• 제목/요약/키워드: 6PPD

검색결과 115건 처리시간 0.03초

산후 우울 수준과 분만전후 관련 요인에 관한 연구 (Postpartum Depressive Score and Related Factors Pre- and Post-delivery)

  • 이선옥;여정희;안숙희;이현숙;양현주;한미정
    • 여성건강간호학회지
    • /
    • 제16권1호
    • /
    • pp.29-36
    • /
    • 2010
  • Purpose: This study aimed to identify the scores of postpartum depression(PPD) on the first day, 1st week, and 6th week after the delivery and to explore their related factors before and after delivery in postpartum women. Methods: With a survey design, 293 postpartum women were recruited from a postpartum unit, Ilsin Christian hospital in Pusan via convenience sampling and were followed at 1st week and 6th week in the outpatient clinic. Results: Results showed that the scores of PPD(EPDS score) were low at postpartum 1st day, 1st week and 6th week but prevalence of PPD(EPDS ${\geq}13$)was 3.1%at 1st day, 8.2%at 1st week and 7.5%at 6th week, respectively. The pre-delivery factors were experience of depression, and the post-delivery factors were baby's sex(1st day), no caregiver for baby(1st week), and no help and concern for taking care of baby from husband and family(1st day and 6th week). The greater satisfaction with becoming a mother and her life, and greater maternal attachment were related to lower level of PPD at the three time points. Conclusion: Regular screening for postpartum depression and supportive and informative education is needed for postpartum women visiting the outpatient clinic for follow-up.

Determination of Ginsenosides Content in Korean Ginseng Seeds and Roots by High Performance Liquid Chromatography

  • Hu, Jiang Ning;Lee, Jeung-Hee;Shin, Jung-Ah;Choi, Jae-Eul;Lee, Ki-Teak
    • Food Science and Biotechnology
    • /
    • 제17권2호
    • /
    • pp.430-433
    • /
    • 2008
  • A high performance liquid chromatography (HPLC) method has been successfully developed to identify and quantify major ginsenosides in Korean ginseng seeds and roots. Using gradient elution of acetonitrile and water without buffer, the 6 major ginsenosides ($Rb_1,\;Rb_2$, Rc, Rd, Re, and $Rg_1$) were identified. Compared with ginseng roots, the amount of ginsenoside Re and Rd in ginseng seeds were significantly higher than those in ginseng roots (p<0.05). In ginseng seeds, the content of protopanaxtriol (PPT) was higher than that of protopanaxdiol (PPD) and the ratio of PPT and PPD was approximately 2.2 : 1. However, the content of PPT was lower than that of PPD in ginseng roots. It should be mentioned that both content of PPT and PPD in ginseng seeds were much higher than those in ginseng roots.

Assembly of Laccase over Platinum Oxide Surface and Application as an Amperometric Biosensor

  • Quan, De;Kim, You-sung;Yoon, Kyung-Byung;Shin, Woon-sup
    • Bulletin of the Korean Chemical Society
    • /
    • 제23권3호
    • /
    • pp.385-390
    • /
    • 2002
  • Laccase could be successfully assembled on an amine-derivatized platinum electrode by glutaraldehyde coupling. The enzyme layer formed on the surface does not communicate electron directly with the electrode, but the enzymatic activity of the surf ace could be followed by electrochemical detection of enzymatically oxidized products. The well-known laccase substrates, ABTS (2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid)) and PPD (p-phenylenediamine) were used. ABTS can be detected down to 0.5 ${\mu}M$ with linear response up to 15 ${\mu}M$ and current sensitivity of 75 nA/ ${\mu}M.$ PPD showed better response with detection limit of 0.05 ${\mu}M$, linear response up to 20 ${\mu}M$, and current sensitivity of 340 nA/ ${\mu}M$ with the same electrode. The sensor responses fit well to the Michaelis-Menten equation and apparent $K_M$ values are 0.16 mM for ABTS and 0.055 mM for PPD, which show the enzymatic reaction is the rate-determining step. The laccase electrode we developed is very stable and more than 80% of initial activity was still maintained after 2 months of uses.

Leukocyte adherence inhibition test를 이용한 Mycobacterium 속균(屬菌) 감작(感作)기니픽의 세포면역반응(細胞免疫反應)의 특이성(特異性) (Specificity of cell-mediated immunity in guinea pigs sensitized with Mycobacterium spp using the leukocyte adherence inhibition test)

  • 박성국;전무형;이헌준;민원기;윤용덕
    • 대한수의학회지
    • /
    • 제29권3호
    • /
    • pp.283-289
    • /
    • 1989
  • In order to measure in vitro cell mediated immunity in the guinea pigs sensitized with the killed bacilli of Mycobacterium bovis ($AN_5$), M avium (serotype 2), M tuberculosis and M intracellulare (serotype 8), leukocyte adherence inhibition (LAI) test was established using the antigens of purified protein derivatives (PPD) tuberculin. By using LAI test, specificity of cell-mediated immune responses of the guinea pigs inoculated with various Mycobacterium spp was investigated, and comparison between values of LAI and skin test was also made to evaluate the specificity of the newly designed test. The results obtained throughout the experiments were summarized as follows; 1. The optimal concentration of PPD antigens for LAI test was 1 to 2mg per ml of medium. 2. When the leukocytes of guinea pigs sensitized with both M bovis($AN_5$) and M avium (serotype 2) for 2 to 8 weeks were incubated with homologous or heterologous PPD antigens, mean values of LAI test were $61.2{\pm}11.2$ and $65.6{\pm}5.1%$ in homologous PPD antigens respectively, while $30.0{\pm}3.7$ and $32.8{\pm}5.7%$ in heteNlogous PPD antigens, showing the prominently high value of LAI in the homologous syst,em (p<0.01). 3. When the leukocytes of guinea pigs sensitized with both M tuberculosis and M intracellulare (serotype 8) for 2 to 8 weeks were incubated with homologous and heterologous PPD antigens, mean values of LAI test were $67.9{\pm}2.9$ and $66.9{\pm}5.0%$ in homologous PPD antigens, while $27.4{\pm}7.4$ and $24.4{\pm}7.1%$ in heterologous PPD antigens, showing the prominently high value of LAI in the homologous system (p<0.01). 4. Comparing with the specificity of LAI and skin tests on the basis of the value obtained from the homologous system, deviation of reaction was revealed to be 49.5 to 100.2 in LAI test, and -15.9 to 52.0 in skin test.

  • PDF

芳香族디아민 및 아미노페놀-포름알데히드系 樹脂에 관한 硏究 (第2報) (Studies on Aromatic Diamine and Aminophenol-Formaldehyde Type Synthetic Resins (II))

  • 최규석
    • 대한화학회지
    • /
    • 제18권5호
    • /
    • pp.381-388
    • /
    • 1974
  • p-Phenylenediamine(PPD) 및 m-aminophenol(MAP)를 몰비를 달리하면서, -5∼0$^{\circ}$, $N_2$ 기류중에서 일정량의 포르말린(이때 포름알데히드의 량은 PPD와 MAP 전량에 대하여 2배몰에 해당하는 량으로 고정)과 반응시키면 약간의 발열과 함께 급격히 부가축합이 진행되어 난용성인 갈색 내지 등색의 중합체를 생성한다. PPD:MAP의 몰비가 1:3, 1:2, 1:1의 것들을 180∼220에서 몰비가 2:1, 3:1의 것들을 250∼270$^{\circ}$에서 각각 암색으로 색변화를 이르킬 따름이며, 이 중합체들은 모두 300$^{\circ}$까지 용융하지 않는다. 이들 중합체의 메틸렌블루에 대한 흡착력은 N2 기류중에서 중합시킨것을 묽은(7%) 수산화나트륨으로 처리하였을때 현저히 흡착력이 증가되어 PPD-MAP-F(F;포름알데히드)의 몰비가 1:3:8 일때 수지 1g당 80mg의 메틸렌블루를 흡착하며, 브롬페놀블루에대한 흡착력은 PPD-MAP-F의 몰비가 2:1:6일때가 최고이며, 수지 1g당 250mg의 브롬페놀블루를 흡착한다. TGA에 의한 내열성실험에서는 PPD-MAP-F의 몰비가 1:3:8인 경우 가장 좋은 결과를 나타냈으며, $N_2$ 기류중 매분 2$^{\circ}$로 가열하였을때 900$^{\circ}$에서 45%의 중량손실을 나타내었다.

  • PDF

새 국립중앙박물관 로튠다에서의 열환경 분석 (Analysis on Thermal Environment in the Rotunda of New National Museum of Korea)

  • 이승철;조영진;김두성;이재헌;김홍범
    • 설비공학논문집
    • /
    • 제15권1호
    • /
    • pp.32-39
    • /
    • 2003
  • Thermal comfort in the Rotunda which is high wide visiting space of the new national museum of Korea has been numerically investigated in this paper. To evaluate thor-mal comfort of the Rotunda, well-known indices, PMV and PPD were introduced. The results of present investigation show that thermal comfort is satisfied at the breathing zone of the visiting space. However a thermal stratification with $9^{\circ}C$ of temperature difference occurs along the height of the Rotunda which makes the thermal environment worse. For example, the PPD value reaches up to 50% in the 6th floor connection passage. Consequently, additional HVAC design factors should be considered in order to reduce the large thermal stratification.

비흡수성 차폐막을 이용한 치조골재생술의 임상적 효과 (A Retrospective Study of the Clinical Outcome of Guided Tissue Regeneration in infrabony defects)

  • 김정혜
    • Journal of Periodontal and Implant Science
    • /
    • 제27권3호
    • /
    • pp.525-532
    • /
    • 1997
  • The purpose of this study was to evaluate the extent and predictability of periodontal regeneration with barrier membranes in deep infrabony defects. 25 patients(40% smokers) were included in this study. Fourty-one deep infrabony defects treated with membranes(PPD>6mm) were evaluated 1 year postoperatively following a plaque control regimen. Probing pocket depth(PPD), gingival recession(REC), and probing attachment level(PAL) were evaluated at baseline and postoperative 1 year. Plaque score at baseline was 16.2 and plaque score at 1 year was 9.9 A PAL gain of $4.1{\pm}2.5mm$ along with a PPD reduction of $5.0{\pm}2.3mm$ were observed. A PAL gain of $4.1{\pm}2.5mm$ was observed at the smoking group and a PAL gain of $4.0{\pm}2.5mm$ was observed at the non-smoking sroup. It was concluded that periodontal regeneration with membrane represented the predictable and effective treatment modality in the deep infrabony defects.

  • PDF

통나무집의 동절기 실내 온열감 평가에 관한 연구 (A Study on the Thermal Sensation Vote of the Log House in Winter Season)

  • 민병철;전지현;신용규;강상우;국찬
    • 한국주거학회:학술대회논문집
    • /
    • 한국주거학회 2006년도 추계학술발표대회 논문집
    • /
    • pp.297-300
    • /
    • 2006
  • Various buildings constructed by environmentally friendly resources are being built in KOREA. Especially the building made by the wood, which has environmental characteristics that the reinforced concrete and brick doesn't have, are acknowledged with its superiority. Then, studies on indoor thermal control capability of the wooden building and influence of its indoor environment to sensory environment of occupants are not enough proceed. Thus, there were proceeded 24 hours measurements for indoor and outdoor thermal environmental elements of Log Cabins and the hourly subjective tests to evaluate indoor amenity of occupants in this study. The results of the study are following: 1) Upon evaluation on thermal environment elements, indoor and outdoor dry bulb temp were 22.0$^{\circ}C$ and -2.9$^{\circ}C$, and Indoor and outdoor average relative humidity were 25.8%and 52.7%. Differences of indoor and outdoor temperature and humidity were 24.9$^{\circ}C$ and 26.9%. 2) Upon contrastive analysis between the results of subjective tests, warm and cold sensation vote, and PMV (Predicted Mean Vote) and PPD (Predicted Percent Dissatisfaction), values of subjective tests W.9

  • PDF

비우식성 치경부병소를 가진 구치부 치아의 교합 및 치주상태에 관한 연구 (Occlusal and Periodontal Status of Teeth with Non-carious Cervical lesions)

  • 손민욱;서성찬;정동근;이은숙;김형섭
    • Journal of Periodontal and Implant Science
    • /
    • 제34권3호
    • /
    • pp.647-657
    • /
    • 2004
  • A non-carious cervical lesion(NCCL) is the loss of tooth structure at the cementoenamel junction level that is unrelated to dental caries. This study was to evaluate the occlusal and periodontal status of teeth with non-carious cervical lesions. We evaluated 105 teeth with non-carious cervical lesions in 35 subjects aged 38-75 years and characterized them based on the shape and dimension, plaque retention, bleeding on probing(BOP), probing pocket depth(PPD), occlusal status, brushing type, hypersensitivity and wear facet. The results of this study were as follows 1. No significant association was observed between cervical lesions and occlusal contact in lateral excursions. 2. No significant difference occurred in plaque retention, PPD, BOP between teeth with and without cervical lesions. 3. Test teeth had a significantly higher percentage of hypersensitivity and occlusal wear facet than teeth without cervical lesions. 4. Wedge shaped lesions had a significantly higher percentage of plaque than saucer shaped lesions. 5. Teeth with plaque were found to have significantly deeper PPD than teeth without plaque retention in cervical regions. 6. Teeth with occlusal contacts were found to have significantly deeper PPD than teeth without occlusal contacts. 7. No significant association was observed between cervical lesions and PPD independent of plaque retention and occlusal contacts Although more knowledge is necessary, our results suggest that occlusal contact and bacterial plaque may influence on periodontal tissue, but NCCL is not directly associated with periodontal health

Protopanaxadiol modulates LPS-induced inflammatory activity in murine macrophage RAW264.7 cells

  • Lee, Whi-Min;Kim, Sung-Dae;Kim, Kil-Soo;Song, Yong-Bum;Kwak, Yi-Seong;Cho, Jae-Youl;Park, Hwa-Jin;Oh, Jae-Wook;Rhee, Man-Hee
    • Journal of Ginseng Research
    • /
    • 제30권4호
    • /
    • pp.181-187
    • /
    • 2006
  • Protopanaxadiol (PPD) is a mixture of protopanaxadiol type saponins with a dammarane skeleton, from Korean red ginseng (Panax ginseng C.A. Meyer; Araliaceae). Korean ginseng is well-known herb to treat almost all kinds of diseases in Oriental medicine. This herb was particularly prescribed for treatment various inflammatory diseases, including rheumatoid arthritis, atherosclerosis, and diabetes mellitus, for centuries. To understand the efficacy of ginseng against inflammatory diseases, we aimed to show anti-inflammatory activities of the PPD in murine macrophage cell line, RAW264.7 cells using nitric oxide (NO) production assay and the expressions of pro-inflammatory cytokines, such as tumor necrosis $factor-{\alpha}$ ($TNF-{\alpha}$), interleukin-$1{\beta}$ (IL-$1{\beta}$), and IL-6, and monocyte chemotactic protein-1 (MCP-1). We found that PPD saponin significantly blocked LPS ($1{\mu}g/ml$)-induced NO production in a dose-dependent manner. In addition, PPD abrogated the expressions of LPS-induced pro-inflammatory cytokines, such as IL-$1{\beta}$ and MCP-1. Moreover, cyclooxygenase (COX)-2, a critical enzyme to produce prostaglandin E2 (PGE2), was significantly inhibited by PPD in LPS-activated RAW264.7 cells. Taken together, these results suggested that anti-inflammatory efficacy of Korean red ginseng on inflammatory diseases is, at least, due to the NO inhibitory activity and the inhibition of the expressional level of inflammatory cytokines and/or mediators.