• 대한전기학회:학술대회논문집
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• 대한전기학회 1992년도 하계학술대회 논문집 A
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• pp.431-433
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• 1992

• Asian Pacific Journal of Cancer Prevention
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• 제13권4호
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• pp.1657-1662
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• 2012

Fucosyltransferase IV (FUT4) has been implicated in cell adhesion, motility, and tumor progression in human epidermoid carcinoma A431 cells. We previously reported that it promotes cell proliferation through the ERK/MAPK and PI3K/Akt signaling pathways; however, the molecular mechanisms underlying FUT4-induced cell invasion remain unknown. In this study we determined the effect of FUT4 on expression of matrix metalloproteinase (MMP)-12 induced by EGF in A431 cells. Treatment with EGF resulted in an alteration of cell morphology and induced an increase in the expression of MMP-12. EGF induced nuclear translocation of nuclear factor kB (NF-${\kappa}B$) and resulted in phosphorylation of $IkB{\alpha}$ in a time-dependent manner. In addition, ERK1/2 and p38 MAPK were shown to play a crucial role in mediating EGF-induced NF-${\kappa}B$ translocation and phosphorylation of $I{\kappa}B{\alpha}$ when treated with the MAPK inhibitors, PD98059 and SB203580, which resulted in increased MMP-12 expression. Importantly, we showed that FUT4 up-regulated EGF-induced MMP-12 expression by promoting the phosphorylation of ERK1/2 and p38 MAPK, thereby inducing phosphorylation/degradation of $I{\kappa}B{\alpha}$, NF-${\kappa}B$ activation. Base on our data, we propose that FUT4 up-regulates expression of MMP-12 via a MAPK-NF-${\kappa}B$-dependent mechanism.

• Smart Structures and Systems
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• 제17권3호
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• pp.431-444
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• 2016

This paper was written in the context of a benchmark study promoted by The Hong Kong Polytechnic University using data samples collected in an instrumented cable-stayed bridge. The main goal of the benchmark test was to study the identification of the bridge modes of vibration under different wind conditions. In this contribution, the tools developed at ViBest/FEUP for automated data processing of setups collected by dynamic monitoring systems are presented and applied to the data made available in the context of the benchmark study. The applied tools are based on parametric output only modal identification methods combined with clustering algorithms. The obtained results demonstrate that the proposed algorithms succeeded to automatically identify the modes with relevant contribution for the bridge response under different wind conditions.

• 대한한의학회지
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• 제17권2호
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• pp.303-310
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• 1996

The purpose of this study was to investigate effect of water extract of Carthami Flos on the proliferation of human cancer cell-lines. The effects of Carthami Flos on the proliferation of A431, HeLa, MOLT-4, K562 cells, Balb／c 3T3 cells, mouse thymocytes, splenocytes and human lymphocytes were estimated by MTT colorimetric assay. The results were as follows; 1. Carthami Flos did not effect A431, HeLa, MOLT-4, K562 cells. 2. The cytotoxicity of mitomycin C on K562 cells was increased by the combination of Carthami Flos. 3. Carthami Flos inhibited the proliferation of Balb／c 3T3 cells. 4. Carthami Flos stimulated the proliferation of thymocytes. 5. Carthami Flos stimulated the proliferation of splenocytes. 6. Carthami Flos stimulated the proliferation of human lymphocytes.

• Journal of Electrical Engineering and Technology
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• 제5권3호
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• pp.431-434
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• 2010

This paper presents the torque calculation method of a permanent magnet spherical motor. To calculate using the finite element method (FEM), three-dimensional (3D) FEM must be used. However, since the method requires excessive time and memory, an easier torque calculation method is hereby presented. In the proposed method, it is very important to obtain the approximation function of the torque profile curve. We present the approximation method of the torque profile curve and show that the torque calculation result can approximate the torque obtained by 3-D FEM.

• 전기학회논문지
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• 제62권3호
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• pp.431-436
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• 2013

A neutral section is installed around feeding substation(SS) and sectioning post(SP) that M phase and T phase are isolated in AC feeding system. Electric Train under "Notch-OFF" is operated by inertia within the neutral section. It causes disturbing the operation of electric trains for speed drop and driver's mistakes. A automatic changeover system with thyristor recently have taken under development. In the paper, it is introduced the configuration of train detection system and performance testing on automatic changeover system..

• Steel and Composite Structures
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• 제14권5호
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• pp.431-451
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• 2013

The Big Bang-Big Crunch (BB-BC) optimization algorithm is developed for optimal design of non-linear steel frames with semi-rigid beam-to-column connections. The design algorithm obtains the minimum total cost which comprises total member plus connection costs by selecting suitable sections. Displacement and stress constraints together with the geometry constraints are imposed on the frame in the optimum design procedure. In addition, non-linear analyses considering the P-${\Delta}$ effects of beam-column members are performed during the optimization process. Three design examples with various types of connections are presented and the results show the efficiency of using semi-rigid connection models in comparing to rigid connections. The obtained optimum semi-rigid frames are more economical solutions and lead to more realistic predictions of response and strength of the structure.

• 전력전자학회논문지
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• 제17권5호
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• pp.431-437
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• 2012

PV simulators are essential equipment for testing power conditioning systems (PCS) which are one of an important part in PV generator systems, for testing before shipment. High dynamic PV simulator is required since MPPT(Maximum Power Point Tracking) test procedure has been established by EN50530 regulation recently. Most high quality PV simulator prevailed in the market is linear type which however has low efficiency. This paper proposes design guide lines for the power stage and LCL type filter cooperating with a switching mode PV simulator that shows high efficiency and very low power consumption. Proposed theory is verified by experiment.

• Communications for Statistical Applications and Methods
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• 제27권4호
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• pp.431-443
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• 2020

The K-means clustering algorithm has had successful application in sufficient dimension reduction. Unfortunately, the algorithm does have reproducibility and nestness, which will be discussed in this paper. These are clear deficits for the K-means clustering algorithm; however, the hierarchical clustering algorithm has both reproducibility and nestness, but intensive comparison between K-means and hierarchical clustering algorithm has not yet been done in a sufficient dimension reduction context. In this paper, we rigorously study the two clustering algorithms for two popular sufficient dimension reduction methodology of inverse mean and clustering mean methods throughout intensive numerical studies. Simulation studies and two real data examples confirm that the use of hierarchical clustering algorithm has a potential advantage over the K-means algorithm.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2014년도 춘계학술발표대회
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• pp.431-434
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• 2014

최근 정보유출 피해사례가 빈번히 발생하고 있으며, 발생 건수 중 대부분이 내부자에 의한 고의 또는 실수로 발생하는 경우가 대부분이다. 이를 방지하기 위해 기관 및 기업에서는 다양한 보안 솔루션을 도입하여 구축해서 운영하고 있다. 그러나 독립적으로 보안솔루션이 운영 및 관리되기 때문에 상관분석의 어려움으로 통합적인 내부정보유출 모니터링이 불가능하다. 또한 제한된 리소스로 과도하게 발생하는 보안 이벤트를 모니터링하여 내부정보유출을 탐지하고 관리하기에는 어려움이 있다. 따라서 본 논문에서는 사용자 본인이 보안 정책에 위반되는 행위를 했을 시 "어떠한 목적으로 보안위반 행위를 하였는지" 파악하기 위해 소명절차를 이용한 내부정보유출 방지 관리 방안에 대해 연구하고자 한다.