• Pediatric Infection and Vaccine
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• v.12 no.1
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• pp.75-85
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• 2005

Purpose : Fungal infection is one of the important causes of morbidity and mortality in patients with hematologic malignancies. Amphotericin B(ABV) and itraconazole(ITZA) have been used as the standard empirical antifungal therapy in neutropenic patients with acute leukemia who have persistent fever that does not respond to antibiotic therapy. ABV is an antifungal drug associated with side effects such as fever and chills, symptoms which may be mediated by pro-inflammatory cytokines such as interleukin-$1{\beta}$(IL-$1{\beta}$) and tumor necrosis factor-${\alpha}$(TNF-${\alpha}$). We assessed modulation of these pro-inflammatory cytokines as well as the anti-inflammatory cytokines(IL-4, IL-1Ra) by ABV and ITZA. Methods : From March 2004 to February 2005, a total of 30 episodes from acute leukemia patients with febrile neutropenia were analyzed for this study. They were randomly allocated to receive intravenous ABV or ITZA for 14 days. Clinical responses were evaluated at the completion of therapy, and cytokine IL-$1{\beta}$, TNF-${\alpha}$, IL-4, and IL-1Ra were measured for determination to know the correlation between two antifungal agents and inflammatory cytokines. Results : Empirical antifungal agents were given to 37 patients(ABV 20, ITZA 17), and 30 patients(ABV 15, ITZA 15) were evaluable for efficacy. White blood cell and absolute neutrophil count in the group treated with ITZA increased early days of treatment, so the duration of neutropenia in ITZA group is shorter. Serum creatinine level is lower in ITZA group than in ABV group but this is not statistically significant. There was no significant difference in response rate between two groups. The IL-$1{\beta}$ was increased in ABV treatment group and the ratio of IL-1Ra/IL-$1{\beta}$ is markedly decreased in ABV treatment group while increased in ITZA group. Conclusion : ITZA and ABV have at least equivalent efficacy as empirical antifungal therapy in neutropenic children with acute leukemia. However ITZA is associated with significantly less toxicity in clinical and molecular aspects.

• Membrane and Water Treatment
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• v.2 no.3
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• pp.175-185
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• 2011

Ultrafiltration is an emerging technology for drinking water treatment because it produces better water quality as compared with conventional treatment systems. More recently, the combination of UF technology with other processes in order to improve its performance has been observed. These associations aim to maximize the contaminants removal and reduce membrane fouling. The operational performance of contaminants removal and water production of two UF pilot plants was compared. The first plant (Guarapiranga) was fed with raw water and the second plant (ABV) with pre-treated water by the coagulation, flocculation and sedimentation processes at Alto da Boa Vista WTP (Sao Paulo, Brazil). Both units operated continuously for approximately 2,500 hours, from September/2009 to January/2010. The results showed that the ABV UF pilot plant was able to operate at higher specific fluxes (6.2 $L.d^{-1}.m^{-2}.kPa^{-1}$ @ $25^{\circ}C$) than Guarapiranga (3.1 $L.d^{-1}.m^{-2}.kPa^{-1}$ @ $25^{\circ}C$). However, the number of chemical cleanings conducted in both pilot units during the considered operation period was the same (4 chemical cleanings for each plant), which shows that the pre-treatment reduced the membrane fouling. The water quality at ABV for all the variables analyzed was better, but the feed water quality was also better due to pretreatment. The rejection values for the different contaminants were higher at Guarapiranga mainly because of a pollution load reduction after pre-treatment at ABV. Even with the better performance of the ABV UF pilot plant, it is necessary to take into consideration the complexity of the complete treatment system, and also the costs involved in the construction and operation of a full-scale treatment unit.

• Journal of applied mathematics & informatics
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• v.41 no.1
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• pp.107-121
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• 2023

An epidemic infectious disease model consists of six compartments viz. Susceptible, Exposed, Infected, Quarantine, Recovered, and Virus with nonlinear saturation incidence rate is proposed to know the viral disease dynamics. There exist two biological equilibrium points for the model system. The system's local and global stability is done through Lyapunov's direct method about equilibrium points. The sensitivity analysis has been performed for the basic reproduction number and equilibrium points through the normalized forward sensitivity index. Sensitivity analysis shows that virus growth and quarantine rates are more sensitive parameters. In support of mathematical conclusions, numerical experimentation has been shown.

• Journal of fish pathology
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• v.24 no.3
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• pp.237-245
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• 2011

Disease survey was conducted to investigate the cause of high mortality in 23 farms of eel, Anguilla japonica, during the period from 2000 to 2010. Seven kinds of fish pathogens were confirmed in the tested fish, which included: Pseudodactylogyrus sp. (infection rate: 65.5%, 19/29 samples), aquabirnavirus (ABV, 62.5%, 15/24 samples), Edwardsiella sp. (44%, 11/25 samples), anguillid herpesvirus 1 (AngHV1, 16.7%, 2/12 samples), Heterosporis sp. (10.3%, 3/29 samples), Vibrio sp. (8%, 2/25 samples), Trichodina sp. (3.4%, 1/29 samples). The rate of single infection was 44.8% (13/29 samples), while 62.1% (18/29 samples) showed mixed type of infection with 2 to 5 different pathogens. The most predominant mixed infection were Pseudodactylogyrus sp.-Edwardsiella sp. (10.3%, 3/29 samples), Pseudodactylogyrus sp.-ABV (10.3%, 3/29 samples), Edwardsiella sp.-ABV (6.9%, 2/29 samples). Infection by the above infectious parasites, bacteria and virus was confirmed in tested eels of juvenile to adult sizes that were cultured at $25{\sim}30^{\circ}C$ in almost the examined farms.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.5A
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• pp.517-525
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• 2006

In this paper, we present a high-speed RFID data filtering engine designed to carry out filtering under the conditions of massive data and massive filters. We discovered that the high-speed RFID data filtering technique is very similar to the high-speed packet classification technique which is used in high-speed routers and firewall systems. Actually, our filtering engine is designed based on existing packet classification algorithms, Bit Parallelism and Aggregated Bit Vector(ABV). In addition, we also discovered that there are strong temporal relations and redundancy in the RFID data filtering operations. We incorporated two kinds of caches, tag and filter caches, to make use of this characteristic to improve the efficiency of the filtering engine. The performance of the proposed engine has been examined by implementing a prototype system and testing it. Compared to the basic sequential filter comparison approach, our engine shows much better performance, and it gets better as the number of filters increases.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.334-336
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• 2004

Statechart는 매우 널리 쓰이고 있는 명세 언어이다. 현재는 UML에 포함되어 않은 사랑들이 구현하고자 하는 시스템의 명세에 Statechart를 이용하고 있다. Statechart 명세는 구현될 시스템의 설계도 역할을 하기 때문에 오류가 있을 경우 매우 치명적일 수 있으며, 반대로 시스템의 오류를 명세 단계인 Statechart 영세에서 찾아내게 되면 수정에 필요로 하는 비용과 시간의 손실을 최소화 할 수 있다. 본 논문에서는 하드웨어 검증 분야에서 사용되고 있는 Assertion Based Verification (ABV) 방법론을 Statechart 명세에 적용하여 시뮬레이션 등으로는 찾아내기 힘든 오류를 찾아낼 수 있음을 보였다.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.23 no.1
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• pp.6-10
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• 1987

The authors carried out an experiment to measure the hydrodynamic resistance of the gear and the efficiency of otter board of the midwater trawl, which is the same used in the former experiment in this series of studies. The whole resistance of the gear was measured by a 10 ton scale recording tension meter, and they were analyzed into the shearing force and the drag with relevant factors determined in the former experiments. The results obtained can be summarized as follows: 1. The whole drag of gear T(kg) and the drag of net R sub(N) (kg) can be expressed as T=2.15 v super(1.12). R sub(N)=1.96 v super(1.01) (v: towing speed in m/sec) 2. The formula of estimating the drag of net deduced by Koyama's method can be expressed as R sub(N)=4.3$\times$d/l$\times$abv 3. The shearing force and the drag of otter board is about 19 to 22% and 5 to 7% of the drag of net, respectively. Whereas, the shearing coefficient and the drag coefficient calculated by the resistance and the opening of gear are 1.5 and 0.42, respectively.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.17 no.1
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• pp.1-8
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• 1984

The author carried out an experiment to determine the resistance of trawl net aboard M/S Saebada, training ship of National Fisheries University of Pusan, 2,275 G/T and 3,600ps. Total tension loaded on warp were measured by the recording tension meter. Resistance of the net is estimated by subtracting the resistance of otter boards and warps from the total tension. Coefficient k and exponent n of the formula on the trawl net deduced by Koyama, $R_N=k\frac{d}{l}abv^n$ were calculated from the resistance of the net obtained. The results obtained are can be summarized as follows : 1. Six seamed net with two net pendant k=11, n=1.8 2. Eight seamed net with three net pendant k=11, n=1.8 3. Ten seamed net with three net pendant k=9, n=1.9 4. Ten seamed net with four net pendant k=9, n=1.9

• Asian-Australasian Journal of Animal Sciences
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• v.11 no.6
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• pp.718-724
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• 1998

Twelve gilts were used to investigate the effect of lysine to protein ratio (5.2 g lysine/100 g CP vs. 6.7 g lysine/100 g CP) in practical diets on nitrogen retention and the efficiency of utilization in growing pigs. Treatments involved 2 levels of dietary lysine (5.2 or 6.7 g/100 g CP) and 3 levels of dietary crude protein (11, 14 and 17% in diet). Nitrogen retention was greatest when pigs were fed the control diet containing 17% protein. Nitrogen retention progressively increased as dietary protein increased (p < 0.01), but it was not affected by lysine concentration (g/100 g CP). Apparent biological value (ABV, nitrogen retained/apparently digestible nitrogen) was estimated to be ~50% at the maximum nitrogen retention. ABV was not affected by lysine concentration, but declined (p < 0.05) as the dietary protein level increased. The efficiency of intake N used for maximum nitrogen retention was approximately 44%. One gram of lysine supported approximately 9 to 10 g apparent protein accretion (nitrogen retention ${\times}$ 6.25/lysine intake) in pigs fed control diets. The efficiency of lysine utilization for protein accretion was lower in pigs fed high-lysine diets (6.7 g lysine/l00 g CP) so that 1 g of lysine accounted for 7 to 8 g of protein accretion in these pigs (p < 0.01). The lysine required to support maximum nitrogen retention in pigs fed high-lysine diets was higher than that in pigs fed control diets, which suggests that lysine was over-fortified relative to crude protein, since practical diets can not be formulated without excess of some amino acids. In summary the concentration of 5.2 g total lysine/100 g CP in diet is more appropriate for corn-soybean diets than the commonly suggested the content of 6.7 g total lysine/100 g CP.

• Journal of the Korean Home Economics Association
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• v.46 no.3
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• pp.49-55
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• 2008

The purpose of this study was to investigate the effects of green tea extracts (GTE) on the fermentation properties of polyphenol-enriched beers. As such, the formation patterns of tannoid in beer with GTE were investigated at 3 different infusion times, while the ale and the lager beers fortified with GTE were analyze to ascertain effects on gravity, pH, yeast viability, total polyphenol, and tannoid during fermentation period. The results were as follows: 1) The formation of tannoid in beer with GTE in the tannometer; In reaction of GTE with polyvinylpyrrolidon (PVP), control lager beer peaked in the formation of tannoid at $70\;{\sim}\;80\;mg$ of PVP, the 1st extract exceeded the detection limit, the 2nd extract at $170\;{\sim}\;180\;mg$, while the third extract at $150\;{\sim}\;160\;mg$ of PVP. The GTE were slow in reacting with PVP, and their formation patterns were different from those of polyphenols from barley and hop. 2) Ale fermentation; The final alcohol content was 9.25% (ABV). The addition of GTE increased the yeast viability after 2 days and finally reached 52.3% from 30.9%. Total polyphenol in GTE beer increased by 1.5 times (p < .05). However, its tannoid contents increased by 6.4 times. 3) Lager fermentation; The final alcohol content was 5.93% (ABV). The effect of GTE on lager beer was minimal for all variables. However, total polyphenol of GTE beer increased by 1.4 times (p < .05). Its tannoid increased by 3.3 times (p < .05).