• Korean Journal of Food Science and Technology
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• v.44 no.6
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• pp.653-657
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• 2012

While it is known that sulfur containing amino acids (SCAA) are very important in regulating hepatocyte growth and preventing liver-diseases, the fundamental molecular mechanisms of how they exert their hepatoprotective functions are not well known. Since it is widely understood that the hepatic concentrations of S-adenosylmethionine (SAMe) in chronic liver disease patients are severely decreased, the pathophysiological importance of SAMe and its downstream antioxidant, glutathione should be discussed in order to see a big picture of relationship between SCAA and liver diseases. Chronic SAMe deficient mice have shown spontaneous hepatocellular carcinoma development due to impaired mitochondria functions with low levels of prohibitin1 protein, and through deficiency in many genes which are known to ameliorate genetic instability, such as APEX1 and DUSP1, the functions of which are recovered by SAMe treatment. In this review, current knowledge of the basic concepts of the mechanisms through which SCAAs protect the liver will be discussed in detail. Also, a possible tumor suppressor in livers, prohibitin1, and its functional relationship with SAMe will be discussed.

• Korean Journal of Medicinal Crop Science
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• v.13 no.6
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• pp.273-277
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• 2005

Adventitious shoots were directly induced from leaf explants of R. glutinosa, an important medicinal plant. Proliferating shoot cultures were obtained by culturing leaf discs on Murashige and Skoog(MS) medium alone or combination with auxins and cytokinins. MS medium supplemented with 1 $mg/{\ell}\;BA\;and\;2\;mg/{\ell}$ IAA was the most effective, providing high shoot bud formation frequency without formation of intervening callus. The effect of leaf age on adventitious shoot formation was also investigated. The maximum shoot bud production (93.4%) was achived using 3rd leaf from apex of 6 weeks old plantlets after seed germination. Plantlet were rooted on an half-strength MS (1/2MS) medium containing 0.1 $mg/{\ell}\;IBA$. This prtocol is useful for clonal propagation and Agrobacterium-mediated transforamtion in R. glutinosa.

• Journal of Microbiology
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• v.37 no.1
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• pp.27-34
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• 1999

Two fractions with unusual antifungal activity that suppress asexual sporulation of several fungi were obtained from culture filtrate of Pseudomonas aeruginosa and were partially purified through the repeated silicagel flash column chromatographies. The sporulation-suppressive actions of these fractions in Aspergillus nidulans, Rhizopus stolonifer, and Coprinus cinereus, were analyzed by light and electron microscopes. The germination ability of the spores produced in the presence of these fractions were also checked to determine the persistent effects of these antifungal substances on the next generation. Light microscopic observation of developing sporangia of R. stolonifer grown in the presence of both fractions revealed that the significant number of sporangia failed to reach maturity, and frequently, uncontrolled growths of hyphae and rhizoids from the sporangiophores were found. In A. nidulans addition of these fractions appeared to cause different classes of morphological abnormality in conidia development, which included aborted formation of conidiogenous cells from the apex of conidiophores and enhanced hyphal growths either at the tip or middle of the conidiophores. Germination abilities of spores obtained from the cultures grown in the presence of antifungal fractions were 40∼60% in Aspergillus, 50∼80% in Coprinus (thallic spores), and 30∼40% in Rhizopus compared to those of normal spores.

• Restorative Dentistry and Endodontics
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• v.43 no.2
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• pp.15.1-15.7
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• 2018

Objectives: The present study aimed to evaluate the shaping ability of 2 thermally treated nickel-titanium reciprocating systems in simulated curved canals. Materials and Methods: Forty simulated canals were prepared to apical size 25 using Reciproc Blue R25 (VDW) and WaveOne Gold Primary (Dentsply Sirona) instruments. Standard pre- and post-preparation images were taken and superimposed. The removal of resin material was measured at 5 standard points: the canal orifice, halfway between the canal orifice and the beginning of the curve, the beginning of the curve, the apex of the curve, and the end-point of the simulated canal. The data were analysed using the independent sample t-test with a 5% significance threshold. Results: The canals in which Reciproc Blue R25 was used showed a significantly greater widening than those in which WaveOne Gold was used at 4 of the 5 measurement points (p < 0.05). The Reciproc Blue R25 instrument removed significantly more resin from the inner aspect of the curve at 2 of the 5 points and similar amounts at the remaining 3 points. At the 2 apical points, there was no significant difference between the Reciproc Blue R25 and WaveOne Gold Primary instruments. Conclusion: Both instruments respected the original canal anatomy; however, WaveOne Gold resulted in a more conservative shape with less transportation.

• Restorative Dentistry and Endodontics
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• v.45 no.3
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• pp.29.1-29.9
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• 2020

This study describes the clinical steps taken in the treatment of a patient who had an avulsed right upper central incisor that presented with incomplete root development and chronic apical periodontitis. A 7-year-old boy was referred from a private dentist to a dental office specializing in endodontics. The tooth had remained in a dry environment for 20 minutes, and tooth replantation was performed at an emergency appointment. After clinical and radiographic examinations, root canal decontamination was performed, followed by several changes in intracanal calcium hydroxide medication. Blood clot formation was attempted, but bleeding within the root canal was insufficient; therefore, we opted for an intracanal medication change to stimulate mineralized tissue formation in the apical region. Root obturation was performed 45 days after the last change of intracanal medication, and clinical, radiographic, and tomographic follow-up examinations were performed at 3, 6, 18, and 40 months after the endodontic intervention. The increase in thickness and length of the root structure and the absence of root resorption were verified through follow-up examinations. Therefore, it was concluded that the procedures used were successful for tooth replantation.

• Journal of Information Science Theory and Practice
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• v.2 no.1
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• pp.62-70
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• 2014

The All India Council for Technical Education (AICTE), an apex body of controlling technical education in India, has made mandatory subscription of e-Resources to all its Engineering College Libraries. This policy has directly helped the teaching community, research scholars, and student's paternity, which has benefits for their teaching, research activities, and curriculum, respectively. This study emphasizes the usefulness of e-Resources among the teachers and scholars of engineering colleges in the Bangalore region under Visvesvaraya Technological University (VTU), Belgaum, Karnataka. Survey methodology has been used as the basic research tool for data collection with the help of questionnaires. 866 teaching faculties in VTU were selected randomly on the basis of willingness of users who access the e-Resources for their academic and research activities in the survey. The survey results were tabulated and analyzed with descriptive statistics methods using the SPSS 20 software package. The findings reveal that e-resources are useful for engineering college teachers and scholars for their academic and research activities.

• Restorative Dentistry and Endodontics
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• v.7 no.1
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• pp.41-45
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• 1981

A 19-year-old Korean woman presented with left mandibular dental pain and swelling. Periapical radiolucencies were associated with the mandibular left first molar, second molar and the mandibular right second molar. The mandibular right second molar root developed incompletely and has the open apex. Clinical examination revealed worn accessory occlusal cusps of premolars. A diagnosis of dens evaginatus with associated periapical lesion secondary to pulpal necrosis was made. The root canal of the lower right second premolar was sealed with Calcium hydroxide paste for apexification. About two months later Calcium hydroxide paste was removed and the canal was resealed with new Calcium hydroxide paste. After four months the canal was sealed permanently with guttapercha and zinc oxide-eugenol sealer. The root canals of the lower left premolars were irrigated every week with 3.5% NaOCl solution for and half month. And the canals were sealed with gutta-percha and ZOE sealer. Preventive endodontic treatment for the lower right first premolar was undertaken.

• Restorative Dentistry and Endodontics
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• v.40 no.2
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• pp.143-148
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• 2015

Objectives: This study evaluated the maximum depth and percentage of irrigant penetration into dentinal tubules by passive ultrasonic irrigation (PUI). Materials and Methods: Thirty extracted human teeth were instrumented and divided into three groups. According to final irrigation regimen, 5.25% sodium hypochlorite (Group A, NaOCl), 2% chlorhexidine (Group B, CHX) and saline solution (Group C, control group) were applied with Irrisafe 20 tips (Acteon) and PUI. Irrigant was mixed with 0.1% rhodamine B. Sections at 2 mm, 5 mm, and 8 mm from the apex were examined with confocal laser scanning microscopy (CLSM). The percentage and maximum depth of irrigant penetration were measured. Kruskal-Wallis test and Mann-Whitney test were performed for overall comparison between groups at each level and for pairwise comparison, respectively. Within a group, Wilcoxon test was performed among different levels. p values less than 0.05 were considered significant. Results: In all groups, highest penetration depth and percentage of penetration were observed at the 8 mm level. At 2 mm level, Groups A and B had significantly greater depths and percentages in penetration than Group C (p < 0.05), but there were no significant differences between Groups A and B. At 5 mm level, penetration depths and percentage of penetration was not significantly different among the groups. Conclusions: NaOCl and CHX applied by PUI showed similar depth and percentage of penetration at all evaluated levels.

• Journal of radiological science and technology
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• v.41 no.1
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• pp.1-6
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• 2018

The purpose of this study is to provide baseline data on lung field size measured radiological method by chest PA image in normal Korean. The subject of this study is 496 normal persons who performed chest PA examination using x-ray digital radiography system. The measurement method is from the apex of right and left lung to the costophrenic angle of both lung, from the top of the image to the lowest costophrenic angle of both lung and transverse line of the largest lung area. As a result of this study, the following conclusions were obtained. A lung field size of male is larger than the female(p<0.05). The younger the age, the longer both lung length and total lung height statistically significant. As a increase height and length, A lung field size was increased(p<0.05). But, BMI is not associated with a lung field size. This study will be data of reference data when radiological technologists perform chest PA examination.

• Korean Journal Plant Pathology
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• v.14 no.2
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• pp.115-119
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• 1998

Root rot of carnation caused by isolates of Phytophthora was found at Kongju, 1996. Infected plants appeared symptoms of wilting, brown discoloration on collar area and consequently led to death. The causal pathogen was identified as Phytophthora nicotianae based on morphological, cultural and physiological characteristics. Mycelium was grown to rosette colony pattern on corn meal agar and the growth was 10.2 mm/day on 10% clarified V8 medium at $25^{\circ}C$. Swelling with radiating hyphae was formed in water and on agar within 7 days. Chlamydospores were abundantly produced on agar within 7 days. Sporangium was prominent papillate, 2~3 apex, 1.2 : 1 l/b ratio, lateral attacment on sporangiospore and was rarely produced on solid media but produced in water. The shape of sporangium was spherical or ovoid, and the size was 34~73$\times$32~60 (av. 33$\times$66.5) ${\mu}{\textrm}{m}$ in dimension. The isolates were heterothallic, and mating type A2. Oogonium was spherical, ovoid, 26~36 (av. 36 ${\mu}{\textrm}{m}$) in diameter, and antheridium was amphygynious to oogonia. The fungus was able to grow 10~35$^{\circ}C$, and optimal temperature was 27$^{\circ}C$.