• BMB Reports
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• v.51 no.1
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• pp.33-38
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• 2018

Sterol regulatory element-binding protein-1c (SREBP1c) plays an important role in triglyceride (TG) homeostasis. Although our previous study showed that hepatitis C virus core-binding protein 6 (HCBP6) regulates SREBP1c expression to maintain intracellular TG homeostasis, the mechanism underlying this regulation is unclear. In the present study, we found that HCBP6 increased intracellular TG levels by upregulating SREBP1c expression. HCBP6 increased SREBP1c transcription by directly binding to the SREBP1c promoter (at the -139- to +359-bp region). Moreover, we observed that HCBP6 interacted with $C/EBP{\beta}-binding$ site in the SREBP1c promoter both in vitro and in vivo. These results indicate that HCBP6 upregulates human SREBP1c expression by binding to the $C/EBP{\beta}-binding$ site in the SREBP1c promoter.

• Journal of Preventive Medicine and Public Health
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• v.42 no.1
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• pp.42-48
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• 2009

Objectives : This study was conducted to examine the factors implicated when people start smoking again after a 6 month cessation, and was carried out at the smoking cessation clinic of a public health center. Methods : The study subjects were 191 males who had attended the smoking cessation clinic of a public health center for 6 months in an attempt to quit smoking. Data was collected, by phone interview, regarding individual smoking habits, if any, over the 6 month study period. The factors which may have caused an individual to smoke again were examined. This study employed a health belief model as it theoretical basis. Results : Following a 6 month cessation, 24.1% of the study group began to smoke again during the 6 month test period. In a simple analysis, the factors related to individuals relapsing and smoking again included barriers of stress reduction, body weight gain and induction of smoking by surroundings among perceived barriers factor of our health belief model(p<0.05). In multiple logistic regression analysis for relapsed smoking, significant factors included barriers of stress reduction and induction of smoking by surroundings(p<0.05). The most important reason of for an individual to relapse into smoking was stress(60.9%) and the most likely place for a relapse to occur was a drinking establishment(39.1%). Conclusions : Our results indicate that both regular consultations and a follow-up management program are important considerations in a public health center program geared towards maintaining smoking cessation.

• Journal of Korean Society for Quality Management
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• v.31 no.4
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• pp.81-94
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• 2003

Six sigma is a management innovation strategy which improves all managerial processes in an integrated manner, Six sigma can be applied to every aspect of managerial functions such as marketing, engineering, purchasing, accounting, and so on. Six sigma is trying to solve quality problems from the customer's viewpoint in the scientific manner, thus maximizing profits through the elimination of quality costs. This paper is presented to verify empirically the successful factors of implementing six sigma through the survey of black­belts of Korean firms. The blue­chip companies in Korea and across the world have already adopted Six Sigma, and it is becoming an integral part of the corporate culture of these companies. In conclusion, the most important factors to the success of six sigma are found to be the leadership of top management, and the compensation/ incentive system. The analysis also shows that the important factors are different in terms of both the process type and implementing stage.

• Korean Journal of Pharmacognosy
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• v.47 no.3
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• pp.217-221
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• 2016

Endophytic fungi have yielded a variety of secondary metabolites so far. In the course of the project to find bioactive secondary metabolites from cultures of endophytic fungi, an isolate of Arthrinium phaeospermum (JS 0567) was selected for chemical investigation. A large scale culture of this strain in rice media was extracted with an organic solvent and the extract was subjected to a serious of chromatography, which led to six metabolites. Their chemical structures were elucidated as 2,3,6,8-tetrahydroxy-1-methylxanthone(1), 2,3,4,6,8-pentahydroxy-1-methylxanthone(2), 3,4,6,8-tetrahydroxy-1-methylxanthone(3), 3,6,8-trihydroxy-1-methylxanthone(4), 2,4,2',4',6'-pentahydroxy-6-methylbenzophenone(5), and 5,7-di hydroxy-3-methylphthalide(6) on the basis of spectroscopic data. To the best of our knowledge, this is the first study on the secondary metabolites from Arthrinium phaeospermum.

• Proceedings of the KIEE Conference
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• 2004.11a
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• pp.129-132
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• 2004

This paper presents an experimental study on the prebreakdown characteristics in $SF_6/N_2$ mixtures under non-uniform electric fields when subjected to the positive and negative lightning impulse voltages. $SF_6/N_2$ mixtures have a merit of an environmental aspect and cost reduction, and safty aspects. In order to analyze the prebreakdown processes in $SF_6/N_2$ mixtures stressed by impulse voltages, prebreakdown current and light were observed by a shunt with high sensitivity and a photo-multiplier tube, respectively. Additionally, characteristics of luminous events in flashovers were discussed.

• Korean Journal of Materials Research
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• v.29 no.6
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• pp.363-370
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• 2019

The recent development of information and communication technologies brings new changes to automobile traffic systems. The most typical example is the advancement of dedicated short range communication(DSRC). DSRC mainly consists of an intelligent transportation system(ITS), an electronic toll collection system(ETCS) and an advanced traveler information system(ATIS). These wireless communications often cause unnecessary electromagnetic waves, and these electromagnetic waves, in turn, cause frequent system malfunction. To solve this problem, an absorber of electromagnetic waves is suggested. In this research, various materials, such as powdered metal and iron oxides, are used to test the possibility for an effective absorption of the unnecessary electromagnetic waves. The various metal powders are made into a thin sheet form by compositing through processing. The electromagnetic characteristics(complex permittivity, complex permeability) of the fabricated sheet are measured. As a result, we achieve -6.5 dB at 940 MHz(77.6 % absorption rate) with a 1.0 mm-thickness electromagnet wave absorber, and -9.5 dB at 940 MHz(88.8 % absorption rate) with a 2.0 mm-thickness absorber.

• Journal of Species Research
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• v.12 no.3
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• pp.203-211
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• 2023

Five ciliate species of Euplotes were isolated from fresh and coastal water during a sampling survey to identify unrecorded ciliates in South Korea. Their morphology was investigated using live observation, protargol and "wet" silver nitrate staining methods. Brief descriptions and microphotographs of each species and a comparison with related species are provided. Euplotes focardii is characterized by an average size of 65×47 ㎛ after protargol impregnation, 6 dorsal and 3 ventral ridges and dorsal argyrome pattern of double-eurystomus type. Euplotes nobilii shows an average size of 34×20 ㎛ after protargol staining, 6 dorsal and 3 ventral ridges and dorsal argyrome pattern of double-patella type. Euplotes octocarinatus, the only freshwater species described in the present study, is characterized by an average size of 66×46 ㎛ after protargol impregnation, 6 dorsal and 3 ventral ridges and dorsal argyrome pattern of double-patella type. Euplotes petzi has an average size of 43×30 ㎛ after protargol staining, a macronucleus hook-shaped and dorsal argyrome pattern in double-patella type. Euplotes raikovi is characterized by an average size of 40×24 ㎛ after protargol staining, 6 dorsal and 3 ventral ridges and dorsal argyrome pattern of double-patella type.

• Bulletin of the Korean Mathematical Society
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• v.47 no.6
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• pp.1259-1268
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• 2010

In this paper, we consider an implicit iterative process with errors for an in nite family of strict pseudocontractions. Strong convergence theorems are established in the framework of Banach spaces. The results presented in this paper improve and extend the recent ones announced by many others.

• Computers and Concrete
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• v.28 no.6
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• pp.635-642
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• 2021

In this paper, soft learning techniques are used to predict the ultimate torsional capacity of Reinforced Concrete beams strengthened with Fiber Reinforced Polymer. Soft computing techniques, namely Artificial Neural Network, trained by various back propagation algorithms, and Particle Swarm Optimization (PSO) algorithm, have been used to model and predict the torsional strength of Reinforced Concrete beams strengthened with Fiber Reinforced Polymer. The performance of each model has been evaluated by using statistical parameters such as coefficient of determination (R²), Root Mean Square Error (RMSE), and Mean Absolute Percentage Error (MAPE). The hybrid PSO NN model resulted in an R² of 0.9292 with an RMSE of 5.35 for training and an R² of 0.9328 with an RMSE of 4.57 for testing. Another model, ANN BP, produced an R² of 0.9125 with an RMSE of 6.17 for training and an R² of 0.8951 with an RMSE of 5.79 for testing. The results of the PSO NN model were in close agreement with the experimental values. Thus, the PSO NN model can be used to predict the ultimate torsional capacity of RC beams strengthened with FRP with greater acceptable accuracy.

• Journal of the Korean Magnetic Resonance Society
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• v.3 no.1
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• pp.60-70
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• 1999

The pyrimidine(6-4) pyrimidone photoproduct [(6-4) adduct] is one of the major photoproducts induced by UV irradiation of DNA and occurs at TpT sites. The (6-4) adduct is highly mutagenic and specific during translesion replication. The marked preference for insertion of A opposite the 5'-T and G opposite the 3--T of the (6-4) adducts leads to a predominantly 3'-T\longrightarrowC transition with 85% replicating error rate. In order to obtain insight into the origin of 3'-T\longrightarrowC transition induced by the (6-4) adduct, we have performed one - and two-dimensional NMR experiment. The 3'-Tof the (6-4) lesion forms the stable hydrogen bonding to the imino proton of an opposed G, which stabilizes the overall helix and diminishes the highly distorted conformation caused by the (6-4) lesion in the (6-4)/AA duplex. We proposed that the greater insertion of a G over an A opposite the 3'-T of the (6-4) lesion These results may account for the greater preference for the insertion of a G over a A opposite the 3'-T of the (6-4) lesion. Thus this insertion leads to the highly specific 3'-T\longrightarrowC multation at the (6-4) lesion site.