• Title/Summary/Keyword: 9-hydroxy-4-methoxypsoralen

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Chemical Constituents of the Fruit of Citrus junos

  • Cho, Eun-Jung;Piao, Xianglan;Piao, Longzhu;Piao, Huishan;Park, Man-Ki;Kim, Bak-Kwang;Park, Jeong-Hill
    • Natural Product Sciences
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    • v.6 no.4
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    • pp.179-182
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    • 2000
  • Nine compounds were isolated from the fruit Citrus junos. Their structures were elucidated as 9-hydroxy-4-methoxypsoralen, auraptene, limonin, deacetylnomilin, cirsimaritin, narirutin, naringin, hesperidin and neohesperidin by physico-chemical evidences. 9-Hydroxy-4-methoxypsoralen and auraptene have not been reported from C. junos yet.

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Estrogenic Activity of Furanocoumarins Isolated from Angelica dahurica

  • Piao, Xiang-Lan;Yoo, Hye-Hyun;Kim, Hyun-Young;Kang, Tak-Lim;Hwang, Gwi-Seo;Park, Jeong-Hill
    • Archives of Pharmacal Research
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    • v.29 no.9
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    • pp.741-745
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    • 2006
  • In our efforts to discover novel phytoestrogens to treat menopausal symptoms, eleven furanocoumarins were isolated from Angelica dahurica and tested for their estrogenic activity on the Ishikawa cell line. Among the compounds tested, 9-hydroxy-4-methoxypsoralen and alloisoimperatorin showed strong abilities to induce alkaline phosphatase (AP) with $EC_{50}$ values of 1.1 and $0.8\;{\mu}g/mL$, respectively, whereas the other nine furanocoumarins were weakly or only slightly active.