• Microbiology and Biotechnology Letters
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• v.7 no.2
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• pp.75-89
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• 1979

One strain of Penicillium sp. (175-66-B), isolated from soil, was able to produce a substance that has a strong inibition activity against the Agkistrodon and Trimeresurus venoms. In this experiment, the chemical and biological properties of the sample were investigated. As an inhibitory substance, it was effective to the proteinase, hemorrhagic and lethal factors of Agkistrodon and Trimeresurus venoms, and also effective to several fractions of the proteinases and hemorrhagic factors of Agkistrodon halys blomhoffi venom. Moreover, in the addition of prednisotone, it was more effective for the cure of the mouse envenomated with the venom amount of two fold of MLD$_{100}$. This substance was very stable to the acid, alkali and heat. Its melting point was high enough to sublime at 222$^{\circ}C$ without any decomposition. This sample was easily dissolved only in hot water, but not in several organic solvents except for a little dissolution in elate. It did not have the chelating activity. It had very strong specificity to the snake venoms. but its activity was depressed by the addition of zinc or cupric salts. This sample had no acute toxicity to the mouse. Its chemical formula was $C_{16}$ $H_{12}$$N_2$ $O_{10}$ with the molecular weight of about 392. It has two epoxy groups and four carboxyl radicals, but amino, nitrite and nitrate radicals, unsaturated bonds and aromatic ring were not detected. Theuchemical configuration of this sample was suggested to be;

• KOREAN POULTRY JOURNAL
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• v.4 no.10 s.36
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• pp.34-46
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• 1972

1. 육추율 육성율 성계생존율 육추율 99.7$\%$는 1회 98.5$\%$, 2회 99.2$\%$, 3회 99.8$\%$, 4회 98.3$\%$ 5회 98.7$\%$와 근사하다. 육성율 평균 87.1$\%$는 1회 97.5$\%$, 2회 97.2$\%$, 3회 96.6$\%$, 4회 97.9$\%$에 비하여 10$\%$정도 낮으며 5회 89.7$\%$보다도 2.6$\%$ 낮은데 이는 근년 많이 발생하는 마렉병 및 백혈병이 주원인이며,(7회 검정계 부터 마렉병 예방접종)현 김포검정사 신축이 장마로 인하여 지연되므로서 더욱 임시육추사에서의 육성기간에 스트레스를 받았기 때문이며 성계생존율은 평균 75.3$\%$이며, 1회 80.3$\%$, 2회 84.8$\%$, 3회 71.8$\%$, 4회 87.3$\%$, 5회 71.4$\%$ 이었다. 이를 폐사원인별로 보면 세균성 질환으로 인한 폐사가 전체폐사수의 8.9$\%$ 병독(마렉병 및 백혈병)이 61.5$\%$원충 0.7$\%$ 대사장애 9.2$\%$ 생식기장애 3.4$\%$ 내장파열(간파열 탈항등) 5.7$\%$ 곰팡이 1.1$\%$ 기타(복막염 장염등) 9.5$\%$로 마렉병 및 백혈병이 주인이며 이를 검정각회별로 보면 1.2회 32.3$\%$, 3회 43.3$\%$, 4회 41.3$\%$, 5회 56.2$\%$, 6회 61.5$\%$로 매년 증가하고 있다. 2. 성성숙일령 전체평균 155.9일로 가장 빠른 구는 4구의 144일이고 가장 늦은 구는 23구의 166일이며 1일 189.2일, 2회 181.2일 보다 30일 정도 빨라진 것은 1.2회 검정은 산란율 50$\%$ 연2일 산란한 전일로 계산하였으며 3회 검정부터는 산란율 50$\%$에 달한 일령으로 계산하였기 때문이다. 3. 산란율 산란지수 산란율 평균 64.6$\%$이고 최상위구는 77.1$\%$, 최하위구는 52.8$\%$이며 유색품종 평균산란율은 58.4$\%$ 백색품종은 66.6$\%$이며 성성숙일령이 빨라짐에 따라 전체산란율은 약간 떨어지고 있다. 산란지수-평균은 189.7개로 200개 이상 산란한 상위군이 모두 성계생존율이 높은 구임을 알 수 있다. 4. 사료요구율 전체평균 2.8로 1회 3.54, 2회 3.1., 3회 3.98 4회 2.87, 5회 2.83으로 점차 개선되어 가고 있으며 유색품종의 사료요구율 평균은 3.3이었다. 5. 난평균중량 평균 58.4g로 최상위구는 60.8g, 최하위구는 56.6g 이며 국산계의 평균난중은 57.9g 외국제 평균난중 58.6g이었다. 6. 체중 평균체중은 300일령 2,117.g, 500일령 2,207이며 유색품종은 300일령 2.6160g, 500일령 2.656.7g이었다. 7. 사료 섭취량 사료섭취량 평균은 1일수당 육추기 33.6g, 육성기 68.5g, 산란기 109.9g이었다. 8 경제성 총수입은 2,539,799 으로 전체수입의 85.3$\%$가 계란수입이고, 폐계 수입은 14.7$\%$이다. 지출은 총계 1,854.517원으로 전체 지출의 92.5$\%$가 사료비, 7.5$\%$가 초생추대이었다. 9. 후기 마렉병 백신이 71년 중반기부터 수입되므로써 마렉병 예방접종을 하지 못하므로서 전체 폐사 수의 61.5$\%$를 차지하는 많은 피해를 보았다.

• Journal of dental hygiene science
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• v.14 no.2
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• pp.248-255
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• 2014

The objective of the paper is to analyze the extent to which elementary school students acquired, perceived, and practiced oral health knowledge provided by an elementary school-based oral health clinic (SBOHC). It is respectively investigated by gender and year of school. The paper will be relevant for developing specified oral health programs in elementary SBOHCs. By choosing three elementary schools that operate SBOHC in the school district of Daejeon Metropolitan City from April 11 to April 30, 2013, a self-administered questionnaire was given out to be answered directly by 350 students in the 4th, 5th, and 6th grades and their responses were collected. Of the collected responses, 326 responses were explored by using the SPSS 12.0. Those students' scores of oral health knowledge are found to be statistically meaningful for school year, not for gender. In them are included correct tooth brushing time, dental caries symptoms, gum disease symptoms, and correct tooth brushing method. Change in tooth brushing method after oral health education showed the statistically meaningful difference for gender and school year. In conclusion, every SBOHC should develop a variety of specified educational programs that depend on gender and grade in each elementary school.

• Journal of the Korean Society of Food Science and Nutrition
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• v.40 no.7
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• pp.928-934
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• 2011

Nutritional compositions of acorn crude starch were analyzed according to country of origin, especially the mineral and sugar contents. Regarding the three kinds of starch of domestic (South Korea, KAS), Chinese (CAS), and North Korea (NAS) origins in the Korean market, NAS had the lowest moisture content as well as the highest contents of crude protein, crude fat, and carbohydrate. Regarding mineral contents, NAS contained the highest amounts of magnesium, calcium, sodium, potassium, and phosphorous, whereas CAS contained the highest iron and zinc contents. There were no significant differences in acidity and pH. Analysis of the monosaccharide contents of the starches showed that glucose was the highest in KAS while sucrose was the highest in CAS. The Hunter color L value was the lowest in NAS, whereas a and b values were the lowest in CAS. Total phenolic content was the highest in NAS. NAS had the highest DPPH and hydroxyl radical scavenging activities ($IC_{50}$: 47.0 mg/mL for DPPH, 0.038 mg/mL for hydroxyl) whereas KAS had similar DPPH ($IC_{50}$: 73.7 mg/mL for CAS, 86.8 mg/mL for KAS) and hydroxyl radical activities ($IC_{50}$: 0.041 mg/mL for CAS, 0.044 mg/mL for KAS) as compared to CAS.

• Journal of agricultural medicine and community health
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• v.27 no.2
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• pp.35-54
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• 2002

This study was performed to investigate the task status and performance improvement plan of dental hygienists of Health Centers and Subcenters. The Data collected by self-administered Questionnaire survey of 203 dental hygienists of Health Centers and Subcenters located in Gyeongsangbuk-do were analyzed. The major results are as follows: For the degree of satisfaction in tasks, 73.9% of dental hygienists of Health Centers and Subcenters felt proud, 52.2% felt overwork, 32.0% hoped transferring to other worksite and the major reason of transferring was lack of promotion opportunity in officials of dental hygiene department. Dental hygienists received job education in addition continuous job education in last 3 years were 47.3%, 19.2% of dental hygienists performed the special dental health program for residents in last 3years. Almost half(53.7%) of dental hygienists replied that dental hygienists who were not engaged in dental health tasks should be engaged in dental health tasks. The major dental hygienic tasks performed by dental hygienic officials were support for dental treatment(41.6%). Dental hygienic officials answered that dental health tasks, school dental health program, vertical dental health program should be conducted as important tasks in order. And they replied that the most serious problem of dental hygienic tasks was not conducting dental health affairs due to 'lack of dental doctor'(40.9%), 'lack of concern for dental health tasks'(26.4%), and 'lack of budget and personnels for dental tasks'(19.0%), and the most important thing to improve dental hygienic tasks was 'posting dental hygienists in ministry of health and welfare(MOHW) and province', 'securing of budget and personnels for dental health tasks'.

• Research in Community and Public Health Nursing
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• v.1 no.1
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• pp.172-173
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• 1989

본 연구는 전국의 보건진료원이 하는 업무를 분석하여 우리나라 보건진료원 제도 정착에 도움을 주는 기초자료를 제공하는 연구의 일환으로 강원도 지역에서 실시하였다. 연구대상은 강원도에 있는 보건진료원 전수로 하였고 이중 응답자수는 108명이었다. 연구도구는 문헌과 간호교육자들에 의해 작성 된 구조화된 설문지를 사용하였으며 수집된 자료는 SPSS를 이용하여 빈도, 백분율, 평균 및 피어슨 상관계수를 구하였고 유의성 검정을 위해서 t-test, ANOVA의 통계방법을 사용하였다. 본 연구결과를 통하여 얻은 결론은 다음과 같다. 1) 조사대상자인 보건진료원의 평균 연령이 31.5세이며 과반수의 보건진료원이 30세 미만 이었고 기혼자가 마혼자보다 약간 많았다. 보건진료원의 반수 이상이 현재 가족과 동거하고 있었고 학력은 3년제 간호전문대학 졸업자가, 경력은 3년 미만인 사람이 대부분이었으며 종교를 가진 사람이 대부분 이었으며 종교를 가진 사람이 안가진 사람보다 더 많았다. 또한 보건진료원의 근무지역 조건은 대부분이 을지에서 근무하고 있었고 대부분의 보건진료원이 신축된 보건진료소 시설에서 업무를 수행하고 보건진료소 내의 숙소에서 거주하는 것으로 냐타났다. 2) 보건진료원이 담당하는 평균 주민수는 1,660.8명 이었으며 과반수 정도의 보건진료원이 $501\sim1,000$명이 이상적인 적정 담당 주민수라고 생각하고 있었다. 강원도 주민의 연평균 보건진료소 이용자수는 4,099.3명 이었고 이용 주민수가 5,000명 이상인 보건진료소도 11개소 12.9 %나 되었다. 3) 보건진료소 사업대상지역 내에 있는 보건 의료기관은 약방 및 약종상이 62.1 %로 가장 많이 분포되어 있었고 보건지소도 16 %나 사업대상지역 내에 함께 있는 것으로 나타났다. 지역주민의 보건의료기관 이용은 보건진료소가 59.0 % 로 지역주민이 가장 많이 이용하고 있었고 보건 진료원이 가장 많이 이용하는 의뢰기관은 뱅 의원이 66 %, 보건소가 36.4 %로 나타났다. 또한 보건진료소의 보건의료기관과의 협조관계는 보건소와는 과반수 정도가 잘 협조하고 있다고 응답 한 반면 보건지소와 잘 협조하고 있다고 응답한 율은 37.6 % 밖에 안되었다. 4) 보건진료원이 업무영역 수행 정도를 살펴 보면 5점 만점에 통상질환관리가 3.69점, 사업 운영 관리 및 지도는 3.45점, 모자보건 및 가족계획은 3.28 점, 지역사회 조직 및 개발은 3.27 점, 보건정보체계 개발 및 수집은 3.17 점, 사업 계획 수립은 3.14 점, 지역사회 보건관리는 3.13 점의 순으로 나타났다. 보건진료원의 업무영역을 l 일 8 시간으로 하여 l 주 44 시간을 기준으로 측정하면 통상질환관리 18.56시간, 지역사회 보건관리 5.67 시간, 모자보건 및 가족계획 5.52 시간, 사업 운영관리 및 지도 4.10시간, 지역사회 조직 및 개발 3.05 시간, 보건정보체계 개발 및 수집 2.94 시간, 사업계획 수립 2.89시간의 순으로 나타났다. 5) 보건진료원의 업무영역별 수행 소요시간의 상판판계를 살펴보면 지역사펴 조직 및 개발을 위 해 소요한 시간은 사엽계획 수립 소요시간 및 보건정 보체계 관리 소요시간과 순상관관계를, 사업 계획 수립 소요시간은 지역사회 보건관리, 모자보건 및 가족계획 관리 소요시간 및 보건정보체제 관리 소요시간과 순상관관계를 나타냈다. 또한 통상질환관리 소요시간은 지역 사회 조직 및 개발, 사업계획 수립, 지역사회 보건관리와 모자보건 및 가족계획 관리, 사업운영 관리 및 지도, 보건정보체계 관리 소요시간과 역상관관계를 나타내었다. 6) 보건진료원의 총 업무수행 정도를 잘펴보면 업무수행 점수의 평균은 87.5점이었으며 보건진료원의 근무지가 병지이고 보건진료소의 시설상태가 나쁜 경우 업무수행 점수가 높은 것으로 나타났으며 업무수행 정도와는 별 차이가 없었다.

• Progress in Medical Physics
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• v.19 no.2
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• pp.89-94
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• 2008

TomoTherapy has a merit to treat cancer with Intensity modulated radiation and combines precise 3-D imaging from computerized tomography (CT scanning) with highly targeted radiation beams and rotating beamlets. In this paper, we comparing the dose distribution between TomoTherapy and linear accelerator based intensity modulated radiotherapy (IMRT) for 10 Head & Neck patients using TomoTherapy which is newly installed and operated at National Cancer Center since Sept. 2006. Furthermore, we estimate how the homogeneity and Normal Tissue Complication Probability (NTCP) are changed by motion of target. Inverse planning was carried out using CadPlan planning system (CadPlan R.6.4.7, Varian Medical System Inc. 3100 Hansen Way, Palo Alto, CA 94304-1129, USA). For each patient, an inverse IMRT plan was also made using TomoTherapy Hi-Art System (Hi-Art2_2_4 2.2.4.15, TomoTherapy Incorporated, 1240 Deming Way, Madson, WI 53717-1954, USA) and using the same targets and optimization goals. All TomoTherapy plans compared favorably with the IMRT plans regarding sparing of the organs at risk and keeping an equivalent target dose homogeneity. Our results suggest that TomoTherapy is able to reduce the normal tissue complication probability (NTCP) further, keeping a similar target dose homogeneity.

• The Korean Journal of Nuclear Medicine Technology
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• v.20 no.1
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• pp.42-46
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• 2016

Purpose Mammography is the most widely used scan for the early diagnosis since it is possible to observe the anatomy of the breast. however, The sensitivity is markedly reduced in high-risk patients with dense breast. Molecular Breast Imaging (MBI) sacn is possible to get the high resolution functional imaging, and This new neclear medicine technique get the more improved diagnostic information through It is useful for confirmation of tumor's location in dense breast. The purpose of this study is to evaluate the usefulness of MBI for tumor diagnosis in patients with dense breast. Materials and Methods We investigated 10 patients female breast cancer with dense breast type who had visited the hospital from September 1st to Octorber 10th, 2015. The patients underwent both MBI and Mammography. MBI (Discovery 750B; General Electric Healthcare, USA) scan was 99mTc-MIBI injected with 20 mCi on the opposite side of the arm with the lesions, after 20 minutes, gained bilateral breast CC (CranioCaudal), MLO (Medio Lateral Oblique) View. Mammography was also conducted in the same posture. MBI and Mammography images were compared to evaluate the sensitivity and specificity of each case utilizing both image and two images in blind tests. Results The results of the blind test for breast cancer showed that the sensitivity of Mammography, MBI scan was 63%, 89%, respectively, and that their specificity was 38%, 87%, respectively. Using both the Mammography and MBI scan was Sensitivity 92%, specificity 90%. Conclusion This research has found that, The tumor of dense tissue that can not easily distinguishable in Mammography is possible to more accurate diagnosis since It is easy to visually evaluation. But MBI sacn has difficulty imaging microcalcificatons, If used in conjunction with mammography it is thought to give provide more diagnostic information.

• Korean Journal of Ecology and Environment
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• v.49 no.2
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• pp.89-101
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• 2016

To elucidate occurrence patterns of $C_4$ plants in agroecosystems, we surveyed flora inside fields and embankments in 222 sites in farming lands in summer and fall, 2013. We also observed Kranz anatomy and analyzed carbon stable isotope to classify photosynthesis types. Our study observed total 54 species of $C_4$ plants in 33 genera and 9 families of vascular plants besides cultivated crops occurring in farming fields. The most common species was Portulaca oleracea L. followed by Digitaria ciliaris and Echinochloa crusgalli (L.) P. Beauv. var. crusgalli among the $C_4$ plants. The ratios of $C_3$ and $C_4$ species number to total number of species tended to maintain constant regardless of survey times and habitat types. The proportion of $C_4$ species to the total number of species were more influenced by the number of $C_3$ species than those of other types in the surveyed sites. Sizes of cultivation areas did not affect the proportions of $C_4$ plants. Increasing number of simultaneous weeding methods, especially with cutting method, appeared to decrease the number of $C_3$ plants. On the other hand, as the number of cultivated crops increased, both $C_3$ and $C_4$ plants increased but the proportions of $C_4$ species remained. We interpret our results that proportion of $C_4$ species in agroecosystems, appear to be dependent on the number of $C_3$ species, which in turn, appear to be affected by cultivation methods.

• Journal of the Korean Society of Marine Environment & Safety
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• v.15 no.2
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• pp.79-89
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• 2009

For preliminary diagnosis on current fishing ground environment and basic information for establishment of effective and rational management policy in fisheries resources protection area, water and sediment quality and changes of total area in the 10 marine protection areas designated for fisheries resources management in Korea were assessed. Results showed that environmental quality in these areas has been degraded by pollution sources, coastal utilization and development stress, etc. The pattern and degree of contamination differed by protection areas, suggesting that it is necessary for optimum environmental management plan considering the regional characteristics. The total designated area of protection areas in 2003 changed by $-22.9{\sim}2.4%$, on average -6.4%, compared with the first year of designation; Wando-Doam Bay showd the highest increase rate (2.4%), and Hansan Bay has the highest decrease rate (-22.9%) Decrease rate of land and sea in total area showd 6.1% and 6.6%. An integrated management of environmental data in protection areas is required for systematic assessment. Therefore, the suitable environmental and information management is needed specifically considering the environment characteristics such as development and utilization conditions of land and sea area Furthermore, bemuse urbanization and industrialization threats the junctions of the protection areas, authorized ministry (MIFAFF) should develope and establish monitoring and management procedures based on the related laws.