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복분자(Rubus coreanus) 추출물의 라디칼 소거활성 및 고지방 식이에 대한 흰쥐의 간 지질 개선 효과 (Antioxidant activity and hepatic lipids improvement effects of Rubus coreanus in high-fat diet-fed rats)

  • 이수정;송윤오;정민섭;장선희;원청길;송영민;조재현
    • 한국동물위생학회지
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    • 제38권2호
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    • pp.117-125
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    • 2015
  • This study was investigated the effects on the radical scavenging activities and hepatic lipid levels in rats fed a high-fat diet (HFD) by the 70% ethanolic extract from Rubus coreanus. The Rubus coreanus extract (RCE) was administered through the gastrointestinal tract at 150 mg/kg BW/day for 5 weeks (HFD+RCE). Total phenol content was 157.93 mg gallic acid/g in the RCE. Scavenging activities to DPPH, ABTS, an d hydroxyl radicals by RCE significantly increased in a does-dependent manner of $50{\sim}500{\mu}g/mL$ concentration. DPPH and ABTS radical scavenging activities were over the 70% in the $500{\mu}g/mL$ concentration. During the five weeks study, the food efficiency ratio was no significant differences between the HFD and HFD+RCE. Liver weight of HFD+RCE (3.75 g/100 g BW) was significantly decreased compared to those of the HFD. Hepatic triglyceride and total cholesterol levels of HFD+RCE were significantly lower compared to those of the HFD. The hepatic TBARS contents in the HFD+RCE was significantly decreased to the HFD, radical scavenging activity was markedly increased in HFD+RCE as normal group. In histological observation of liver tissues, the hepatocytes of HFD+RCE appeared the reduced aspects on the size and numbers of lipid droplets in cytoplasm compared to the HFD. Our results suggest that RCE could have antioxidant activities and hepatic hypolipidemic effects by its phenolic compounds.

부산 일부 지역의 어린이 급식시설에 대한 어린이급식관리지원센터의 위생.안전 관리 지원 효과 (Effects of Food Safety Management Support of Center for Children's Foodservice Management on Foodservice Facilities for Children in Busan Area)

  • 김성혜;오은영;한진숙
    • 동아시아식생활학회지
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    • 제24권2호
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    • pp.261-274
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    • 2014
  • The purpose of this study was to examine the effects of food safety management support in the Center for Children's Foodservice Management (CCFSM) on foodservice facilities for children in Busan area. We assessed the status of hygiene and safety practices of institutional and non-institutional foodservice on a quarterly basis by using an inspection checklist for food hygiene and safety developed by dieticians from February to December in 2013. The subjects were 103 children's foodservices, including 37 institutional and 66 non-institutional foodservices. Inspection checklist consisted of nine categories with 39 checklists; general characteristics, personal hygiene, ingredient control, menu planning, cooking processing control, serving management, washing, disinfection and storage control, and environment and safety management. The average score of each field (pre-supporting/post-supporting) in institutional foodservice was 0.56/0.92 for personal hygiene, 0.55/0.87 for ingredient control, 0.76/0.97 for menu planning, 0.53/0.89 for processing control, 0.27/0.67 for serving management, 0.47/0.91 for washing, disinfection and storage control, and 0.61/0.91 for environment management and 0.64/0.94 for safety management. In non-institutional foodservice, the average score of each field (pre-supporting/post-supporting) was 0.49/0.80 for personal hygiene, 0.52/0.75 for ingredient control, 0.78/0.97 for menu planning, 0.42/0.76 for processing control, 0.32/0.61 for serving management, 0.57/0.88 for washing, disinfection and storage control, and 0.46/0.82 for environment management and 0.73/0.88 for safety management. The average scores of all categories (pre-supporting/post-supporting) were 0.57/0.91 in institutional foodservice and 0.53/0.82 in non-institutional foodservice. The effects of management support in CCFSM on institutional foodservice were higher than those of non-institutional foodservice. Based on these results, we found that management support in CCFSM on foodservice facilities for children had a significantly positive effect on status of hygiene and safety practice regardless of foodservice facility size.

간헐적인 낮은강도, 짧은기간의 운동부하가 뒷다리 부유쥐의 Type II근육에 미치는 영향 (Effect of intermittent low-intensity, short duration exercise on Type IImuscle of suspended rats)

  • 최명애;지제근;김은희
    • 대한간호학회지
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    • 제25권2호
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    • pp.193-209
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    • 1995
  • The purpose of this study was to determine the effect of intermittent low - intensity, short duration exercise during hindlimb suspension on the mass, relative weight, myofibrillar protein content, cross-sectional area of Type I and Type II fibers and SDH activity in Type II(plantaris) muscle. To examine the effectiveness of intermittent low-intensity, short duration exercise on mass, myofibrillar protein content and fiber size, the hindlimbs of adult female Wistar rats were suspended(HS) and half of these rats walked on a treadmill for 45 min/day(9 min every 2h) at 5m /min and a 15$^{\circ}$grade (HS-EX). Plantaris wet weight was 19.67% significantly smaller(p<0.005) and relative plantaris weight was 6.25% smaller compared with those of control rats following seven days of hindlimb suspension. Plantaris wet weight and relative plantaris weight increased by 27.66%, 12.22% each through intermit-tent exercise during hindlimb suspension(p<0.005, p<0.05), moreover, plantaris wet weight and relative plantaris weight of the HS-EX rats were similar to those of control rats. Soleus wet weight and relative soleus weight decreased significantly by 31% and 22.0% in the HS rats(p<0.05). Soleus wet weight and relative soleus weight increased by 10.41%, 25.64% respectively through intermittent ex-ercise during hindlimb suspension, furthermore, soleus wet weight and relative weight of the HS-EX rats were closer to those of control rats. Myofibrillar protein content of plantaris and soleus decreased significantly by 51.49%, 59.65% each, following seven days of hindlimb suspension (p<0.005) Myofibrillar protein content of plantaris and soleus increased by 51.79%, 75.47% each with significance through intermittent exercise during hindlimb suspension(p<0.005). Myofibrillar protein content of plantaris and soleus in HS-EX rats was smaller than that of control rats. No change was observed in fiber type percentage following 1 week of hindlimb suspension or exercise during hindlimb suspension. The type I fiber cross-sectional area of both soleus and plantaris muscle was 18.72% and 41.07% lower in the HS than that of the controls (p<0.05, p<.001), that of both muscles was 6.60% and 29. 3% greater in the HS-EX than that of the HS rats. HS plus intermittent low- intensity short duration exercise resulted in Type I fiber cross-sectional area closer to the controls. Type II fiber cross-sectional area of both plantaris and soleus muscle was 22.45% and 22.58% sl nailer in the HS than in the controls, that of both muschles in the HS-EX was 14.10%, 5.78% greater than HS. Intermittent exercise during hindlimb suspension resulted in Type I, II fiber cross-sectional area closer to the control value. There was no change in SDH activity following 1week of hindlimb suspension or exercise during hindlimb suspension in the plantaris muscle. The results suggest that intermittent low intensity short duration exercise can ameliorate Type II muscular atrophy Induced by hindlimb suspension.

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5급와동의 복합레진 충전에 관한 유한요소법적 응력분석 (FINITE ELEMENT ANALYSIS OF STRESS DISTRIBUTION ACCORDING TO CAVITY DESIGN OF CLASS V COMPOSITE RESIN FILLING)

  • 엄정문;권혁춘;손호현;조병훈;임영일
    • Restorative Dentistry and Endodontics
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    • 제24권1호
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    • pp.67-75
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    • 1999
  • The use of composite restorative materials is established due to continuing improvements in the materials and restorative techniques. Composite resins are widely used for the restoration of cervical lesions because of esthetics, good physical properties and working time. There are several types of cavity design for class V composite resin filling, but inappropriate cavity form may affect bonding failure, microleakage and fracture during mastication. Cavity preparations for composite materials should be as conservative as possible. The extent of the preparation is usually determined by the size, shape, and location of the defect. The design of the cavity preparation to receive a composite restoration may vary depending on several factors. In this study, 5 types of class V cavity were prepared on each maxillary central incisor. The types are; 1) V-shape, 2) round(U) shape, 3) box form, 4) box form with incisal bevel and 5) box form with incisal bevel and grooves for axial line angles. After restoration, in order to observe the concentration of stress at bonding surfaces of teeth and restorations, developing a 2-dimensional finite element model of labiopalatal section in tooth, surrounding bone, periodontal ligament and gingiva, based on the measurements by Wheeler, loading force from direction of 45 degrees from lingual side near the incisal edge was applied. This study analysed Von Mises stress with SuperSap finite element analysis program(Algor Interactive System, Inc.). The results were as follows : 1. Stress concentration was prevalent at tooth-resin bonding surface of cervical side on each model. 2. In model 2 without line angle, stress was distributed evenly. 3. Preparing bevel eliminated stress concentration much or less at line angle. 4. Model with round-shape distributed stress concentration more evenly than box-type model with sharp line angle, therefore decreased possibility of fracture. 5. Adding grooves to line angles had no effect of decreasing stress concentration to the area.

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울릉도 주변 해역의 극미소플랑크톤 분포 특성 (Seasonal Variability of Picoplankton Around Ulneung Island)

  • 심정민;윤석현;황재동;진현국;이용화;김영숙;윤상철
    • 한국환경과학회지
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    • 제17권11호
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    • pp.1243-1253
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    • 2008
  • The seasonal variations of picoplankton including Prochlorococcus, Synechococcus and Picoeukayotes around Ulneung Island were investigated by flow cytometry in spring, summer and autumn in 2006. All groups of picoplankton showed clear seasonal patterns in population abundance. Among the group, Synechococcus showed the most prominent seasonal variation during the study period. The maximal abundance of Synechococcus occurred in summer and the lowest in autumn. The seasonal distribution of Prochlorococcus displayed the reverse tendency with that of Synechococcus. The abundance of Prochlorococcus ranged from $2.9{\times}10^3$ cells/ml in summer to $311{\times}10^3$ cells/ml in autumn. However, the seasonal distribution of Picoeukaryotes was shown to be relatively constant, and the maximal abundance was $81.5{\times}10^3$ cells/ml in summer. The highest abundance of Picoeukaryotes occurred in summer and the lowest in autumn and the seasonal distribution in abundance of Picoeukaryotes showed a similar trend with that of Synechococcus. The estimated total carbon biomass of picoplankton were ranged from $74.7\;mg\;C/m^2$ to $1,055.9\;mg\;C/m^2$. The highest total carbon biomass occurred in summer, but lowest occurred in autumn. The pattern of the contribution of three picoplankton to total autotrophic picoplankton carbon is different. The contribution of Synechococcus to total autotrophic picoplankton carbon is increased to 75%, but the contribution of Prochlorococcus dropped to 12% in summer. The contribution of Picoeukaryotes is ranged from 24% in summer to 72.5% in spring.

High Efficient Inductive Power Supply System Implemented for On Line Electric Vehicles

  • 허진;박은하;정구호;임춘택
    • 전력전자학회:학술대회논문집
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    • 전력전자학회 2009년도 정기총회 및 추계학술대회 논문집
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    • pp.105-110
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    • 2009
  • The On Line Electric Vehicles(OLEV) that can pick up inductive power from underground coils on driving with high efficiency have been developed this year, and is now proposed in this paper. The IPS(Inductive Power Supply) system consists of power supply inverters, power supply rails, pick up modules, and a regulator. There are 3 generations of IPS have been developed so far, and the $4^{th}$ generation IPS is being developed. The $1^{st}$ generation has been demonstrated this Feb. 27, which is equipped with mechanically auto tracking pick-up module with 1cm air gap, and showed 80% power efficiency. The $2^{nd}$ generation IPS applied to an 120kW (average)/240kW(peak) motor powered electric bus has 17cm air gap with 72% power efficiency. For the $2^{nd}$ generation IPS, the Power supply inverter has 440V, 3phase input and 200A @ 20kHz output. The test power supply rail of 240m long is segmented by 60m each, where newly developed core structure and power cable are constructed under the road covered with asphalt of 5cm thickness. The pick-up modules which consist of core, winding wire, and rectifiers are fixed to the bottom of the bus which can carry more than 40 passengers and can pick up max. 60kW. To remove parasitic component and to transfer maximum power between them resonant circuit topology is applied to the primary and secondary sides. The EMF level is below 62.5mG at 1.75m from the center of the road to meet the regulation. Several effective ways of reducing EMF levels have been developed. In addition, effective ways to solve problems related high frequency power cables buried in ground and it's proof from soil have been studied also. This development shows that the IPS system is capable of supplying enough power to the pick-up of OLEV and can reduce battery size, weight and cost, which means the IPS with OLEV is one of the best candidate for EV.

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한국 청년층 구순의 사진 계측학적 연구 (Photogrammetric Study of Lip in Young Population in Korean)

  • 김우섭;홍정수;김한구;김승홍
    • Archives of Plastic Surgery
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    • 제32권2호
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    • pp.155-160
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    • 2005
  • The aim of this study is to establish anatomical dimension of the lip in young population in Korean, using specially designed soft ware with photographic image. We measure 13 anatomical dimensions of lips in 2,229 young people. (917 male, 1312 female, Aged from 18-33 years. Average age 19.7). Statistical analysis of these measurements of large population could offer useful information in facial plastic surgery. The mean measurements are as follows 1. Lengths (male/female) Widths of philtrum: $1.11{\pm}0.19cm/1.02{\pm}0.21cm$ Heights of philtrum: $1.6{\pm}0.24cm/1.47{\pm}0.21cm$ Heights of cupid bow: $0.88{\pm}0.16cm/0.83{\pm}0.16cm$ Height of upper vermilion: $0.74{\pm}0.16cm/0.70{\pm}0.15cm$ Height of lower vermilion: $1.08{\pm}0.17cm/1.02{\pm}0.15cm$ Height of upper lip(Rt.): $1.24{\pm}0.2cm/1.23{\pm}0.2cm$ Height of upper lip(Lt.): $1.24{\pm}0.2cm/1.17{\pm}0.19cm$ Half horizontal length of lip: $2.2{\pm}0.26cm/2.11{\pm}0.2cm$ Horizontal length of lip: $4.41{\pm}0.4cm/4.25{\pm}0.36cm$ Height of lower face: $7.1{\pm}0.58cm/6.52{\pm}0.6cm$ 2. Angles Nasolabial angle: $97.77{\pm}11.97^{\circ}/95.5{\pm}11.34^{\circ}$ Mentolabial angle: $133.88{\pm}14.65^{\circ}/129.27{\pm}13.67^{\circ}$ Angle of Cupid's bow: $111.65{\pm}13.99^{\circ}/116.75{\pm}16.2^{\circ}$ Previous reported photogrammetric measurements was difficult to implement to surgical practice. Because these were printed photographies of the same size. Therefore, in this study, we can measure a lot of objects and items more conveniently and correctly by using proportional program on computer after taking a digital photograph. Consequently, proportional measurements with photogrammetry of lip could be useful and corrective substitute for anthropometrical measuring. These data could be useful reference for preoperative consultation, surgical planning and learning anatomical measurement of lips and adjacent structures.

노인급식 수혜자의 가정에서 배달 도시락 취급 및 섭취 실태와 가정배달 급식서비스에 대한 인식 (Clients' Handling and Consumption of Home-delivered Meals at Home and Their Perceptions on Home-Delivered Meal Services for Older Adults)

  • 박정연;이경은;이나영;곽동경
    • 대한지역사회영양학회지
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    • 제15권3호
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    • pp.379-392
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    • 2010
  • The purposes of this study were to investigate recipients' handling and consumption of home-delivered meals at home and to assess their perceptions on home-delivered meal services for older adults. A total of 312 elderly people who received home-delivered foodservice were surveyed using an individual interview technique. A statistical data analysis was completed using SPSS (ver. 14.0). It was found that 90.2% (n = 166) of the lunch box recipients received services for six days per week, and 76.6% (n = 95) of the side-dish recipients got services once per week. More than half of the clients reported that they cooked meals by themselves on days when meals were not delivered. The two hundred thirty-two (75.3%) ate their meals as soon as they were delivered. It was found that 66.8% of the lunch box recipients and 7.3% of the side-dish recipients left delivered meals on the counter (at room temperatures) before eating. Only 11.4% of the lunch box recipients and 48.4% of the side-dish recipients kept delivered meals in the refrigerator before eating. Less than half of the lunch box recipients consumed all foods they were served at once. The reasons the recipients did not eat their all meals delivered at once were "saving for next meals" and "big portion size" Of those clients who left delivered meals, 19% of the lunch box recipients and 9.7% of the side-dish recipients ate leftovers without reheating. An average score of quality of delivered meal services was 3.5 out of 5 points. The results suggest that the clients of the home-delivered meal service should be provided information on proper handling and consumption practices with delivered meals at home. The findings of the study will be used to develop nutrition and food safety management guidelines for senior foodservice.

Korean Red Ginseng alleviates dehydroepiandrosterone-induced polycystic ovarian syndrome in rats via its antiinflammatory and antioxidant activities

  • Choi, Jong Hee;Jang, Minhee;Kim, Eun-Jeong;Lee, Min Jung;Park, Kyoung Sun;Kim, Seung-Hyun;In, Jun-Gyo;Kwak, Yi-Seong;Park, Dae-Hun;Cho, Seung-Sik;Nah, Seung-Yeol;Cho, Ik-Hyun;Bae, Chun-Sik
    • Journal of Ginseng Research
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    • 제44권6호
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    • pp.790-798
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    • 2020
  • Background: Beneficial effects of Korean Red Ginseng (KRG) on polycystic ovarian syndrome (PCOS) remains unclear. Methods: We examined whether pretreatment (daily from 2 hours before PCOS induction) with KRG extract in water (KRGE; 75 and 150 mg/kg/day, p.o.) could exert a favorable effect in a dehydroepian-drosterone (DHEA)-induced PCOS rat model. Results: Pretreatment with KRGE significantly inhibited the elevation of body and ovary weights, the increase in number and size of ovarian cysts, and the elevation of serum testosterone and estradiol levels induced by DHEA. Pretreatment with KRGE also inhibited macrophage infiltration and enhanced mRNA expression levels of chemokines [interleukin (IL)-8, monocyte chemoattractant protein-1), proinflammatory cytokines (IL-1β, IL-6), and inducible nitric oxide synthase in ovaries induced by DHEA. It also prevented the reduction in mRNA expression of growth factors (epidermal growth factor, transforming growth factor-beta (EGF, TGF-β)) related to inhibition of the nuclear factor kappa-light-chain-enhancer of activated B cell pathway and stimulation of the nuclear factor erythroid-derived 2-related factor 2 pathway. Interestingly, KRGE or representative ginsenosides (Rb1, Rg1, and Rg3(s)) inhibited the activity of inflammatory enzymes cyclooxygenase-2 and iNOS, cytosolic p-IκB, and nuclear p-nuclear factor kappa-light-chain-enhancer of activated B in lipopolysaccharide-induced RAW264.7 cells, whereas they increased nuclear factor erythroid-derived 2-related factor 2 nuclear translocation. Conclusion: These results provide that KRGE could prevent DHEA-induced PCOS via antiinflammatory and antioxidant activities. Thus, KRGE may be used in preventive and therapeutic strategies for PCOS-like symptoms.

멸종위기종 수리부엉이의 형태학적 및 혈액학적 분석 (Morphological and hematological analysis of and angered Eurasian eagle owl (Bubo bubo kiautschensis))

  • 정배동;박인철;김정남;김현철;정기수;김종택
    • 한국동물위생학회지
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    • 제32권4호
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    • pp.391-397
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    • 2009
  • Eurasian eagle owl (Bubo bubo kiautschensis) is a natural monument (No. 324) and is also classified as an endangered wildlife grade II the Ministry of Environment of Korea. Eurasian eagle owl is threatened by the human being. But the efficient rescue and treatment for Eurasian eagle owl are still problematic, due to lack of basic data. In this study, to obtain basic resources for establishing more efficient rescue system, we held a physical examination and measured size physical part. In addition, we analyzed blood sample and feces samples and autopsy. We conduct the physical examination with measuring tapes and scales for 16 live features and 11 dead features. After inhalation anesthesia take the blood samples from wing vein. Blood samples are analyzed in hematologic and chemistric methods. We collected the feces through individual floor of cages from 12 live features and conducted the feces analysis. Autopsy was conducted for 11 dead samples. In physical examination, the mean body weight and total length of live features was 2.26${\pm}$0.35kg, 61${\pm}$2.38cm, the mean body weight and total length of dead features was 1.57${\pm}$0.51kg, 59.31${\pm}$3.51cm. Mean PCV was 46.57${\pm}$4.97%, while mean TPP was 3.49${\pm}$0.57g/dL. In feces sample analysis, 9 of 12 owls(75%) were infested by gastrointestinal helminths. The infection rates were: Trematoda (41.7%), Capilaria sp.(66.7%), acanthocephalans (25%). In autopsy, we confirmed 11 features were infested by duplicated infection of more than 2 helminths. Result of this study will be used for establishing reference range for physical features, blood analysis in Eurasian eagle owl. Therefore, to obtain basic resources for establishing more efficient rescue system, we have to make long-term conservation plans for Eurasian eagle owl.