• BMB Reports
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• v.48 no.1
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• pp.54-59
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• 2015

IL-10-producing B (Breg) cells regulate various immune responses. However, their phenotype remains unclear. CD40 expression was significantly increased in B cells by LPS, and the Breg cells were also enriched in $CD40^{hi}CD5^+$ B cells. Furthermore, CD40 expression on Breg cells was increased by IL-10, CD40 ligand, and B cell-activating factor, suggesting that $CD40^{hi}$ is a common phenotype of Breg cells. LPS-induced CD40 expression was largely suppressed by an anti-IL-10 receptor antibody and in IL-$10^{-/-}CD5^+CD19^+$ B cells. The autocrine effect of IL-10 on the CD40 expression was largely suppressed by an inhibitor of JAK/STAT3. In vivo, the LPS treatment increased the population of $CD40^{hi}CD5^+$ Breg cells in mice. However, the population of $CD40^{hi}CD5^+$ B cells was minimal in IL-$10^{-/-}$ mice by LPS. Altogether, our findings show that Breg cells are largely enriched in $CD40^{hi}CD5^+$ B cells and the autocrine effect of IL-10 is critical to the formation of $CD40^{hi}CD5^+$ Breg cells.

• Parasites, Hosts and Diseases
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• v.54 no.3
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• pp.357-361
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• 2016

Following the first report of Opisthorchis viverrini infection in a domestic duck in Phu My District of Binh Dinh Province, Central Vietnam, many other cases were observed in the province. We determined the infection rate and intensity of O. viverrini infection in ducks in 4 districts of the province. A total of 178 ducks were randomly selected from 34 farms for examination of flukes in the liver and gall bladder. An infection rate of 34.3% (range 20.7-40.4% among districts) was found; the intensity of infection was 13.8 worms per infected duck (range 1-100). These findings show the role of ducks as a host for O. viverrini, duck genotype, which is sympatric with the human O. viverrini genotype in this province. It also stresses the need for investigations on the zoonotic potential and the life cycle of this parasite.

• Journal of the Korean Ceramic Society
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• v.54 no.6
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• pp.492-498
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• 2017

A thermal barrier coating (TBC) with self-healing property for cracks was proposed to improve reliability during gas turbine operation, including structural design. Effect of healing agent on crack propagation behavior in TBCs with and without buffer layer was investigated through furnace cyclic test (FCT). Molybdenum disilicide ($MoSi_2$) was used as the healing agent; it was encapsulated using a mixture of tetraethyl orthosilicate and sodium methoxide. Buffer layers with composition ratios of 90 : 10 and 80 : 20 wt%, using yttria stabilized zirconia and $MoSi_2$, respectively, were prepared by air plasma spray process. After generating artificial cracks in TBC samples by using Vickers indentation, FCTs were conducted at $1100^{\circ}C$ for a dwell time of 40 min., followed by natural air cooling for 20 min. at room temperature. The cracks were healed in the buffer layer with the healing agent of $MoSi_2$, and it was found that the thermal reliability of TBC can be enhanced by introducing the buffer layer with healing agent in the top coat.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.66 no.4
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• pp.375-382
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• 2021

For stable cultivation in double cropping, it is important to use potato (Solanum tuberosum L.) cultivars with a short dormancy period of 50-70 days and plant seed tubers of appropriate type and size. An experiment was conducted during 2018-2019 to investigate the effects of seed tuber type and size on growth and yield performance in double cropping. Whole tubers of three sizes (10-20 g, 30-40 g, and 50-60 g) and conventional cut tubers weighing 30-40 g from three cultivars with different dormancy periods, namely 'Daeji' (40-60 days), 'Eunsun' (50-60 days), and 'Saebong' (50-80 days), were planted, and their field performance was compared. Regardless of the cultivar, the increase in the whole tuber weight up to 30-40 g led to fast emergence, thereby increasing ground cover rate, shoot growth rate, and tuber growth rate, which ultimately improved tuber yield by 33-54%. Comparing the whole and cut tubers, 'Daeji' and 'Eunsun' showed similar growth and yield performance; as such, the performance of whole tubers weighing 10-20 g was comparable to that of cut tubers weighing 30-40 g. However, 'Saebong', a cultivar with relatively long dormancy period, performed better with cut tuber than with whole tubers. Based on these results, we recommend the use of whole tubers weighing over 30 g for double cropping. Further studies to break tuber dormancy are warranted in cultivars with relatively long dormancy periods (50-80 days), such as 'Saebong'.

• Nuclear Engineering and Technology
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• v.54 no.11
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• pp.4265-4271
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• 2022

Determination of ¹³⁷Cs, ⁴⁰K and ²¹⁰Po in water, bottom sediments and suspended matter of river systems of the Can Gio Biosphere Reserve, Vietnam was carried out. The average activity concentration of ¹³⁷Cs in waters of Ca Gau and Long Tau was 0.89 ± 0.14 and 1.08 ± 0.15 Bq m^-3 and was comparable to the levels of this radioisotope in waters of the East Sea. The activity concentration of ¹³⁷Cs in bottom sediments was 2.23 ± 0.81 and 3.63 ± 1.24 Bq kg^-1. The activity concentration of ¹³⁷Cs in water and bottom sediments could be characterized as low. So, the water areas of the Ca Gau and Long Tau rivers could be attributed to areas with insignificant pollution by technogenic radionuclides. The ²¹⁰Po activity concentration in bottom sediments of the Ca Gau and Long Tau rivers ranged from 9.2 ± 1.2 to 25.5 ± 2.1 Bq kg^-1, which is typical for river bottom sediments. Such values indicate the absence of anthropogenic enhancement of the entry of this radionuclide into the Can Gio river systems. The ⁴⁰K activity concentration varied within 467 ± 42-651 ± 39 Bq kg^-1 and represented typical values of potassium content in the bottom sediments of coastal water bodies, subject to a significant influence of the lithogenic component of suspended matter.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.7 no.2
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• pp.47-54
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• 1982

In this paper, a improved per-channel PCM Coder with 1-bit interpolation is proposed. The coder converts a telephone signal to 15-segments u-law PCM signal of a large dynamic range. The A/D conversion technique of the proposed converter requires a feedback loop around a quantizer operates at high speed, and a accumulater for accumulating the quantized values to provide PCM outputs. To obtain both linear and compressed PCM signals a improved table look-up method is presented. The operations of the proposed converter are certified through the experiments to be good. The experimental circuit comprises TTL logic gates, a resistive D/Z converter and a simple differential amplifier. From the results of the experiments, it is known that the proposed converter has many advantage to be adopted economically for per-channel onverter used in rural area service.

• Journal of dental hygiene science
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• v.9 no.3
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• pp.339-344
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• 2009

The purpose of this study was to examine the knowledge of some adults about oral hygiene devices and their use of the oral hygiene devices. After a survey was conducted from December 3 to 17,2007, the answer sheets from 352 respondents were gathered. and the collected data were analyzed with a SPSS Ver. 17.0 program. The findings of the study were as follows. 1. Concerning the level of knowledge, the adults investigated knew the best that a toothbrush should be kept by making the head upward (76.77). On the other hand, they had little knowledge on water pick, tongue cleaner and interdental brush. 2. As for the level of use, they scored highest on keeping their toothbrushes by making the head upward(76.77), In contrast, they scarcely put water pick, electronic toothbrushes, tongue cleaner to use. 3. Knowledge impact of general characteristics involving mate(62.54). 50s over(66.28) and up, four family members(61.54), graduate school graduate(66.78), self-employed and, professionals(63.63), income of 1 to 1.5 million won(66.66), fathers were smokers(51.89) got the highest marks with a mean. 4. Use impact of the general characteristics female(47.70), 40s over 49s under(47.78), four family members(48.18), graduate school graduate(50.17), professionals(49.79), income of 1 to 1.5 million won(51.89), fathers were smokers(48.10) got the highest marks with a mean.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4925-4928
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• 2014

Background: This study aimed to evaluate the methylation of RASSF1A and CDH13 gene promoter regions as a marker for monitoring chemotherapeutic efficacy with personalized medicine for patients with NSCLC, in the hope of providing a new direction for NSCLC individualized chemotherapy. Materials and Methods: 42 NSCLC patients and 40 healthy controls were included. Patient blood samples were collected in the whole process of chemotherapy. Methylation of RASSF1A and CDH13 gene promoter regions was detected by the methylation specific polymerase chain reaction (MSP). Results: The rate of RASSF1A and CDH13 gene methylation in 42 cases of NSCLC patients was significantly higher than in 40 healthy controls (52.4% to 0.0%, 54.8% to 0.0%, p<0.05). After the chemotherapy, the hyper-methylation of RASSF1A and CDH13 genes in PR group and SD group decreased significantly (p<0.05), and was significantly different from that in PD group (p<0.05), but not as compared with healthy controls (P>0.05). With chemotherapy, RASSF1A and CDH13 promoter region methylation rate in 42 cases of patients showed a declining trend. Conclusions: The methylation level of RASSF1A and CDH13 gene promoter region can reflect drug sensitivity of tumors to individualized treatment.

• Korean Chemical Engineering Research
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• v.54 no.6
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• pp.806-811
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• 2016

Organosolv pretreatment is the process to frationation of lignocellulosic feedstocks to enhancement of enzymatic hydrolysis. This process has advantages that organic solvents are always easy to recover by distillation and recycled for pretreatment. The chemical recovery in organosolv pretreatment can isolate lignin as a solid material and carbohydrates as fermentable sugars. For the economic considerations, using of low-molecular-weight alcohols such as ethanol and methanol have been favored. When acid catalysts are added in organic solvent, the rate of delignification could be increased. Mineral acids (hydrochloric acid, sulfuric acid, and phosphoric acid) are good catalysts to accelerate delignification and xylan degradation. In this study, the biomass was pretreated using 40~50 wt% ethanol at $170{\sim}180^{\circ}C$ during 20~60 min. As a results, the enzymatic digestibility of 2-stage pretreatment of rigida using 50 wt% ethanol at $180^{\circ}C$ was 40.6% but that of 1-stage pretreatment was 55.4% on same conditions, therefore it is shown that the pretreatment using mixture of the organosolv and catalyst was effective than using them separately.

• Journal of Yeungnam Medical Science
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• v.7 no.2
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• pp.55-66
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• 1990

This research is focused on the attitudes toward dying and hospice. 4subjects groups are Ca. patient, Ca. patien's family, elderly, medical personnel. A 40 questionare was filled out by each participant. For this study chi-square and T-test was done. The result were as follows : 1. Telling the truth 61.2% of all subject groups agreed upon telling the impending death. About 40% of elderly groups and cancer patient group were disagreed which is the highest percentage in all groups. Particularly medical personnel group were remarkably high in telling the truth. 2. Attitudes of medical personnels 43.3% of all groups agreed upon medical personnels prefer to avoid dying patient. In medical personnel group. 44% of respondents disagred comparably higher than other group. But 37.7% of medical personnel agreed. It showed that medical personnels admitted their negative feelings toward dying patient in considerable degree. 3. Attitudes toward mechanical assistance for life-expanding or hopeless patient. 44.8% of all groups disagreed upon mechanical assistance for hopeless case. Elderly (54.9%) and medical personnels (50%) disagreed, which is higher than cancer patient (33.3%) and (22.8%) of cancer patient's family. 4. Special facility and educational preperation for dying patient. 67.4% of all groups agreed upon the needs of special facility for dying, 81.3% of medical personnels agreed which is highest percentage in all group. 5. Attitudes of family members of dying patient. 82.3% of all groups agreed upon the family members feel annoyed at dying patient. 34% of cancer patient's family member and 48% of cancer patients group agreed, but elderly group showed highest percentage(84%). 6. Perception of dying patient about imminent death. 58.3% of all group thought dying patients are aware of their impanding death even though they had not beent told. 77.3% of medical personnel agreed which is highest percentage in all group.