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Utility of CoaguChek XS for Monitoring the Prothrombin Time (프로트롬빈시간 모니터링을 위한 CoaguChek XS의 유용성)

  • Park, Rojin;Kim, Yong-Hyun;Kwon, Kyung Ock;Na, Jongsung;Won, Yong Soon;Sung, Ki Bum;Lee, Nae-Hee;Choi, Tae Youn;Shin, Jeong Won;Shin, Hee Bong;Lee, Yong-Wha;Lee, You Kyeong
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.6
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    • pp.471-475
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    • 2008
  • Background: In order to achieve a maintenance level and to prevent hemorrhagic complications, regular monitoring of the INR is mandatory for patients on oral anticoagulation therapy (OAT). A point-of-care instrument for INR monitoring is convenient for users, but the accuracy of the results has been controversial, and so this calls for exact evaluation of the point-of-care instrument that is used for INR monitoring. Methods: From Aug 2007 through Feb 2008, 85 patients on OAT among the all the patients who were admitted to Soonchunhyang University Bucheon Hospital were involved in this study. Parallel measurements of the PT INR were performed using a CoaguChek-XS and, a CA-7000 laboratory reference instrument and the results were analyzed. In addition, the patients' clinical data, including the diagnosis and the frequency and interval of the INR measurements, were also analyzed. Results: Of the 85 patients, 25 were admitted more than once to undergo INR testing and the mean interval between testing was 8.6 weeks with 39% and 38% of the tests being less than INR 2 units with using the CoaguChek-XS and the reference method, respectively. The coefficients of variation of CoaguChek-XS were 4.50 and 2.45 for the high and low INR patients, respectively. An excellent correlation was found between the two methods with a $R^2$ of 0.966 (p<0.001). Through Bland-Altman analysis, the mean INR difference between the two methods was 0.13 with the limit of agreement being -0.47~+0.72 with a 95% confidence interval. CoaguChek-XS was shown to overestimate the INR value for patients with an increasing INR, as compared to the reference method. Conclusion: CoaguChek-XS demonstrated great precision and accuracy for patients on OAT when compared to the laboratory INR results. Accordingly, the instrument should help to monitor the INR in the patients on OAT.

The Influence of Private Health Insurance on Admission among Some Patients with Cervical or Lumbar Sprain (민영의료보험 가입이 일부 경·요추부 염좌 환자의 입원에 미치는 영향)

  • Jang, Dong-Ryul;Kang, Myung-Geun
    • Journal of agricultural medicine and community health
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    • v.37 no.2
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    • pp.84-95
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    • 2012
  • Background: In Korea, private health insurance has neglected to induce externality on national health insurance by moral hazard. Therefore, we conducted this study in order to explore the influence of private health insurance on unnecessary medical utilization among patients with cervical or lumbar sprain. Method: The study examined a population of 449 patients (admission, 384; out-patient; 85) diagnosed with simple cervical or lumbar sprain without neurological symptoms at 20 small hospitals or clinics in Gwangju and Jeollanam provinces from Jul. 1 to Aug. 31 2008. The data were collected using structured, self-administrated questionnaire which collected information such as whether or not the patient was admitted (as a dependent variable), whether or not they had private health insurance (as a independent variable), and covariates such as socio-demographic characteristics, the factors related to the sprain, and characteristics of the insurance provider. Results: From hierarchical multiple logistic regression analysis, it was found that the admission rate of patient with private health insurance was higher than that those without it (Odds ratio=3.31, 95% Confidence interval; 1.14-9.58), meaning that private health insurance was an independent factor influencing the admission of patients with these conditions. Other determinants of admission were patient age and physician referral. Conclusions: This study is the first empirical study to explore the influence of private health insurance on inducing moral hazard in admission services, specifically among patients with cervical or lumbar sprain. Regulation of benefits provided by private health insurance may be necessary, as the effect of this moral hazard may mean existence of externality.

Factors Related to Psychosocial Stress and Fatigue Symptom Among Nurses Working at Ward and Operating Room in University Hospitals (대학병원 병동 및 수술실 근무 간호사의 사회심리적 스트레스와 피로수준에 관련된 요인)

  • Park, An-Sook;Son, Mi-Kyung;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.4
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    • pp.1781-1791
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    • 2013
  • The present study was intended to measure the level of psychosocial stress and fatigue symptom according to the various characteristics such as sociodemographic, health-related, job-related, job stress factors, and psychosocial factors among nurses working at ward and operating room in university hospitals, and to reveal the relation between these factors and psychosocial stress and fatigue symptom. The self-administered questionnaires were given to 220 nurses working at ward, and 147 nurses working at operating room in 4 participating hospitals located in Daejeon City during the period from July 1st to Aug 31st, 2012. As a results, the factors related to the psychosocial stress of nurses working at ward were age, subjective health status, job career, satisfaction of work, fit to the job, job demand, job control, coworker support, self-esteem, locus of control, type A behavior pattern. In operating room, there were age, sleep hours, subjective health status, job career, physical burden of work, satisfaction of work, fit to the job, consider quitting the job, job demand, job control, type A behavior pattern. The factors related to the fatigue symptoms of nurses working at ward were age, leisure time, subjective health status, satisfaction of work, consider quitting the job, job demand, locus of control, type A behavior pattern. In operating room, there were age, subjective health status, physical burden of work, supervisor support, coworker support, locus of control. Based on the study results, we suggest that the factors related to psychosocial stress and fatigue symptom of nurses were different from working station. We need development and application of programs to keep under management psychosocial stress and fatigue symptom.

A Clinical Study of Hypertrophic Pyloric Stenosis (비후성 유문 협착증의 임상적 고찰)

  • Kim, Yoon Hee;Jung, Myung Sup;Byun, Soon Ok
    • Clinical and Experimental Pediatrics
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    • v.45 no.11
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    • pp.1389-1396
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    • 2002
  • Purpose : This study was done to analyze the changes in the clinical conditions and the diagnosis of hypertrophic pyloric stenosis. Methods : We report a retrospective clinical analysis of 39 patients with hypertrophic pyloric stenosis from Jan. 1992 to Aug. 2001. The age and sex distribution, family and birth history, clinical symptoms, the ultrasonographic and the operative sizes of pyloric canals were compared. Results : The body weight was below the 3 percentile at admission in eight cases(20.5%). "Olive like mass" in right upper quadrant was palpated during physical examination in 23 cases(59%) and gastric peristaltic wave observed in six cases(15%). The ultrasonographic measurements showed that the pyloric muscle thickness to be $4.95{\pm}0.99mm$($mean{\pm}SD$), pyloric diameter $14.42{\pm}2.64mm$, and pyloric length $20.17{\pm}3.92mm$. Fredet-Ramstedt pyloromyotomy was employed in all cases. The operative measurements of the pyloric muscle thickness was $5.11{\pm}1.01mm$, pyloric diameter $15.01{\pm}2.47mm$, and pyloric length $22.32{\pm}3.43mm$. Conclusion : There was no significant difference between the ultrasonographic and operative measurements. Currently, the hypertrophic pyloric stenosis patients showed lesser clinical hallmarks of the disease. The earlier diagnosis using imaging studies before development of significant metabolic abnormalities is becoming an important factor that change the future outcomes of hypertrophic pyloric stenosis.

Effects of Submergency due to Heavy Rains on the Yield of Paddy (수도의 관수피해에 관한 조사연구)

  • Min-Shin Cho;Won-Sik Kim;Hoo-Seok Cheon;Jin-Gu Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.12
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    • pp.63-69
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    • 1972
  • There was a concentrated heavy rain resulted in 450mm of precipitation from Aug. 18 and 19, 1972. Almost all the paddy grown in the main plain areas of KimPo, Bu Cheon and Pyong Taek(N. L. $37^{\circ}$00'98'$-37^{\circ}$30'56", Long. $126^{\circ}$45'99"$-127^{\circ}$55'92"E) have been damaged of submergency. The effects of the different degrees of submergency in different growth stages of paddy, on the yield of paddy, rates of fertilization, maturity and degree of heading have been observed, and may be summarized as follows. (1) When the paddy was damaged due to submergency at the heading stage, a) on the basis of normal paddy, the yield of paddy may be expected about 67,57,40,9 and 6% with the submerged periods of 0.5, 1. 0, 2.0, 3.0 and 4.0 days, respectively, and a significant-negative correlation was found between the periods of submergency and the yields. b) As in the yield of paddy, rapid decreases in the rates of fertilizations and maturities of paddy were found as the submerged periods are increased. When the submerged periods are 0.5, 1.0, 2.0, 3.0 and 4.0 days, the corresponding rates of fertilizations and maturities observed are 89 and 88,83 and 78,52 and 40,24 and 19, and 12 and 9%, respectively, showing significant negrative correlations. c) Considerable decreases of the degree of heading were found as the submerged periods are increased. resulted in a significant negative correlation at 1% level between the degree of heading and submerged periods. (2) When the paddy plants were under submergency just before heading, the damage was found to be less than that at heading stage. The yields were 86,82,60,36 and 10%, as compared with the normal yield, with 0.5, 1.0, 2.0, 3.0 and 4.0 days of the submerged periods. (3) When the paddy was under the submergency at the mid-stage of head sprouting, its damage was severer than that of just before heading stage. The yields of paddy under the different submerged periods, 0.5, 1.0, 2.0, 3.0 and 4.0 days, were 79, 64, 34 and 6%, respectively, of the normal yields. normal yields.

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Effects of Dense Planting on the Growth and Producivity in Hot Pepper(Capsicum annum L.) (재식밀도(裁植密度)가 고추의 생육(生育) 및 생산성(生産性)에 미치는 영향(影響))

  • Kim, Kwang-Yong;Park, Sang-Keun;Lim, Sang-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.2 no.1
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    • pp.45-54
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    • 1983
  • This experiment was carried out to investigate effects of dense planting on the growth and productivity in varieties of hot pepper at open field. Three varieties (Joseng jinheung, Weonkyo No. 304 and Bulam house Putgochu) were sowed on Jan. 30th and transplanted on May 12th. The planting densities used were 3,300, 5,500 and 8,300 plants per 10a. The results obtained are as follows: 1) With higher plant density, the plant shape was changed from open-type to upright-type and the yield was increased, presumably due to the increase of leaf area index. 2) LAI and SLA per unit area were increased by denser planting. Wonkyo No. 304 presented the highest LAI and the lowest SLA. 3) Dry matter weight per unit area was also increased, however the LW/SW ratio was tended to decrease on denser planting. 4) Through crop growth analysis, it was determined that CGR and NAR were increased during the early growth stages and became decreased from last June. 5) Light intensity under the canopy formed by denser planting was decreased by 40% measured at 60 ㎝ above the soil surface. The vertical distribution of fruits became concentrated the upper part of plant. Fruit yield per unit area in denser planting was increased as compared to the conventional planting. The number of fruit setting decreased. 6) Generally, no differences in yield were detected in comparison between denser planting and conventional planting harvested on Aug. 30th and Oct. 15th, respectively. But Weonkyo No. 304 increased yield by 18% in denser planting.

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Effect of Sand Extraction on Meiobenthic Community of Jangbong-do in the Eastern Yellow Sea of Korea (서해 주문도 연안 사질 조하대에서의 해사채취가 중형저서동물 군집에 미치는 영향 연구)

  • Kang, Teawook;Min, Won-Gi;Hong, Jae-Sang;Kim, Dongsung
    • Korean Journal of Environmental Biology
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    • v.32 no.2
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    • pp.138-152
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    • 2014
  • The objective of the study survey was to determine the effect of marine sand extraction on community composition and rate of recolonization of the meiobenthos following cessation of mining activities. Because of meiobenthic distribution in nature, high abundance, intimate association with sediments, fast reproduction, benthic larva period, sensitivity to pollution and rapid life histories, meiobenthos are widely regarded as ideal organisms to study the potential ecological indicator of natural and anthropogenic stresses. The community structure of meiobenthos was studied at seven stations within sandy tidal and sub tidal zones in Jangbongdo in the Yellow Sea, Korea from Aug. 2006 to Dec. 2007. Meiobenthic samples were collected by three core samples, with a 3.6 cm in diameter, from each sediment sample taken with a Smith-McIntyre Grab. It was found that sand mining often causes complete removal of the sediment and the damage to the habitats of meiobenthos. This study in the effect showed that sand mining resulted in a reduction in total abundance and biomass of meiobenthos in mining area. The finding of this study further showed that initial restoration of abundance and biomass within one year of the cessation of sand mining.

Genotyping and Clinical study of Mycoplasma pneumoniae During 1996-1997 in Korea (1996년과 1997년 소아에서 유행한 Mycoplasma pneumoniae의 Genotype에 따른 임상적 연구)

  • Lim, Hong Hee;Ahn, Byung Moon;Kim, Eun Ryoung;Choi, Sug Ho;Moon, Young Ho;Kim, Il Soo
    • Pediatric Infection and Vaccine
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    • v.5 no.1
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    • pp.79-87
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    • 1998
  • Purpose : The P1 protein of Mycoplasma pneumoniae mediates the attachment of the pathogen to its host cell and elicits a strong humoral immune response during infection with this organism. Mycoplasma pneumoniae strains can be classified into two groups(I and II) by PCR method of P1 cytadhesin gene. In this study, we evaluated the prevalence, epidemiological and clinical characteristics of each group. Methods : From 155 patients with Mycoplasma pneumoniae, who admitted to the Department of Pediatrics, Sung-Ae and Kwangmyung Sung-Ae Hospital between November 1996 and October 1997, we collected their throat swabs or nasopharyngeal aspirates for DNA extraction and serum for indirect hemagglutination test of Mycoplasma pneumoniae. The group specific PCR amplification were performed using specific oligonucleotide primers designed for P1 gene genotyping. Results : Group I(137 patients, 88.4%) occurred frequently than group II(18 patients, 11.6%). In both group, the most prevalent season was winter in 1996(Nov. to Dec.) and fall in 1997(Aug. to Oct.) The prevalent age was four to six years old. The number of male was more than female in both group; Group 1(1.2:1), Goup 2(1.6:1). No significant relationship were found between two groups in duration of fever and hospital days(P>0.05). The rate of high antibody titers(>1:5120) was lower in group I(6/137, 4.4%) than group II(2/18, 11.1%). Conclusion : Group I was much more prevalent than group II during 1996~1997 in Korea. There was no difference between two groups in epidemiological and clinical parameters except the rate of high antibody titers. Further follow-up survey will be needed for the epidemiologic and clinical studies of Mycoplasma pneumoniae in Korea.

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Pulmonary Complications after Surgery for Esophageal Cancer (식도암 수술 후 발생한 호흡기 합병증)

  • Lee, Jang-Hoon;Lee, Jung-Cheul
    • Journal of Chest Surgery
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    • v.39 no.2 s.259
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    • pp.134-139
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    • 2006
  • Background: Complications after surgery for esophageal cancer are various and not rare. Among them, pulmonary complication is well known as one of the most important insults which has negative influence on the postoperative course and results in mortality. So we attempted to analyze the factors which may have relation to postoperative pulmonary complication. Material and Method: The retrospective study was undertaken in 87 patients who underwent curative surgery for esophageal cancer from Jan. 1996 to Aug. 2005. We divided them into two groups, patients with pulmonary complication (group A, n=28), without pulmonary complication (group B, n=59). Statistical analysis was performed with Fisher's exact test. Result: The postoperative pulmonary complication developed in 28 patients ($32\%$). There was no difference between two groups in past medical history, preoperative pulmonary function, surgery time, anastomosis method, pathologic stage, and trial of neoadjuvant therapy. Age and incidence of cervical anastomosis were significantly higher in group A (p=0.001, p=0.023). The rate of routine postoperative ventilator care was significantly higher in group S (p=0.007). Chest tube indwelling time and hospital stay were significantly longer in group A (p=0.011, p=0.001). There were 6 postoperative deaths ($6.8\%$) and 5 deaths were related to pulmonary complication. Pneumonia was the most common cause of death and MRSA (methicillin resistant staphylococcus aureus) was the most common organism in sputum culture. Conclusion: Pulmonary complication after esophageal cancer surgery was the most important cause of death. Pulmonary complication was closely related to patient's age and cervical anastomosis. We think postoperative routine ventilator care is helpful for prevention of pulmonary complications, especially MRSA pneumonia, and reducing mortality.

Studies on the grassland Development in the Forest V. Effect of sharing degrees on the early growth characteristics and winter survival of main grasses (임간초지 개발에 관한 연구 V. 차광정도가 주요 초목의 초기생육과 월동에 미치는 영향)

  • Park, M.S.;Seo, S.;Han, Y.C.;Lee, J.Y.
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.6 no.1
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    • pp.38-43
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    • 1986
  • This field experiment was conducted to determine the effects of shading degrees (0 : full sunlight, 25, 50 and 75%) on the early growth characteristics and winter survival of grasses. For the test different artificial shading houses were established and pasture species used were orchardgrass, timothy and perennial ryegrass. The experiment was performed at Livestock Experiment Station in Suweon, and sowing date was Aug. 25, 1984. The results are summarized as follows : 1. Generally, root length, new root length, number of new root and tillers of grasses were increased at 0% (full sunlight) of shading, followed by 25, 50 and 75% of shading degrees, in that order. Plant length and leaf elongation, however were increased at 50% of shading, followed by 75, 25 and 0%. 2. The percentage of winter killing of grasses was significantly (P<0.05) increased as the shading degrees increased. Also the percentages of winter killing were 10.1% in orchardgrass, 9.5% in timothy and 14.2% in perennial ryegrass, respectively. 3. A significant negative correlations were observed in the relationship between winter killing and tillers, new root length and number of new root of grasses. However, there were positive correlations between winter killing and plant length or leaf elongation under shading conditions. 4. As the shading degrees are increased by 0, 25, 50 and 75%, the NAR of grasses was tended to be decrease to 10.98, 11.52, 9.81 and 6.12 g/$m^2$/day, in that order. Also there was a negative correlation (r=-0.5943*) between winter killing and NAR of grasses, and NAR of orchardgrass, timothy and perennial ryegrass were 8.58, 8.53 and 11.71 g/$m^2$/day, respectively.

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