• Title/Summary/Keyword: A healthy adult

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Association of the RORA Gene Polymorphism and Seasonal Variations in Mood and Behavior (RORA 유전자 다형성과 기분 및 행동의 계절성 변동의 연관성)

  • Kim, Hae-In;So, Soo-Jung;Yang, Hee Jung;Song, Hyun Mi;Moon, Joung Ho;Yoon, Ho-Kyoung;Kang, Seung-Gul;Park, Young-Min;Lee, Seung-Hwan;Kim, Leen;Lee, Heon-Jeong
    • Sleep Medicine and Psychophysiology
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    • v.20 no.2
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    • pp.63-68
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    • 2013
  • Objectives: Several evidence has been suggested that the circadian gene variants contribute to the pathogenesis of seasonal affective disorder. In this study, we aimed to investigate the polymorphism in RORA (Retinoid-related orphan receptor A) gene in relation to seasonal variations among healthy young adults in Seoul, Korea. Methods: A total of 507 young healthy adult subjects were recruited by advertisement. Seasonal variations were assessed by the Seasonality Pattern Assessment Questionnaire (SPAQ). Single-nucleotide polymorphism in the RORA rs11071547 gene was genotyped by PCR in 507 individuals. Considering summer type as confounding factor, we conducted analysis 478 subjects except 29 subjects of summer type. The Chi-square test was conducted to compare differences between groups of seasonals and non-seasonals. Association between genotypes and Global Seasonality Score (GSS) were tested using ANCOVA (Analysis of covariance). Results: In this sample, the prevalence of SAD was 12.1% (winter type 9.3%, summer type 2.8%). There is no significant difference in genotyping distribution of RORA rs11071547 between groups of seasonals and non-seasonals. Global seasonality score (GSS) and scores of all subscales except body weight and appetite were not significantly different between the group with C allele homozygote and the group with T allele homozygote and heterozygote (p-value 0.138). Scores of body weight and appetite were significantly higher in group with C allele homozygotes. Conclusion: These results suggest that RORA gene polymorphism play a role in seasonal variations in appetite and body weight and is associated with susceptibility to seasonal affective disorder in some degree in the population studied.

Effects of the Experimental Vehicles on the Greenhouse Worker′s Work Load (비닐하우스 작업시 승용 농작업차의 노동부담 경감효과)

  • Choi, Jung-Hwa;Seol, Hyang;Ryu, Kwan-Hee
    • Korean Journal of Rural Living Science
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    • v.8 no.1
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    • pp.7-13
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    • 1997
  • In this study we examined the greenhouse worker's work load to test the efficiency of the developed vehicles (hand operated vehicle (HV), simple battery-powered autonomous vehicle (AV)). The subject of this study were healthy adult females who had experience in growing crops. We measured workers' heart rate, blood Pressure. rectal temperature, mean skin temperature, oxygen consumption and blood lactate level as a physiological index of work load. The results of this study are as follows : The test group using experimental vehicle showed the lower heart rate (mean$\pm$S.D. for HV, AV respectively 74$\pm$5, 75$\pm$3 beats/min, p<0.01) than the control group (84$\pm$8beat/min) not using experimental vehicle and the lower systolic blood Pressure (HV, AV respectively 109$\pm$8, 109$\pm$9 mmHg, p<0.01) than the control group (121$\pm$11 mmHg), and lower rectal temperature(HV, AV respectively 37.0$\pm$0.1, 36.8$\pm$0.2$^{\circ}C$, p<0.01) than the control group (37.0$\pm$0.2$^{\circ}C$), and the less oxygen consumption (HV, AV respectively 2.13$\pm$0.09, 1.66$\pm$0.52$m\ell$/kg/min, p<0.01) than the control group(2.43$\pm$0.12$m\ell$/kg/min), and the lower blood lactate level (HV, AV respectively 2.03$\pm$1.00, 1.66$\pm$0.52mmol, p<0.01) than the control group (2.43$\pm$0.12mmol). Judging from these results, these experimental vehicles for greenhouse workers can be confirmed as a useful tool. It is suggested that these vehicles would alleviate the peasant's syndrome including muscle fatigue and musculoskeletal disease usually caused by working in an uncomfortable posture.

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A STUDY ON MASTICATORY PERFORMANCE AND MUSCLE ACTIVITY IN REMOVABLE PARTIAL DENTURE WEARERS (자연치열자와 가철성 국소의치 장착자의 저작효율과 근활성도에 관한 비교 연구)

  • Paik, Jin;Park, Nam-Soo
    • The Journal of Korean Academy of Prosthodontics
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    • v.36 no.1
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    • pp.81-103
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    • 1998
  • The purpose of this study was to compare and evaluate the differences in masticatory performance, muscle activity, and patterns of occlusal contact between persons with natural dentition and removable partial denture wearers. Twenty healthy adult subjects with more than 28 teeth and thirteen removable partial denture wearers that classified Kennedy classification I was selected. The degree of pulverized rice and peanut was measured and analyzed by means of sieving method to compare the masticatory performance. For the muscle activity, EMG was recorded in selected muscles(Temporalis and masseter muscle) during mastication and resting state. The occlusal record in maximal intercuspation was taken with a silicone occlusal bite registration material for analysis of the patterns of occlusal contact. The obtained results were as follows: 1. When chewed peanuts, masticatory performance ratio at 10-sieve size was 81.31% in natural dentition group. In removable partial denture wearer, 27.01% without RPD and 69.09% with RPD. When chewed rice, 42.04%, 11.87%, and 21.58%, respectively. The differences of masticatory performance ratio between groups were statistically significant at the 0.05 level. 2. The mean EMG value in resting state was $1.06{\mu}V$ on temporal muscle, $0.98{\mu}V$ on masseter muscle in natural dentition group. In removable partial denture wearers, $1.13{\mu}V$ on temporal muscle, $1.05{\mu}V$ on masseter muscle without RPD and $1.11{\mu}V$ on temporal muscle, $1.04{\mu}V$ on masseter muscle with RPD. 3. The mean EMG value during mastication was $45.64{\mu}V$ in natural dentition group, and in removable partial denture wearers, $22.06{\mu}V$ without RPD and $31.01{\mu}V$ with RPD when chewed peanuts. When chewed rice, $45.24{\mu}V,\;25.53{\mu}V\;and\;32.14{\mu}V$, respectively. The differences of mean masticatory EMG value between groups were statistically significant at the 0.05 level. 4. The number of posterior occlusal contact point was 20.15 in natural dentition group and 11.92 in removable partial denture wearers. The area of perforated surface was $16.50mm^2$ in natural dentition group and $6.06mm^2$ in removable partial denture wearers. The area of contact surface was $78.93mm^2,\;51.52mm^2$, respectively. 5. The area of contact surface was effective to masticatory performance ratio in natural dentition group and removable partial denture wearers (p<0.05). From these results, it is concluded that in partially edentulous patient, masticatory efficiency can be improved by removable partial denture wearing, and for efficient mastication, tight occlusal contact surface shoud be maintained by maximum support that is provided from mucosa.

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EMG and Muscle Force of Intermittent Submaximal Constructions between Weight Lifters and Non-Weight Lifters (Weight Lifters와 Non-Weight Lifters 사이의 간헐적인 최대하 수축에서 근전도와 근력의 비교)

  • Sung, Paul S.
    • Physical Therapy Korea
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    • v.4 no.2
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    • pp.1-9
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    • 1997
  • Skeletal muscle fatigue is often associated with diminished athletic performance and inability to maintain an expected force output as a function of time. The purpose of this study was to compare the effect of duration of exercise on skeletal muscle fatigue between Weight Lifters(WL) and Non-Weight Lifters(NWL). There were twelve normal healthy adult volunteers, ranging in age from 18 to 35 years. The group consisted of six NWL and six WL. Randomized cross-over design was set up and work-rest cycle was 8 minutes work and 1 minute rest based on 15% MVC. Muscle fatigue was measured by the amount of force produced by the wrist flexor muscle and EMG amplitude over time. Repeated measures ANOVAs($2{\times}4$) were used to determine two types of subjects(WL, NWL) during four different duration of exercises(16, 32, 48, 64 minutes). The force decreased over time in NWL and WL, but there was no significant difference(F=2.83, p>0.05). However, the EMG amplitude increased in WL(0.8200) and NWL(0.6348). The WL exhibited an increase in EMG at the end of the period, especially at 48 minutes of exercises than did the NWL(F=9.58, p<.05). This suggests the WL were able to adjust to prolonged effort with adaptations in neural effect over time, resulting in higher EMG amplitude. That is, WL may be able to learn to recruit more motor units with training. It is important to the degree of neuromuscular fatigue and the time needed for recovery may differ considerably between WL and NWL, there is a need to plan proper strength training or rehabilitation protocols to match with the requirements in different characteristics of groups.

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A Study on Nitrogen Intake and Excretion in Young Korean Adult Women on Normal Diet (정상식이를 섭취하는 여대생들의 질소 섭취 및 배설에 관한 연구)

  • 김주연
    • Journal of Nutrition and Health
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    • v.20 no.2
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    • pp.90-103
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    • 1987
  • A study was conducted to measure nitrogen intake and excretion in young korean women on their normal diet and leading normal activity level. Dietary survey by food record, fecal and urinary samples were collected for 3 days in 19 healthy female college students in Korea. On one of the 3 days, duplicate of one-day diet was collected from each subjects. Mean daily intakes of energy and protein were calculated from food recorded. Duplicate diet samples and pooled fecal samples were analyzed for N content. Pooled urine samples were analyzed for total N, urea N, and creatinine content. Apparent N absorption, apparent N balance and urea N/creatinine N were calculated to evaluate protein nutritional status. The results obtained are summarized as following ; 1) Accordingly to food record, mean daily intakes of energy, protein, carbohydrate and far were 1535.2 $\pm$53.78Kcal, 55.95$\pm$2.97g(total nitrogen 8.95$\pm$0.45g), 254.13$\pm$10.31g and 39.24$\pm$2.76 g, providing 14.6%, 66.2%, 19.2% of total energy respectively. 2) Nitrogen intake by chemical analysis was 7.16$\pm$0.31g/day (protein 44.75$\pm$1.94kg/day) providing 82.39$\pm$4.58% of nitrogen intake by food record. The difference of total nitrogen intake between food record and chemical analysis in diets was significant(p<0.05). 3) Mean daily fecal nitrogen excretion was 1.38$\pm$0.10g and then mean apparent digesbility of protein was 80.53$\pm$5.21%. 4) Mean daily urinary nitrogen excretion, urea N excretion and creatinine excretion were 6.03$\pm$0.30g, 4.52$\pm$0.22g, and 0.88$\pm$0.04g respectively. Urinary urea nitrogen was 75.2$\pm$1.38% of total urinary nitrogen excretion and urinary nitrogen was 85.4$\pm$3.56% of total nitrogen intake by chemical analysis. 5) Mean urea N/creatinine N ration was 14.01$\pm$0.77. 6) Mean nitrogen balance was -0.244$\pm$0.33g/day. From the above results, it is concluded that the subjects in this study seem to be in marginal protein nutritional status and therefore should increase dietary protein intake.

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Convergence Study of Eating Together And Mental Health within 20-30's : Using 6th(2013-2015) Korea National Health and Nutrition Examination Survey(KNHANES VI) (우리나라 초기성인(20-39세)의 동반식사 유무에 따른 정신건강상태에 대한 융합적 연구 : 제 6기 국민건강영양조사(2013-2015))

  • Jung, Myung Sook;Song, Hye Young;Kim, Won Jeong
    • Journal of the Korea Convergence Society
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    • v.9 no.6
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    • pp.287-298
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    • 2018
  • This study, a second analysis research using raw data of the 6th Korea National Health and Nutrition Examination Survey(2013-015), places its purpose on examining risk factors for the mental health of the youth. With its target on 3,712 people in their twenties and thirties, it has used complex sample cross analysis to figure out the relationship between their mental health and eating habits. Also, it has carried out multiple logistic regression analysis for the purpose of grasping the youth's mental health risk factors. Under the circumstances, controlling the subjects' individual characteristics, the study has shown that males with their breakfast and dinner partners have lower possibilities of depression and suicidal thoughts. Meanwhile, in the case of females, their breakfast and lunch partners have played a key role in lowering their stress and suicidal thoughts. Given these results, the government will have to make all-out efforts to upgrade public places and spaces for the youth to eat together. All this will lead to their healthy eating habits and positive mental health. More specifically, it will have to create variable programs necessary for educating them to manage their diet and enjoy eating with other people.

Isolated Activation of the Upper Trapezius in Three Manual Muscle Testing Position : Convergence Study (세 가지 도수근력 검사 자세에서 상부 승모근의 독립적 수축 : 융합적 연구)

  • Ha, Sungmin
    • Journal of the Korea Convergence Society
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    • v.11 no.1
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    • pp.83-88
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    • 2020
  • The purpose of this study was to investigate the optimal position among three manual muscle tested positions for upper trapezius in which to obtain an isolated upper trapezius EMG signal for the normalization of upper trapezius muscle EMG activity. A total of 28 healthy adult men participated in the experiment. The UT (upper trapezius) and LS (levator scapulae) muscle activities were measured using the TeleMyo 2400T and analyzed using MyoResearch software. The muscle activity of the US and LS was measured by performing three manual muscle test positions for the upper trapezius. The UT/LS ratio during the S-MVIC was 80.25 and was significantly higher than that during the T-MVIC (76.50; p = 0.011) and the C-MVIC (60.95; p < 0.001). And, the UT/LS ratio during the T-MVIC and was significantly higher than that during the C-MVIC (p < 0.001). Based on the results of present study, we suggest a switch from T-MVIC to S-MVIC for the independent normalization reliability of upper trapezius EMG activity. The UT muscle strength or normalization test using S-MVIC will be able to measure muscle strength or activity of UT compared to previous measurement methods.

AN EXPERIMENTAL STUDY ON SUPEROXIDE DISMUTASE- AND CATALASE- ACTIVITY IN GINGIVAL TISSUES IN DIABETIC PATIENTS (당뇨환자의 치은조직내 Superoxide Dismutase와 Catalase의 활성도에 관한 실험적 연구)

  • Kim, Byung-Ok;Lee, Kang-Jin;Park, Joo-Cheol
    • Journal of Periodontal and Implant Science
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    • v.24 no.3
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    • pp.597-606
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    • 1994
  • Oxygen derived radicals($O_2\;^-$, $H_2O_2$, and $OH^-$) are thought to play a role in a lot of human diseases. And it has been believed that antioxidant enzymes such as superoxide dismutase(SOD) and catalase could protect the tissues from damage resulting from the oxygen derived free radicals. The purpose of this study was performed to investigate the activity of the SOD(CuZn- and Mn-SOD) and catalase in inflammatory gingival tissues and the correlation between boold glucose level and antioxidants and age in non-insulin dependent diabetes mellitus(NI- DDM) patients. For this study, the patients were classified into normal, inflammatory, and diabetic, and ten their papillary bleeding index(PBI) and gingival index were checked. Subjects consisted of 11 healthy patients with no inflammatroy gingiva, 20 adult periodontitis patients, and 8 diabetic patients, aged 33 to 66(average: 44.62). The blood glucose level of diabetic group was ranged from 120ml/dl to 160ml/dl(physical status 0 : averge : 135.67ml/dl). Gingival tissues were surgically obtained from the patients during periodontal surgery, extraction, and clinical corwn lenghening procedure. The activity of CuZn and Mn- SOD and catalase in the gingival tissues was measured by using UV-spectrophotometer by the same methods that Crapo et al. And Aebi did, respectively. The results were as follows : 1. The Mn-SOD activity was significantly lower in inflammatory group in comparison to normal group(P<0.05), and the activities of antioxidants in diabetic group were not significant in comparison to normal inflammatory group(P>0.05). 2. The activities of antioxidants showed little variation among individuals of different ages (P>0.05). 3. The higher blood glucose level was, the higher gingival index was(P<0.05). 4. There was no correlation between blood glucoe level and activity of antioxidant in inflammatory gingival tissues of NIDDM patients(P>0.05). In conclusion, these results, within the limits of the present experiment, suggest that the activity of Mn-SOD might reflect the inflammatory status of gingival tissue, and the activity of antioxidants was independent of blood glucose level of diabetic patients in physical status 0.

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Disease monitoring of Alaska pollock (Gadus chalcogrammus) based on growth stages (명태 (Gadus chalcogrammus)의 성장 단계별 질병 모니터링)

  • Kim, Kwang Il;Byun, Soon-Gyu;Kang, Hee Woong;Nam, Myung-Mo;Choi, Jin;Yoo, Hae-Kyun;Lee, Chu
    • Korean Journal of Ichthyology
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    • v.29 no.1
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    • pp.62-68
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    • 2017
  • The Alaska pollock (Gadus chalcogrammus) belongs to the family Gadidae; it is a cold water fish, and has been developed as a novel aquaculture species in Korea. In this study, we describe ongoing surveillance for aquatic animal pathogens based on growth stages. We investigated bacterial flora in rearing water, and monitored pathogens; we also analyzed histopathological traits of abnormal fish. In rearing water, the total bacterial counts were $2.1{\times}10^3cfu/mL$ and Vibrio spp. (52%) were predominant in the larvae stage. In the juvenile and adult stages, the total bacterial counts were $3.4{\times}10^3$ and $3.2{\times}10^2cfu/mL$, respectively (with Pseudomonas sp. as the predominant species; 90% and 52%). This result revealed that the bacterial flora in rearing water changed depending on the feeding types. No virulent-bacteria or problematic viruses (VHSV, viral hemorrhagic septicemia virus; NNV, nervous necrosis virus; MBV, marine birnavirus) were detected from outwardly healthy fish using either culture or PCR assay. Some juveniles (less than 5%) had gas bubbles on the gill lamellae, degeneration of the corneal epithelium, and choroid gland degeneration, suggesting that these symptoms were caused by external injury and secondary infection by opportunistic bacteria. Disease management is important to cope with disease emergence in the novel aquaculture species Alaska pollock.

Assessment of Working Posture Using RULA and REBA in Small Plants with Agricultural Products (소규모 작업장 작업자들의 인간공학적 평가 및 정량적 부하 평가 -한과작업장을 중심으로-)

  • Koo, Hye Ran;Kim, Hyo Cher;Shin, Yong Seok;Lee, Kyung Suk
    • Journal of Agricultural Extension & Community Development
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    • v.19 no.4
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    • pp.1021-1039
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    • 2012
  • Based on the ergonomic evaluation of workers in the domestic traditional Korean sweet manufacturer, one of the small scale agricultural product manufacturers, the purpose of this study is on estimating the specific works and muscles that have possibility of musculoskeletal disorder through an EMG experiment for quantitative evaluation. The method followed in an order: works that have musculoskeletal disorder risk were extracted through ergonomic assessment tools, RULA and REBA, and then EMG experiment on the postures was carried out with six healthy adult male patients. As an ergonomic evaluation result, work posture during the drying process had the greatest musculoskeletal disorder risk, and EMG activity in the cleansing work posture scored the highest among the drying, cleansing, and coating work postures. In particular in the drying work, relatively high EMG activities were shown in the two muscles in the lower body: biceps femoris muscle, and gastrocnemius, than any other muscles. Therefore, during the traditional Korean sweet workplace design in future, the workplace requires a posture that deeply bow wrist for a long time should be avoided.