• Journal of Korea Spatial Information System Society
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• v.12 no.1
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• pp.100-104
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• 2010

Recently with advent of Web 2.0, RESTful Web Services are becoming increasing trend to emphasize Web as platform. There are already many services and the number of service increases in very fast pace. So it is difficult to find the service what we want by keyword based search. To solve this problem, we developed the search method using sem antic technologies about RESTful Web Services. For that, first we define the system structure and model the description format based on the integrated search system for OpenAPIs, and then we add Semantic Markup (tagging, semantic annotation) on the HTML description pages. Next we extract RDF document from them and store it in service repository. Based on the keywords that are extended by means of ontology, the developed system provides more purified and extended results than similarity-based keyword searching system.

• Journal of Technology Innovation
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• v.20 no.2
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• pp.135-159
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• 2012

To the analysis and discussion whether to conceptualization between the basis and LCM(Life cycle management) of patentability decisions and evergreening through research on patent application strategies and litigation cases. The Stakeholders have said that the LCM and evergreening strategies are an innovative effort to develop new pharmaceuticals, while others say that it is an effort to block generic pharmaceuticals from entering the market and permanently dominate the market by generic pharmaceuticals manufacturers or health economic perspectives. To achieve the goal of research, to discuss for conceptualization LCM and Evergreening strategies through patent application strategies for 14 pharmaceuticals for APIs and case studies for litigations. As a results, the LCM is getting patent rights for the results of research at the initial R&D stage and as such this shall be regarded as part of an effort for technology innovation. However, Evergreening is granting patent rights for the results by making high permission barrier to prevent the market entry of generic pharmaceuticals in the late development period during the pharmaceuticals development process or after their launch. This may lead to the problem of getting weak in health economic aspects and consumer welfare aspects by lowering the market accessibility of cheap generic pharmaceuticals.

• Korean Journal of Veterinary Service
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• v.39 no.2
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• pp.81-86
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• 2016

Honeybee venom (BV) from Apis mellifera L. has been used as natural antimicrobial compounds in pigs, cows, dairy cattle and chicken farms in Korea. The purpose of this study was conducted to confirm homogeneity and stability of BV dissolved with distilled water or saline solution. Melittin was analyzed with ultra-high performance liquid chromatography (UPLC) for BV to secure the validation of analysis. BV at concentration of 1 mg/mL was dissolved with distilled water or saline solution at room temperature. Homogeneity of BV dissolved with distilled water or saline solution at upper, milddle, and lower layers all satisfied the accuracy and precision criteria. Stability of BV dissolved with distilled water or saline solution for 7 days all satisfied the criterion both light and dark storage condition. BV has satisfied with homogeneity and stability in distilled water or saline solution at room temperature under light or dark condition. The results of this study suggest that BV has a possibility as the substitute of natural antimicrobial agents for the animal drugs and feed additives.

• Journal of KIISE:Software and Applications
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• v.29 no.4
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• pp.225-234
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• 2002

The developers of mobile agent systems are considering integrating the system into the web and the developers of web servers are also considering supporting mobile agents in the future. But they are not clearly suggesting the relationship between web programming which has basically client/server architecture and mobile agent programming which is based on autonomous code mobility. In this paper, firstly, we clarify the method for integrating mobile agent programming into web programming by suggesting the model for mobile agent programming on the web. Secondly, by developing APIs for Java which is widely used for both web programming and mobile agent programming, we made it possible for programmers to use them for programming mobile agent on the web. Thirdly, we show the usefulness of the proposed model by adding and testing modules for execution environment of mobile agents on W3C's Java based web server, Jigsaw.

• Journal of KIISE:Computing Practices and Letters
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• v.7 no.5
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• pp.539-547
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• 2001

Cluster systems employ high speed interconnection networks and use efficient communication layers to gain high performance and scalability. But the diversity in implementation mechanism among these communication layers causes lack of portability. A solution is to provide communication standard APIs such as MPI. This paper introduces MPI-VMMC: an MPI implementation on VMMC. Though the direct deposit transfer mechanism used in VMMC is not suitable for Send/Recv mechanism used in MPI, the proposed sub-layer laid between MPI and VMMC efficiently translates from one mechanism to the other. We also use the lazy pointer and selective zero-copy transfer technique to gain high performance. The peak performance of MPI-VMMC is 90.7Mbytes/sec, which is about 95% of the base communication layer\`s.

• Journal of Pharmacopuncture
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• v.21 no.2
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• pp.126-131
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• 2018

This study investigates the effect of a combination of homeopathic medicine and electro- acupuncture in two patients with breast cancer and severe liver disease who could not receive standard anaesthesia therapy due to liver problems. Specifically, measurable and quantifiable parameters were used to evaluate whether an integrated approach-consisting of electro- acupuncture and a homeopathic medicine diluted above Avogadro's limit (that is, above a potency of 12CH) during the pre-surgical, surgical and post-surgical phases -can improve general well-being of a patient undergoing breast cancer surgery. In breast cancer surgery, we employed an integrated approach consisting of induction with hypnotics and muscle relaxants, followed by maintenance with anaesthetic gas, combined with a homeopathic treatment (Arnica montana 15CH and Apis mellifica 15CH) before and after surgery and an electro- acupuncture treatment performed in the pre- and post-surgical phases without any analgesic/pain relieving medications. Both of the patients treated with the integrated approach improved their overall condition without need for other common pain relieving medicines. Additionally, thanks to their rapid awakening, the patients were not relocated to a protected area and the hospitalization was shorter. A multidisciplinary approach incorporating homeopathic medicine and electro-acupuncture can be a solution for patients who need or ask about a different and/or safer alternative to the standard treatment. This approach can offer a safe, much less expensive, non-invasive and viable alternative for such cases. Moreover it can be useful for an opioids free anesthesia.

• The Journal of the Korea Contents Association
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• v.15 no.11
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• pp.571-581
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• 2015

In the field of Korean medicine (KM), KM terms has been mixed used for a long period. After the Society of KM had systematically organized the KM terms used in our country, the book for the Korean medical standard terminologies was published. In this study, we developed an online service based on the book. The online service provides various useful functions for searching the terms and their commentary and collecting users' opinions. Users can also compare the standard terms with their semantic search results and naver's knowledge search results within our system. By analyzing logs of our system, we suggested several directions for future development, including the improvement of search functions, advertisements, and the provision of open APIs. In the future, our online service might provide the important information on clinics, academic researches, and international standards.

• Journal of Microbiology and Biotechnology
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• v.24 no.7
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• pp.888-897
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• 2014

A bacterial community analysis of the gut of Tenebrio molitor larvae was performed using pyrosequencing of the 16S rRNA gene. A predominance of genus Spiroplasma species in phylum Tenericutes was observed in the gut samples, but there was variation found in the community composition between T. molitor individuals. The gut bacteria community structure was not significantly affected by the presence of antibiotics or by the exposure of T. molitor larvae to a highly diverse soil bacteria community. A negative relationship was identified between bacterial diversity and ampicillin concentration; however, no negative relationship was identified with the addition of kanamycin. Ampicillin treatment resulted in a reduction in the bacterial community size, estimated using the 16S rRNA gene copy number. A detailed phylogenetic analysis indicated that the Spiroplasma-associated sequences originating from the T. molitor larvae were distinct from previously identified Spiroplasma type species, implying the presence of novel Spiroplasma species. Some Spiroplasma species are known to be insect pathogens; however, the T. molitor larvae did not experience any harmful effects arising from the presence of Spiroplasma species, indicating that Spiroplasma in the gut of T. molitor larvae do not act as a pathogen to the host. A comparison with the bacterial communities found in other insects (Apis and Solenopsis) showed that the Spiroplasma species found in this study were specific to T. molitor.

• Korean Journal of Veterinary Service
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• v.31 no.2
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• pp.229-237
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• 2008

This study was conducted to evaluate the effect of honeybee venom, purified using bee venom collector, and feeding of probiotics on the body weight gain, growth rate and hematological characteristics of pigs. A total of 120 pigs were examined and divided into 4 groups 1) Control (basal diet), 2) BV (basal diet + bee venom), 3) PB (basal diet + probiotics), 4) BVPB (basal diet + BV + PB). Average daily weight gain improved significantly in all test groups, especially BVPB (P < 0.05) compared to the controls. There was a significant difference in the feed conversion rate (P < 0.05) and efficiency (P < 0.05) between BVPB and control pigs. Weight gain and survivability was higher in the tests than the controls, but white blood cell count was not. Serum total protein, albumin and IgG concentration of BVPB were slightly higher than those of controls. These results suggest that treated honeybee venom and probiotics should be used together to effectively increase the productivity of pigs.

• Journal of Korea Game Society
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• v.14 no.5
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• pp.117-126
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• 2014

There are various kinds of applications if one can develop a remote execution system using for legacy 3D APIs. It can be used in implementing a cloud gaming service based on the real-time video streaming technology. Or, it can also be used in implementing a GPU virtualization for simultaneously rendering of many different 3D applications. The OpenGL API consists of independent global functions while the Direct3D API consists of Microsoft COM-based interfaces and their member functions, which makes the implementation of remote rendering system more difficult. The purpose of the paper is to show the applicability of the technology to any legacy 3D API by successfully designing and implementing a remote rendering system using the Direct3D API. It applies the implementation to a sample Direct3D application and also performs a few experimentations to show the technical feasibility.