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Physiologically Active Fatty Acids their Metabolism and Function (생리활성지방산;그 대사와 기능)

  • Mitsu, Kayama
    • Journal of the Korean Applied Science and Technology
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    • v.13 no.3
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    • pp.15-24
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    • 1996
  • Essentiality was proposed in the field of lipid by Burr and Burr in 1929. When rats were raised on the fat-free diet, their growth retarded and their skin and tails showed the characteristic deficient symptoms, which were relieved by the addition of ${\omega}6(n-6)$ polyunsaturated fatty acids as linoleic(LA) and arachidonic(AA) acids to the basal diet. LA is dehydrogenated to ${\gamma}-linolenic$ acid(GLNA) by ${\Delta}6$ desaturase, then GLNA is 2 carbon chain elongated by elongase to $dihomo-{\gamma}-linolenic$ acid(DGLNA), which is desaturated by ${\Delta}5$ desaturase to AA. These acids are called LA family or ${\omega}6(n-6)$ polyunsaturated fatty acids(PUFA). ${\alpha}-Linolenic$ acid(ALNA) is converted through the series of desaturation and elongation steps to docosahexaenic acid(DHA) via eicosapentaenoic acid(EPA). These acids belong to ALNA family or ${\omega}3(n-3)$PUFA. Human who consume large amounts of EPA and DHA, which are present in fatty fish and fish oils, have increased levels of these two fatty acids in their plasma and tissue lipids at the expense of LA and AA. Alternately, vegetarians, whose intake of LA in high, have more elevated levels of LA and AA and lower levels of EPA and DHA in plasma lipids and in cell membranes than omnivores. AA and EPA are metabolized to substances called eicosanoids. Those derived form AA are known as prostanocids(prostaglandins and prostacyclins) of the 2-types and leukotrienes of the 4-series, whereas those derived from EPA are known as prostanoids of the 3-types and leukotrienes of the 5-series. DGLNA is a precursor of the 1-types of prostaglandins. The metabolites of AA and EPA have competitive functions. Ingestion of EPA from fish or fish oil replaces AA from membrane phospholipids in practically all cells. So this leads to a more physiological state characterized by the production of proatanoids and leukotrienes that have antithrombic, antichemotactic, antivasoconstrictive and antiinflammatory properties. It is evident that ${\omega}3$ fatty acids can affect a number of chronic diseases through eicosanoids alone.

Implementation of fast stream cipher AA128 suitable for real time processing applications (실시간 처리 응용에 적합한 고속 스트림 암호 AA128 구현)

  • Kim, Gil-Ho;Cho, Gyeong-Yeon;Rhee, Kyung Hyune;Shin, Sang Uk
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.10
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    • pp.2207-2216
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    • 2012
  • Recently, wireless Internet environment with mobile phones and wireless sensor networks with severe resource restrictions have been actively studied. Moreover, an overall security issues are essential to build a reliable and secure sensor network. One of secure solution is to develop a fast cryptographic algorithm for data encryption. Therefore, we propose a 128-bit stream cipher, AA128 which has efficient implementation of software and hardware and is suitable for real-time applications such as wireless Internet environment with mobile phones, wireless sensor networks and Digital Right Management (DRM). AA128 is stream cipher which consists of 278-bit ASR and non-linear transformation. Non-linear transformation consists of Confusion Function, Nonlinear transformation(SF0 ~ SF3) and Whitening. We show that the proposed stream cipher AA128 is faster than AES and Salsa20, and it satisfies the appropriate security requirements. Our hardware simulation result indicates that the proposed cipher algorithm can satisfy the speed requirements of real-time processing applications.

Effects of Intra-particle Composition on the Adhesive Properties and Water Dispersity of Water Dispersible Acrylic Emulsion Pressure Sensitive Adhesive (입자 내 조성 변화가 수분산성 아크릴 에멀젼 점착제의 점착 물성과 수분산성에 미치는 영향)

  • Seo, In Seon;Lee, Myung Cheon
    • Applied Chemistry for Engineering
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    • v.18 no.5
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    • pp.444-448
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    • 2007
  • The effects of intra-particle composition on the adhesive properties and water dispersity of acrylic emulsion type pressure sensitive adhesives (PSAs) were investigated. In the case of PSA having uniform intra-particle composition, the higher holding strength made the water dispersity lower. By changing the intra-particle composition in hard core/soft shell type, however, it was possible to get PSAs showing both high holding strength and water dispersity. When the weight ratio of MAA/AA is 4/1, high holding strength, but low initial tack and very low water dispersity were observed in both cases of higher contents of (AA+MAA) in core and shell area. When the weight ratio of MAA/AA is 1/4, however, higher water dispersity and lower holding strength were indicated in the case of higher contents of (AA+MAA) in shell area.

Effects of Ultrasound and Ascorbic acid Cotreatment on Browning of Fresh-cut 'Tsugaru' Apples (초음파 및 Ascorbic acid 병용처리가 신선절단 '쓰가루' 사과의 갈변에 미치는 영향)

  • Cho, Jeong-Seok;Jeong, Moon-Cheol;Moon, Kwang-Deog
    • Food Science and Preservation
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    • v.19 no.3
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    • pp.323-327
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    • 2012
  • The effects of ultrasound and ascorbic acid cotreatment on the browning inhibition and microbial growth of fresh-cut Tsugaru apples were investigated. The prepared samples were dipped in distilled water (Cont) or 1% (w/v) ascorbic acid solution (AA) and were then ultrasonicated in distilled water (US) or 1% (w/v) ascorbic acid solution (AA+US). The samples were then packed in a 0.04mm polypropylene bag ($20{\times}15$ cm) and were stored at $10^{\circ}C$ for eight days. The AA+US treated samples showed high $L^*$ and low $a^*$, $b^*$ values as well as inactivated PPO activity. The growth of the total aerobic bacteria also inhibited the AA+US treated samples more. The physicochemical properties were not different among all the samples. It was demonstrated in this paper that the ultrasonication treatment with ascorbic acid prevented the enzymatic browning of and microbial growth in fresh-cut Tsugaru apples.

Effects of meal processing of black soldier fly on standardized amino acids digestibility in pigs

  • Abdolreza Hosseindoust;SangHun Ha;JunYoung Mun;JinSoo Kim
    • Journal of Animal Science and Technology
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    • v.65 no.5
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    • pp.1014-1023
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    • 2023
  • The aim of this study was to investigate the effect of incorporating black soldier fly (BSF) larvae and its processed form as an alternative source of protein to fish meal (FM) on the digestibility of amino acids (AA) in weaned pigs. Four cannulated pigs with an initial bodyweight of 13.25 ± 0.25 kg and aged 30 days were subjected to a 4 × 4 Latin square design with three treatments, as well as a nitrogen-free treatment. The diets used for each treatment consisted of a FM diet, a diet containing BSF larvae meal (BSFM), and a diet containing extruded BSF (BSFE). The study was conducted over four stages, with a total duration of 28 days. The apparent ileal digestibility (AID) of protein was higher in the FM treatment compared with the BSFM. Among essential AA, the AID of Arg, His, Leu, and Thr were higher in the FM compared with the BSFM and BSFE. A greater AID of Ile and Phe was observed in pigs in the FM treatment compared with the BSFM. The average AA digestibility did not show any difference between treatments. Among non-essential AA, the AID of Ala (p = 0.054) and Glu (p = 0.064) tended to be increased in the FM compared with the BSFM. Among essential AA, the standardized ileal digestibility (SID) of Arg, His, Ile, and Leu were higher in the FM compared with the BSFM. Among non-essential AA, the SID of Cys (p = 0.074) tended to be increased in the FM compared with the BSFM. In conclusion, the processing and thermal conditioning techniques utilized for BSF larvae meal showed a tendency for increased AA digestibility. Therefore, when formulating a diet, it is important to take into account the difference in AA digestibility between FM and BSFM.

Giant Magnetoresistance of Antiferromagnetic Cr-Al based Multilayer Spin-Valve with Anti-Corrosion and Thermal Stability (내열 내식용 Cr-Al반강자성계 스핀밸브막의 거대자기저항 효과)

  • 김병수;이성훈;이찬규
    • Journal of the Korean Magnetics Society
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    • v.8 no.6
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    • pp.362-368
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    • 1998
  • The magnetic properties, thermal stability and anti-corrosion properties of $Cr_86Al_14$ spin valves multilayers were studied. It was found that the magnetic properties of $Cr_86Al_14$ spin valves depend on the thickness of antiferromagnetic, ferromagnetic and non-ferromagnetic layers. Exchange coupled field ($H_{ex}$) and magnetoresistance ratio (%) showed the largest value of 20 Oe, 2 % in $glass/Cr_{86}Al_{14}(600 $\AA$)/Ni_{81}Fe_{19}(50$\AA$)/Cu(40 $\AA$)/Ni_{81}Fe_{19}(40 $\AA$)$ spin valves. The $H_{ex}$ MR ratios (%) of CrAl and FeMn spin valves were decreased with increasing annealing temperatures and were lost at 150 $^{\circ}C$, 250 $^{\circ}C$ respectively. Based on these result, it was elucidated that CrAl is more thermally stable than FeMn. It was also shown that there was no change of $H_{ex}$ MR ratios in CrAl, while FeMn was changed and lost 15 days later in corrosion resistance test under 35 $^{\circ}C$, 90 % humidity condition. FeMn was found to be pitted and peeled off 15 days later by SEM micrographic analysis.

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THE STUDY ON EFFECTS OF THE PLATELET-DERIVED GROWTH FACTOR-AA, BB ON THE CELLULAR ACTIVITY OF THE HUMAN PERIODONTAL LIGAMENT CELLS (Platelet-derived growth factor-AA, BB가 치주인대세포의 세포활성에 미치는 영향에 대한 연구)

  • Oh, Sang-Deok;Lee, Jae-Mok;Suh, Jo-Young
    • Journal of Periodontal and Implant Science
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    • v.24 no.2
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    • pp.303-320
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    • 1994
  • Current acceptable methods For promotin gperiodontal regeneration are base on removal of diseased soft tissue, root treatment, guided tissue regeneration, inteoduction of new graft materials and biological mediators. Platelet-derived growth factor(PDGF) is one of polypeptide growth factor. PDGF has been reported as a biological mediator which regulates activities of wound healing process including the cell proliferation, migration and metabolism. The purposes of this study is to evaluate the effects of PDGF-AA, BB on the periodontal ligament cells to use as a regeneration promoting agent of periodontal tissue. Human periodontal ligament cells were prepared from the first premolar tooth extracted for the orthodontic treatment and were cultured in DMEM/10% FBS at the $37^{\circ}C$, 5% $CO_2$ incubator. Author measured the DNA synthesis, total protein, collagen and noncollagenous protein synthesis and alkaline phosphatase activity according to the concentration of PDGF-AA and BB(0, 0.1, 1, 10, 100ng/ml). The results were as follows : The DNA synthetic activity was increased dose dependently by PDGF-AA and BB. The maximum mitogenic effect was at the 100ng/ml of PDGF-AA and 10ng/ml of PDGF-BB. The total protein, collagen and noncollagen systhesis was increased dose dependently by PDGF-AA and BB. The % of collagen was slightly decresed according to the concentration of PDGF-AA and BB. The effect of PDGF-AA and BB were not specific for collagen synthesis since it also increased noncollagenous protein synthesis. The effect of PDGF-AA and BB on alkaline phosphatase activity did not show any significant, meanwhile the alkaline phosphatase activity of 14 days group showed significnat increase. In conclusion, PDGF-AA and BB may have important roles in stimulation of DNA synthesis in human periodontal ligament cells, which means an increase in collagen-synthesizing cells, and may be useful for clinical application in periodontal regenerative procedures.

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Determination of Seed Purity in Radish (Raphanus sativus L.) Using Allozyme (알로자임에 의한 무 씨의 순수성 검증)

  • Huh, Man-Kyu
    • Journal of Life Science
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    • v.18 no.7
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    • pp.907-911
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    • 2008
  • Radish (Raphanus sativus L.) is one of very important crop plants in the world. It is very important to determine hybrid seed quality in the production of hybrid Brassica vegetable seeds to avoid unacceptable contamination with self-inbred (sib) seeds. The allozyme for evaluating seed purity in a commercial $F_1-hybrid$ radish cultivar is demonstrated. Three hundred sixty seeds from the male and female harvest were subsequently screened for seed purity using 27 isozyme loci. Especially, F1 hybrids of radish, Per-1 ($aa{\times}bb$), Lap-1 ($aa{\times}bb$), Est-1 ($aa{\times}bb$) were presented clear hybrid bands. Est-1 locus revealed that 15 (8.3%) seeds from the female harvest and 26 (14.4%) seeds from the male harvest were sibs. It maintains higher than average level of genetic diversity compared with their correspondent parents. Shannon's index of phenotypic diversity (I) of hybrids was the highest of all accessions (R. sativus L. cv. Daepeng, R. sativus L. cv. Backza, and their hybrids). The allozyme may lead to a better insight into the hybrid seed purity.

RAMAN SPECTROSCOPY IN SYMBIOTIC STARS (공생별에서 라만 산란선의 형성)

  • LEE HEE-WON
    • Publications of The Korean Astronomical Society
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    • v.15 no.spc1
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    • pp.103-112
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    • 2000
  • Symbiotic stars are known as binary systems of a giant with heavy mass loss and a white dwarf accompanied by an emission nebula. They often show bipolar nebulae, and are believed to form an accretion disk around the white dwarf component by attracting the slow but heavy stellar wind around the giant companion. However, the existence and physical properties of the accretion disk in these systems still remain controversial. Unique to the spectra of symbiotic stars is the existence of the symbiotic bands around $6830{\AA}$ and $7088{\AA}$, which have been identified by Schmid (1989) as the Raman scattered features of the O VI $1032{\AA}$ and $1038{\AA}$ doublet by atomic hydrogen. Due to the incoherency of the Raman scattering, these features have very broad profiles and they are also strongly polarized. In the accretion disk emission model, it is expected that the Raman features are polarized perpendicular to the binary axis and show multiple peak structures in the profile, because the neutral scatterers located near the giant component views the accretion disk in the edge-on direction. Assuming the presence of scattering regions outflowing in the polar directions, we may explain the additional red wing or red peak structure, which is polarized parallel to the binary axis. We argue that in the accretion disk emission model it is predicted that the profile of the Raman feature around $6830{\AA}$ is different from the profile of the $7088{\AA}$ because the O VI line optical depth varies locally around the white dwarf component. We conclude that the Raman scattered features are an important tool to investigate the physical conditions and geometrical configuration of the accretion disk in a symbiotic star.

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Magnetic Circular Dichroism Study of co Thin Films on Pd(111) Surface

  • Kim, Wookje;Kim, Wondong;Kim, Hyunjo;Kim, Jae-Young;Hoon Kho;Park, J.H.;Oh, S.J.
    • Proceedings of the Korean Vacuum Society Conference
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    • 1999.07a
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    • pp.169-169
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    • 1999
  • We studied magnetic properties of co thin films deposited on Pd (111) surface, which attracted much attention recently due to the perpendicular magnetic anisotropy, using magnetic circular dichroism(MCD). Special attention was paid on the effect of Pd capping and interface roughness on the direction of magnetic easy axis, and for that purpose MCD signals for all Co thicknesses were measured with two different ways : in-plane and out-of-plane geometry. In case of bare Co films deposited on smooth Pd(111) surface, no MCD signal was observed under 4$\AA$ co thickness. At 4$\AA$ Co thickness, MCD signal at the out-of-plane geometry was observed, and for thicker Co films, only in-plane MCD signal was measured. This type of magnetic easy axis transition has been reported for other cases like Co/Pt system. The effect of 5$\AA$ Pd capping on these bare Co films made an remarkable change on the transition of magnetic easy axis. Out-of-plane MCD signals exists up to 20$\AA$ Co thickness, and disappears at 24$\AA$ Co thickness. In-plane MCD signals first appears at 10$\AA$ Co thickness and gradually increases up to 24$\AA$ Co thickness. Between 10$\AA$ and 20$\AA$ Co thickness, in-plane and out-of-plane MCD signal coexist. The formation of multi-domain structure or the existence of tilted magnetic easy axis is an possible scenario for such an interesting coexistence. The effect of interface roughness was also tested by measuring MCD signal on Co films deposited on un-annealed Pd(111) surface. Out-of-plane MCD signal was observed up to 8$\AA$ Co thickness and the anisotropy of MCD signal at 4$\AA$ Co thickness was very large with respect to that of Co film deposited on the smooth substrate. Above 8$\AA$ thickness, there exists only in-plane MCD signal. From above results, it was concluded that both Pd capping and interface roughness induce and reenforce the perpendicular magnetic anisotropy. The large perpendicular magnetic anisotropy of Co/Pd multilayer system made by sputtering method can be well understood from our results.

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