• Title/Summary/Keyword: Abnormal gait

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Transient asymptomatic white matter lesions following Epstein-Barr virus encephalitis

  • Jang, Yoon-Young;Lee, Kye-Hyang
    • Clinical and Experimental Pediatrics
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    • v.54 no.9
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    • pp.389-393
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    • 2011
  • We present the case of a patient with Epstein-Barr virus (EBV) encephalitis who developed abnormal white matter lesions during the chronic phases of the infection. A 2-year-old-boy was admitted for a 2 day history of decreased activity with ataxic gait. The results of the physical examination were unremarkable except for generalized lethargy and enlarged tonsils with exudates. Brain magnetic resonance imaging (MRI) at admission showed multiple high signal intensities in both basal ganglia and thalami. The result of EBV polymerase chain reaction (PCR) of the cerebral spinal fluid was positive, and a serological test showed acute EBV infection. The patient was diagnosed with EBV encephalitis and recovered fully without any residual neurologic complications. Subsequently, follow-up MRI at 5 weeks revealed extensive periventricular white matter lesions. Since the patient remained clinically stable and asymptomatic during the follow-up period, no additional studies were performed and no additional treatments were provided. At the 1-year follow-up, cranial MRI showed complete disappearance of the abnormal high signal intensities previously seen in the white matter. The patient continued to remain healthy with no focal neurologic deficits on examination. This is the first case of asymptomatic self-limited white matter lesions seen in serial MRI studies in a Korean boy with EBV encephalitis.

Biomechanical Analysis of Lower Limbs on Speed of Nordic Walking (노르딕워킹의 속도에 따른 하지 관절의 운동역학적인 분석)

  • Yang, Dae-Jung;Lee, Yong-Seon;Park, Seung-Kyu;Kang, Jeong-Il;Lee, Joon-Hee;Kang, Yang-Hoon
    • Korean Journal of Applied Biomechanics
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    • v.21 no.3
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    • pp.383-390
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    • 2011
  • In this study, 26 normal subjects were studied to compare the biomechanical Analysis of Lower Limbs on Speed of Nordic Walking. The biomechanical variables were determined by performing three-dimensional gait analysis, and the measurements items were spatial and temporal parameters; vertical ground reaction force; and moments of the hip, knee, and ankle joints. The purpose of this study based on the speed of Nordic Walking to the vertical ground reaction force and joint moments of each were analyzed. Nordic Walking with poles while being whether this weight is reduced to load, not the improvement of muscle activity by identify Nordic walking is to allow efficient. The results of the analysis were follows. The spatial parameters of step length, stride length significantly increased with increase in velocity(p<0.001). The temporal parameters of step time, stride time, the duration of double support use, and the duration of single support use also significantly decreased with increase in velocity(p<0.001), but cadence significantly increased(p<0.01). Analysis of the changes in ground reaction force revealed that vertical ground reaction force significantly increased at the initial contact and the terminal stance and decreased at the mid stance with increase in velocity(p<0.001). Moments of the hip and knee joints significantly in creased with increase in velocity whereas that of the ankle joint did not. Gait analysis revealed that weight-bearing decreased and moments of the hip and knee joints increased with increase in velocity(p<0.01). The results of this study may help people perform Nordic walking efficiently and Nordic walking can be used in the gait training of people with an abnormal gait.

Acute Toxicity Test of KH-502 (Flupyrazofos) in Rats and Mice (KH-502의 랫트 및 마우스를 이용한 급성독성시험)

  • 송시환;김형진;신천철;임광현;하창수;한상섭
    • Toxicological Research
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    • v.14 no.2
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    • pp.227-235
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    • 1998
  • KH-502 (Flupyrazofos), a new organophosphorus insecticide synthesized by Korea Re-search Institute of Chemical Technology, was found to be effective against diamond-back moth(Plutella xylostella). This study was carried out to determine the acute toxicity of KH-502 in Sprague-Dawley rats and ICR mice. The test article was orally or dermally administered to the animals. Death, tremors, salivation, lacrimation, abnormal gait and corneal opacity were observed. Decrease in body weight gain was observed in all treatment groups. At necropsy, dark red coloration of lung, enlargement of adrenal glands and atrophy of spleen were observed. The oral $LD_{50}$ value was 372 mg/kg in male rats, 605 mg/kg in female rats, 186 mg/kg in male mice, and 115 mg/kg in female mice. And the dermal $LD_{50}$ was 4086 mg/kg in male and 3881 mg/kg in female rats.

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Walking Pattern Analysis Using an Acceleration Sensor Device

  • Hong, Ju-Hee;Han, Kap-Soo;Kim, Kyungho
    • Journal of Electrical Engineering and Technology
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    • v.12 no.1
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    • pp.396-401
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    • 2017
  • In this paper, a device to analyze gait pattern was developed by using a 2-axis acceleration sensor attached to the foot. The 1st low-pass filter was adapted to limit the frequency band up to 5 Hz. An algorithm to detect the peak value exceeding the threshold voltage of an X-axis acceleration sensor and a Z-axis acceleration sensor was developed and normal and abnormal walking patterns were thus differentiated. Also, MCU and Bluetooth were combined to transfer the data to other MCUs to display on an LCD; the size of the device could then be reduced. The new algorithm and the device allowed the individual walking patterns to be easily measured at a low cost and with less restriction on activities compared to conventional multiple pressure sensors or motion camera system.

Evaluation of Clinical Signs on Equine Coital Exanthema in Thoroughbred Horses (Thoroughbred 말에 발생한 구진의 임상증상 평가)

  • Yang, Jae-Hyuk;Lee, Kyoung-Kap;Lim, Yoon-Kyu
    • Journal of Veterinary Clinics
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    • v.28 no.4
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    • pp.369-374
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    • 2011
  • Coital exanthema of Thoroughbred horses had occurred firstly in Republic of Korea. This study was performed to evaluate clinical features of coital exanthema, and provide veterinary knowledge to equine practitioner as well as horse farms. The method was clinical, clinical pathology and sexual hormone, electron microscope and libido examination. Five stallions of 27, 45 broodmares of 416 showed clinical symptoms but 124 foals and a teaser did not show any abnormal appearance. Five stallion had papule, pustule, crust around a glans, body of penis, prepuce and remain decolorized spot after treatment. One laceration of glans and 3 gait disorder had been observed but it did not affect libido. Forty-five broodmares localized had papule, pustule, crust, and ulceration around perineal region, vulva, mucocutaneous junction remain decolorized spot after treatment.

Analysis of Clinical Measurement Methods of Lower Extremity Alignment (하지정렬의 임상적 측정방법에 대한 분석)

  • Kong Hee-Kyung;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.16 no.2
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    • pp.17-21
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    • 2004
  • We need to study about lower extremity alignment because the structure dictates the function of lower extremity. Through lower extremity alignment assessment in static posture, we recognize abnormal structural conditions which could affect dynamic motion such as gait. To evaluate of lower extremity alignment provide so many useful information, but method of measurement is so limited. Therefore, this review will assist understanding for measurement of lower extremity alignment in static posture. From now on study about the objective measurement method must be achieved much more in physical therapy.

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Measurement Methods of Lower Extremity Alignment in Static Posture (정적 자세에서 하지정렬 측정방법에 관한 고찰)

  • Kong Hee-Kyung;Cho Hyun-Rae;Bae Sung-Soo
    • The Journal of Korean Physical Therapy
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    • v.15 no.1
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    • pp.1-8
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    • 2003
  • We need to study about lower extremity alignment because the structure dictates the function of lower extremity. Through lower extremity alignment assessment in static posture, we recognize abnormal structural conditions which could affect dynamic motion such as gait. To evaluate of lower extremity alignment provide so many useful information, but method of measurement is so limited. Therefore, this review will assist understanding for measurement of lower extremity alignment in static posture. From now on study about the objective measurement method must be achieved much more in physical therapy.

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A Case of Deep Vein Thrombosis Associated with Myositis due to Streptococcus pyogenes (Streptococcus pyogenes 근염에 심부 정맥 혈전증이 동반한 1례)

  • Lee, Jae Sook;Jang, Tae Young;Ahn, Young Min
    • Pediatric Infection and Vaccine
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    • v.16 no.1
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    • pp.87-91
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    • 2009
  • A 5-year-old boy was admitted to the hospital with a high fever and abnormal gait. Magnetic resonance imaging showed extensive swelling of the quadriceps and adductor muscles around the right hip and anterior thigh. A duplex scan demonstrated a thrombus from the external iliac vein to below the popliteal vein. The blood culture revealed Streptococcus pyogenes. The patient was immediately treated with antibiotics and anticoagulants. Follow-up sonography demonstrated complete disappearance of the venous thrombosis. We report a case of streptococcal myositis complicated by deep vein thrombosis.

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Adrenomyeloneuropathy with cerebral involvement due to a novel frameshift variant in ABCD1 gene

  • Kim, Hye Weon;Kim, Hyunjin;Jeong, Dongyoung;Chung, Kyuyoon;Lee, Eun-Jae;Lim, Young-Min;Kim, Kwang-Kuk
    • Annals of Clinical Neurophysiology
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    • v.23 no.1
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    • pp.61-64
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    • 2021
  • Adrenoleukodystrophy (ALD) is the most common peroxisomal disorder caused by mutations in the gene, ABCD1, causing abnormal accumulation of very-long-chain fatty acids in the nervous system and adrenal glands. There are various clinical manifestations of ALD. Here we report a 47-year-old male with adrenomyeloneuropathy with cerebral involvement who exhibited progressive gait disturbance and cognitive impairment. A novel frameshift variant (c.95del [p.Val32Alafs*36]) in exon 1 of ABCD1 was identified. This report provides additional information regarding the various clinical characteristics of ALD.