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Miller Fisher syndrome in a patient with pulmonary tuberculosis

  • Park, Jae Young;Jung, Hoe Jong;Bae, Heewon;Han, Jeong-Ho;Kang, Min Ju
    • Annals of Clinical Neurophysiology
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    • v.22 no.2
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    • pp.117-120
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    • 2020
  • Miller Fisher syndrome (MFS) is characterized by the acute ophthalmoparesis, ataxia and areflexia. We describe the case of 70-year-old man with cardinal symptom of MFS and active pulmonary tuberculosis (Tb). A thorough evaluation led to the diagnosis of MFS and treatment with intravenous immunoglobulin (IVIg) was started. The complete resolution of ophthalmoparesis and ataxia was observed from the fourth day of IVIg treatment. This is the first report to describe a case of MFS that developed in patient pulmonary tuberculosis.

Isolated facial diplegia variant of Guillain-Barré syndrome with anti-GM1 IgG antibody

  • Jung, Jin Ho;Lee, Sukyoon;Seo, Jung Hwa;Bae, Jong Seok;Shin, Kyong Jin;Kim, Jong Kuk;Yoon, Byeol-A;Oh, Seong-il
    • Annals of Clinical Neurophysiology
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    • v.24 no.1
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    • pp.17-20
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    • 2022
  • Facial diplegia (FD) rarely occurs as a regional Guillain-Barré syndrome (GBS) variant. A 70-year-old male presented with bifacial weakness that had started on the left side and extended to the right after several days. He was then treated using steroids and gradually improved. Serum antiganglioside antibody testing revealed positivity for anti-GM1 IgG antibodies. FD can be idiopathic, but it is an uncommon GBS variant. The ganglioside antibody test may increase the possibility of diagnosing isolated FD.

Potential risks of nerve conduction studies and needle electromyography

  • Yoon, Byung-Nam;Ahn, Suk-Won;Kim, Jee-Eun;Seok, Jin Myoung;Kim, Kwang-Kuk;Kwon, Ki-Han;Park, Kee Duk;Suh, Bum Chun;Lim, Young Min;Korean Society of Clinical Neurophysiology Education Committee
    • Annals of Clinical Neurophysiology
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    • v.20 no.2
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    • pp.66-70
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    • 2018
  • Electrodiagnostic studies such as nerve conduction studies (NCS) and needle electromyography (EMG) provide important and complementary information for evaluating patients with suspected neuromuscular disorders. NCS and needle EMG are reasonably safe diagnostic investigations and are generally associated with only mild transient discomfort when performed by experienced physicians. However, there is the risk of complications in some patients, because NCS involve the administration of electric current and EMG involves inserting a needle percutaneously into muscle tissue. This article reviews the potential risks of NCS and needle EMG.

Simultaneous analysis of sugars by HPLC (HPLC를 이용한 당류의 동시분석법)

  • 허부홍;서형석;김성문;김영진;조종후
    • Korean Journal of Veterinary Service
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    • v.23 no.2
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    • pp.137-142
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    • 2000
  • In order to develop a good separation and simultaneous analysis of different sugar in an artificial mixed sugar solution, we analyzed 10 sugar components in an artificial mixed sugar solution composed of fructose, glucose, mannitol, sucrose, maltose, lactose, xylose, xylitol erythritol, and trehalose with using HPLC-ELSD or HPLC-RI. Separation and quantification by HPLC-ELSD was superior to those by HPLC-RI and detection sensitivity by HPLC-ELSD was higher then that by HPLC-RI as micorgram($\mu\textrm{g}$) level. 1. The units of minimal detectable limits were showed $\mu\textrm{g}$/$m\ell$ and ng/$m\ell$ by the HPLC-RI and HPLC-ELSD, respectively. 2. The condition of ELSD was drift tube temperature $82^{\circ}C$, $N_2$ gas flow rate 2.10 SLPM, and colum oven temperature $30^{\circ}C$, respectively. Isolation and recovery rates of single sugar from the multiple sugar solution was higher at the condition (time: flow rate: D.W.:ACN MeOH, min : $m\ell$/min:v:v:v) of linear gradient elution of mobile phase as 0 : 1.00 : 15 : 85 : 0.1 : 1.00 : 6 : 90 : 4, 17 : 1.00 : 10 : 70 : 20, 28 : 1.00 : 15 : 85 : 0 an 35 : 1.00 : 15 : 85 : 0, in order.

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Residue by elapsed time of non-enzymatic antioxidants in dentifrice (세치제에 함유된 비효소계 항산화제의 경시변화에 따른 잔류량)

  • Park, Jung-Eun;Park, Yong-Duk;Hong, Tae-Gi;Jang, Jong-Hwa
    • Journal of Korean society of Dental Hygiene
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    • v.16 no.5
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    • pp.783-790
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    • 2016
  • Objectives: The purpose of this study is to evaluate the non-enzymatic antioxidants stabilities in dentifrices by ascorbic acid and tocopherol according to the chemical condition. Methods: For the analysis of two antioxidants, HPLC UV detector system was used. HPLC was performed using sodium sulfate, acetonitrile(ACN), methanol(MeOH) and measuring absorbance at 240-295 nm. To confirm general pH reaction of two compounds, buffer solution was prepared for the analysis. The dentifrice was titrated by pH so as to examine the change of elapsed time in dentifrice. Linearity of calibration curve of two antioxidants was measured. Results: Each compound showed good linearity at optimized wavelength as well as showing good precision. General pH reaction of two antioxidants was examined. Ascorbic acid showed the highest residue(63.23%) at pH 10 and the lowest residue(2.77%) at pH 4. Tocopherol showed the highest residue(55.70%) at pH 7 and the lowest residue(3.31%) at pH 4. As a result of changing elapsed time of antioxidants in dentifrice by pH, components were remained stably at low temperature($39.2^{\circ}F$) and pH 7. Conclusions: It is necessary to keep dentifrice including ascorbic acid and tocopherol, and non-enzymatic antioxidants at pH 7 and low temperature for improving chemical stability.

Technological Progress and Issues on the Recycling of Urban Mine Resources - Comparison of Korea with Japan - (도시광산(都市鑛山) 재자원화기술(再資源化技術)의 진보(進步)와 과제(課題) - 일본(日本)과 한국(韓國)의 비교(比較) -)

  • Oh, Jae-Hyun;Kim, Joon-Soo;Moon, Suk-Min;Min, Ji-Won
    • Resources Recycling
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    • v.21 no.2
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    • pp.17-33
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    • 2012
  • In order to review the recent technological progress and issues on the urban mine resources recycling in Japan and Korea, recycling process of the ELV(End of Life Vehicles) and E-waste(WEEE) were studied. Although technological level for processing of the ELV and E-waste is almost similar in both countries, the treatment of hazadous materials of ELV such as freon, air bag and ASR is unsufficient in Korea. In the E-waste recycling, the technological level is deeply different according to the enterprise size in Korea. Finally, the big R&D project on recycling of urban mine resources sponsored by government in both countries were discussed.

Optimization of Analytical Conditions for the Quantification of Explosive Compounds in Soil using HPLC (HPLC에 의한 토양내 화약물질 정량분석조건 최적화)

  • Cho, Jung-Hyun;Bae, Bum-Han;Kim, Kye-Hoon
    • Journal of Soil and Groundwater Environment
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    • v.14 no.1
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    • pp.51-60
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    • 2009
  • A series of experiments was performed to develop an optimized analytical procedure for the analysis of explosives in soil by HPLC with soil samples collected at two live-fire military shooting ranges. The minimum amount of soil to be collected, Wmin, for the analysis of explosive compounds was 125g, based on the segregation and homogeneity constants that account for soil heterogeneity and non-homogeneous distribution of target explosive compounds. The optimization of extraction and HPLC analytical conditions were also studied based on analytes CV values. The most effective soil/ extractant ratio was estimated to be 10g-pretreated soil/20 mL acetonitrile as extractant. The optimized HPLC elution conditions for the separation of US EPA designated 14 explosive compounds, were column temperature 30${\circ}C$, eluents ratio of isopropanol: acetonitrile: water = 18 : 12: 70, and flow rate of 0.8 mUmin at 230 nm. However, UV wavelength 254 nm was better for the analysis of NB, 2,4-DNT, 2NT, 4NT, and 3NT.