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Motor Evoked Potentials Study of the Facilitation and Reciprocal Inhibition Induced by Motor Imagination in the Thumb Muscles (무지근육에서 상상의 운동과 연관된 촉진과 억제에 관한 운동 유발 전위 검사)

  • Yang, Hyun Duk;Son, Il Hong;Suk, Seung Han;Lee, Sung Soo
    • Annals of Clinical Neurophysiology
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    • v.5 no.2
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    • pp.187-191
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    • 2003
  • Purpose: MEPs elicited by transmagnetic stimulations of the motor cortex are facilitated by voluntary muscle contraction. We evaluated the effects of the imagination of the movements on latencies of MEPs and reciprocal inhibition by using transmagnetic stimulations. Methods: Twenty two healthy volunteers(eight men and fourteen women) were studied. TMSs were delivered at rest and during imagining abducting or adducting right thumb. A stimulator with a round coil and a fixed intensity of 80% of maximum was used to evoke MEPs. MEPs were evoked by magnetic stimulations over the scalp and cervical spine(C7-T1), and central motor conduction times(CMCT) were calculated by subtracting the latency of compound muscle action potentials(CMAPs) obtained by stimulating over the cervical spine from that obtained by stimulating over the scalp. The motor evoked potentials were recorded from right abductor pollicis brevis muscle(APB) and adductor pollicis muscle(AP) simultaneously. Results: Imagination of abduction resulted in a shortened latency of the CMAPs in APB, and a prolonged latency in AP. Imagination of adduction resulted in a shortened latency in AP, and a prolonged latency in APB. But the imagination caused no significant change in the latency of CMAPs elicited by stimulation over cervical spine. Therefore, the changes of the CMCTs account for these latency changes with imagination of movement. With the imagination of abduction, there are significant reduction of the CMCT's in APB(10.8%) and prolongation in AP(5.8%). On the other hand, with the imagination of adduction, prolongation of the CMCT's in APB(7.3%) and reduction in AP(5.9%) were observed. Conclusion: These findings indicate that imagination of muscle contraction increases the excitability of the human corticospinal system. Reciprocal inhibition may be accountable for the prolonged latency in the antagonist muscle.

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Shelf-Life Extension of Sing Sing Hoe (Fresh Sliced Raw Fish) by Frozen Storage (냉동저장을 통한 싱싱회 저장기간 연장에 관한 연구)

  • Park, Jin-Il;Yoon, So-Mi;Yoon, Ho-Dong;Park, Hee-Yeon;Byun, Han-Seok;Jang, Mi-Soon
    • Food Science and Preservation
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    • v.16 no.6
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    • pp.824-829
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    • 2009
  • Changes in pH, viable microbial count, chemical freshness, texture, and sensory qualities of Sing Sing Hoe (SSH, fresh-sliced raw fish) were measured over 15 days at $4^{\circ}C$, $-20^{\circ}C$, and $-80^{\circ}C$. The initial pH of SSH was 6.25 at all three storage temperatures, and pH increased slightly after 12 days to pH 6.48 and pH 6.55 at $-20^{\circ}C$ and $-80^{\circ}C$, respectively. The range in viable cell count was 104-106 CFU/g, regardless of storage temperature. The initial content of volatile basic nitrogen (VBN) was 5.8 mg/100 g and became 8.2 mg/100 g or less, and 7.9 mg/100 g or less after 15 days at $-20^{\circ}C$ and $-80^{\circ}C$, respectively. However, pH and VBN values increased significantly after 3 days of storage at $4^{\circ}C$. At this temperature, the K-value was 22.3% after 6 days and 40% or more after 15 days. At $-20^{\circ}C$, the K-value was 9.6% or less after 6 days and 21% or less after 15 days of storage. At $-80^{\circ}C$, the K-value was 8.5% or less after 9 days and 20% or less after 15 days of storage. Compared with the K-value of live fish muscle (10%), freshness similar to that of live fish was maintained for 6 days under both $-20^{\circ}C$ and $-80^{\circ}C$ storage conditions. There was no significant change in texture during storage of SSH at $-20^{\circ}C$ or $-80^{\circ}C$, but SSH stored at $4^{\circ}C$ showed a decrease in texture quality during storage. Sensory scores were high for material stored for up to 3 days at $4^{\circ}C$ and 6 days at $-20^{\circ}C$ or $-80^{\circ}C$. The overall freshness of SSH was maintained for up to 6 days, in comparison with fresh-sliced raw fish, under both frozen storage conditions.

Asthma-COPD Overlap Syndrome: What We Know and What We Don't

  • Sin, Don D.
    • Tuberculosis and Respiratory Diseases
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    • v.80 no.1
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    • pp.11-20
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    • 2017
  • Approximately one in four patients with chronic obstructive pulmonary disease (COPD) have asthmatic features consisting of wheezing, airway hyper-responsiveness or atopy. The Global initiative for Asthma/Globalinitiative for chronic Obstructive Lung Disease committee recently labelled these patients as having asthma-COPD overlap syndrome or ACOS. ACOS also encompasses patients with asthma, ${\geq}40$ years of age, who have been cigarette smokers (more than 5-10 pack years) or have had significant biomass exposure, and demonstrate persistent airflow limitation defined as a post-bronchodilator forced expiratory volume in 1 second ($FEV_1$)/forced vital capacity of <70%. Data over the past 30 years indicate that patients with ACOS have greater burden of symptoms including dyspnea and cough and show higher risk of COPD exacerbations and hospitalizations than those with pure COPD or pure asthma. Patients with ACOS also have increased risk of rapid $FEV_1$ decline and COPD mortality. Paradoxically, experimental evidence to support therapeutic decisions in ACOS patients is lacking because traditionally, patients with ACOS have been systematically excluded from therapeutic COPD and asthma trials to maintain homogeneity of the study population. In this study, we summarize the current understanding of ACOS, focusing on definitions, epidemiology and patient prognosis.

The Impact of the United States Fashion on Korean Fashion in 20th Century

  • Oh, Keunyoung;Choi, Jeongwook
    • Journal of Fashion Business
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    • v.21 no.3
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    • pp.80-92
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    • 2017
  • Fashion trend is more than a social phenomenon that multitudes of people accept as popular styles of clothing. The purpose of this study was to understand the influence of fashion trend over time and distance. Geographically thousands of miles apart, the U.S. has strongly influenced fashion in Korea, revealed by references and historic depictions collected from literature and web sites. Results of the study are summarized as five issues: First, emergence of female missionaries from the U.S. American missionaries working in the late Great Korean Empire performed a significant role importing Western culture to Korea. Second, as opportunities of education increased, women studying abroad introduced Western fashion to Koreans when they returned to Korea. They were more open to Western culture than other Koreans and moderately harmonized their Korean sentiment and Western culture, mitigating cultural shock and enabled other Koreans to accept Western culture. Third, the effect of fashionistas on media. Singers working for U.S. armies stationed in Korea and movie stars appearing in Hollywood movies profoundly affected Korean pop culture and fashion trends in Korea. Fourth, following First Lady Jacqueline Kennedy of the U.S. She was an influential figure in those days and a fashion leader as well. Lastly, acceptance of working girl fashion depicted in American television shows. American working girls depicted on American TV shows were highly admired by young Korean women, so the fashion of American working girls became a major fad among young Korean women.

Electrochemical Properties of Polyaniline Electrodes Prepared by Chemical Synthesis and Electrodeposition: Revisited with High-Scan-Rate Behaviors

  • Nam, Ji Hyun;Woo, Cho Hyeon;Kim, Kwang Man;Ryu, Kwang Sun;Ko, Jang Myoun
    • Journal of Electrochemical Science and Technology
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    • v.3 no.2
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    • pp.80-84
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    • 2012
  • The polyaniline (PANI) electrodes are prepared by chemical synthesis and electrodeposition methods and their supercapacitive properties are characterized and compared by morphology observation, cyclic voltammetry as a function of scan rate, and impedance spectra analysis. In particular, the supercapacitive properties obtained in the range of higher potential scan rates (e.g., over $200mV\;s^{-1}$) are emphasized to be capable of utilizing adequately the high power capability of supercapacitor. As a result, the PANI electrode by the electrodeposition shows superior specific capacitance (max. $474F\;g^{-1}$ at $10mV\;s^{-1}$ and about $390F\;g^{-1}$ at $500mV\;s^{-1}$) than those by the chemical synthesis method. This is mainly due to highly porous structure obtained by the electrodeposition to yield higher specific surface area.

Performance evaluation of 80 GHz FMCW Radar for level measurement of cryogenic fluid

  • Mun, J.M.;Lee, J.H.;Lee, S.C.;Sim, K.D.;Kim, S.H.
    • Progress in Superconductivity and Cryogenics
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    • v.23 no.4
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    • pp.56-60
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    • 2021
  • The microwave Radar used for special purposes in the past is being applied in various areas due to the technological advancement and cost reduction, and is particularly applied to autonomous driving in the automobile field. The FMCW (Frequency Modulated Continuous Wave) Radar can acquire level information of liquid in vessel based on the beat frequency obtained by continuously transmitting and receiving signals by modulating the frequency over time. However, for cryogenic fluids with small impedance differences between liquid medium and gas medium, such as liquid nitrogen and liquid hydrogen, it is difficult to apply a typical Radar-based level meter. In this study, we develop an 80 GHz FMCW Radar for level measurement of cryogenic fluids with small impedance differences between media and analyze its characteristics. Here, because of the low intrinsic impedance difference, most of the transmitted signal passes through the liquid nitrogen interface and is reflected at the bottom of the vessel. To solve this problem, a radar measurement algorithm was designed to detect multiple targets and separate the distance signal to the bottom of the vessel in order to estimate the precise position on the liquid nitrogen interface. Thereafter, performance verification experiments were performed according to the liquid nitrogen level using the developed radar level meter.

Effect of Enzyme Supplementation on the Performance of Growing-Finishing Pigs Fed Barley-Based Diets Supplemented with Soybean Mealor Canola Meal

  • Thacker, P.A.
    • Asian-Australasian Journal of Animal Sciences
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    • v.14 no.7
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    • pp.1008-1013
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    • 2001
  • This experiment was conducted to determine the effects of enzyme supplementation on the performance of 80 growing-finishing pigs (26.2 kg) fed diets containing either soybean or canola meal. Barley-based diets formulated using either soybean meal or canola meal were fed with or without enzyme (Allzyme Vegpro, Alltech Biotechnology Centre). Eight castrates and twelve gilts were fed each diet. Digestibility of dry matter, crude protein and gross energy was 8.0 (p=0.0001), 7.9 (p=0.0005) and 7.9 (p=0.0003) percent lower for pigs fed diets containing canola meal compared with soybean meal. Enzyme supplementation had no effect on nutrient digestibility (p>0.05). There was a significant interaction between protein source and enzyme for all three nutrients. Over the entire experimental period (26.2 to 77.9 kg), pigs fed canola meal consumed 9.4% less feed (p=0.001), gained weight 20.4% slower (p=0.001) and had a 12.9% poorer feed conversion (p=0.001) than pigs fed soybean meal. Weight gain, feed intake and feed conversion were unaffected by enzyme addition (p>0.05). Castrates gained weight 11.4% faster (p=0.001), consumed 9.3% more feed (p=0.001) and had a 2.6% better feed conversion (p=0.026) than gilts. There was a significant interaction between protein source and sex of pig for feed conversion. Pigs fed diets based on canola meal had a significantly lower carcass value index (p=0.01), lower lean yield (p=0.007) and lower lean depth over the loin (p=0.001) than pigs fed diets based on soybean meal. Enzyme addition significantly increased lean depth over the loin (p=0.01). There was a significant interaction between protein source and enzyme for carcass value index (p=0.04), estimated lean yield (p=0.05) and fat depth over the loin (p=0.05). These results confirm previous studies which have demonstrated poorer pig performance when canola meal completely replaces soybean meal in diets fed to growing-finishing pigs. In addition, the results provide little justification for the inclusion of the Vegpro enzyme in diets fed to pigs of this weight range.

Clinical characteristics and treatment propensity in elderly patients aged over 80 years with colorectal cancer

  • Jung, Yun Hwa;Kim, Jae Young;Jang, Yu Na;Yoo, Sang Hoon;Kim, Gyo Hui;Lee, Kang Min;Lee, In Kyu;Chung, Su Mi;Woo, In Sook
    • The Korean journal of internal medicine
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    • v.33 no.6
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    • pp.1182-1193
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    • 2018
  • Background/Aims: Elderly patients (${\geq}80years$) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ${\geq}80years$ with CRC in clinical practice and the impact of anticancer treatment on overall survival (OS). Methods: Medical charts of 152 elderly patients (aged ${\geq}80years$) diagnosed with CRC between 1998 and 2012 were retrospectively reviewed. Patients' clinical characteristics, treatment modalities received, and clinical outcome were analyzed. Results: Their median age was 82 years (range, 80 to 98). Of 152 patients, 148 were assessable for the extent of the disease. Eighty-two of 98 patients with localized disease and 28 of 50 patients with metastatic disease had received surgery or chemotherapy or both. Surgery was performed in 79 of 98 patients with localized disease and 15 of 50 patients with metastatic disease. Chemotherapy was administered in only 24 of 50 patients with metastatic disease. Patients who received anticancer treatment according to disease extent showed significantly longer OS compared to untreated patients (localized disease, 76.2 months vs. 15.4 months, p = 0.000; metastatic disease, 9.9 months vs. 2.6 months, p = 0.001). Along with anticancer treatment, favorable performance status (PS) was associated with longer OS in multivariate analysis of clinical outcome. Conclusions: Elderly patients aged ${\geq}80years$ with CRC tended to receive less treatment for metastatic disease. Nevertheless, anticancer treatment in patients with favorable PS was effective in prolonging OS regardless of disease extent.

Sensitivity Analysis of the Optical System for UV-IR Space Telescope

  • Kim, Sanghyuk;Chang, Seunghyuk;Pak, Soojong;Jeong, Byeongjoon;Kim, Geon Hee;Hammar, Arvid
    • The Bulletin of The Korean Astronomical Society
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    • v.40 no.2
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    • pp.56.4-57
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    • 2015
  • We present the optical design and a sensitivity analysis for a wide field of view (FOV) instrument operating at UV and IR wavelengths. The ongoing investigation is performed in collaboration with Omnisys Instruments (Sweden) and focuses on a telluric-limb-viewing instrument that will fly in a low Earth orbit to study mesospheric wave structures over a wide range of horizontal scales in the altitude range 80 - 100 km. The instrument has six wavelength channels which consist of 4 channels of IR and 2 of UV. We are proposing an optical design based on three mirror aplanatic off-axis reflective system. The entrance pupil diameter and effective focal length are 45 mm and 270 mm, respectively. The FOV is $5.5^{\circ}{\times}1^{\circ}$ and the secondary mirror is set for stop. The optical specification is required to have an encircled energy of at least 80 % within a diameter of 21 um. We performed sensitivity analysis for the longest wavelength of 772 nm in consideration of the diffraction limit of system. The results show that tolerance limits for positions and angles of the mirrors are not very sensitive compared with typical error budgets of manufacturing and assembling process. The secondary mirror has the most sensitive tolerance for surface figure of 250 nm in root-mean-square.

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Effects of Levels of Crude Fiber on Growth Performances and Intestinal Carbohydrases of Domestic Goslings

  • Hsu, J.C.;Chen, L.I.;Yu, B.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.10
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    • pp.1450-1454
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    • 2000
  • This study was conducted to examine the effects of dietary crude fiber levels on the growth and intestinal carbohydrases of goslings. Thirty-two, 2 week old female White Roman goslings were divided into four groups of 4 goslings with 2 replicates. Diets were isocaloric and isonitrogenous, containing 40, 80, 120 or 160 g/kg crude fiber. At the end of the 4 weeks of the experimental period, all goslings were sacrificed and the carbohydrases activities were measured. Feed intake was significantly higher in the 120 and 160 g/kg crude fiber groups over that in the 40 and 80 g/kg groups (p<0.05). The average daily gosling weight gain significantly increased with increasing crude fiber levels from 40 to 120 g/kg. However, both the daily gain and feed conversion of the 160 g/kg crude fiber diet group decreased significantly. Amylase, maltase and ${\alpha}-glucosidase$ activities in the duodenum significantly decreased as the dietary crude fiber level increased. The maltase and ${\alpha}-glucosidase$ activities in the jejunum-ileum showed a similar trend with those in the duodenum. By increasing the levels of crude fiber, cellulase activity in the caecum content significantly increased. There was, however, an adverse effect on the amylase activity.