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Assessment of Vascularization within Hydroxyapatite Ocular Implant by Bone Scintigraphy: Comparative Analysis of Planar and SPECT Imaging (Hydroxyapatite 안구보충물삽입술 후 골신티그라피를 이용한 섬유혈관증식 평가: 평면영상과 SPECT 영상에서의 비교)

  • Lim, Seok-Tae;Sohn, Myung-Hee;Park, Soon-Ah
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.6
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    • pp.475-483
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    • 1999
  • Purpose: Complete fibrovascular ingrowth within the hydroxyapatite ocular implant is necessary for peg drilling which is performed to Prevent infection and to provide motility to the ocular prosthesis. We compared planar bone scintigraphy and SPECT for the evaluation of the vascularization within hydroxyapatite ocular implants. Materials and Methods: Seventeen patients (M:F: 12:5, mean age; $50.4{\pm}17.5$ years) who had received a coralline hydroxyapatite ocular implant after enucleation surgery were enrolled. Patients underwent Tc-99m MDP planar bone and SPECT imaging by dual head gamma camera after their implant surgery (interval: $197{\pm}81$ days). Uptake on planar and SPECT images was graded visually as less than (grade 1), equal to (grade 2), and greater than (grade 3) nasal bridge activity. Quantitative ratio of implanted to non-implanted intraorbital activity was also measured. Vascularization within hydroxyapatite implants was confirmed by slit lamp examination and ocular movement. Results: All but three patients were considered to be vascularized within hydroxyapatite implants. In visual analysis of planar image and SPECT, grade 1 was noted in 9/18 (50%) and 6/18 (33%), respectively. Grade 2 pattern was 7/18 (39%) and 4/18 (22%), and grade 3 pattern was 2/18 (11%) and 8/18 (44%) respectively. When grade 2 or 3 was considered to be positive for vascularization, the sensitivity of planar and SPECT imaging were 60% (9/15) and 80% (12/15), respectively. In 3 patients with incomplete vascularization, both planar and SPECT showed grade 1 uptake The orbital activity ratios on planar imaging were not significantly different between complete and incomplete vascularization ($1.96{\pm}0.87$ vs $1.17{\pm}0.08$, p>0.05), however, it was significantly higher on SPECT in patients with complete vascularization ($8.44{\pm}5.45$ vs $2.20{\pm}0.87$, p<0.05). Conclusion: In the assessment of fibrovascular ingrowth within ocular implants by Tc-99m MDP bone scintigraphy, SPECT image appears to be more effective than planar scintigraphy.

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Association of Renal and Bladder Ultrasonography Findings with Urinary Tract Infection Recurrence, High-Grade Vesicoureteral Reflux, and Renal Scarring

  • Park, Hye Won;Jin, Hyeil;Jeong, Su Jin;Lee, Jun Ho
    • Childhood Kidney Diseases
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    • v.19 no.2
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    • pp.125-130
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    • 2015
  • Introduction: This study investigated whether renal and bladder ultrasonography (RBUS) findings performed in children with the first incidence of febrile urinary tract infection (UTI) can predict UTI recurrence, high-grade vesicoureteral reflux (high-grade VUR), or acquired renal scarring (aRS). Methods: In all, 917 children who were admitted to our hospital from January 2001 to October 2010, owing to the first incidence of febrile UTI were enrolled in this study. All children underwent RBUS during admission. The mean follow-up was 7.9 months (standard deviation $[SD]{\pm}13.3$). UTI recurrence rates were calculated according to various clinical parameters. By using bivariate and multiple logistic regression analyses, we determined whether age, sex, abnormal RBUS findings, abnormal dimercaptosuccinic acid renal scan findings, or RBUS findings parameters were predictive of UTI recurrence, high-grade VUR, or aRS. Results: On RBUS, hydronephrosis and congenital anomaly of the kidney and urinary tract significantly predicted UTI recurrence. A small kidney, hydroureter, hydronephrosis, cortical thinning, and increased parenchymal echogenicity significantly predicted high-grade VUR. However, their odds ratios (OR) are low compared to normal RBUS findings (recurrent UTI: OR 0.432 and 0.354 vs. 0.934, respectively, high-grade VUR: .019, 0.329, 0.126, 0.058, and 0.188 vs. 2.082, respectively). No RBUS findings significantly predicted aRS. Recurrent UTI, high-grade VUR, and abnormal RBUS findings significantly predicted aRS (OR of 4.80, 4.61, and 2.58, respectively). Conclusion: RBUS is necessary to exclude severe congenital renal scarring, obstructive uropathy, and renal abscess at the first incidence of febrile UTI and is helpful in determining the need for subsequent clinical imaging.

Diabetes Mellitus and HbA1c Levels Associated with High Grade Prostate Cancer

  • Ozbek, Emin;Otunctemur, Alper;Dursun, Murat;Sahin, Suleyman;Besiroglu, Huseyin;Koklu, Ismail;Erkoc, Mustafa;Danis, Eyyup;Bozkurt, Muammer
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2555-2558
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    • 2014
  • Pirpose: The aim of this study to analyze the association between history of diabetes mellitus (DM) with risk of prostate cancer (PCa) and cancer grade among men undergoing radical prostatectomy for PCa. Materials and Methods: 50 patients with DM and 50 patients without DM who undervent radical prostatectomy (RP) were included in the study. Age at biopsy, height, weight, digital rectal examination (DRE), pre-biopsy PSA levels, prostate volume, histopathologic diagnosis after surgery and gleason scores were collected data from all patients. Histologic material obtained at biopsy was given a Gleason score; tumours with a Gleason score ${\geq}7$ were considered high grade and <7 were considered low grade. Results: The mean age at the time of biopsy was 63.7 in patients with DM and 61.6 in patients without DM. Diabetic men had significantly lower PSA levels (p=0.01). Mean PSA level $7.04{\pm}2.85$ in patients with DM and $8.7{\pm}2.86$ in patients without DM, respectively. Also, diabetic men had higher RP tumor grade than men without DM (p=0.04). We found that HbA1c levels were higher in patients who have high grade prostate cancer (p<0.05). Conclusions: Diabetic men undergoing RP have lower PSA levels and have significantly higher grade PCa. We must be careful for screening PCa in patients with DM. Although the patients had lower PSA levels, they might have high grade disease.

Optimization of Ingredients Formulation in tow Grades Surimi for Improvement of Gel Strength (저급 수리미의 젤 강도 증강을 위한 첨가물의 최적화)

  • CHOI Young-Joon;LEE Ho-Soo;CHO Young-Je
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.32 no.5
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    • pp.556-562
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    • 1999
  • The increasing price of surimi has affected the economical benefits of surimi based food industry, To maintain gel strength in low grade surimi, the optimum formulation adding functional proteins to low grade surimi is required. The objective of this study was to develop the optimum formulation of ingredients in making gels in low grade surimi on the addition of functional non-muscle proteins to low grade surmi by measuring rheological properties of the gels. The rheological qualities of the cooked gels made with A and RA grade surimi on the effects of adding five kinds of starches (potato, wheat, waxy maize, corn and modified corn) and four kinds of functional proteins (bovine plasma protein, dehydrated egg white, soy protein isolate and whey protein concentrate) to the gels were evaluated, The gel styengths at cooking with A and RA grade surimi were decreased with increasing the added starches. The kind of starches added affected little the gel strengths in Rh grade surimi, while potato and corn starches decreased at the least in gel strengths of the gel made with A grade surimi with increasing the concentration of starches. The bovine plasma protein (BPP) significantly increased the gel strength, especially in RA grade surimi, but BPP decreased the whiteness of the gel. Therefore, the optimum content of BPP was up to $2\%$ because of the whiteness of the gels in RA grade surimi, The optimum formulation for the gel with RA grade surimi to satisfy the gel strength of 1000$\times$g and $78\%$ moisture was $40.9\%$ surimi, $9.1\%$ dehydrated egg white (DEW) and $0.9\%$ starch, while that with A grade surimi under the same condition was $37.9\%$ surimi, $6.6\%$ DEW and $3,4\%$ starch.

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The Relationship of Alexithymia and Somatic Symptoms in Elementary School Children (초등학교 고학년의 감정표현불능증과 신체화 증상과의 관계)

  • Jeong, Sun-Mi;Kim, Jin-Ho
    • Journal of the Korean Society of School Health
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    • v.22 no.2
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    • pp.125-135
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    • 2009
  • Purpose: This study is to identify the relations between alexithymia, emotional clarification, emotional expressiveness and somatic symptoms, and their effect on the elementary school students. Methods: This study targets 567 elementary school students and they are composed of 288 boy students and 279 girl students in 5th and 6th grade, and 283 in the 5th grade and 284 in the 6th grade. Results: In somatic symptoms, alexithymia, emotional clarification, and emotional expressivness, a significant difference is found. For the somatic symptoms and alexithymia, the subject in grade 5 show higher score than those in grade 6. For the emotional clarification, and emotional expressivness, the subjects in grade 5 show higher scores than those of grade 6. According to sex, only in emotional clarification, a significant difference is found between boys and girls and the girls show higher score that the boys. In looking at the correlations between alexithymia, emotional clarification and somatic symptoms, the somatic symptoms has positive correlations with alexithymia while it has negative correlations with emotional expressiveness. The alexithymia has negative correlations with emotional clarification and emotional expressiveness. It is found that the emotional clarification has positive correlations with emotional expressiveness. Conclusion: In respect to the effect of alexithymia, emotional clarification and emotional expressiveness on somatic symptoms, emotional alexithymia and emotional clarification have effect on somatic symptoms and emotional expressiveness has no effect on somatic symptoms.

General Feature and Ginsenoside Content of 6 years Old Ginseng (Panax ginseng C. A. Meyer) Root (6년근(年根) 인삼(人蔘)의 등급별(等及別) 품위(品位) 및 ginsenoside 함량)

  • Cho, Hyun-Kyung;Park, So-Hee;Jung, Chung-Sung;Jo, Jae-Sun
    • Journal of the Korean Society of Food Culture
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    • v.16 no.5
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    • pp.478-482
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    • 2001
  • This study was conducted to investigate the difference of general feature and ginsenoside content of 6 years old ginseng root among different grade of roots. Total weight of a 1st grade-6 years old ginseng root was 115.1g and weight, length, diameter and specific gravity of main root were 64.68g, 8.39cm, 3.31cm and 0.96, respectively. Main root of 1st grade ginseng root was larger in size and specific gravity and more heavy than that of End or 3rd grade of the roots. Though crude saponin contents were not so different among the different grade of roots, but ginsenoside Rb1, Rg1 and Re content were higher in 1st grade of root than that of 2nd or 3rd grade of root. Those ginsenosides were located mainly in periderm and cortex.

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A Study on the Relationship between Temperament and Mathematics Academic Achievement

  • Li, Mingzhen;Pang, Kun
    • Research in Mathematical Education
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    • v.11 no.3
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    • pp.197-207
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    • 2007
  • Based on a survey on 1620 students in primary school and secondary school., by adopting Eysenck Personality Questionnaire (EPQ), we got the following findings : 1. There is close relationship between emotionality characteristics of temperament and mathematics academic achievement of the subjects at Grade 5 (Primary 5), Grade 8 (Junior Secondary 2), and Grade 10 (Senior Secondary 2). Also there is close relationship between internal-external directivity characteristics of temperament and mathematics academic achievement at Grade 5 and Grade 8. While there is not close relationship between internal-external directivity characteristics of temperament and mathematics academic achievement at Grade 10; 2. There is close relationship between temperament types and mathematics academic achievement of the subjects from the three grades. Superior temperament, which benefit learning mathematics, are sanguine, sanguine-phlegmatic and phlegmatic; While inferior temperament types, which don't benefit learning mathematics, are choleric, melancholic and choleric-melancholic. With the rising of grade, temperament types of benefiting learning mathematics converts from external directivity emotion balance to balance of internal-external directivity emotion stability. While temperament of no benefiting learning mathematics converts from internal directivity emotion balance to balance of internal-external directivity emotion instability; 3. In mathematics education, students' temperament difference, which affects learning mathematics, should be recognized. Mathematics teachers should find out the best teaching ways, forms and methods which are suitable for student's temperament type, so that the students with different temperament types can gain better mathematics academic achievement.

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Study on the Trend Analysis according to Grade of G-SEED for University Facilities (대학시설의 녹색건축인증 등급별 득점경향에 대한 조사연구)

  • Ryu, Soo-Hoon;Kim, Hong-Min
    • Journal of the Korean Institute of Educational Facilities
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    • v.25 no.6
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    • pp.3-10
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    • 2018
  • This study analyzes the average acquisition ratio between the 1st and 4th grade and the distribution and characteristics of the acquisition between the assessment items based on the case of Green Building Certification System(GBCS) for the educational facilities on the university campus. By evaluating the difference between the best scored grade (Green 1st Grade) and the general grade (Green 4th Grade), we classified the cases where the difference between grades with little or big difference. By doing this, we were able to analyze the trend that were difficult to distinguish between difficult to score and an easy task. G-SEED should be used not only as a formal system for certifying certification, but also to provide environmentally-friendly technology for buildings as well as meeting market needs. To do this, it is necessary to further refine the evaluation criteria. In addition, it is necessary to establish a qualitative evaluation system by providing detailed criteria for items that are not distinguishable among grades. It is expected that this study will be used to improve the detailed evaluation items by analyzing trends in the average acquisition rate presented in this study.

A Study on a Ginseng Grade Decision Making Algorithm Using a Pattern Recognition Method (패턴인식을 이용한 수삼 등급판정 알고리즘에 관한 연구)

  • Jeong, Seokhoon;Ko, Kuk Won;Kang, Je-Yong;Jang, Suwon;Lee, Sangjoon
    • KIPS Transactions on Software and Data Engineering
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    • v.5 no.7
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    • pp.327-332
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    • 2016
  • This study is a leading research project to develop an automatic grade decision making algorithm of a 6-years-old fresh ginseng. For this work, we developed a Ginseng image acquiring instrument which can take 4-direction's images of a Ginseng at the same time and obtained 245 jingen images using the instrument. The 12 parameters were extracted for each image by a manual way. Lastly, 4 parameters were selected depending on a Ginseng grade classification criteria of KGC Ginseng research institute and a survey result which a distribution of averaging 12 parameters. A pattern recognition classifier was used as a support vector machine, designed to "k-class classifier" using the OpenCV library which is a open-source platform. We had been surveyed the algorithm performance(Correct Matching Ratio, False Acceptance Ratio, False Reject Ratio) when the training data number was controlled 10 to 20. The result of the correct matching ratio is 94% of the $1^{st}$ ginseng grade, 98% of the $2^{nd}$ ginseng grade, 90% of the $3^{rd}$ ginseng grade, overall, showed high recognition performance with all grades when the number of training data are 10.

Correlation Between Expression of ER, PR and C-erbB-2 Protein as Histologic Grade of Breast Cancer (유방암의 조직학적 악성도에 따른 에스트로겐 수용체(ER)와 프로게스테론 수용체(PR), 그리고 C-erbB-2 종양단백질 발현과의 상관관계)

  • Han, Kyung Hee;Kim, Tai Jeon
    • Korean Journal of Clinical Laboratory Science
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    • v.36 no.2
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    • pp.185-192
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    • 2004
  • Overexpressions of the estrogen receptors(ER), progesterone receptors(PR) and C-erbB-2 protein are important determiners of the response to chemotherapy in the breast cancer. For detecting ER, PR and C-erbB-2, immunohistochemistry are currently regarded as standard method. The purposes of this study compared to histologic grade and expression of the ER, PR and C-erbB-2 in breast cancer. We examined overexpression of ER, PR and C-erbB-2 protein in 84 breast carcinomas by using immunohistochemical stains. The following results were obtained. For histologic grade, 10 cases(11.9%) showed carcinoma in situ, 16 cases(19%) showed grade I, 36 cases (42.9%) showed grade II, and 22 cases(26.2%) showed grade III among the 84 test samples. The average positive rate ER and PR was 63%, 46% showed carcinoma in situ, 80%, 60% showed grade I, 64%, 41% showed grade II, 34%, 23% showed grade III, respectively. The induction of PR increased when induction of ER increased, thus showing significant relationship(p<0.05). The expression of C-erbB-2 protein was 9 cases(10.7%) in one positive(1+), 9 cases(10.7%) in two positive(2+), and 9 cases(10.7%) in three positive(3+). C-erbB-2 protein expression showed no statistical significance. In conclusion, ER and PR positive rates were inversely associated with histologic grades significantly(p<0.05). C-erbB-2 showed no significant difference with histologic grade. However ER, PR and C-erbB-2 showed significant relationship with each other(p<0.05). Therefore, these findings might be an important prognostic factor and might be arranged as a regular pathological examination in cases of breast cancer.

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