• Journal of Gastric Cancer
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• 제4권3호
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• pp.180-185
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• 2004

Recently, we experienced two advanced gastric cancer (AGC) patients younger than 17 years of age. The first case was a 15-year, 2-month-old male who had suffered from epigastric soreness for 5 weeks. His grandfather died of gastric cancer at 39 years of age. Under the diagnosis of AGC, he underwent a total gastrectomy with D2 lymph node dissection. There was no evidence of distant metastasis. Pathologic examination revealed a 4.5$\times$4 cm, signet ring cell adenocarcinoma with subserosal invasion and with metastasis in 9 of 42 regional lymph nodes (T2bN2M0). The second case was a 17-year, 11-month-old male who had suffered from epigastric pain for 2 years without familial clustering. Under the diagnosis of AGC, he underwent a distal subtotal gastrectomy with D2 lymph node dissection. There was no evidence of distant metastasis. Pathologic examination revealed a 3$\times$2 cm, signet ring cell adenocarcinoma with subserosal invasion and with metastasis in 9 of 45 regional lymph nodes (T2bN2M0). The two patients have been alive without recurrence for 27 months and 4 months, respectively. Even among teenagers, patients with abdominal complaints should be subjected to a thorough examination of the gastrointestinal tract.

• 한국수산과학회지
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• 제48권6호
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• pp.929-939
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• 2015

We studied the characteristics of age and growth of the Goldeyes rockfish Sebasetes thompsoni in the Ulleungdo and Dokdo areas by using 730 otoliths from February 2013 to February 2014. The lowest value of the marginal index was found in June once a year. The spawning period was estimated as April. Therefore, the duration from fertilization to the complete formation of the first annual growth ring is fourteen months. From the parameters calculated using the weighted average length of the year ring formation, the growth of S. thompsoni was demonstrated by the von Bertalanffy growth equation as $L_t=34.68(1-e^{-0.2113(t+0.7683)})$ for females and $L_t=29.79(1-e^{-0.2163(t+1.7964)})$ for males, $L_t=32.84(1-e^{-0.25(t+0.57)})$ for combined sex. Comparing with growth performance index(${\Phi}$) from these 4 offshore areas, parameter of S. thompsoni in Ulleungdo area was 2.4087, that of in Tong-yeong was 2.2835, that of in Aomori was 2.4077 and in Niigata was 2.3927. As a result, the value of Dokdo and Ulleungdo areas showed the highest.

• 수산해양기술연구
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• 제51권1호
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• pp.35-41
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• 2015

The age and growth of the Marbled sole, Pleuronectes yokohamae were investigated using left sagittal otoliths of 832 individuals collected in the mid-southern waters of Korea from January 2006 to April 2007. The seasonal changes in the ratio of an translucent zone to interval between annular rings revealed that the boundaries between translucent and opaque parts of the otolith were annual growth rings formed between May and June once a year. The spawning period was November to March and therefore the duration from fertilization to the complete formation of the annual growth ring became fifteen months. The parameters of von Bertalanffy growth equations estimated using the average standard length at each age are the $L_{\infty}$ of 48.04cm, K of 0.1406/year and $t_0$ of -0.5116 for female and 26.14cm, 0.3056/year and -0.8202 for male, respectively. Finally, it is suggested that the growth of female is faster than that of male from age-2.

• 한국수산과학회지
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• 제48권5호
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• pp.760-767
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• 2015

First annulus formation and age determination of otoliths were examined for chub mackerel Scomber japonicus collected in Korean waters over the one year from January to December in 2009. Translucent zone was regarded as an annual mark. Age interpretation criteria was based on the data of the number of translucent zone, capture date, and edge type of the otolith, assuming the nominal birthday to be 1 January. Monthly changes in mean marginal index indicated that translucent zone was formed once a year, mainly in June. The otolith of 0-ring group was detected comparing the progression by month of the smaller fish length, appearing to be a single first opaque zone. The average distance from the core to the first translucent zone was ~1.77 mm, provided as supplementary information to increase ageing accuracy. The ageing criteria for chub mackerel was made to determine correct year-class with the purpose of effective stock assessment. This method using nominal birthdate and edge type analysis could estimate age of fish closer to the true age than purely counting the number of translucent zone on a whole otolith.

• 헤리티지:역사와 과학
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• 제43권3호
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• pp.48-101
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• 2010

이 논문은 한반도 남부와 일본열도 서반부를 중심으로 한 지역에 있어서 금속기의 생산과 유통이 활발했던 시기의 실연대를 $^{14}C$연대측정을 통해 추정한 글이다. 이 시기의 일상용기였던 점토대토기의 실연대를 구축하여, 토기와 금속기의 고고학적 출토양상을 통해 세형동검문화의 성립과 철기의 출현연대를 밝히고자 하였다. 연구사를 통해 점토대토기 기원전 300년 상한설이 학계의 대세임을 알 수 있는데, 이는 현재에도 계속해서 지지되고 있다. 이것은 세형동검문화의 성립연대와 초기철기시대의 개시연대와도 연동되고 있는 것이다. 한편에서는 세형동검문화와 원형점토대토기문화의 성립을 동일시하는 견해를 지지하지 않는 연구자도 있으며, 목탄의 $^{14}C$연대를 통해 점토대토기의 출현시기를 올려 보는 분위기가 형성되고 있었다. 연구사에서 드러난 문제점을 지적하면서, 필자가 직접 조사를 통해 채취 처리한 시료를 중심으로 $^{14}C$연대측정을 실시, 그 결과를 바탕으로 점토대토기의 실연대를 구축하였는데, 그 시료는 약 100점에 달한다. 원형점토대토기는 기원전 6세기에 출현했을 가능성이 높고, 삼각형점토대토기는 기원전 300년 전후에 출현한 것으로 파악하였다. 철기는 원형점토대토기의 가장 늦은 단계에 출현하기 때문에 그 출현연대를 기원전 4세기라고 볼 수 있는데, 이는 실제로 철기와 원형점토대토기가 공반된 유적의 $^{14}C$연대와도 정합적이었다. 이를 통해 기원전 4세기 초~중엽일 가능성을 제시하였고, 초기 철기가 출토된 유적보다 확실히 이전 단계에 해당되는 초창기의 세형동검문화는 기원전 5세기 후반으로 파악하였다. 이렇게 파악된 실연대는 야요이토기와의 병행관계 및 $^{14}C$연대와도 정합적이며, 고고학적 사실에 근거한 것이기 때문에 가능성 높은 연대라고 할 수 있다. $^{14}C$연대를 통한 한일 공통의 편년이 처음으로 구축된 것이다. 새로이 구축된 점토대토기의 실연대에 의하면, 현재 학계의 일반적인 시대구분과는 맞지 않기 때문에, 연대의 조정을 통해 새로운 수정안을 제시하였다. 철기의 출현시기(기원전 4세기 초~중엽)부터 초기 철기시대로 하여, 청동기시대는 원형점토대토기 단계의 상당 부분과 세형동검문화를 포함하는 것으로 보았다. 이를 청동기시대 후기로 설정하여, 송국리식을 중기로 하는 안을 제시하였다.

• 한국제4기학회지
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• 제17권2호
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• pp.55-61
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• 2003

In the year 2000 we culminated a successful five year investigation of climate change by completing a preliminary east-west transect across Mongolia. An earlier tree-ring study at Tarvagatay Pass, Mongolia indicated unusual warming during the 20th century similar to other paleo-investigations of the northern hemisphere. This record had represented one of the few tree-ring records for central Asia. New data from several sites in western Mongolia confirmed the preliminary temperature. The highest twenty-year growth period for the composite record is from 1973-1994. The western Mongolian record was significantly correlated with the Taimyr Peninsula and two northern hemisphere temperature reconstructions reflecting large-scale temperature patterns while showing some important regional differences. These differences should prove useful for climate models. We have also developed a millennial length temperature-sensitive record at the Solongotyin Davaa site (formerly Tarvagatay Pass) using relict wood and living trees. Conspicuous features over the last 1000 years are a century scale temperature decline punctuated by the end of the Little Ice Age in the late-1800s and 20th century warming. The record also shows a cold period early in the 12th century and warm intervals late in the 10th, early in the 15th and at end of the 18th centuries. Despite a limited sample size before 900 AD, the long Solongotyin Davaa record is useful in indicating severe cold events and suggests some cold intervals nearly as severe. These tree ring series, spanning much of the circumpolar northern treeline, have been compiled to create a long-term reconstruction of the Earth's temperature over centuries. The new chronology, in addition to its value as a detailed record of Mongolian climate, provides independent corroboration for such hemispheric and global reconstructions and their indications of unusual warming during the 20th century.

• BMB Reports
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• 제44권11호
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• pp.725-729
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• 2011

We report a novel mechanism of a CDH1 splicing mutation in a patient with signet ring cell carcinoma of the stomach. A 27-year-old man complaining of aggravated dyspepsia was diagnosed with signet ring cell carcinoma. Both his father and uncle had died of stomach cancer at a young age. DNA sequencing analysis of the CDH1 gene revealed a splice site mutation (c.833-2A>G). By RNA/cDNA sequencing analysis, CDH1 c.833-2A>G generated a new acceptor site within intron 6, causing the insertion of a 79-bp intronic sequence between exon 6 and 7 (r.833-79_833-1ins), and resulting in a frame shift. E-cadherin immunohistochemical staining revealed a loss of CDH1 expression. This study reveals the disease-causing mechanism of this splicing mutation, and emphasizes the need for functional studies using RNA samples for the accurate interpretation of detected splicing variant. This is the first reported case of a CDH1 mutation in a Korean patient.

• 한국농림기상학회지
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• 제7권4호
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• pp.289-295
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• 2005

본 논문은 경북지역 소나무의 연륜생장에 대하여 연륜생태학적 해석을 통하여 월별 기후인자(월별평균온도, 월별강수량)간의 관계를 기초통계량 및 상관분석을 실시하였다. 실측된 연륜생장곡선은 수령 및 비기후적인 요소를 제거하기 위하여 음지수생장곡선을 이용하여 표준화를 실시하였다. 경북지역 소나무 연륜생장과 기후인자간의 관계에서 당해연도 $2\~4$월까지의 월별평균온도가 정의 상관으로 영향을 미치고 있으며. 월별 강수의 경우 당해연도 $1\~3$월의 강수가 연륜생장에 정의 상관으로 영향을 미치는 것으로 나타났다. 이러한 결과로 미루어 경북지역 소나무의 연륜생장에 있어서 휴면기가 끝나고 생장이 시작되는 시점에서의 기후인자가 생장을 촉진시키는 요인인 것으로 판단된다.

• 한국수학사학회지
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• 제32권4호
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• pp.159-173
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• 2019

In this paper, we examine the brief history of the ring of four almonds regarding Mesopotamian mathematics, and present reasons why the Omar Khayyam's triangle, a special right triangle in a ring of four almonds, was essential for artisans due to its unique pattern. We presume that the ring of four almonds originated from a point symmetry figure given two concentric squares used in the proto-Sumerian Jemdet Nasr period (approximately 3000 B.C.) and a square halfway between two given concentric squares used during the time of the Old Akkadian period (2340-2200 B.C.) and the Old Babylonian age (2000-1600 B.C.). Artisans tried to create a new intricate pattern as almonds and 6-pointed stars by subdividing right triangles in the pattern of the popular altered Old Akkadian square band at the time. Therefore, artisans needed the Omar Khayyam's triangle, whose hypotenuse equals the sum of the short side and the perpendicular to the hypotenuse. We presume that artisans asked mathematicians how to construct the Omar Khayyam's triangle at a meeting between artisans and mathematicians in Isfahan. The construction of Omar Khayyam's triangle requires solving an irreducible cubic polynomial. Omar Khayyam was the first to classify equations of integer polynomials of degree up to three and then proceeded to solve all types of cubic equations by means of intersections of conic sections. Omar Khayyam's triangle gave practical meaning to the type of cubic equation $x^3+bx=cx^2+a$. The work of Omar Khayyam was completed by Descartes in the 17th century.

• Journal of the Korean Wood Science and Technology
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• 제47권1호
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• pp.90-100
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• 2019

본 연구는 수목의 수령을 조사하는 방법으로 레지스토그래피를 활용하는데 있어서 수종별로 가장 적합한 삽입속도를 찾기 위하여 수행되었다. 회전속도는 1,500 r/min로 고정하였다. 수종은 낙엽송, 더글라스 퍼, 잣나무, 전나무, 느티나무이다. 실험결과 수종에 따른 적합한 삽입속도는 느티나무 75 cm/min, 낙엽송과 더글라스 퍼 100 cm/min, 전나무 150 cm/min, 잣나무 175 cm/min으로 나타났다. 하지만 모든 경우에서 연륜폭이 1 mm이하일 경우 연륜경계 확인이 어려운 것으로 확인되었다. 연륜폭이 1 mm이하인 경우를 제외하고는 연륜폭측정기와 레지스토그래피의 연륜폭그래프는 매우 일치하였다. 향후 연륜폭이 1mm 이하인 미세연륜 확인이 가능한 레지스토그래피가 개발된다면 레지스토그래피가 수령조사를 위해 전통적으로 활용되는 생장편의 연륜관찰방법을 대체할 수 있을 것이다. 또한 레지스토그래피의 연륜폭그래프는 생장량 조사에도 활용할 수 있을 것으로 판단된다.