• Proceedings of the KSPS conference
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• 1996.10a
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• pp.390-398
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• 1996

Acoustic analysis study was performed on 20 normal subjects by speaking nonsense syllables composed of Korean bilabial stops(/p, $p^{*}$/, ph/) and their Preceding and/or following vowel /a/(that is, [pa, $p^{*}a$, pha, apa, $ap^{*}a$, apha]) with an ultraminiature pressure sensor in their mouths. Speech materials were phonated twice, once with a moderate voice, another time with a loud voice. The acoustic signal and intraoral pressure were recorded simultaneously on computer. By these procedures, we were to measure the intraoral pressure, closure duration and VOT of Korean bilabial stops, and to compare the values one another according to the intensity of phonation and the position of the target consonants. Intraoral pressure was measured by the peak intraoral pressure value of its wave; closure duration by the time interval between the onset of intraoral pressure build-up and the burst meaning the release of closure; Voice onset time(VOT) by the time interval between the burst and the onset of glottal vibration. Heavily aspirated bilabial stop consonant /ph/ showed the highest intraoral pressure value, unaspirated /p$^{*}$/, the second, slightly aspirated /p/, the lowest. The syllable initial bilabial stops showed higher intraoral pressure than word initial stops, and the value of loudly phonated consonants were higher than moderate consonants. The longest closure duration period was that of /$p^{*}$/ and the shortest, /p/, and the duration was longer in word initial position and in the moderate voice. In VOT, the order of the longest to shortest was /ph/, /p/, /$p^{*}$/, and the value was shorter when the consonant was in intervocalic position and when it was phonated with a loud voice.

• Journal of Advanced Navigation Technology
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• v.19 no.1
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• pp.74-79
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• 2015

In this paper, in order to improve the error is utilized to location tracking the smart sensor detects a walking information user, RSSI is to provide an indoor position tracking system that is capable of correcting an error in terms weak. The acceleration sensor is able to detect the activity in the user walking and detects the number of step and the moving distance using the same. The Direction sensor is utilized as a digital compass, to detect the moving direction of the user. As a result of detecting the walking information using the sensor, it can be showed that this proposed indoor positioning system has a high degree of accuracy for the number of steps and the movement direction. Therefore, this paper shows that the proposed technique can correct the error of the location information to be problem in the conventional indoor location system which uses the only Wi-Fi APs by estimating the user's movement direction and distance using the sensors in smartphone without an additional equipment and cost.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2013.10a
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• pp.307-309
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• 2013

Diligence/Indolence records are the basic data at a human resource management and the essential data for measure salaries of employees. However, since the D/I systems using RFIDs or biometric sensors require hish costs to build and operate the D/I systems, it is difficult for to small business or self-employed business to use them. In this paper, we propose the Diligence/Indolence system to use the location identification of a smart phon. To locate the position of an employee, the WiFi signal of a smart phone and the wireless access point are exploited. Because the pre-owned hardware resources are used and initial building costs are low, it is easy for small business to use the proposed D/I system with low cost.

• Molecules and Cells
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• v.20 no.3
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• pp.429-434
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• 2005

Lysophosphatidylcholine (lysoPC) induces vascular smooth muscle cell (VSMC) proliferation and migration, which has been proposed to initiate the intimal thickening in coronary atherosclerotic lesions. Berberine is an alkaloid in Berberis aquifolium and many other plants. Recently, it has been shown to have beneficial effects on the cardiovascular system, such as anti-hyperglycemic and cholesterol-lowering activity. In this study, we investigated its effects on lysoPC-induced VSMC proliferation and migration. Berberine inhibited lysoPC-induced DNA synthesis and cell proliferation in VSMCs, as well as migration of the lysoPC-stimulated VSMCs. It also inhibited the activation of extracellular signal-regulated kinases (ERKs) and reduced transcription factor AP-1 activity and the lysoPC-induced increases in intracellular reactive oxygen species (ROS). These results indicate that the inhibitory effects of berberine on lysoPC-stimulated VSMC proliferation and migration are attributable to inhibition of ROS generation and hence of activation of the ERK1/2 pathway. This suggests that berberine has potential in the prevention of atherosclerosis and restenosis.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.34-34
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• 2003

Protein unfolding is a key step in several cellular processes, including protein translocation across some membranes and protein degradation by ATP-dependent proteases. C1pAP protease and the proteasome can actively unfold proteins in a process that hydrolyzes ATP, These proteases catalyze unfolding by processively unraveling their substrates from the attachment point of the degradation signal. As a consequence, the ability of a protein to be degraded depends on its structure as well as its stability. An ${\alpha}$-helix is easier to unravel than a ${\beta}$-strand. In multidomain proteins, independently stable domains are unfolded sequentially. The steric constraints imposed on substrate proteins during their degradation by the proteasome were investigated by constructing a model protein in which specific parts of the polypeptide chain were covalently connected through disulfide bridges. The cross-linked model proteins were fully degraded by the proteasome, but two or more cross-links retarded the degradation slightly. Our results suggest that the pore of the proteasome allows the concurrent passage of at least three stretches of a polypeptide chain, and also explain the limited degradation by the proteasome that occurs in the processing of the transcription factor NF-KB, and also implicate difficulty in degradation of amyloidal aggregates by the proteasome

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.1
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• pp.226-232
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• 2015

As the age of smart device has come, recently many application services related to smart phone are developing. The LBS(Location Based Service) technique is considered as one of the most important techniques to support location based application services. Usually the smart phone acquires the information of position by using the position recognition systems and sensors such as GPS(Global Positioning System) and G-Sensor. However, since the GPS signal from the satellite can hardly be received in the indoor environments, new LBS techniques for the indoor environment are required. In this paper, to solve the problem a position information transceiver using LED lights and smart phone camera sensor is proposed. We proved the possibility of the proposed positioning system through the experiments in the laboratory for the practical verification.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.499-503
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• 2005

The objective of this thesis is to measure the limit of the real space where wireless Local Area Network(LAN) is used, and to apply this result as reference to set up a real Wireless LAN environment. The organized circumference was composed of Wireless LAN based on IEEE 802.11b of the American standard, and the examination is carried out on the campus. On the real condition of office environment and open space, the ratio of available distance to a signal at each distance was measured and this result was studied as data to embody wireless LAN on the campus. The measurement under an indoor environment was executed under circumstance having two wall and open space, however, was executed respectively under three circumstances : Where no obstacle, where one wall exists, and where two or more walls exist.

• Journal of Microbiology and Biotechnology
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• v.16 no.10
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• pp.1605-1612
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• 2006

Interleukin (IL)-18, a member of the family of IL-l cytokine, is one of the principal inducers of $interferon-{\gamma}(IFN-{\gamma})$ in T lymphocytes and natural killer cells. The objective of the present study was to evaluate the effect of IL-18 on the expression of chemokine IP-10 (CXCL-10) mRNA in mouse peritoneal macrophages. IL-18 had very weak direct effect or synergistic effect with IL-12 on the expression of IP-10 mRNA in C57BL/6 mouse peritoneal macrophages. However, IL-18 pretreatment was found to playa cooperative role in the expression of lipopolysaccharide (LPS)-induced IP-10 mRNA. For the expression of LPS-induced IP-10 mRNA, the synergistic effect was detected after 16 h of IL-18 pretreatment prior to LPS stimulation. The expression level of CD14 in cells stimulated with LPS was not changed by IL-18 pretreatment, and the level of $IFN-{\gamma}$ production during IL-18 pretreatment plus LPS stimulation was barely discernible ($0.36{\pm}0.31pg/ml$). Namely, the synergistic effect of IL-18 pretreatment was not related to a change of LPS receptor, CD14 expression, and the production of $IFN-{\gamma}$ by the interaction between IL-18 and LPS. The synergistic effect of IL-18 pretreatment on the expression of LPS-induced IP-10 was related to not NF-kB but AP-1 activation, and associated with the extracellular signal-regulated kinase (ERK) pathway, one of the mitogen-activated protein kinase signaling pathways. These results provide useful information that may elucidate the mechanisms underlying the effect of IL-18 on the expression of IP-10 mRNA.

• Journal of Satellite, Information and Communications
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• v.9 no.2
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• pp.85-90
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• 2014

In this paper, we propose a novel UE(User Equipment) position tracking algorithm of visible light signals, and analyze BER performance when optical beamforming scheme is applied in VLC(Visible Light Communications) system. The optical beamforming scheme as an interference mitigation method provides good optical channel conditions between UE(Rx) and LED light(Tx), and lead to better BER performance because UE is able to get a better RSSI(Received Signal strength indication) value. For the system BER, the proposed UE position tracking method for optical beamforming transmission demonstrates the performance enhancement compared to a system not applied the optical beamforming transmission scheme, and up to about 5~6dB SNR performance gain is achieved. The results of the paper can be applied to design of various VLC and LBS applications for ubiquitous home network systems.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.18 no.2
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• pp.466-474
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• 2014

According to wireless network technology and mobile processors performance were improved, the small wireless mobile device such as smart phones has been widely utilized. The mobile devices can be used GPS information, thereby the services based on location information was increased. GPS was impossible to provide location information in indoor and signal shading environment, and the tracking systems based on short distance wireless communication are required infrastructure. The IEEE 802.11 based tracking system is possible estimation using APs, however the tracking device is exhausted battery power seriously. In this paper, we propose IEEE 802.11 based low-power tracking system. We reduced power consumption from channel scanning and network connection. For performance evaluation, we designed and implemented the tracking tag device, and measured power consumption of the device. As the simulation result, we confirmed that the power consumption was reduced 46% compare to the standard execution.