• The Journal of Korean Institute of Communications and Information Sciences
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• v.18 no.6
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• pp.779-792
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• 1993

In a switching node or an ATM multiplexer of the ATM network, a good bandwidth utilization can be achieved by the priority control using the 1-bit(Cell Loss priority) in ATM cell header. In this paper, the mixed mechanism is proposed to make up for shortcomings of existing space priority control mechanisms and to decrease the loss probability of high priority cell and its performance is analyzed about the cell loss probability. To estimate the performance of proposed mixed mechanism, its cell loss probability is compared with those of non-priority mechanism, push-out mechanism and partial buffer sharing mechanism. The cell loss probability is analyzed using a M/D/1/N modeling and a 2-state MMPP/D/1/N modeling and also comparison between two modelings is made. To verify this result of numerical analysis, the computer simulation is performed for each mechanism using the simulation language, SIMSRIPT II.5.

• Nuclear Engineering and Technology
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• v.54 no.3
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• pp.1109-1114
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• 2022

The SMART (System-integrated Modular Advanced ReacTor) is an integral-type small modular reactor developed by KAERI (Korea Atomic Energy Research Institute). This paper discusses the feasibility and applicability of a 3D-based equivalent model using dynamic condensation method for seismic analysis of a SMART control rod drive mechanism. The equivalent model is utilized for complicated seismic analysis during the design of the SMART. While the 1D-based beam-mass equivalent model is widely used in the nuclear industry for its calculation efficiency, the 3D-based equivalent model is suggested for the seismic analysis of SMART to enhance the analysis accuracy of the 1D-based equivalent model while maintaining its analysis efficiency. To verify the suggested model, acceleration response spectra from seismic analysis based on the 3D-based equivalent model are compared to those from the 1D-based beam-mass equivalent model and experiments. The accuracy and efficiency of the dynamic condensation method are investigated by comparison to analysis results based on the conventional modeling methodology used for seismic analysis.

• Journal of the Korean Society for Precision Engineering
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• v.15 no.5
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• pp.128-136
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• 1998

A mathematical model for investigating the form generation mechanism in the centerless infeed grinding process is described. For 3-D modeling of form generation, contact points are assumed to be on least squares contact lines at the grinding wheel, regulating wheel, and work-rest blade. Using force and deflection analysis, the validity of this assumption is shown. Based on the 2-D simulation model developed in the previous work and the least squares contact line assumption, a 3-D model is presented. To validate this model, simulation results were compared with the experimental works. The experiments and computer simulations were carried out using three types of cylindrical workpiece shapes with varying flat length. The experimental results agree well with the simulation. It can be seen that the effect of flat end propagated to the opposite end through workpiece reorientation.

• Journal of Life Science
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• v.19 no.6
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• pp.770-780
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• 2009

A new photosensitizer, 9-Hydroxypheophorbide-a (9-HpbD-a), was derived from Spirulina platensis. We conducted a series of experiments, in vitro and in vivo, to evaluate the anticancer effect and mechanism of photodynamic therapy using 9-HpbD-a and 660 nm diode lasers on a squamous carcinoma cell line. We studied the cytotoxic effects of pheophytin-a, 9-HpbD-a, 9-HpbD-a red and 660 nm diode lasers in a human head and neck cancer cell line (SNU-1041). Cell growth inhibition was determined by using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assay. The effects of 9-HpbD was higher than those of 9-HpbD-a red or pheophytin-a in PDT. We then tested the cytotoxic effects of 9-hydroxypheophorbide-a (9-HpbD-a) in vitro. The cultured SNU-I041 cells were treated with serial concentrations of 9-HpbD-a followed by various energy doses (0, 0.1, 0.5, 3.2 J/$cm^{2}$) and by various interval times (0, 3, 6, 9, 12 hr) until laser irradiation, then MTT assay was applied to measure the relative inhibitory effects of photodynamic therapy (PDT). Optimal laser irradiation time was 30 minutes and the cytotoxic effects according to incubation time after 9-HpbD-a treatment increased until 6 hours, after which it then showed no increase. To observe the cell death mechanism after PDT, SUN-I041 cells were stained by Hoechst 33342 and propidium iodide after PDT, and observed under transmission electron microscopy (TEM). The principal mechanism of PDT at a low dose of 9-HpbD-a was apoptosis, and at a high dose of 9-HpbD-a it was necrosis. PDT effects were also observed in a xenografted nude mouse model. Group I (no 9-HpbD-a, no laser irradiation) and Group II (9-HpbD-a injection only) showed no response (4/4, 100%), and Group III (laser irradiation only) showed recurrence (1/4,25%) or no response (3/4, 75 %). Group IV (9-HpbD-a + laser irradiation) showed complete response (10/16, 62.5%), recurrence (4/16, 25%) or no response (2/16, 12.5%). Group IV showed a significant remission rate compared to other groups (p<0.05). These results suggest that 9-HpbD-a is a promising photosensitizer for the future and that further studies on biodistribution, toxicity and mechanism of action would be needed to use 9-HpbD-a as a photosensitizer in the clinical setting.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.52 no.3
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• pp.134-141
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• 2003

PID controllers with constant gains have been widely used in various control systems due to its powerful performance and easy implementation. But it is difficult to have uniformly good control performance in all operating conditions. In this paper, we propose a nonlinear variable PR controller with immune feedback mechanism. An immune feedback mechanism is based on the functioning of biological T-cells, they include both an active term, which controls response speed. and an inhibitive term, which controls stabilization effect. Therefore, the proposed nonlinear PID controller is based on immune responses of biological. immune feedback mechanism which is the cell mediated immunity and In order to choose the optimal nonlinear PID controller games, we also propose the tuning algorithm of nonlinear function parameter in immune feedback mechanism. To verify performance of the proposed algorithm, the speed control of nonlinear DC motor are performed. Front the simulation results, we have found that the proposed algorithm is more superior to the conventional constant fain PID controller.

• Transactions of the Korean Society of Automotive Engineers
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• v.5 no.6
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• pp.202-214
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• 1997

In automotive industries, one of major issues is the shifting shock, which is brought out when two clutches are engaged in an automatic transmission. The engagement and disengagement if two clutches means the variation of the D.O.F(degree of freedom) of system. Therefore to analyze the shifting performance, the variation of D.O.F should be considered in detail. Generally, the programs for analyzing the shifting transients have been developed as the problem-dependent codes because the artificial maris were usually used to indicate the change of shifting phase. To develop a software applicable to a general mechanism of transmissions, a self-determining algorithm of D.O.F must be applied. Through the experiences for the last several years, a generalized analysis software of shifting mechanism(so called by POTAS-MSM Version 2.0) has been developed. In this study, some major ideas of the software and the concept for the analysis of shifting characteristics are presented. In addition to that, this paper shows how to self -determine D.O.F of he multi-slipping systems using the stick-slip criterion on a single slipping mechanism. By using this software, the shifting characteristics of a vehicle are analyzed and compared with the experimental results.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.260-260
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• 2000

In this work, we have developed a 2 degree of freedom(DOF) motion simulator that can generate the sensation of motion in a 6 DOF space. The motion base has the DOF of roll and pitch, and the purpose of the motion base is to create the sensation of riding a vehicle in a 3D space by controlling the motion base. The dynamics of the mechanism was analysed and the optimal design of the motion base mechanism has been reached. The prototype motion base mechanism was developed and tested. The multi-axis motion controller(MMC) was used to control the two ac servo motors that drive the roll and pitch motion.

• Journal of the Semiconductor & Display Technology
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• v.20 no.4
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• pp.171-176
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• 2021

Die-to-wafer (D2W) hybrid bonding in the multilayer semiconductor manufacturing process is one of wafer direct bonding, and various studies are being conducted around the world. A noteworthy point in the current die-to-wafer process is that a lot of voids occur on the bonding surface of the die during bonding. In this study, as a suggested method for removing voids generated during the D2W hybrid bonding process, a flexible mechanism for implementing convex for die bonding to be applied to the bond head is proposed. In addition, modeling of flexible mechanisms, analysis/design/control/evaluation of static/dynamics properties are performed. The proposed system was controlled by capacitive sensor (lion precision, CPL 290), piezo actuator (P-888,91), and dSpace. This flexure mechanism implemented a working range of 200 ㎛, resolution(3σ) of 7.276nm, Inposition(3σ) of 3.503nm, settling time(2%) of 500.133ms by applying a reverse bridge type mechanism and leaf spring guide, and at the same time realized a maximum step difference of 6 ㎛ between die edge and center. The results of this study are applied to the D2W hybrid bonding process and are expected to bring about an effect of increasing semiconductor yield through void removal. In addition, it is expected that it can be utilized as a system that meets the convex variable amount required for each device by adjusting the elongation amount of the piezo actuator coupled to the flexible mechanism in a precise unit.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.51 no.8
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• pp.344-351
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• 2002

The proposed immune algorithm has an uncomplicated structure and memory-cell mechanism as the optimization algorithm which imitates the principle of humoral immune response. We use the proposed algorithm to solve parameter optimization problems. Up to now, the applications of immune algorithm have been optimization problems with non-varying system parameters. Therefore the usefulness of memory-cell mechanism in immune algorithm is without. This paper proposes the immune algorithm using a memory-cell mechanism which can be the application of system with nonlinear varying parameters. To verified performance of the proposed immune algorithm, the speed control of nonlinear DC motor are performed. The results of Computer simulations represent that the proposed immune algorithm shows a fast convergence speed and a good control performances under the varying system parameters.

• Journal of Microbiology
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• v.40 no.1
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• pp.33-37
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• 2002

An enzymatic reaction for the production of D-alanine from D-aspartic acid and pyruvate as substrates by a thermostable D-amino acid aminotransferase (D-AAT) was investigated at various conditions In the temperature range of 40-70$\^{C}$ and pH range of 6.0-9.5. The D-AAT was produced with recombinant E. coli BL21, which hosted the chimeric plasmid pTLK2 harboring the D-AAT from the novel thermophilic Bacillus sp. LK-2. The enzyme reaction was shown to follow the Ping Pong Bi Bi mechanism. The K$\_$m/ values for D-aspartic acid and pyruvate were 4.38 mar and 0.72 mM, respectively. It was observed that competitive inhibition by D-alanine, the product of this reaction, was evident with the inhibition constant K$\_$i/ value of 0.1 mM. A unique feature of this reaction scheme is that the decorboxylation of oxaloacetic acid, one of the products, spontaneously produces pyruvate. Therefore, only a catalytic amount of pyruvate is necessary for the enzyme conversion reaction to proceed. A typical time-course kinetic study skewed that D-alanine up to 88 mM could be produced from 100 mM of D-aspartic acid with a molar yield of 1.0.