• Journal of Korean Academy of Nursing
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• v.33 no.2
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• pp.170-178
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• 2003

Purpose: This study was to determine the effect of oral vitamin C supplements on blood sugar and antioxidative status in Types II diabetes mellitus patients. Method: Data for the study were collected from June 24 to August 31, 2001. Participants(31) took 1g/day vitamin C for 4 weeks, after a 1 - week taking no Vitamin C, followed by Vitamin C 3g/day for 4 weeks. A baseline blood sample was obtained following a 12hour overnight fast and at the end of each 4week Vitamin C administration. Blood samples were taken for plasma vitamin C concentration, fasting blood sugar, HbA1c, superoxide scavenging activity and hydrogen peroxide scavenging activity. The data were analyzed by SPSS for repeated measures ANOVA. Result: Plasma vitamin C concentration was significantly increased over dose(F=3.316, p=.043). Fasting blood sugar and HbA1c was significantly decreased over dose(F=13.192, p=.000; F=11.995, p=.000). Superoxide scavenging activity and hydrogen peroxide scavenging activity was significantly increased over dose(F=486.138, p=.000; F=177.704, p= .000). Conclusion: The results suggest that megadose vitamin C supplementation may have a beneficial effect in diabetes mellitus patients on both glycemic control and antioxidant status. Thus dietary measures to increase plasma vitamin C may be an important health strategy for reducing the compliance of diabetic patients

• Journal of muscle and joint health
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• v.5 no.2
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• pp.253-264
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• 1998

This study has done for the purpose of investigation among the degrees of pain coping strategies, pain, and depression of patients with rheumatoid arthritis. The subjects of this study were 214 patients diagnosed with rheumatoid arthritis. The data were collected from september 4 to 16, 1995 by questionnaires. The data were analysed by the use of frequency, t-test, Pearson Correlation Coefficients, ANOVA, and Duncan test. The results Were as follows ; 1. The mean score of pain was 213.5(range : 4-390) and that of depression was 21.4 (range : 1-50). The mean score of passive pain coping strategies was 30.2(range : 11-48) and that of active pain coping strategies was 18.6(range : 7-33) 2. The passive pain coping degree showed a positive correlation with the pain degree (r=.475, p=.0001) and the active pain coping degree showed a inversive correlation with that(r= -.296, p=.0001). The passive pain coping degree showed a positive correlation with the depression degree (r=.425, p=.0001) and the active pain coping degree showed a inversive correlation with that(r=-.299, p=.0001). The pain degree showed a positive correlation with the depression degree(r=.374, p=.0001).

• Korean Journal of Adult Nursing
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• v.20 no.4
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• pp.652-663
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• 2008

Purpose: This study was conducted to develop and test an explanatory model on functional capacity in patients with chronic obstructive pulmonary disease using path analysis. Methods: Data were collected from 149 chronic obstructive pulmonary disease patients using 6-minute walk test, measurement of oxygen saturation, pulmonary function test, and self-reported questionnaires from June to October, 2005. The collected data were analyzed using SPSS/WIN 12.0 program and AMOS/WIN 4.0 program. Results: The overall fitness indices of modified model were good($x^2$ = 14.324, p = .281 GFI = .981, RMSEA = .006, AGFI = .944, NFI = .927, NNFI = .999, CFI = .999, PNFI = .613, $x^2$/df = 1.194). Functional capacity was influenced directly by age(${\beta}$ = -.304, p = .000), dyspnea(${\beta}$ = -.278, p = .000), self-efficacy(${\beta}$ = .240, p = .000), social support(${\beta}$ = .175, p = .004), pulmonary function(${\beta}$ = .169, p = .008), and oxygen saturation(${\beta}$ = .099, p = .048). These variables explained 39.3% in functional capacity. Conclusion: The findings of this study suggest that comprehensive nursing interventions should focus on decreasing dyspnea and increasing self-efficacy, social support, and oxygen saturation. In this perspective, pulmonary rehabilitation would be an effective strategy for improving functional capacity in patients with chronic obstructive pulmonary disease.

• Journal of Integrative Natural Science
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• v.16 no.1
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• pp.39-45
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• 2023

P2X receptors are ATP-activated ion channels in the plasma membrane. P2X receptors have a role in a diverse range of disorders, making them a valuable therapeutic target. Hence, the present investigation employed homology modelling of the P2X receptor based on the crystal structure of 5SVJ, 6AH4, 5YVE and 5SVL. Twenty models, using both single- and multiple template-based methods, were developed, and the best model was chosen based on the validation result. We observed that a strategy based on multiple templates provided greater accuracy. Future studies involving binding site and docking analysis can make use of the produced structures.

• Journal of Applied Biological Chemistry
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• v.49 no.4
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• pp.157-161
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• 2006

The performance of abiotic degradation of oxadiazon was investigated by applying zerovalent iron(ZVI), potassium permanganate($KMnO_4$) and titanium dioxide($TiO_2$) in the contaminated water. Experimental conditions allowed the disappearance of oxadiazon in the abiotic system. The degradation of this herbicide was monitored in buffer solutions having pH 3, 5 and 7 in the presence of iron powder in which the maximum degradation rate was achieved at acidic condition(pH 3) by 2% of ZVI treatment. The oxidative degradation of oxadiazon was observed in aqueous solution by $KMnO_4$ at pH 3, 7 and 10 in which the highest disappearance rate was found at neutral pH when treated with 2% of $KMnO_4$. The catalytic degradation of oxadiazon in $TiO_2$ suspension was obtained under dark and UV irradiation conditions. UV irradiation enhanced the degradation of oxadiazon in aquatic system in the presence of $TiO_2$. Conclusively, the remediation strategy using these abiotic reagents could be applied to remove oxadiazon from the contaminated water.

• The Korean Journal of Ecology
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• v.16 no.4
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• pp.417-428
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• 1993

Branching growth pattern of Mugnolza denuduta is likely to be originated from two growth strategies: environment overcoming strategy and life maintenance strategy, which coexist in a tree. Growth rate of branches was strongly correlated with relative light intensity (P<0.001) and physical contact (P<0.01), however there is no significant correlation between growth rate and direction of branch. When relative light intensity is less than 1%, the growth was restricted by physical contact with the surrounding branches. In contrast, the growth was rarely restricted by physical contact when relative light intensitiy was 10% or more. The branching rate was significantly affected by the presence or absence of physical contact (P<0.05), but it was not significantly affected by relative light intensity nor by the direction of branch. In the beginning stage of the growth, the ratio of the material allocation from main branch to subbranch was large and varied with the influence of surrounding environment. These various growth rates, which implicate a variety of material allocation ratios (0.16~0.98), affect branch growth pattern through the optimum growth strategies. The growth and arrangement of branches of Magnolia denudata display the solar collectors to maximize the total amount of energy absorbed and to overcome the restriction of the environment.

• Korean Journal of Community Nutrition
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• v.15 no.4
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• pp.550-559
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• 2010

The study was conducted to assess school dietitians' preferences for traditional foods, to determine the association with their perception and usage status, and to develop the strategies to increase its utilization of traditional foods in school lunches. The information was obtained by the self-administered questionnaire from the subjects, which were 198 dietitians in schools located in Seoul and Gyeonggi-do. According to the preference for traditional foods, subjects were distributed into three groups (High = 54, Medium = 128, Low = 16). The significances of differences between groups were determined using SPSS 12.0 at p < 0.05. Compared to the dietitians with lower (medium and low) preferences, those with high preferences answered that they had better knowledge (p < 0.001) for traditional foods, and served them more in school lunches (p < 0.01). Also, more dieticians in the high preference group not only felt that they need to train school administrators (p < 0.01) as well as themselves (p < 0.05), but also were currently providing students with the nutrition education on traditional foods (p < 0.05). The results presented the evidence suggesting that having dietitians with higher preference for traditional foods can offer an effective strategy to increase the opportunities for schoolchildren to be exposed to traditional foods. Development of the standard recipes for use in school lunches by the government or the association was answered as the best strategy to increase the use of traditional foods, regardless of the dietitians' preferences.

• Journal of Korean Society of Environmental Engineers
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• v.28 no.12
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• pp.1293-1303
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• 2006

This paper represents a comparison the difference between existence and nonexistence of soundproof trees for road traffic noise. Also we suggested that the simple equation has been derived using a single regression analysis for predicting levels of $Leq_{th}$ at a given distance from a road in terms of the flow rate, the mean speed of the traffic, and the percentage of the type vehicles in the existence and nonexistence of soundproof trees. We classified a vehicle into four and analyzed contribution rate to traffic volume. As a result, the order showed as followed: light vehicle>medium vehicle>heavy vehicle>motorcycle. However, the results of analyzing contribution rate with between traffic volume and traffic noise by the each type showed as followed; Motorcycle>Light vehicle>Medium vehicle>Heavy vehicle. This study showed that the most a lof of traffic volumes of the three vehicles(light vehicle, medium vehicle and motorcycle) and heavy vehicle were existed in 67 km/h and 61 km/h of car speed, respectively. The total traffic noise to the mean car speed decreased because of the inflow a lot of traffic volumes between 2016 and 2388 in the range of 67 km/h of light vehicle speed, in traffic composition of 4.75% heavy vehicles, and 1.11% motorcycle. the final result for this study showed that statistical paired t-test for between existence and nonexistence of soundproof trees was significant(p<0.05) and the difference between daytime and night in the location of the nonexistence of plant communities with the independent sample T-test was significant(p<0.05). However, the independent sample T-test for analyzing the variance of traffic noise between daytime and night was not significant(p>0.05).

• Hwankyungkyoyuk
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• v.21 no.3
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• pp.13-25
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• 2008

This study examined the educational effects of journal writing on environmental literacy of elementary students. Thirty-one 3rd grade students were involved in the journal writing which is considered as one of the most frequently performed writing activities in elementary students. Topics for the journal writing were chosen from a textbook on the environment. Before and after the journal writing, an instrument was used to measure the environmental literacy of the students. The environmental literacy instrument was originally developed by Jin (2004) then were modified by Kim (2005) for elementary students. The results of this study are as follows. The environmental literacy of the students, on average, was improved from 140.84 (74.5%) to 161.84 (85.6%) after the journal writing and the difference was statistically significant(t=7.46, p<.001). The environmental literacy scores were significantly improved in every variable after the journal writing: ecological knowledge(t=3.60, p<.01), environmental sensitivity(t=2.54, p<.05), knowledge of environmental issues(t=3.11, p<.01), environmental attitude(t=5.92, p<.001), environmental concern(t=5.27, p<.001), sense of environmental crisis(t=2.97, p<.01), environmental issue investigation and action strategy knowledge (t=2.34, p<.05), environmental skill(t=4.86, p<.001), locus of control(t=5.63, p<.001), and responsible environmental behavior(t=4.64, p<.001). This study also shows that improvement of the students was statistically significant in each of the four levels of goals in environmental education: EE goal level I (t=4.22, p<.001), level II (t=7.53, p<.001), level III(t=5.01, p<.001), and level IV(t=5.46, p<.001). The results imply that the journal writing on the environment is effective in cultivating elementary students' environmental literacy and in achieving goals in environmental education.

• Journal of Periodontal and Implant Science
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• v.33 no.4
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• pp.543-553
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• 2003

Due to considerably high degree of sequence homology between bacterial and human heat shock proteins(hsp), it has been widely thought that this protein might be involved in autoimmune disease mechanisms in humans. To elucidate how stress proteins contribute in the immunopathogenesis of periodontitis, the present study was performed to evaluate the T cell immune responses specific to Porphyromonas gingivalis (P. gingivalis) heat shock protein (hsp)60 and T-cell epitope specificities for P. gingivalis hsp60 in periodontitis. Anti-P. gingivalis IgG antibody titers were elevated in all patients. We could establish P. gingivalis hsp-specific T cell ines from the peripheral blood of peridontitis, a mixture of $CD4^+$ and $CD8^+$ cells. Of 108 overlapping synthetic peptides spanning whole P. gingivalis hsp60 moleculc, ten peptides with cpitopes specifities for T-cell were showed. Interestingly, ten epitopes were also identified as T-cell epitopes in the present study as well as B-cell epitopes in peridontitis. Therefore, all the ten representative epitopes were designated as common T-and B-cell epitopes for peridontitis. It is critical in developing a peptide vaccine strategy for potential prevention of periodontitis. It was concluded that P. gingivalis hsp60 might be involved in the immunoregulatory process of periodontitis with heat shock protein specificities.