• 대한간호학회지
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• 제30권5호
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• pp.1368-1378
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• 2000

This study was conducted to explore the nurse's perception of technological development and professional self-concept. The research subjects were 560 clinical nurses in Korea, who worked the general hospitals in Seoul, Kyeonggi, and the Kangwon province. Data sampling was done for the month, of December. 1997. The research tool consisted of 82 items questionnaires which were demographic data, TIQ, PSCNI. The research findings were as follows: 1. Nurses perceived the technological development as slightly positive (Mean =48.8). Also, nurses saw that the fastest developing technological nursing unit was the cardiac care unit, while the lowest technological developing nursing unit was the psychiatric unit. 2. The view of technological development was found to be significantly different according to religion (P=.0109), marital status (P=.0431), and the practical setting (P=.0048). Professional self concept was significantly different according to age (P=.0001), religion (P=.0001), education (P=.0007), marital status (P=.0000), career (P=.0001), and position (P=.0000). 3. The relationship between a nurse's perception of technological development and professional self-concept was highly correlated(r=.26, P=.0001). In the results of the multiple regression, the factors influencing professional self-concept were career, the nurse's perception of technological development, the level of technological development in nursing unit, and education. All these parameters showed the explaining power of 15.4% of the professional self-concept. In conclusion, nurses recognized the technological development was related to the professional self-concept. This study shed light on the meaning of technological development and vision of the nursing profession. Inservice education program should be developed to help the adaptability to technological development and conduct the qualitative research to explore the world of technological development which the nurses are experiencing in nursing.

• 치위생과학회지
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• 제18권5호
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• pp.319-326
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• 2018

Although scaling is the primary method for improving oral health, it is also associated with dental fear. The objective of this study was to empirically verify whether the use of gel anesthetic within the gingival sulcus during scaling relieves pain and improves other factors. A total of 128 patients scheduled to undergo scaling at a dental clinic of a general hospital located in the Gyeonggi Province, between July 2014 and July 2015, were enrolled in the study. The participants underwent scaling following the application of 20% benzocaine gel or placebo gel anesthetic within the gingival sulcus, and the data was collected using a questionnaire. There was a significant difference in the severity of pain, participant satisfaction, perceived sensitivity, overall discomfort, and fear of scaling between the two groups. The two groups were compared in terms of perceived need for gel anesthesia, willingness to pay for anesthesia costs, and willingness to receive scaling in the future. There were significant differences in all the three parameters depending on whether gel anesthesia was used or not. There were significant differences between the two groups in perceived sensitivity immediately after scaling and one day after scaling, with no difference seen one week after scaling. With regards to overall discomfort over time, there were significant differences between the two groups immediately after scaling. Based on these findings, we expect that application of gel anesthetic within the gingival sulcus during scaling will reduce pain, perceived sensitivity, overall discomfort, and fear of scaling with increased satisfaction.

• 대한화학회지
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• 제43권1호
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• pp.85-91
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• 1999

Phenyl N,N-diethyl-P-benzylphonamidate 및 그 유도체들의 염기성 가수분해 반응속도 상수를 분광 광도법으로 측정하였다. 속도 상수로부터 열역학적 파라메타(Ea, ${\Delta}H^{\neq}$,${\Delta}S^{\neq}$)를 구하였고, 이탈기의 치환기 효과는 Hammett 식을 이용하여 얻었다. 이들 실험 자료에 의하면 가수분해 반응은 활성화 엔트로피가 양의 값이나 작은 음의 값을 갖고 카르보음이온 생성이 수반되는 해리반응 보다는 이중피라미드 중간체 또는 전이 상태를 경유하는 회합 메카니즘을 강력히 암시하고 있다. 반응속도론적 연구 결과에 의하면 치환 pheny N,N-diethyl-P-benzylphosphonamidates의 가수분해 반응은 회합성 메카니즘으로 진행됨을 알 수 있었다.

• 한국수자원학회논문집
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• 제36권6호
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• pp.901-910
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• 2003

논의 수문학적인 거동은 물관리에 따른 담수심 상태, 벼의 생육시기별 물꼬관리에 크게 지배 받는다. 강우사상에 의한 논에서의 저류 및 배수량은 하천유량에 적지 않은 영향을 준다. 본 연구에서는 홍수기 논의 저류효과를 정량적으로 파악하기 위하여 논의 저류량을 모의할 수 있는 일별 물수지 모형을 개발하고, 수원과 여주의 논을 대상으로 4년간(1996, 1997, 2001, 2002) 측정한 자료를 이용하여 모형의 적용성을 검토하였다. 모형에서 물꼬높이와 기준 담수심(관개를 해야하는 한계 달수심)을 10일 단위의 매개변수로 처리하여 일별 담수심을 재현할 수 있었다. 홍수기 논의 저류량은 425.1 mm - 850.8 mm의 강우량 변동폭에 대하여 305.9 mm - 343.6 mm의 상대적으로 작은 저류량 변동폭을 보였다.

• 한국수산과학회지
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• 제36권4호
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• pp.358-364
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• 2003

Gross energy intake fecal, nitrogen excretory and metabolized energy of snotted halibut juvenile, Eopsetta grigorjewi, fed on Tigriopus iaponicus (Group A) and the enriched Artemia nauplii (Group B), were quantitatively investigated and represented as balance equations of energy and material. Absorption efficiency (AE), gross conversion efficiency $(K_1)$ and net conversion efnciency $(K_2)$ were also estimated to understand the changes in efficiency by the prey Gross energy intake, fecal, nitrogen excretory, metabolized and growth energy of Group A were $2.790\pm0.247,\;0.495\pm0.046,\;0.018\pm0.003,\;0.214\pm0.047\;cal\;mg^{-1}\;day^{-1}$ and $2.063\;cal\;mg^{-1}\;day^{-1},$ respectively. The same parameters of Group B were $4.801\pm0.165,\;0.579\pm0.031,\;0.055\pm0.010,\;0.306\pm0.048\;cal\;mg^{-1}\;day^{-1}$ and $3.861\;cal\;mg^{-1}\;day^{-1},$ respectively. Energy budget of Group A and B were represented as 100 C= 7.67 M+17.7 F+0.65 U+73.94 G and 100C=6.37 M+ 12.1 F+1.15 U+80.42 G, respectively, where C, M, F, U, and G represent gross energy intake, metabolized energy, fecal energy, nitrogen excretory (non-fecal) energy and growth energy, respectively. AEs of Croup A and B were $81.52\pm1.89,\;86.79\pm0.70\%,$ respectively, with significant difference at p=0.01 level. However, $K_1\;and K_2$ of Group A and B showed no significant difference at p=0.01 level, with $74.21\pm6.57,\;80.48\pm2.76\%\;and\;91.17\pm7.26,\;92.74\pm2.69\%$ respectively. These results suggest that T. japonicus is a possible substitute for Artemia nauplii for the snotted halibut juvenile.

• Nutritional Sciences
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• 제8권4호
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• pp.262-267
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• 2005

Reactive oxygen species can be generated in the skin by hair dyeing. The aim of this study was to find out the effects of the oxidative-type hair dye application in young women on the antioxidant systems. We investigated the lipid peroxide levels, glutathione (GSH) levels, and the antioxidant enzyme activities including superoxide dismutase (SOD), glutathione peroxidase (GSHPx) in plasma and erythrocytes and catalase (CAT) in erythrocytes, and DNA damages in lymphocytes. Also, plasma concentrations of antioxidant vitamins, vitamin A and E, were measured and the correlations between various antioxidant parameters and oxidative damages were evaluated The antioxidant enzyme activities in plasma (GSHPx) and in erythrocytes (SOD and CAT) were decreased significantly after hair dyeing. 1be lipid peroxide and GSH levels were not affected in both plasma and erythrocytes. No significant difference was found in the concentrations of both vitamin A and E between before and after hair dyeing. However, DNA damages expressed as the tail extent moment (TEM) and tail length (TL) were significantly (p<0.001) increased. The plasma vitamin E concentration was correlated with DNA damages (TEM: r=-0.590, p<0.01 and TL: r=-0.533. p<0.01) and RBC SOD activity (r=0.570, p<0.05). In turn, RBC SOD activity was significantly correlated with both plasma MDA levels (r=-0.412, p<0.05) and DNA damages (TM: r=-0.546, p<0.01, TL: r=-0.493, p<0.01). Our results demonstrated that the exposure to hair dyeing produced lymphocyte DNA damage and modification of the antioxidant enzyme activities. Also, there were very strong associations between plasma vitamin E concentration, RBC SOD activity and DNA damage induced by hair dyeing. It suggests that the antioxidant status of a subject is likely to be related to the extent of the harmful effects caused by hair dyeing.

• Nutrition Research and Practice
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• 제8권5호
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• pp.571-579
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• 2014

BACKGROUND/OBJECTIVES: The objectives were to investigate the effect of a 12-wk intervention with behavioral modification on clinical characteristics and dietary intakes of young and otherwise healthy obese and to identify factors for successful weight loss. The goal was to lose 0.5 kg per week by reducing 300-500 kcal/day and by increasing physical activities. SUBJECTS AND METHODS: Forty four obese subjects (BMI > 25) and 19 normal weight subjects (BMI 18.5-23) finished the 12-week intervention. Obese subjects participated in 5 group educations and 6 individual counseling sessions. Normal weight subjects attended 6 individual counseling sessions for evaluations of dietary intake and exercise pattern. Anthropometric and clinical characteristics and 3-day dietary records were evaluated at baseline and week12. RESULTS: Weight and serum triglyceride and free fatty acid concentrations in obese group decreased significantly with intervention. Intakes of energy, fat, and cholesterol decreased significantly in the obese. Active participation, realistic weight loss goal setting, and weight gain after high school graduation not during childhood were identified as key factors for successful weight loss. CONCLUSIONS: The 12-week intervention with behavioral modification resulted in reduced energy and fat intakes and led to significant weight loss and improvements of clinical characteristics in the obese. The finding that those who became obese during childhood lost less weight indicates the importance of 'early' intervention.

• 동력기계공학회지
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• 제19권5호
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• pp.60-66
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• 2015

Embrittlement of material by hydrogen charging should be cleared for safety of storage vessel of hydrogen and components deal with hydrogen. A stainless steel is generally used as materials for hydrogen transportation and storage, and it has a big advantage of corrosion resistance due to nickel component in material. In this study, microscopic damage behavior of stainless steel according to the hydrogen charging time using nondestructive evaluation was studied. The surface of stainless steel became more brittle as the hydrogen charging time increased. The parameters of nondestructive evaluation were also changed with the embrittlement of stainless steel surface by hydrogen charging. Ultrasonic test, which is the most generalized nondestructive technique, was applied to evaluate the relationship between the ultrasonic wave and mechanical properties of stainless steel by hydrogen charging. The attenuation coefficient of ultrasonic wave was increased with hydrogen charging time because of surface embrittlement of stainless steel. In addition, acoustic emission test was also used to study the dynamic behavior of stainless steel experienced hydrogen charging. AE event at the hydrogen charged specimen was obviously decreased at the plastic zone of stress-strain curves, while the number of event for the specimen of hydrogen free was dramatically generated when compared with the specimens underwent hydrogen charging.

• 환경위생공학
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• 제19권3호
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• pp.1-12
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• 2004

This study was conducted to evaluate the variation characteristics of influent and effluent quality from sewage treatment facilities using activated sludge processes and to assess the impact caused by discharge of treated sewage on the receiving water Monthly data of five water quality items (BOD, COD, SS, T-N, T-P) were used to understand the water quality at three sewage treatment plants in Seoul for five years from 1999 to 2003. Concentration differences of water quality parameters were observed between upstream and downstream site at the sewage treatment plant outfall to investigate the impact of discharge in Tan stream and Han river basin. 1. Due to the effect of continuous improvement in sewer system, the concentrations of influent went on increasing generally. 2. Effluent concentrations of BOD, COD and SS showed the trend of a little decreasing, but the trend of increasing in T-N and T-P. 3. In Tan stream basin, the impact of sewage treatment plant discharge was not observed directly, because concentration of discharge was lower than stream water's. But discharges from sewage treatment plants affected water quality at downstream site in Han river, concentration of T-P especially.

• Biomolecules & Therapeutics
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• 제15권2호
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• pp.102-107
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• 2007

Cimetidine, a substrate for P-glycoprotein (P-gp), is a well known drug interacting with a variety of drugs and results in alteration of pharmacokinetic parameters by concomitant administration. The aim of present study was to investigate whether cimetidine affects the transport of various quinolone antibiotics in human colorectal cancer cell line (Caco-2) system which has been typically used to investigate drug transport via P-gp. The apparent permeability coefficients (P$_{app}$) value of 9 quinolone antibiotics in the co-treatment with cimetidine was examined. Apical to basolateral (AP-to-BL) transport of fleroxacin in the co-treatment with cimetidine was increased to 1.5-fold (p<0.01) compared with that of fleroxacin alone, whereas basolateral to apical (BL-to-AP) transport of fleroxacin was decreased to 0.83-fold significantly (p<0.05). Ofloxacin was decreased to 0.8-fold (p<0.01) and 0.72-fold (p<0.01) significantly in AP-to-BL and BL-to-AP direction, respectively by cimetidine cotreatment. The P$_{app}$ values of gatifloxacin, moxifloxacin, ciprofloxacin and rufloxacin also were changed by cimetidine. These results have a potential that cimetidine influences on the pharmacokinetics of quinolone antibiotics. It suggests that careful drug monitoring and dosage adjustment may be necessary during the co-administration of quinolone antibiotics with cimetidine.