter system is modelled by using DQ transformation whereby we can obtain basic characteristic equations such as voltage gain and power factor as well as state equation and transfer function for control. Secondly, based on the analysis, the feedforward-feedback control technique is also proposed to obtain instantaneous duty level change whereby very fast dynamic response is achieved. Finally, the experimental results show the validity of the modeling, analysis and control.

• Korean Journal of Materials Research
• /
• v.8 no.9
• /
• pp.797-801
• /
• 1998

The cure kinetics for diglycidyl ether of bisphenol A(DGEBA)/4, 4'-methylene dianiline(MDA) system with or without lOphr of phenyl glycidyl ether(PGE)-acetamide(AcAm) was studied by autocatalytic cure expression. On the dynamic DSC curves, the exothermic peak temperature and the onset temperature of reaction decreased with the addition of PGE-AcAm. Regardless of the addition of PGE-AcAm, the shape of the conversion curve showed sigmoid, and this meant that DGEBA/MDA and DGEBA/MDA/PGE-AcAm systems followed autocatalytic cure reaction. When PGE-AcAm was added to DGEBA/MDA system, the cure rate increased about 1.2~1.4 times due to the catalytic role of hydroxyl groups in PGE-AcAm.

• 한국연소학회:학술대회논문집
• /
• 2007.05a
• /
• pp.197-201
• /
• 2007

The reattachment characteristics of propane lifted flames in laminar coflow jets influenced by AC electric fields have been investigated experimentally in low AC frequency range. The reattachment velocity and height have been measured by varying the applied AC voltage and frequency. The results showed that the reattachment of lifted flame occurred at relatively higher jet velocity with AC electric fields, comparing to that without having AC electric fields. The effect of AC electric fields became more effective at higher voltage and lower frequency in the AC frequency range larger than 30 Hz. However, in the low frequency range below 30 Hz, the reattachment velocity decreased with decreasing frequency. Consequently, there existed a transition regime, for the frequency smaller than about 30 Hz. Also, when the AC voltage was applied to the fuel nozzle at very low frequency, the reattachment process exhibited an oscillatory behavior, synchronized with the applied AC frequency.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2004.05b
• /
• pp.517-520
• /
• 2004

In this paper, a PWM Cuk AC-AC converter is modelled by using complex circuit DQ transformation whereby the equivalent model is obtained which has the complete information of the Cuk converter. Using the model, the dynamicc characteristics equations such as state equations is analytically obtained. Finally, the PSIM simulation show the validity of the modelling and analysis.

• Proceedings of the KIPE Conference
• /
• 2014.07a
• /
• pp.43-44
• /
• 2014

본 논문에서는 단상 Quasi Z-소스 AC-AC 컨버터 3대를 이용하여 3상 교류 출력전압 제어를 제안하였다. 제안된 시스템은 3대의 단상 Quasi Z-소스 AC-AC 컨버터에 종전의 간단한 듀티비 제어를 통하여 입력에 대하여 동상의 벅-부스트 출력모드와 역상의 벅-부스트 출력모드를 모두 출력하는 4상한 출력 3상 교류 전압 제어를 하였다. PSIM시뮬레이션을 통하여 종전의 듀티비 제어를 통한 동상의 부스트 모드와 역상의 벅-부스트 모드 출력 전압과 제안한 듀티비 제어에 의해 동상의 벅 모드가 출력됨으로써 단상 Quasi Z-소스 AC-AC 컨버터의 간단한 듀티비 제어만을 통하여 3상 4상한 교류 출력전압 제어가 되는 것을 확인하였다.

• Korean Journal of Materials Research
• /
• v.7 no.6
• /
• pp.460-463
• /
• 1997

에폭시 수지 계의 경화반응 속도를 증가시키고 기계적 물성을 향상시키기 위해 합성 pheny1 glycidy1 ether(PGE)-acetamide(AcAm)를 diglycidy1 ether of bispenol A(DGEBA)/4,4'-methylene dianiline(MDA)계에 도입하였다. PGE와 AcAm을 2:1의 몰비로 혼합한 후 18$0^{\circ}C$에서 1시간 반응시켜서 PGE-AcAm을 합성하였다. 5phr의 PGE-AcAm이 첨가되었을 때 인장강도가 15% 개선되었으며, 그 이후로는 PGE-AcAm을 합성하였다. 5phr의 PGE-AcAm이 첨가되었을 때 인장강도가 15% 개선되었으며, 그 이후로는 PGE-AcAm의 함량에 관계없이 거의 비슷한 값을 나타내었다. 반면에유리전이 온도(Tg)와 충격강도는 PGE-AcAm의 함량이 증가함에 따라 감소하였다. 파단면은 PGE-AcAm이 첨가됨으로써 더 복잡한 형상을 나타내었다.

• Proceedings of the KIPE Conference
• /
• 2016.07a
• /
• pp.435-436
• /
• 2016

본 논문에서는 3상 Quasi Z-소스 AC/AC 전력변환기를 제안한다. 제안된 전력변환기는 3대의 단상 Quasi Z-소스 AC/AC 컨버터로 구성되어 있으며, 간단한 듀티 비 제어만으로도 동상 및 역상의 벅-부스트 출력 전압의 발생이 가능하다. 제안된 방식은 PSIM 시뮬레이션을 통하여 타당성을 확인하였다.

• Proceedings of the KIEE Conference
• /
• 2003.04a
• /
• pp.166-169
• /
• 2003

In this paper, a PWM Buck-Boost AC-AC converter for improvement of power quality of custom power is presented. The PWM Buck-Boost AC-AC converter is modelled by using circuit DQ transformation whereby the design guideline is obtained. Based on the analysis, the converter system is implemented with the design criteria and the experimental results show the validity of modelling and analysis.

• Proceedings of the KIPE Conference
• /
• 2004.07b
• /
• pp.579-582
• /
• 2004

This paper presents controller design of a static var compensator using PWM Cuk AC-AC converter. The PWM Cuk AC-AC converter is modelled by using complex circuit DQ transformation and perturbed around the operating point whereby the small signal system characteristics is analytically obtained. Finally, the PSIM simulations show the validity of the modelling and analysis.