• 제목/요약/키워드: 4P strategy

검색결과 874건 처리시간 0.027초

Specific urinary metabolites in canine mammary gland tumors

  • Valko-Rokytovska, Marcela;Ocenas, Peter;Salayova, Aneta;Titkova, Radka;Kostecka, Zuzana
    • Journal of Veterinary Science
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    • 제21권2호
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    • pp.23.1-23.10
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    • 2020
  • The identification of biomarkers that distinguish diseased from healthy individuals is of great interest in human and veterinary fields. In this research area, a metabolomic approach and its related statistical analyses can be useful for biomarker determination and allow non-invasive discrimination of healthy volunteers from breast cancer patients. In this study, we focused on the most common canine neoplasm, mammary gland tumor, and herein, we describe a simple method using ultra-high-performance liquid chromatography to determine the levels of tyrosine and its metabolites (epinephrine, 3,4-dihydroxy-L-phenylalanine, 3,4-dihydroxyphenylacetic acid, and vanillylmandelic acid), tryptophan and its metabolites (5-hydroxyindolacetic acid, indoxyl sulfate, serotonin, and kynurenic acid) in canine mammary cancer urine samples. Our results indicated significantly increased concentrations of three tryptophan metabolites, 5-hydroxyindolacetic acid (p < 0.001), serotonin, indoxyl sulfate (p < 0.01), and kynurenic acid (p < 0.05), and 2 tyrosine metabolites, 3,4-dihydroxy-L-phenylalanine (p < 0.001), and epinephrine (p < 0.05) in urine samples from the mammary gland tumor group compared to concentrations in urine samples from the healthy group. The results indicate that select urinary tyrosine and tryptophan metabolites may be useful as non-invasive diagnostic markers as well as in developing a therapeutic strategy for canine mammary gland tumors.

Correlation of Hemoglobin and RBC count with Adiponectin Level

  • Shim, Moon-Jung
    • 대한임상검사과학회지
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    • 제44권4호
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    • pp.222-228
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    • 2012
  • Adiponectin is secreted specifically by adipose tissue and regulates lipid and glucose metabolism. In addition, adiponectin has been found to inhibit inflammatory process and possibly atherogenesis. This study was done to compare hematological parameters, serum lipids with serum adiponectin level according to body mass index (BMI) and gender in eighty eight Korean adults aged 40 to 68. In this study, the association between serum adiponectin and other variables including RBC counts, hemoglobin, hematocrit and albumin were investigated. RBC, hemoglobin status, was inversely associated with serum adiponectin levels in normal adult women. Adiponectin levels were significantly lower in men than women (p<0.01). In men, serum adiponectin levels were negatively correlated with body mass index (BMI) (p<0.05). However, no correlations were found in women. These results might imply that the regulation of key adipokines such as adiponectin might be a strategy for the prevention or treatment of obesity-associated diseases.

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도서관학 5법칙으로 본 P대학도서관 운영과 개선방안 (A Study on Management and Improvement of P University Libraries with Viewpoint of Five Laws of Library Science: Focused on the first law and the fifth law)

  • 전선구;이용재
    • 한국도서관정보학회지
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    • 제54권3호
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    • pp.57-80
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    • 2023
  • 이 연구의 목적은 도서관학 5법칙을 통하여 대학도서관 운영의 현황을 살펴보고 그 개선방안을 제시하는 것이다. 이를 위해 연구의 범위를 부산지역으로 하여 국·공립대학 도서관 4곳의 운영 현황을 분석하였고, 또한 심층조사를 위하여 부산의 P대학도서관을 사례로 살펴보았다. 부산지역 국·공립 대학도서관 운영 현황은 2018~2022년 동안의 대학도서관 소장 및 구독자료, 시설, 인력자원, 자료 구입비, 이용 및 이용자의 범주로 구분하여 분석하였다. 특히 코로나19로 인한 이용자 감소와 사서의 부족 문제가 나타났다. 사례연구에서는 랑가나단의 도서관학 5법칙 중 제1법칙과 제5법칙을 중심으로 P대학도서관 운영 현황을 조사하였다. 제1법칙에서는 장서에 대한 접근 방식 및 이용 활성화, 도서관 입지, 이용 시간 및 도서대출, 직원의 측면으로 구분하여 조사하였고, 제5법칙에서는 P대학도서관의 디지털 기술 변화에 따른 서비스 개선 측면과 이용자 특성 변화에 따른 도서관 환경 개선 측면으로 나누어 조사하였다. 연구의 결과, 개선방안으로 '도서관 공간구성 전략 수립', '블루오션 전략 수립', '사서의 채용과 배치 확대'를 제시하였다.

중년기 여성의 우울과 자아정체감에 관한 연구 (Study on Depression and Ego Identity of Middle-aged Women)

  • 김혜영;고효정
    • 여성건강간호학회지
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    • 제3권2호
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    • pp.129-156
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    • 1997
  • The purpose of this study is to investigate the relationship between depression and ego identity of middle-aged women and to identify the variables that show differences in the depression and ego identity of middle-aged women. The subjects in the study were 321 mothers of high school students whose age were 40-59 years old. The instruments for this study were Beck Depression Inventory(BDI) developed Beck(1978) and translated by Lee(1981) and Ego identity Scale developed Suh(1975) and modified by Nam(1975). The reliability values of BDI range from 0.83 to 0.87 and Ego identity range from 0.81 to 0.85 using Cronbach alpha. The data were analysed by using the SAS program and included Frequency, percentage Pearson Correlation MANOVA, t-test, ANOVA. The conclusion obtained from this study were as follows ; 1) There was a negative correlation(r=-0.21, p=0.0002) between depression and ego identity of middle-aged women. Thus the lower depression the higher ego identity for middle-aged women. 2) According to the analysis of interacting effects of depression and ego identity, there were significant differences in the household income(F=0.38, p=0.0035), level of education (F=6.50, p=0.0001), satisfaction of marriage(F=10.45, p=0.0001), family pattern (F=6.18, p=0.0001), menopausal status(F=7.23, p=0.0001), present disease(F=4.85, p=0.0110) and health status(F=9.00, p=0.0001). 3) There were significant differences on the level of education(F=12.98, p=0.0001) household income(F=5.78, p=0.0007), support of spouse(F=8.58, p=0.0002), satisfaction of marriage(F=20.08, p=0.0001), menopausal status(F=11.32, p=0.0001), present disease(t=2.76, p=0.0062) and health status(F=17.23, p=0.0001) of the depression of middle-aged women. 4) There were significant differences on the patterns of household(t=-2.64, p=0.0086), support spouse(F=3.58, p=0.0291), satisfaction of marriage(F=3.90, p=0.0212), menopausal status(F=4.59, p=0.0108) and disease(t=2.11, p=0.0359) of the ego identity of middle-aged women. On the basis of the above findings the following recommendations are made ; 1) According to results of this study, middle-aged women's depression is correlated with ego identity. Thus when the nurse plans the preventive strategy of middle-aged women's depression, the nurse must be considered with level of ego identity. 2) To study for middle-aged women in depth, further research is need to study regard to middle-aged men and their children.

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고등학생의 음주행동 영향요인 (Factors Associated with Drinking Behavior in High School Students)

  • 박경민;양윤경
    • 보건교육건강증진학회지
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    • 제30권2호
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    • pp.83-92
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    • 2013
  • Objectives: The purpose of this study was to investigate factors affecting the drinking behavior in high school students. Methods: There were 620 subjects who were first and second graders of seven high schools in Daegu. This study used Sinhaengwoo (1998)'s drinking behavior scale, Rowlison and Felner (1988)'s stress scale, Kovacs (1981)'s children's depression inventory, Rosenberg (1965)'s self-esteem scale. The data were analyzed by descriptive statistics, Pearson's correlation coefficient, and stepwise multiple regression using SPSS/win 18.0 program. This study was approved by the Institutional Review Boards (IRB) of the Keimyung university hospital(No. 12-112). Results: The mean score for drinking behavior in high school students was 23.1points. Factors influencing drinking behavior in high school students were identified as self-esteem(t=-3.67, p<.001), stress(t=6.79, p<.001), school types(t=4.02, p<.001), sex(t=-3.67, p<.001). These factors explained 27% of drinking behavior reported by high school students. Conclusion: The results indicate which factors are majors influencing drinking behavior in high school students. Therefore, self-esteem enhancement could be considered as an effective strategy to reduce the drinking behavior in high school students.

간호사가 인지한 서번트 리더십, 의사소통능력과 감정노동의 관계 (Correlations among Emotional Labor, Servant Leadership, and Communication Competence in Hospital Nurses)

  • 박나경;이현경;이태화;박정숙
    • 한국직업건강간호학회지
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    • 제24권2호
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    • pp.57-66
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    • 2015
  • Purpose: The purpose of this study was to identify correlations among emotional labor, servant leadership, and communication competence in hospital nurses. Methods: A self-administrated survey was conducted with a convenient sample of 210 nurses, using a structured questionnaire. The data were analyzed by descriptive statistics, t-test, ANOVA, and Pearson's correlation coefficient using SPSS/WIN 20.0 program. Results: The mean emotional labor score was $3.4{\pm}0.60$. There was very strong and negative correlation between emotional labor and servant leadership (r=-.896, p<.001). Communication competence was positively correlated with servant leadership (r=.298, p<.001) and moderately and negatively correlated with both frequency of emotional labor (r=-.166, p=.016) and the degree of attention to emotional expression (r=-.143, p=.039). Conclusion: As a strategy to reduce emotional labor of hospital nurses, the findings suggest training programs for nurses to enhance servant leadership and communication competence.

SonicStream: A Network Coding Based Live P2P Media Streaming System With Rich User Experiences

  • Chen, Xiaogang;Ren, Ning;Zhang, Xiaochen;Wang, Xin;Zhao, Jin
    • Journal of Communications and Networks
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    • 제10권4호
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    • pp.430-436
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    • 2008
  • Recent studies have convinced that network coding can improve the performance of live media streaming in terms of startup delay, resilience to peer dynamics, as well as reduced bandwidth cost on dedicated streaming servers. However, there still exist some strategy drawbacks and neglected problems which need to be further researched. In addition to the commonly used evaluation parameters of the network and user experiences mentioned above, we focus on additional key factors, playback lag and switch lag, which have not been fully explored in previous work. In this paper, we present SonicStream, a novel and fully implemented live peer to peer (P2P) media streaming system with consideration of rich user experiences, including startup delay, playback continuity, playback lag, switch lag, etc. In pursuit of a further enhanced user experience, we revise traditional peer selection/data scheduling methods. Through a series of experimental evaluations and a cautious comparison with the latest similar work $R^2$, the superior performance of SonicStream has been preliminarily verified.

중년 성인의 신체활동과 대사증후군 지표의 관계 (The Association between Physical Activity and Metabolic Syndrome Index in Middle-aged Adults)

  • 방소연
    • Journal of Information Technology Applications and Management
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    • 제30권1호
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    • pp.71-80
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    • 2023
  • The purpose of this study is to promote understanding of physical activity and metabolic syndrome in middle-aged adults and to provide basic data of interventions development for the prevention and management of metabolic syndrome. Using the 2020 data for Korea National Health and Nutrition Examination Survey, 1,786 middle-aged adults between the ages of 40 and 64 with no missing data were analyzed. As a result of the study, 56.5(±2.1)% of men and 52.9(±1.81)% of women were sufficient activity group among physical activity, and the proportion of men was higher than that of women, but it was not statistically significant(t=1.27, p=.207). The prevalence of metabolic syndrome was 38.9(±2.1%) of men and 25.4(±1.5)% of women, the prevalence of men was significantly higher than that of women(t=5.12, p<.001). Compared to the insufficient activity group, the sufficient activity group had a 0.71(95% CI: 0.57~0.88) times the risk of developing low HDL(high density lipoprotein)- cholesterol(p=.002), and this pattern was maintained even after adjusting for age, education level, body mass index, smoking status, and drinking status(p=.002). Based on the results of this study, a physical activity and metabolic syndrome risk group in middle-aged adults should be selected, and physical activity promotion program to improve high density lipoprotein-cholesterol among metabolic syndrome indicators should be developed.

익산지역 강수성분의 연차적 변이 (Yearly Changes of Precipitation Component in the Iksan Area)

  • 이경보;이덕배;이상복;김재덕;박찬원
    • 한국환경농학회지
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    • 제25권1호
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    • pp.1-6
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    • 2006
  • 본 연구는 산성비의 대한 장기적이고 종합적인 대책방안을 마련하기 위한 기초 자료를 제공코자 1997년부터 2003년까지 7년 동안 산성강우 현상을 중심으로 조사하였다. 강수의 연차적 산성비 강하비율은 1997년 70.0%, 1998년 56.3%, 2003년 36.4%를 나타냈으나, 강우량이 적은 1999년부터 2002년의 산성비 강하비율은 $6.9{\sim}19.2%$를 보였다. 산성우에 대한 영향 평가시 단기간에 의한 것보다 장기적인 영향으로 발생하기 때문에 산성강하물의 농도뿐만 아니라 침착량의 해석이 필요하다. 강수중 주요 이온성분의 연평균 습성침착량은 각 이온성분의 당량농도에 강수량을 곱하여 산출하였다. 각 이온 성분의 침착량을 살펴보면 음이온은 ${SO_4}^{2-}>Cl^->{NO_3}^-$순이었으며, 양이온의 경우는 ${NH_4}^+>Ca^{2+}>Na^+>Mg^{2+}>K^+$순으로 많았다. 강수 중 주요성분에 대한 상관분석 결과 pH와 강수 이온 성분중 $Ca^{2+}$$Na^+$성분을 제외한 모든 성분에서 부의 상관을 나타냈으며 그 외 각 성분간의 상관은 정의 상관을 나타냈다. pH와 ${SO_4}^{2-}$간의 상관계수는 -0.508로 고도의 유의성을 나타냈는데 이는 ${SO_4}^{2-}$성분이 강수중 산성도를 증가시키는 주요원인 물질중 가장 큰 역할을 하고 있음을 추정할 수 있었다. 또한 ${SO_4}^{2-}$${NO_3}^-$ 이온은 $Ca^{2+},\;Mg^{2+},\;K^+,\;{NH_4}^+\;and\;Na^+$ 등 양이온과 고도의 유의성을 보였다.

중년여성 근로자의 자아탄력성과 감정노동이 직장-가정 갈등에 미치는 영향 (Effects of Ego-resilience and Emotional Labor on Work-family Conflict among Middle-aged Female Workers)

  • 전해옥;권유림
    • 한국산학기술학회논문지
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    • 제18권11호
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    • pp.187-196
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    • 2017
  • 본 연구의목적은 중년여성 근로자의 자아탄력성과 감정노동이 직장-가정 갈등에 미치는 영향을 파악하기 위함이다. 자료 수집은 A, B, C시에 소재한 직장에 근무하는 정규직과 비정규직에 종사자하는 중년여성 148명을 대상으로 2013년 10월 2일부터 2014년 4월 10일까지 자가 보고식 설문조사로 시행되었다. 연구결과, 중년여성의 직장-가정 갈등은 25.59(SD=11.99) 점으로, 대상자의 직장-가정 갈등은 거주유형(F=4.32, p=.015), 생활비 지출(r=.18, p=.028), 직업만족도(F=6.33, p<.001)에 따라 유의한 차이를 보였다. 직장-가정 갈등과 자아탄력성은 유의한 음의상관관계를 보였으며(r=-.28 p=.001), 부모, 자녀와 함께 사는 거주유형(${\beta}=.29$, p=.045), 생활비 지출(${\beta}=.22$, p=.006), 직업만족도(${\beta}=-.20$, p=.015), 자아탄력성(${\beta}=-.28$, p<.001)이 직장-가정 갈등에 유의한 영향을 주는 요인으로 약 19%의 설명력을 갖는 것으로 나타났다(F=6.61 p<.001). 그러므로 중년여성 근로자의 직장-가정 갈등의 수준을 감소하기 위한 전략으로, 직장-가정 갈등에 영향을 주는 거주유형 및 생활비 지출과 같은 사회경제적인 요인에 대한 고려가 필요하다. 또한 중년여성 근로자의 직업만족도 및 자아탄력성을 향상시킬 수 있는 직업 환경 내의 심리적인 중재의 적용이 중년여성의 직장-가정 갈등 감소에 도움이 될 것이다.