• 공업화학
• /
• 제19권6호
• /
• pp.661-667
• /
• 2008

본 연구에서는 LCD 백라이트용 휘도향상 편광필름으로 사용하기 위해, 콜레스테릭 액정(CLC)을 합성하여 네미틱 액정과 혼합한 다음 이들이 충진된 모듈을 제작하였다. 광확산필름에 의해 면광원화된 빛을 통과시킬 때, LCD 백라이트상에서 이들의 투과광 증폭 및 편광능력에 대한 특성을 연구하였다. 합성된 콜레스테릭 액정의 특성은 UV/Visible 스펙트럼과 편광현미경(POM) 등으로 평가하였다. 여러 종류의 선형 카르복실산을 콜레스테롤 분자에 도입하여 콜레스테릭 메소젠 사이의 유연격자를 이루도록 유도하여 각 층에서 일정한 방향성을 유지하도록 하였다. 또한 CLC필름을 적층하여 가시광선대에서 편광능력, 휘도향상 및 투과파장영역을 넓히고 백라이트 유니트의 밝기를 향상시키는 모듈로 적용할 수 있었다.

• Journal of Microbiology and Biotechnology
• /
• 제31권8호
• /
• pp.1163-1174
• /
• 2021

Casein-derived antioxidant peptides by using microbial proteases have gained increasing attention. Combination of two microbial proteases, Protin SD-NY10 and Protease A "Amano" 2SD, was employed to hydrolyze casein to obtain potential antioxidant peptides that were identified by LC-MS/MS, chemically synthesized and characterized in a oxidatively damaged HepG2 cell model. Four peptides, YQLD, FSDIPNPIGSEN, FSDIPNPIGSE, YFYP were found to possess high 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging ability. Evaluation with HepG2 cells showed that the 4 peptides at low concentrations (< 1.0 mg/ml) protected the cells against oxidative damage. The 4 peptides exhibited different levels of antioxidant activity by stimulating mRNA and protein expression of the antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px), as well as nuclear factor erythroid-2-related factor 2 (Nrf2), but decreasing the mRNA expression of Kelch-like ECH-associated protein 1 (Keap1). Furthermore, these peptides decreased production of reactive oxygen species (ROS) and malondialdehyde (MDA), but increased glutathione (GSH) production in HepG2 cells. Therefore, the 4 casein-derived peptides obtained by using microbial proteases exhibited different antioxidant activity by activating the Keap1-Nrf2 signaling pathway, and they could serve as potential antioxidant agents in functional foods or pharmaceutic preparation.

• 기술혁신연구
• /
• 제11권1호
• /
• pp.195-214
• /
• 2003

Sweden's regional innovation system is built mainly on innovative clusters, several of them - in automobile, steel, new materials, information and telecommunication, and bioscience - world-class. Most successful clusters were developed at local bases imbued with local history. In fact, a cluster's competitiveness is intimately related to its closeness of fit with its local environment. Geographically dispersed clusters in Sweden - some national, others local, and some local but deemed members of a national cluster as well - have already created many new competitive products and services. In 2001, Sweden has eight national and nine regional clusters, and envisioned eleven national and five regional clusters more. The experience of Swedish clusters indicate several elements that determine the ability of cluster policies to promote and strengthen regional economic growth. Cluster policies require strong public sector support, particularly in the form of providing basic national conditions. Regional cluster policies place new demands on national and regional industrial policies. All policies must be closely interwoven without compromising their primary allegiance to their respective areas.

• Carbon letters
• /
• 제22권
• /
• pp.42-47
• /
• 2017

In this paper, the in vitro biocompatibility of graphene film (GF) with osteoblasts was evaluated through cell adhesion, viability, alkaline phosphatase activity, F-actin and vinculin expressions, versus graphite paper as a reference material. The results showed that MG-63 cells exhibited stronger cell adhesion, better proliferation and viability on GF, and osteoblasts cultured on GF exhibited vinculin expression throughout the cell body. The rougher and wrinkled surface morphology, higher elastic modulus and easy out-of-plane deformation associated with GF were considered to promote cell adhesion. Also, the biomineralization of GF was assessed by soaking in simulated body fluid, and the GF exhibited enhanced mineralization ability in terms of mineral deposition, which almost pervaded the entire GF surface. Our results suggest that graphene promotes cell adhesion, activity and the formation of bone-like apatite. This research is expected to facilitate a better understanding of graphene-cell interactions and potential applications of graphene as a promising toughening nanofiller in bioceramics used in load-bearing implants.

• 유통과학연구
• /
• 제10권4호
• /
• pp.7-11
• /
• 2012

"Great things in business are never done by one person; they're done by a team of people." By Steve Jobs, 2003. As define by Linda Naiam - Creativity is the act of turning new and imaginative ideas into reality. Creativity involves two processes: thinking, then producing. Innovation is the production or implementation of an idea. If you have ideas, but don't act on them, you are imaginative but not creative. So in order to maintain the pace with the changing business scenario and coping with the competition Innovation and Creativity is considered a mandatory tool for a business to exist and grow in market. Whether a company is Employee centric or Business centric Innovation and creativity has to have its space in order to keep a business ahead of others in the Market. Also it's not just the competition which has led to the Innovation and Creativity in Business practices it's also the demanding chunk of consumers and customers who are aware and prefer maximum choices before making a final deal. Another reason as to why there is a change in business practices is the globalization of businesses where you need to rope in the Innovative ideas to launch and sustain in new market. There had been tremendous shift in business practices but to give a room to innovative ideas and implement that creativity need ample to space and vision along with an attitude where in you can resist for getting an immediate results from innovative business practices. Corporate Creativity is characterized by the ability to perceive the world in new ways, to find hidden patterns, to make connections between seemingly unrelated phenomena, and to generate solutions. Generating fresh solutions to problems, and the ability to create new products, processes or services for a changing market, are part of the intellectual capital that give a company its competitive edge. Creativity is a crucial part of the innovation equation. The innovation and creativity is not limited to any area of business, it can start from your waiting lounge to your board room meeting depending upon how the things are perceived and implemented for the betterment of people and business. The purpose of this research is to understand the latest creative business approaches and practices that organizations are following to be different from their competitors. Also this shift from generic business practices to the Innovative and Creative approach seems to take the business into new world. This approaches means starting from the bottom of the Pyramid and finally touching the pinnacles in Innovation and creativity. The paper will discuss on the various areas of business where in innovative approaches can be roped in and sets new bench mark altogether in the business arena.

• 산경연구논집
• /
• 제5권1호
• /
• pp.17-25
• /
• 2014

Purpose - Nowadays, the innovative design concept is being implemented in product design. In order to satisfy market trends and the demand for quality, designers should employ customer satisfaction questionnaires and analyze them with various experimental processes. Research design, data, and methodology - These methodologies would help designers have a better understanding of their customers and judge the market size and clustering validity, by diverse product strategies, for dealing with the rapid change prevailing in the market today. Results - By considering the innovative design with regard to telephones as an experimental case, the study investigates and demonstrates how the product can benefit from market-oriented and customized management concepts, when creative design ability is utilized for developing the product. Conclusions - Along with the benefit of having an innovative product value, the product can stimulate progress inthe development of the enterprise management, which has emerged as the main issue in the area of social and economic development in every developed country.

• Asian Journal of Innovation and Policy
• /
• 제7권3호
• /
• pp.581-605
• /
• 2018

In the soft drink industry, especially small and medium enterprises in Japan, there is a possibility of conversion from a labor-intensive industry to a capital-intensive. The demand for soft drinks may not be satisfied in the summer because the supply is too low to meet the demand. To address this situation, this paper proposes optimal investment that integrates demand uncertainty, based on real options approach (ROA) and seasonal autoregressive integrated moving average. Two alternative options are compared and evaluated. One is the Bermudan option: to employ additional workers to elevate efficiency in summer and laying off in winter, this attitude is repeated each year. The other is the American option: to replace equipment to increase machine ability throughout the year. Results in ROA show that the highest improvement is gained if the two options are in a symbiotic relationship. Soft drink producers should search for replacing equipment, using the employees repeatedly. A temporary decision is not equal to an infinite decision.

• 기술혁신연구
• /
• 제31권3호
• /
• pp.201-230
• /
• 2023

혁신조달 제도는 전략적 공공조달 정책의 일환으로 혁신제품 지정 및 우선구매제도를 활용해 기업의 혁신역량 향상과 공공부문의 사회문제 해결능력 향상을 동시에 추구하는 정책으로 도입됐다. 혁신제품에 대한 시범구매 사업은 2019년에 처음 도입됐으며 2020년부터 정부 부처의 혁신제품 지정·발굴 체계가 확립된 후 혁신제품 우선구매제도가 본격적으로 실시됐다. 이에 본 연구는 혁신조달 제도가 본격적으로 시행된 이후 해당 제도의 기업지원 효과에 초점을 맞춰 정량적 분석을 진행했다. 이를 위해 2017년에서 2021년까지의 기업 재무제표 및 고용 자료를 이용했으며, 분석방법으로 성향점수매칭(PSM) 및 이중차분(DID) 방법을 활용했다. 본 연구를 통해 혁신조달 제도가 기업성장과 고용증대에 기여했으며 추가적인 공공 및 민간판로 개척 효과를 창출했음을 확인할 수 있었다. 한편 혁신조달 참여기업이 제품지정 종료 이후에도 자생성을 갖추기 위해서는 혁신제품 지정기업과 기존의 중소기업 지원정책을 적극 매칭하는 등 혁신조달 제도를 고도화할 필요가 있다.

• Asian-Australasian Journal of Animal Sciences
• /
• 제33권5호
• /
• pp.812-824
• /
• 2020

Objective: The aim of this work was to assess the effect of fermented blueberry (FB; 2%, 4%, and 6%) on the oxidative stability and volatile molecule profiles of emulsion-type sausage stored at 4℃ for 28 days. Methods: The antioxidant activity of FB was determined through radical-scavenging activity against 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and hydroxyl radicals. Four formulations of sausage treatments with different FB levels (0%, 2%, 4%, 6%) were prepared, then peroxide value (POVs), thiobarbituric acid-reactive substances (TBARS) values, protein carbonyls and thiol groups were measured. The aroma profiles of sausages for each treatment was also determined. Results: The half maximal inhibitory concentration indicated that FB had greater scavenging ability than ascorbic acid against DPPH and hydroxyl radicals. Sausages with FB significantly retarded increases in POVs and TBARS, as well as in the content of protein carbonyls during all storage days (p<0.05). Particularly, 4% and 6% FB-treated sausages had better oxidation inhibition effects. However, FB accelerated the reduction in thiol groups (p<0.05). Additionally, FB inhibits the excessive formation of aldehyde compounds; for example, hexanal, which may cause rancid flavors, decreased from 58.25% to 19.41%. FB also created 6 alcohols (i.e., 2-methyl-1-propanol, 3-methyl-1-butanol, and phenylethyl alcohol), 5 ester compounds (i.e., ethyl acetate, ethyl lactate, and ethyl hexanoate) and 3-hydroxy-2-butanone in the sausages that contribute to sausage flavors. The principal component analysis showed that the aroma profiles of sausages with and without FB are easily identified. Conclusion: The addition of FB could significantly reduce the lipid and protein oxidation and improve oxidative stability for storage. Also, adding FB could inhibit rancid flavors and contribute to sausage flavors.

• 한국산학기술학회논문지
• /
• 제10권11호
• /
• pp.3340-3353
• /
• 2009

본 논문은 산학협력 네트워크 활동이 중소 벤처기업의 기술혁신 성과에 어떻게 미치는지를 연구한 것으로 산학협력을 통한 공동장비 활용협력, 기술인력 지원 및 교류협력, 공동 기술개발 및 기술지도 협력의 세 가지 요인이 기업가 역량과 흡수 능력에 어떤 영향을 미치는지와 최종적으로 이러한 기업가 역량과 흡수 능력이 중소벤처기업의 기술혁신성과에 미치는 영향을 파악하기 위하여 시화반월지구에 위치한 1100여개의 중소벤처기업을 대상으로 설문 조사를 실시하였으며, 설문 결과를 구조방정식 모형에 적용하여 개별 요소간의 상관관계를 파악하여 이를 검정하였다. 또한 산학협력 체결 기업과 미체결기업 간의 기술 혁신성과를 비교함으로써 중소벤처기업의 산학협력 활용능력을 제고하기 위한 방안을 수립하였다. 구조방정식을 통한 개별 항목의 상관관계를 분석한 결과 공동장비 활용협력, 기술인력 지원 및 교류협력, 공동 기술개발 및 기술지도 협력 모두 기업가 역량에 큰 영향력을 미쳤으나, 지식흡수능력에는 부분적으로 영향을 미쳤으며, 최종적으로 기업가 역량과 지식흡수 능력 중 기업가 역량만 기술혁신 성과에 영향력을 미치는 것으로 조사되었다. 또한 위의 요소들이 업종별, 제품성장 단계별로 미치는 영향은 기업가 역량에는 동일하게 나타나고 다른 요소들은 차이가 있는 것으로 나타나 산학협력에 대한 다른 전략이 마련되어야 함을 알 수 있다. 또한 산학협력 체결 기업은 미체결 기업에 비해 기술개선, 신제품 개발 건수, 공정개선 건수의 항목이 산학협력 미체결 기업보다 높은 것으로 나타났다.