• Radiation Oncology Journal
• /
• v.34 no.3
• /
• pp.202-208
• /
• 2016

Purpose: Our institution has implemented two different adjuvant protocols in treating patients with non-small cell lung cancer (NSCLC): chemotherapy followed by concurrent chemoradiotherapy (CT-CCRT) and sequential postoperative radiotherapy (PORT) followed by postoperative chemotherapy (POCT). We aimed to compare the clinical outcomes between the two adjuvant protocols. Materials and Methods: From March 1997 to October 2012, 68 patients were treated with CT-CCRT (n = 25) and sequential PORT followed by POCT (RT-CT; n = 43). The CT-CCRT protocol consisted of 2 cycles of cisplatin-based POCT followed by PORT concurrently with 2 cycles of POCT. The RT-CT protocol consisted of PORT followed by 4 cycles of cisplatin-based POCT. PORT was administered using conventional fractionation with a dose of 50.4-60 Gy. We compared the outcomes between the two adjuvant protocols and analyzed the clinical factors affecting survivals. Results: Median follow-up time was 43.9 months (range, 3.2 to 74.0 months), and the 5-year overall survival (OS), locoregional recurrence-free survival (LRFS), and distant metastasis-free survival (DMFS) were 53.9%, 68.2%, and 51.0%, respectively. There were no significant differences in OS (p = 0.074), LRFS (p = 0.094), and DMFS (p = 0.490) between the two protocols. In multivariable analyses, adjuvant protocol remained as a significant prognostic factor for LRFS, favouring CT-CCRT (hazard ratio [HR] = 3.506, p = 0.046) over RT-CT, not for OS (HR = 0.647, p = 0.229). Conclusion: CT-CCRT protocol increased LRFS more than RT-CT protocol in patients with completely resected NSCLC, but not in OS. Further studies are warranted to evaluate the benefit of CCRT strategy compared with sequential strategy.

• Neonatal Medicine
• /
• v.28 no.3
• /
• pp.108-115
• /
• 2021

Purpose: Magnetic resonance imaging (MRI) is a useful tool for evaluating brain injury and maturation in preterm infants and often requires sedation to acquire images of sufficient quality. Infant sedation is often associated with adverse events, despite extreme precautions. In this study, the swaddling technique was investigated as an alternative non-pharmacological strategy to obtain brain MRIs of sufficient quality. Methods: We applied the feed and swaddle technique during routine brain MRI as a quality improvement project and compared its morbidity with that of sedation in a historic age-matched group. Seventy-nine very low birth weight infants in the neonatal intensive care unit of Ajou University Hospital (Suwon, Korea) were enrolled. Thirty-two (40.5%) infants were in the feed and swaddling group, and 47 (59.5%) were in the sedation group. Results: The morbidity associated with the cardiopulmonary system (swaddling group vs. sedation group: 53.13% [n=17] vs. 63.83% [n=30], P=0.723) and central nervous system (40.63% [n=13] vs. 29.79% [n=14], P=0.217) were not significantly different between groups. The MRI failure rate was not significantly different (swaddling group vs. sedation group: 12.5% [n=4] vs. 4.3% [n=2], P=0.174). The MRI scanning time was longer in the swaddling group than in the sedation group (76.5±20.3 minutes vs. 61.5±13.6 minutes, P=0.001). Cardiopulmonary adverse events were significantly less common in the swaddling group than in the sedation group (3.13% [n=1] vs. 34.04% [n=16], P=0.002). Conclusion: The success rate of MRI was comparable between the swaddling technique and sedation. Furthermore, despite the drawback of prolonged scan time, cardiopulmonary adverse events are fewer with swaddling than with sedative agents. Therefore, swaddling can be an alternative to sedation or anesthesia when performing neonatal MRI scans.

• Child Health Nursing Research
• /
• v.23 no.3
• /
• pp.312-318
• /
• 2017

Purpose: In this study factors affecting quality of life in mothers who have children with precocious puberty were identified. Methods: The participants were 102 mothers of children with precocious puberty. From September 12 to September 30, 2016, data were collected using a structured questionnaire and analyzed using SPSS/WIN 22.0. Results: Regression analysis showed that the model's explanatory power was 45%(F=28.71, p<.001). Role stress (t=-4.83, p<.001), objective burden (t=-2.71, p<.001), and average monthly income (t=4.12, p<.001) were factors affecting quality of life among these mothers. The most influential factor was role stress (${\beta}=-.41$), which showed a negative correlation. Conclusion: Role stress and objective burden were major factors that decreased the quality of life in these. The findings indicate that effective strategy programs for reducing role stress and objective burden are necessary to improve the quality of life in mothers of children with precocious puberty.

• Journal of Information Technology Applications and Management
• /
• v.26 no.4
• /
• pp.19-30
• /
• 2019

Many organizations need to comply with ISMS-P for information systems and personal information management for ISMS-P certification. Organizations should safeguard vulnerablities to information systems. However, as the kinds of information systems are diversified and the number of information systems increases, management of such vulnerabilities manually accompanies with many difficulties. SCAP is a protocol to manage the vulnerabilities of information system automatically with security standards. In this paper, for the introduction of SCAP in domestic domains we verify the applicability of server-oriented system which is one of ISMS-P certification targets. For SCAP applicability, For obtaining this goal, we analyze the structures and functions of SCAP. Then we propose schemes to check vulnerabilities of the server-oriented system. Finally, we implement the proposed schemes with SCAP to show the applicability of SCAP for verifying vulnerabilities of the server-oriented system.

• Journal of Digital Convergence
• /
• v.19 no.11
• /
• pp.373-379
• /
• 2021

This study intends to test the effects of blended learning and case based learning on learning strategies, critical thinking disposition and academic self-efficacy for undergraduate nursing students. A one group pre-post design was applied to adult nursing of 23 nursing students. Data were collected between March 2 and April 30, 2021. Data were analyzed by using SPSS/WIN 23.0. The results showed that learning strategies(t=-2.43, p=.019) and sub-factor cognitive strategy (t=-2.22, p=.031), meta cognitive strategy(t=-2.59, p=.013) and resource management strategy (z=-2.46, p=.014) were significantly higher than levels before blended learning and case based learning. Critical thinking disposition(t=-1.14, p=.262) and academic self-efficacy(t=-.34, p=.734) were higher than levels before but was no significantly. In conclusion, It was confirmed that blended learning and case based learning is an effective educational program that improves learning strategies of nursing students. In the future, it is necessary to develop a program in which blended learning and case based learning can improve critical thinking disposition and academic self-efficacy, and to verify the effectiveness.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.19 no.11
• /
• pp.614-625
• /
• 2018

This study was conducted to investigate the level of resilience and the factors affecting resilience in nursing students, and to provide basic data to develop a program that improves resilience of nursing students. Data were collected from 155 nursing students in D city from April 15 to May 30, 2018 using the Resilience Scale, College Life Stress Scale, Self-Efficacy Scale (SES), Multi-Dimensional Scale of Perceived Social Support (MSPSS), Positive Affect Scale, and Stress Coping Strategy Scale. Data were analyzed using t-tests, ANOVA, Pearson's correlation coefficient, and multiple regression. The mean score for resilience in nursing students was 3.54 points. There was a significant difference in resilience according to academic score and satisfaction with major. Resilience was significantly correlated with self-efficacy, social support, and active stress coping strategy. Factors that impacted resilience in multiple regression were self-efficacy (${\beta}=0.39$, p<0.001), active stress coping strategy (${\beta}=0.26$, p<0.001), and social support (${\beta}=0.16$, p<0.001). These factors explained 51.0% of the variance in the resilience of nursing students. Therefore, it will be necessary to develop a program that can enhance resilience by strengthening protective factors such as self-efficacy, active stress coping strategies, and social support.

• Research in Mathematical Education
• /
• v.25 no.4
• /
• pp.245-266
• /
• 2022

This study examines how teaching metacognitive strategies to students in a sixth-grade mathematics class affects their metacognitive awareness. Participants were 36 sixth-grade students in a middle school affiliated with the Ministry of National Education of Turkey in the 2020-2021 academic year. The students in the experimental group (n = 18) were taught a total of 40 mathematics lessons for eight weeks to improve their metacognitive awareness. The students in the control group (n=18) were taught mathematics in line with the regular mathematics curriculum. Using the Jr. Metacognitive Awareness Inventory, participants in both groups took a pre-test at the beginning and a post-test at the end of the study. To better interpret the data obtained, various statistical tests were performed. The pre-test and post-test averages of the groups were compared using the t-test for the normally distributed data for dependent and independent groups. The pre-test results showed no significant difference between the metacognitive awareness scores of the experimental and control groups (p>0.05). The comparison of post-test averages showed that students' metacognitive awareness differed significantly in favor of the experimental group (p<0.05). According to this, it was concluded that metacognitive strategy teaching in mathematics courses positively affected students' metacognitive awareness levels.

• The Transactions of the Korean Institute of Electrical Engineers P
• /
• v.65 no.4
• /
• pp.255-261
• /
• 2016

Korean Power System are operating a load shedding system to prevent voltage instability phenomenon caused by severe line contingencies. In order to apply the load shedding scheme should be selected a location, amount, delay time. Current load shedding system is load shedding amount that has been calculated in the steady-state analysis to load shed the total amount in first level, load shedding amount calculated in advance, it is possible to perform an unnecessary load shedding. In this paper, set a multi-level load shedding control strategy step-by-step selection of load shedding amount for the prevention of excessive load shedding. In addition, through a voltage resilience analysis of the power system by applying motor load ratio and sensitivity parameter to selection the multi level load shedding ratio and delay time. For this reason, to take advantage of the limit data of interchange power, by utilizing interface power flow data to set a multi-level load shedding control strategy for the stabilization of the Korean Power System.

• Toxicological Research
• /
• v.34 no.4
• /
• pp.297-302
• /
• 2018

Cells are constantly exposed to endogenous and exogenous chemical and physical agents that damage their genome by forming DNA lesions. These lesions interfere with the normal functions of DNA such as transcription and replication, and need to be either repaired or tolerated. DNA lesions are accurately removed via various repair pathways. In contrast, tolerance mechanisms do not remove lesions but only allow replication to proceed despite the presence of unrepaired lesions. Cells possess two major tolerance strategies, namely translesion synthesis (TLS), which is an error-prone strategy and an accurate strategy based on homologous recombination (homology-dependent gap repair [HDGR]). Thus, the mutation frequency reflects the relative extent to which the two tolerance pathways operate in vivo. In the present paper, we review the present understanding of the mechanisms of TLS and HDGR and propose a novel and comprehensive view of the way both strategies interact and are regulated in vivo.

• The Transactions of the Korean Institute of Electrical Engineers P
• /
• v.64 no.4
• /
• pp.251-255
• /
• 2015

Chiller system plays an important role of maintaining room temperature constantly by supplying chilled water to Heating, Ventilating and Air Conditioning(HVAC)or area room cooler equipment during plant normal operation or accident condition. Chiller failures are one of the most frequently occurring equipment failures. If the types of chiller failures are analyzed and grouped thoroughly, it would be helpful to make chiller maintenance strategy at the plants. That would enhance equipment reliability of chiller in the end. In this paper, chiller failure data during three years were analyzed and categorized by specific failure code. In addition, the various proposals to improve equipment reliability of chiller were suggested such as Preventive Maintenance Optimization(PMO) strategy and performance monitoring reinforcement and so on.