• Journal of Nutrition and Health
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• v.52 no.2
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• pp.168-175
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• 2019

Purpose: Barely sprout is a well-known oriental herbal medicine with a wide range of health benefits. Recent studies have provided scientific evidence of its therapeutic effects with expanded application. This study investigated anti-melanogenic effect of barley sprout water extract (BSE) in murine melanocyte B16F10. Methods: Various concentrations (0, 50, 125, and $250{\mu}g/mL$) of BSE and arbutin (150 ppm) were applied to B16F10 stimulated with or without alpha-melanocyte stimulating hormone (100 nM) for 72 hours. The whitening potency of BSE was determined altered cellular melanin contents. Activity and expression of tyrosinase and microphthalmia-associated transcription factor (MITF) were also assayed. Results: Experimental results revealed that treatment with BSE reduced cellular melanin production by approximately 40% compared to the control. Molecular findings supported that suppressed activity and expression of tyrosinase and MITF proteins by BSE were associated with declined cellular melanogenesis. Furthermore, anti-melanogenic effect of BSE ($250{\mu}g/mL$) was similar to that of arbutin, a commonly used whitening agent. Lastly, polyphenols including p-coumaric, ferulic, and vanillic acids were identified in BSE using HPLC analyses. They might be potential active ingredients showing such melanogenesis-reducing effect. Conclusion: BSE was evident to possess favorable anti-melanogenic potency in an in vitro model. As a natural food sourced material, BSE could be an effective depigmentation agent with potential application in pharmaceutical and cosmetic industries.

• Journal of the Korean Recycled Construction Resources Institute
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• v.7 no.1
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• pp.44-49
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• 2019

The purpose of this study is to analyze the fundamental characteristics of concrete with the change of reject ash(Reject ash=Rj) in the mixed aggregate where single grain aggregate of different grain size and aggregate of opposite grain size are mixed together, to analyze the possibility of a mixed aggregate system that premixes at an aggregate manufacturing plant and delivers it as one aggregate. As a result of the experimental study, it was found that the grain size regulation is satisfied if the mixed aggregate(CSb+SS) is substituted for about 5% of Rj. In the case of the fluidity slump, slump flow and air volume, it was found that they decrease as the substitution ratio of Rj increases, while the compressive strength increases as the substitution ratio of Rj increases. Therefore, it is analyzed that it would contribute greatly to an improvement of quality such as improvement of compressive strength if adequate fluidity and air quantity are secured by the water reducing agent and AE agent while premixing the Rj, which is disposed of by landfill, with about 5% of the mixed aggregate.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.369-372
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• 2008

This study analysis fundamental properties of high-strength concrete corresponding to W/B ratio for suggested table of high strength concrete, mixed with premixed cement. As a result of this study, the amount of using air entraining and high-range water reducing agent for intended slump flow and air content decreased as W/B increased, and the setting time corresponding to the W/B ratio delayed as W/B ratio increased except 20% W/B ratio. The compressive strength according to W/B ratio decreased as W/B ratio increased, and there was no great deferent as the intended slump flow. Also it could possible to use this study at work as the correlation coefficient is high enough as 0.9646 substituting B/W and compressive strength for the regression formula.

• Analytical Science and Technology
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• v.14 no.1
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• pp.34-43
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• 2001

The present work is aimed to evaluate the conditions of the hydride generation (HG) for germanium analysis by inductively coupled plasma (ICP)-atomic emission spectrometry (AES). Twelve different kinds of acids were used such as phosphoric, hydrochloric, nitric, sulfuric, perchloric, boric, tartaric, malic, oxalic, tannic, citric, and acetic acid. It was found that phosphoric acid yielded the maximum efficiency of hydride generation. Also, efficient hydride generation was obtined with the buffer solutions containing phosphate ions over a wide range of pH. In addition, in the presence of phosphoric acid the interference caused by metals was suppressed in the hydride generation of germanium. As the concentrations of a reducing agent and a stabilizing increased the hydride generation efficiency and the acid concentration proviaing the maximum intensity were increased. By using an analytical method developed in this study, the contents of germanium in water and rock samples were determined. The detection limit of germanium in the presence of phosphoric acid was $0.03{\mu}g/L$.

• Nutrition Research and Practice
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• v.8 no.3
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• pp.292-296
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• 2014

BACKGROUND/OBJECTIVES: This study was conducted to assess the potential of St. John's Wort (Hypericum perforatum) to prevent obesity and abnormalities in lipid metabolism induced by ovariectomy in a rat model without stimulatory activity on uterus. MATERIALS/METHODS: Ovariectomized (OVX) rats were treated for 6 weeks with 70% ethanol extracts of Hypericum perforatum [HPEs: whole plant (WHPE) and flower and leaves (FLHPE)], ${\beta}$-estradiol-3-benzoate at a dose of $50{\mu}g/kg/day$ (E2) or vehicle (distilled water). RESULTS: As expected, OVX increased body weight gain and adiposity and showed higher food efficacy ratio. OVX also increased the serum cholesterol as well as insulin resistance, while reducing uterus weight and uterine epithelial proliferation rate. HPEs (WHPE and FLHPE) showed estrogen-like effect on body weight gain, adipose tissue weight and food efficacy ratio in OVX rats. HPEs prevented hypercholesterolemia induced by OVX more effectively than E2. E2 increased uterus weight and epithelial proliferation rate in OVX rats, while HPEs maintained them at the level of the sham-operated animals. CONCLUSIONS: Our finding demonstrates that HPEs can be considered as an effective agent to prevent OVX-induced obesity without stimulatory activity on uterus.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.733-736
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• 2008

This study, with the purpose for early quality improvement of concrete which used large quantity of fly ash, changed various admixture material type and reviewed the basic characteristics. First off, the flow overall was highest when polycarb onic Acid high early strength AE water reducing agent was displaced, while air amount satisfied target level only in the case of plain, and setting time was shown best by getting 30 more minutes than plain and about 3 more hours than conventional when KOH is displaced. Compressive strength was shown best at age 1 day and 3 days when KOH was displaced, and at age 28 days when fine particle cement was displaced. By and large, this study concludes that concrete quality improvement admixture material that used large amount of fly ash showed worse effects than plain, therefore it is determined that there need be more study for development of concrete early quality improvement admixture material that used large amount of fly ash.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.737-740
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• 2008

This study, with the purpose for early quality improvement of concrete which used large quantity of fly ash, changed various admixture material type and reviewed the basic characteristics. First off, the flow overall was highest when polycarb onic Acid high early strength AE water reducing agent was displaced, while air amount satisfied target level only in the case of plain, and setting time was shown best by getting 30 more minutes than plain and about 3 more hours than conventional when KOH is displaced. Compressive strength was shown best at age 1 day and 3 days when KOH was displaced, and at age 28 days when fine particle cement was displaced. By and large, this study concludes that concrete quality improvement admixture material that used large amount of fly ash showed worse effects than plain, therefore it is determined that there need be more study for development of concrete early quality improvement admixture material that used large amount of fly ash.

• Journal of the Korea Institute of Building Construction
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• v.22 no.1
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• pp.23-34
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• 2022

The purpose of this study is to evaluate the adhesion properties of polymer cement composites for crack repair of an RC structure. Polymer cement composites are manufactured from cement, three types of polymers and silica fume, and the mixture is designed by adjusting the water cement ratio and AE reducing agent so that the viscosity target of the polymer cement composites is 700mPa·s or less. According to the test results, the Type-A adhesion in tension of the polymer cement composite exceeded the adhesion standard of 1.0MPa of the polymer finishing material, and furthermore, depending on the type of polymer, the adhesion in tension was highest for SAE, followed in descending order by EVA, and SBR. In addition, the adhesion in tension of Type-B is up to 1/4.5 lower than that of Type-A, but the incorporation of silica fume shows a significant improvement in terms of adhesion in tension. Based on this study, the basic mixing design of the polymer cement composites required for viscosity and adhesive performance required for crack repair of the RC structure was completed. It could be proposed as an optimal mixing design under conditions for intermixing polymer type EVA, SAE, and P/C 80%-100%.