• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.873-876
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• 2003

Z-map model is the most widely used model for NC simulation and verification. But it has several limitations to get a high precision, to apply 5 axis machining simulation. In this paper, we tried to use quadtree for searching cutting region. Quadtree representation of two dimensional objects is performed with a tree that describes the recursive subdivision. By using these quadtree model. storage requirements were reduced. And also, recursive subdivision was processed in the boundries, so, useless computation could be reduced, too. To get more high Accuracy, we applied the supersampling method in the boundaries. The Supersampling method is the most common form of the antialiasing and usually used with polygon mesh rendering in computer graphics To verify quadtree model we compared simulated results with z-map model and enhanced z-map model

• 한국CDE학회논문집
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• 제10권2호
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• pp.107-113
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• 2005

Octree-based algorithm is developed for machining simulation. Most of commercial machining simulators are based on Z map model, which have several limitations to get a high precision in 5 axis machining simulation. Octree representation is three dimensional decomposition method. So it is expected that these limitations be overcome by using octree based algorithm. By using the octree model, storage requirement is reduced. And also recursive subdivision was processed in the boundaries, which reduces useless computation. The supersampling method is the most common form of the anti-aliasing and usually used with polygon mesh rendering in computer graphics. Supersampling technique is applied for advancing its efficiency of the octree algorithm.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1995년도 춘계학술대회 논문집
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• pp.97-101
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• 1995

This paper describes a new surface finishing process which uses magnetic abrasive polishing. This is applied to automatic finishing of die & mold surface. Nowadays, most of die & mold meanufaturing procedures have been automated by the introduction of NC machine tool and CAD/CAM system. But the surface finishing of die & mold must be done by hand work of well-skilled workers. Though many attempts were tried in the past 15 years to eliminate this hand work, the automatic finishing of die & mold surface with 3D curvature has not been achieved yet. New magnetic abrasive finishing process is thought as one of the possible methods for the automation of 3D surface finishing. In order to improve the grindability of the method, ultra-high speed and 5-axis machining was introduce. The magnetic abrasive polishing which has adopted these methods was confirmend to improve the efficiencyof die & mold surface finishing.

• 한국강구조학회 논문집
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• 제26권5호
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• pp.385-396
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• 2014

1994년 미국 노스리지 지진 당시 상당 부분의 피해가 보 하부 플랜지에서 발생하였는데, 이의 원인으로 여러 가지가 거론되었지만 바닥슬래브와 합성작용에 의한 중립축 상승이 주요한 역학적 원인으로 인정되고 있다. 국내의 경우 지진에 저항하는 모멘트골조에 속하는 보(moment frame beam)의 경우에 순철골보로서 설계하고도 실제 시공시에는 보 상부 플랜지에 전단스터드를 필요 이상으로 과도하게 배치하는 오랜 관행이 존재하고 있어 내진성능 확보 차원에서 문제를 유발할 소지가 있다. 본 논문에서는 의도하지 않은 또는 과도한 합성작용이 내진성능에 미치는 부작용을 실물대 실험을 통해 재현하고 이의 개선방향을 모색하고자 하였다. 국내 관행에 따른 접합상세와 합성바닥구조를 갖는 실험체(PN700-C)의 경우, 합성도가 23% 정도임에도 불구하고, 상부플랜지 압축응력에 대해 중립축이 현저히 상승하였고 결국 3% 층간변위에서 콘크리트 압괴를 수반하면서 하부플랜지 취성파단이 발생하였다. 반면 합성바닥이 포함되어 있으나 합성작용이 최소화되도록 설계된 RBS접합부실험체(DB700-C)는 순철골(비합성) RBS접합부실험체(DB700-NC)와 유사한 이력거동을 보이면서 어떤 취성파괴도 없이 5% 수준의 뛰어난 층간변형 능력을 발휘하였다. 본 연구결과는 강구조접합부의 내진보강이나 신축에 있어 모멘트골조에 속한 철골보 및 접합부는 바닥구조와의 합성작용이 최소화되도록 설계 및 시공되어야 함을 시사한다.

• 한국작물학회지
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• 제31권3호
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• pp.270-276
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• 1986

배추 및 고추재배지에 NC2326 품종을 공시하여 적정시비양 및 적심정도를 구명코자 본 시험을 발행하였던 바 그 결과는 다음과 같다. 1. 배추 및 고추재배지 토양은 휴경지에 비하여유기물, 전질소, 질소함양이 높게 나타났다. 2. 전작물의 종류에 따라서 수량은 배추>고추 순이었고 증비할수록 증수효과가 컸으며 적심정도에 따라서는 꽃망울제법>치엽2매>치엽4매 적심구 순이었다. 3. 품질은 배추재배지에서 연초용 복합비료를 10a당 50kg, 고추재배지에서 75 시용할 때 가장 양호하였으며 적심정도에서는 치엽2매 적심에서 가장 양호하였 다. 4. 수확건조엽중 Nicotine 및 전질소함양은 배추재배지>고추재배지 순이었으며 증비할수록 증가하는 경향이였고 염소의 함양변화도 같은 경향이었다. 환원당은 고추재배지보다 배추재배지에서 낮았으며 증비할수록 감소하였다. 5. 연초재배는 배추재배지에서 연초용 복합비료를 10a당 50-75kg, 고추재배지에서는 75kg 절위가 좋고 토성 및 비첨도 등에 따라 적절히 가감 시용할 것이며 적심은 치엽 2매를 붙여서 하는 것이 양질엽 생산을 위하여 가장 이상적일 것으로 생각된다.

• Molecules and Cells
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• 제41권5호
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• pp.423-435
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• 2018

This investigation was aimed at working out the combined role of lncRNA H19, miR-29b and Wnt signaling in the development of colorectal cancer (CRC). In the aggregate, 185 CRC tissues and corresponding para-carcinoma tissues were gathered. The human CRC cell lines (i.e. HT29, HCT116, SW480 and SW620) and normal colorectal mucosa cell line (NCM460) were also purchased. Si-H19, si-NC, miR-29b-3p mimics, miR-29b-3p inhibitor, si-PGRN and negative control (NC) were, respectively, transfected into the CRC cells. Luciferase reporter plasmids were prepared to evaluate the transduction activity of $Wnt/{\beta}-catenin$ signaling pathway, and dual-luciferase reporter gene assay was arranged to confirm the targeted relationship between H19 and miR-29b-3p, as well as between miR-29b-3p and PGRN. Finally, the proliferative and invasive capacities of CRC cells were appraised through transwell, MTT and scratch assays. As a result, overexpressed H19 and down-expressed miR-29b-3p displayed close associations with the CRC patients' poor prognosis (P < 0.05). Besides, transfection with si-H19, miR-29b-3p mimic or si-PGRN were correlated with elevated E-cadherin expression, decreased snail and vimentin expressions, as well as less-motivated cell proliferation and cell metastasis (P < 0.05). Moreover, H19 was verified to directly target miR-29b-3p based on the luciferase reporter gene assay (P < 0.05), and miR-29b-3p also bound to PGRN in a direct manner (P < 0.05). Finally, addition of LiCl ($Wnt/{\beta}-catenin$ pathway activator) or XAV93920 ($Wnt/{\beta}-catenin$ pathway inhibitor) would cause remarkably altered E-cadherin, c-Myc, vimentin and snail expressions, as well as significantly changed transcriptional activity of ${\beta}-catenin/Tcf$ reporter plasmid (P < 0.05). In conclusion, the lncRNA H19/miR-29b-3p/PGRN/Wnt axis counted a great deal for seeking appropriate diagnostic biomarkers and treatment targets for CRC.

• 한국정밀공학회지
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• 제17권6호
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• pp.162-168
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• 2000

The automatic die polishing machine by liquid honing has been developed and experimented on the surface of machined die. The goal of development in the automatic die polishing machine by liquid honing is to increase the accuracy and the productivity in die polishing. To reach this goal, the polishing machine consists of the automatic measuring device for contour of die, the nozzle and pumping system to spray the powder mixed with liquid, and the 3-axis guides. Before polishing, the measuring device with a semiconductor laser scans the surface of mould to get the data of contour. The data store a PC and use to control the nozzle head to move above a couple of centimeters on the machined surface of die. The experimental parameters are the spraying time, the pressure, the size of abrasive grain and the mixing ratio between abrasive grain and liquid. The surface roughness is measured on the polished die which are SKDl 1 and Al7075 machined by NC. The surface roughness indicates the values of Rmax 0.5${\mu}{\textrm}{m}$ for Al7075 and Rmax 1.4${\mu}{\textrm}{m}$ for SKDl 1. It reduces the polishing time significantly and reduces the monotonous work for labors. As the results, the liquid honing system is useful method to apply for the die polishing and the automatic die polishing machine using liquid honing shows that it's very effective processing ability.

• 한국결정학회지
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• 제5권1호
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• pp.1-6
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• 1994

화합물 VP6N3018C243H60의 두 가지 가능한 공간군은 PT,a=14.O22(1), b=12.644(2), c=12.640(1)A, a=80.38(1), β=102.12(1), y =102.16(1), V=2124.1A3, Z=2, u=0.47cm-1,d==1.46g/cm3, Fo>4c IfoI인 3350윤의 독립반사강도에 대하여 R=0.083 과 C2/c, a=19.32(2), b=16.32(2), c=14.02(1)A, β= 105.98(5), V=4348.2A3, Z=4, Fo>4o IFoI인 1590개의 독립반사강도에 대하여 R=0.083 이다. 주간군 Pi의 경우 단위포내에 두 분자가 있는데 각 분자내의 바나둠 원자가 특수치치에 있어 중심대칭에 의하여 한 분자를 이루고 있으므로 단위포내의 비대칭단위는 두개의 bis(timetalhosphate)vanadate 반분자와 3개의 tetraethylammDnium분자로 되어있다. 공문군 C2/c의 경우 bis(trimetaphosphate)vanadate 한분자의 vanadium 원자가 중심대1칭을 갖는 변광단동치에 있으며, 3개의 tetrethylammonium 분자중 한 분자내의 CL2, N2, C25 원자들을 2-회회전대칭축이 지나므로 bis(trimetaphosphate)vanadate 반분자와 tetraethylammonium 3/2 분자가 비대칭단위를 이루고 있다. 두 경우 공히 vanadium원자를 배위하고 있는 6개의 산소원자가 8함체를 이루며 nitrogen원자와 결합하고 있는 4개의 carbon 원자들은 모두 disorder되어 있어 nitrogen원자의 주권에 있는 8개의 carbon 원자들은 불규칙한 12면체를 이루고 있다.

• 천문학회지
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• 제24권2호
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• pp.217-271
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• 1991

We have observed dense core around young stellar objects, DR21, S140, Orion-KL, and L1551 using four millimeter-wave transitions of $HC_3N\;J$=4-3, J=5-4, J=10-9, and J=12-11. The spatial distribution of $HC_3N$ emission closely resembles the morphology of the previous CS observations that trace high density gas. These observations reveal the existence of $HC_3N$ dense cores around central IR source, elliptical in shape and almost perpendicular to the CO bipolar outflow axis. Small differences can be explained by that $HC_3N$ molecular line is more optically thin and is seen to be more detailed structure in the neighborhood of central IR sources. In S140 and Orion-KL, massive(${\sim}10\;M_{\odot}$), slowly rotating dense cores lie near at the central IR sources of bipolar outflows. The velocity channel maps of DR21 show that the bipolar outflow gas may have a correlation with the dense core of DR21. We analyzed intensities of the four lines to derive physical conditions in dense core from two methods, LTE and LVG. The column density of $HC_3N$, $N(HC_3N)$, between LTE and LVG calculations agree well with each other. The abundances of $HC_3N$ in each observing source have been estimated using the average values of $n(H_2)$ and $N(HC_3N)$ and assuming the size of dense core. The fractional $HC_3N$ abundances in massive dense cores of DR21, S140, and Orion-KL have a range of $(2-7){\times}10^{-10}$, while that of low mass dense core, L1551, has one order of magnitude greater value of $2{\times}10^{-9}$. This should be considered good agreement with the result by Morris et al.(1976). It may be considered that dense cores of DR21, S140, and Orion-KL may have almost same stage of chemical evolution, and their abundances have a small values relative to that of L1551. The column density $N(HC_3N)$ decreases with increasing distance from the densest part of the cloud, the central infrared source, and have the relation of $N(HC_3N){\varpropto}R^{\alpha}$, where a has a range of 0.65 to 0.89. The values of $n(H_2)$ are not varied with increasing distance from the dense core, and have almost same values. Therefore, it is considered that the dense cores in these regions probably consist of dense clumps in diffuse molecular gas medium, and $n(H_2)$ of each clump is ${\sim}10^5\;cm^{-3}$. Levels in the $T_{ex}$ increases with $n(H_2)$. It is considered that the $HC_3N$ dense cores are not completely thermalized. We examine the relationships between the luminosity of central infrared sources versus mass of the dense cores, and the luminosity of central infrared sources versus molecular hydrogen column density. Luminosities of the central IR sources show good correlation with mass and hydrogen column density of the dense core. Same has been found from CS observations. However, mass and size derived from $HC_3N$ observations are one order of magnitude smaller than those from CS. It can be interpreted that we see more central part of the cloud cores in $NC_3N$ lines than CS lines.