• Title/Summary/Keyword: AP-3

Search Result 1,505, Processing Time 0.022 seconds

Spin-polarized Current Switching of Co/Cu/Py Pac-man type II Spin-valve

  • Lyle, Andrew;Hong, Yang-Ki;Choi, Byoung-Chul;Abo, Gavin;Bae, Seok;Jalli, Jeevan;Lee, Jae-Jin;Park, Mun-Hyoun;Syslo, Ryan
    • Journal of Magnetics
    • /
    • v.15 no.3
    • /
    • pp.103-107
    • /
    • 2010
  • We investigated spin-polarized current switching of Pac-man type II (PM-II) nanoelements in Pac-man shaped nanoscale spin-valves (Co/Cu/Py) using micromagnetic simulations. The effects of slot angle and antiferromagnetic (AFM) layer were simulated to obtain optimum switching in less than 2 ns. At a critical slot angle of $105^{\circ}$, the lowest current density for anti-parallel to parallel (AP-P) switching was observed due to no vortex or antivortex formation during the magnetic reversal process. All other slot angles for AP-P formed a vortex or antivortex during the magnetization reversal process. Additionally, a vortex or anti-vortex formed for all slot angles for parallel to anti-parallel (P-AP) switching. The addition of an AFM layer caused the current density to decrease significantly for AP-P and P-AP at slot angles less than $90^{\circ}$. However, at slot angles greater than $90^{\circ}$, the current density tended to decrease by less amounts or actually increased slightly as shape anisotropy became more dominant. This allowed ultra-fast switching with 5.05 and $5.65{\times}10^8\;A/cm^2$ current densities for AP-P and P-AP, respectively, at a slot angle of $105^{\circ}$.

Study on the Enhancement of Burning Rate of HTPB/AP Solid Propellants (HTPB/AP계 고체 추진제의 연소속도 증진 방안 연구)

  • Lee, Sunyoung;Ryu, Taeha;Hong, Myungpyo;Lee, Hyoungjin
    • Journal of the Korean Society of Propulsion Engineers
    • /
    • v.21 no.4
    • /
    • pp.21-27
    • /
    • 2017
  • In this paper, in order to control the burning rate and pressure exponent of HTPB/AP/Al based propellant for the improvement of performance, the effect of the size ratio of AP particles and various contents of Butacene as burning catalyst on combustion properties was investigated. In the propellant formulation with both $28{\mu}m$ Al of 23% and Butacene of 3%, the burning rate and pressure exponent were increased with increasing the contents of $9{\mu}m$ AP particles. And the burning rate was increased with increasing the contents of Butacene with showing the relatively low pressure exponent in the propellant containing Butacene. However, the significant variations of pressure exponent by contents of Butacene were not observed.

Conversion of Gycosylphosphatidylinositol (GPI)-Anchored Alkaline Phosphatase by GPI-PLD

  • Moon, Young-Girl;Lee, Hyun-Jung;Kim, Mee-Ree;Myung, Pyung-Keun;Park, Soo-Young;Sok, Dai-Eun
    • Archives of Pharmacal Research
    • /
    • v.22 no.3
    • /
    • pp.249-254
    • /
    • 1999
  • Enzymatic conversion of brain glycosylphosphatidylinositol-linked alkaline phosphatase (GPI-AP), amphiphilic, was examined. When GPI-AP was incubated with glycosylphosphatidylinositol-specific phospholipase D (GPI-PLD), a negligible conversion of GPI-AP to hydrophilic form was observed. The inclusion of monoacylglycerols enhanced the enzymatic conversion, although the action of monoacylglycerols differed greatly according to the size of acyl group; the enzymatic conversion was enhanced considerably in the presence of monoacylglycerols possessing acyl group of longer chain length ($C_{10-}C_{18}$), which monoacylglycerols with acyl moiety of shorter length ($C_{4-}C_{8}$) did fail to augment the enzymatic conversion. Noteworthy, monooleoylglycerol was much more effective than the other monoacylglycerols in promoting the enzymatic conversion, indicating a beneficial role of the unsaturation in acyl chain. Meanwhile, ionic amphiphiles such as monohexadecyllysophosphatidylcholoine and palmitoyl-carnitine decreased the enzymatic conversion of GPI-AP in a concentration-dependent manner, with monohexadecyllysophosphatidylcholine and palmitoyl-carnitine deceased the enzymatic conversion of GPI-AP in a concentration-dependent manner, with monohexadecyllysophosphatidylcholoine being more inhibitory than palmitoylcarnitine. Separately when GPI-AP was exposed to various oxidants prior to the incubation with GPI-PLD, a remarkable decrease of the enzymatic conversion was observed with hypochlorite and peroynitrite generators, but not $H_{2}O_{2}$. In further study, hypochlorite was found to inactivate GPI-PLD at low concentrations ($3~100{\mu}M$). From these results, it is suggested that the enzymatic conversion of GPI-AP by GPI-PLD may be regulated in vivo system.

  • PDF

Preparation and Release Properties of Acetaminophen Imprinted Functional Starch based Biomaterials for Transdermal Drug Delivery (경피약물전달을 위한 아세트아미노펜 각인 기능성 전분 기반 바이오 소재 제조 및 방출 특성)

  • Kim, Han-Seong;Kim, Kyeong-Jung;Lee, Si-Yeon;Cho, Eun-Bi;Kang, Hyun-Wook;Yoon, Soon-Do
    • Applied Chemistry for Engineering
    • /
    • v.32 no.3
    • /
    • pp.299-304
    • /
    • 2021
  • This study focuses on the preparation of acetaminophen (AP) imprinted functional biomaterials for a transdermal drug delivery using mung bean starch (MBS), polyvinyl alcohol (PVA), sodium benzoate (S) as a crosslinking agent, glycerol (GL) as a plasticizer, and melanin (MEL) as a photothermal agent. The prepared AP imprinted biomaterials were characterized using FE-SEM and their physical properties were evaluated. The photothermal effect and AP release property for functional biomaterials were examined with the irradiation of near infrared (NIR) laser (1.5 W/cm2). When the NIR laser was irradiated on functional biomaterials with/without the addition of MEL, the temperature of MEL added biomaterial increased from 25 ℃ to 41 ℃, whereas the biomaterial without MEL increased from 25 ℃ to 28 ℃. Results indicate that there is the photothermal effect of prepared biomaterial with the addition of MEL. Based on the results, AP release properties were evaluated using standard buffer solutions and artificial skin. It was found that AP release rates of MEL added AP loaded biomaterials were 1.2 times faster than those of MEL non-added AP loaded biomaterials when irradiating with NIR laser. We envision that the developed functional biomaterials can be utilized for an acute pain-killing treatment.

Antiinflammatory and antioxidative effects of Agrimonia pilosa Ledeb

  • Sim, SY;Kim, GJ;Ko, SG
    • Advances in Traditional Medicine
    • /
    • v.7 no.3
    • /
    • pp.217-228
    • /
    • 2007
  • Agrimonia pilosa Ledeb. has long been used for a useful natural agent ameliorating inflammation related symptoms in the folk medicine recipe. This study was performed to investigate effects of Agrimonia pilosa Ledeb.(AP) on the expression of inflammation related genes such as the inducible nitric oxide synthase (iNOS) in macrophage cell line, RAW 264.7 cells. The AP (whole plants) was extracted with 80% ethanol and sequentially partitioned with solvents in order to increase polarity. Among the various solvent extracts of AP, the n-butanol (BuOH) fraction showed the most powerful inhibitory ability against nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW 264.7 cells without affecting cell viability. Reverse transcriptase-polymerase chain reaction and Western blot analysis revealed that the BuOH fraction provided a primary inhibitor of the iNOS protein and mRNA expression in LPS-induced RAW 264.7 cells. The DPPH and OH radical scavenging activities of the several fractions of 80% ethanol extracts of AP significantly increased by EtOAC and BuOH fractions. Thus, the present study suggests that the response of a component of the BuOH fraction to NO generation via iNOS expression provide an important clue to elucidate anti-inflammatory mechanism of AP.

A Study on Properties of HTPB/AP/Al Propellant to Contents of Bonding Agents (결합제 함량에 따른 HTPB/AP/Al 추진제의 특성 연구)

  • Lee, Youngwoo;Ha, Sura;Jang, Myungwook;Kim, Taekyu;Lee, Jungjoon;Son, Hyunil
    • Journal of the Korean Society of Combustion
    • /
    • v.22 no.3
    • /
    • pp.47-52
    • /
    • 2017
  • The propellant tile and crack which account for the greatest proportion of solid rockets are profoundly affected by viscosity and mechanical properties of solid propellant. In this paper HTPB/AP/Al system propellant has been researched for the viscosity, mechanical properties and burning properties with type and contents of bonding agents. The viscosity of propellant was changed significantly depending on the type and contents of bonding agents, and mechanical properties of HTPB/AP/Al system propellant were also varied. Considering both lower viscosity and stable mechanical properties, the optimum type and contents of bonding agents can be identified as the main factors to the HTPB/AP/Al system propellant.

A Clinical Case Report on the Malalignment Treated by Chuna Manual Therapy - Based on the Full Spine AP X-ray and VAS - (추나치료를 이용한 골반, 척추 및 견갑대 부정렬의 치험 3례 - Full spine AP X-ray, VAS 분석에 따른 -)

  • Park, Ji-Hyun;Jeong, Hyun-A;Hong, Seo-Young
    • The Journal of Churna Manual Medicine for Spine and Nerves
    • /
    • v.5 no.2
    • /
    • pp.135-149
    • /
    • 2010
  • Objectives : This study was designed to observe the effect of Chuna manual therapy on the asymmetrical alignment. Methods : To analyze static structural alignment, posterior inferior ilium deviation(PI), inflare change of pelvis were checked from full spine AP X-ray. And Cobb's angle of spine and height of shoulder girdle were analyzed. To evaluate the pain visual analogue score(VAS) was scored. Chuna therapy treated 8-10 times for 1 month. Results and Conclusions : In 3 cases, VAS was improved significantly. Full spine AP X-ray shows improvement of structural imbalace. Shoulder height difference, cobb's angle, pelvic insufficiency improved considerably. These results suggest that Chuna therapy might be effective for malalignment patients.

  • PDF

A STUDY ON THE EFFECT OF POLYMERIZATION SHRINKAGE OF SEVERAL COMPOSITE RESIN USING STRAIN GAUGE (스트레인 게이지를 이용한 수종 수복재의 중합수축 영향 평가)

  • Lee, In-Cheon;Kim, Jong-Soo;Yoo, Seung-Hoon
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.36 no.1
    • /
    • pp.20-29
    • /
    • 2009
  • This study was performed to evaluate the effect of the shrinkage stress induced by polymerization process of several light curing filling materials according to filling methods. High power light curing unit which has a plasma arc lamp was used and filling materials used were Filtek $Z-250^{(R)}$ composite resin, $Dyract^{(R)}$ AP compomer and $Tetric^{(R)}$ Flow flowable composite resin. Cavities were prepared on the permanent molars with width 3 mm, height 3 mm and depth 1.5 mm and the filling materials were filled with 1 step, 2 step layering technique and 3 step oblique filling methods. The results can be summarized as follows; 1. Strain values showed rapid increase from the start of light curing followed by gradual decrease afterwards with time. 2. Although the shrinkage stress value of $Z-250^{(R)}$ were shown to be relatively higher than $Dyract^{(R)}$ AP and $Tetric^{(R)}$ Flow, no statistically significant could be found between tested materials(p>0.05). 3. There were no statistically significant difference between 3 filling methods when using $Dyract^{(R)}$ AP and $Z-250^{(R)}$(p>0.05). 4. There were no statistically significant difference between shrinkage stress values obtained from samples prepared by different filling methods and materials(p>0.05).

  • PDF

Setup Verification in Stereotactic Radiotherapy Using Digitally Reconstructed Radiograph (DRR) (디지털화재구성사진(Digitally Reconstructed Radiograph)을 이용한 정위방사선수술 및 치료의 치료위치 확인)

  • Cho, Byung-Chul;Oh, Do-Hoon;Bae, Hoon-Sik
    • Radiation Oncology Journal
    • /
    • v.17 no.1
    • /
    • pp.84-88
    • /
    • 1999
  • Purpose :To develop a method for verifying a treatment setup in stereotactic radiotherapy by ma- tching portal images to DRRs. Materials and Methods : Four pairs of orthogonal portal images of one patient immobilized by a thermoplastic mask frame for fractionated stereotactic radiotherapy were compared with DRRs. Portal images are obtained in AP (anteriorfposterior) and lateral directions with a target localizer box containing fiducial markers attached to a stereotactic frame. DRRs superimposed over a planned iso-center and fiducial markers are printed out on transparent films. And then, they were overlaid over onhogonal penal images by matching anatomical structures. From three different kind of objects (isgcenter, fiducial markers, anatomical structure) on DRRs and portal images, the displacement error between anatomical structure and isocenters (overall setup error), the displacement error between anatomical structure and fiducial markers (irnrnobiliBation error), and the displacement error between fiducial markers and isocenters (localization error) were measured. Results : Localization error were 1.5$\pm$0.3 mm (AP), 0.9$\pm$0.3 mm (lateral), and immobilization errors were 1.9$\pm$0.5 mm (AP), 1.9$\pm$0.4 mm (lateral). In addition, overall setup errors were 1.0$\pm$0.9 mm (AP), 1.3$\pm$0.4 mm (lateral). From these orthogonal displacement errors, maximum 3D displacement errors($\sqrt{(\DeltaAP)^{2}+(\DeltaLat)^{2}$)) were found to be 1.7$\pm$0.4 mm for localization, 2.0$\pm$0.6 mm for immobilization, and 2.3$\pm$0.7 mm for overall treatment setup. Conclusion : By comparing orthogonal portal images with DRRs, we find out that it is possible to verify treatment setup directly in stereotactic radiotherapy.

  • PDF

A Study on the Performance of Home Embedded System Using a Wireless Mesh Network (무선 메쉬 네트워크를 이용한 홈 임베디드 시스템의 성능에 대한 연구)

  • Roh, Jae-Sung;Ye, Hwi-Jin
    • Journal of Digital Contents Society
    • /
    • v.8 no.3
    • /
    • pp.323-328
    • /
    • 2007
  • Communication systems beyond 3G should provide more than 100 Mbps for wireless access. In addition to smart antennas, wireless multi-hop networks are proposed to increase the cell size and throughput. For example, Zigbee technology is expected to provide low cost and low power connectivity and can be implemented in wireless mesh networks larger than is possible with Bluetooth. Also, home embedded system using wireless mesh network is one of the key market areas for Zigbee applications. If the line-of-sight path is shadowed by home obstacles, a direct connection between the access point (AP) and the node is not possible at high frequencies. Therefore, by using multi-hop relay scheme the end node can be reached to AP. In this paper, the relaying of data between the AP and the end node is investigated and the throughput and PER(Packet Error Rate) are evaluated in multi-hop wireless mesh networks by using DSSS/BPSK system.

  • PDF