• Title/Summary/Keyword: 4P's strategies

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Risk Factors and Clinical Outcomes of Brain Reperfusion Injury after Mechanical Thrombectomy for Ischemic Stroke (기계적 혈전제거술을 시행한 허혈성 뇌졸중 환자의 뇌재관류 손상 위험요인과 임상결과)

  • Moon, Ji Hyun;Choi, Hye-Ran
    • Journal of Korean Biological Nursing Science
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    • v.23 no.3
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    • pp.217-226
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    • 2021
  • Purpose: The aim of this study was to investigate the risk factors for brain reperfusion injury in ischemic stroke patients and to analyze the clinical outcomes. Methods: A retrospective study was conducted in 168 patients who underwent mechanical thrombectomy. The data were analyzed using descriptive statistics, t-test, Mann-Whitney U test, Chi-Square test, Fisher's exact test, and logistic regression with IBM SPSS/WIN 24.0. Results: Brain reperfusion injury occurred in 67 patients (39.9%) with a low favored outcome (𝛘2=6.01, p=.014). On multivariable analysis, blood urea nitrogen (Odds ratio [OR]=1.14, 95% Confidence interval [CI]=1.06-1.23), aphasia (OR=6.16, CI=1.62-23.40), anosognosia (OR=4.84, CI=1.13-20.79), presence of both aphasia and anosognosia (OR=7.33, CI=1.20-44.60), and time required to achieve targeted blood pressure (OR=1.00, CI=1.00-1.00) were identified as risk factors for brain reperfusion injury. A statistically significant difference was detected in clinical outcomes, including hemorrhagic transformation (𝛘2=6.32, p=.012), intensive care unit length of stay (Z=-2.08, p=.038), National Institute of Health Stroke scale score at discharge (Z=-3.14, p=.002), and modified Rankin Scale score at discharge (Z=-2.93, p=.003). Conclusion: This study identified the risk factors and presented the clinical outcomes of brain reperfusion injury. It is necessary to consider these risk factors for evaluating the patients and to establish nursing interventions and strategies.

Factors Influencing Pain Intensity in Patients with Advanced Cancer (진행암 환자의 통증강도에 미치는 영향요인)

  • Lee, Sun-Hee;Chung, Bok-Yae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.1
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    • pp.506-516
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    • 2018
  • This study was conducted to identify pain intensity and factors affecting pain intensity in patients with advanced cancer. Data were collected between June 1 and September 30, 2016 using a questionnaire. The sample size was 221 patients with advanced cancer who were admitted to the oncology department or who visited the outpatient of the general hospital. Data were evaluated by descriptive and Pearson's correlation analyses, one way ANOVA, t-tests and stepwise multiple regression analysis. The mean scores of pain intensity of cancer patients were 4.23 (${\pm}1.68$) based on the average daily pain intensity. Factors influencing pain intensity were illness perception (${\beta}=.27$, p<.001), pain opioid analgesics beliefs (${\beta}=.24$, p<.001), education (middle school, ${\beta}=.24$, p=.001), economic status (${\geq_-}400$, ${\beta}=.20$, p=.001), gender (female, ${\beta}=.14$, p=.017), pain management education (${\beta}=-.14$ p=.020) and diagnosis (Pancreatic Ca, ${\beta}=.14$, p=.020). It explained 28%. Overall, the results of this study revealed that illness perception and pain opioid analgesics beliefs were important factors influencing pain intensity, but that the most important influencing factor was illness perception. Accordingly, it is necessary to develop pain management strategies that include not only pain management knowledge and pain opioid analgesics beliefs, but also illness perception.

The Influence of Growth Mindset and Professor Support on School Life Adjustment of Nursing College Freshman in the Era of COVID-19 (코로나19 시대 간호대학 신입생의 성장마인드셋과 교수지지가 학교생활적응에 미치는 영향)

  • Woo-Young Chae
    • Journal of the Korean Applied Science and Technology
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    • v.39 no.6
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    • pp.802-811
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    • 2022
  • The purpose of this study is to confirm the relationship between growth mindset, professor support and school life adjustment of nursing college freshman in the era of COVID-19, and to understand the effect on school life adjustment. The subjects of this study were 248 nursing college freshman located in G Metropolitan City, and data collection was conducted from October 4 to October 31, 2022. The collected data were analyzed by descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients and multiple regression analysis using the SPSS/WIN 28.0 program. As a result of the study, school life adjustment had a significant positive correlation with growth mindset(r=.51, p<.000) and professor support(r=.54, p<.000). Factors affectiong school life adjustment of nursing college freshman were professor support(β=.38, p<.001), subjects who answered very satisfied in major satisfaction(β=.31, p<.001), growth mindset(β=.26, p<.001), subjects who answered satisfied in major satisfaction(β=.16, p=.015), and female students(β=.14, p=.005), which explained 44.0% of variance. The results of this study will be usefully used to develop strategies to improve the school life adjustment of nursing college freshman. In the future, a follow-up study that can expand the subjects and explain the school life adjustment of nursing college freshman is suggested.

Shifts of Geographic Distribution of Pinus koraiensis Based on Climate Change Scenarios and GARP Model (GARP 모형과 기후변화 시나리오에 따른 잣나무의 지리적 분포 변화)

  • Chun, Jung Hwa;Lee, Chang Bae;Yoo, So Min
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.17 no.4
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    • pp.348-357
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    • 2015
  • The main purpose of this study is to understand the potential geographic distribution of P. koraiensis, which is known to be one of major economic tree species, based on the RCP (Representative Concentration Pathway) 8.5 scenarios and current geographic distribution from National Forest Inventory(NFI) data using ecological niche modeling. P. koraiensis abundance data extracted from NFI were utilized to estimate current geographic distribution. Also, GARP (Genetic Algorithm for Rule-set Production) model, one of the ecological niche models, was applied to estimate potential geographic distribution and to project future changes. Environmental explanatory variables showing Area Under Curve (AUC) value bigger than 0.6 were selected and constructed into the final model by running the model for each of the 27 variables. The results of the model validation which was performed based on confusion matrix statistics, showed quite high suitability. Currently P. koraiensis is distributed widely from 300m to 1,200m in altitude and from south to north as a result of national greening project in 1970s although major populations are found in elevated and northern area. The results of this study were successful in showing the current distribution of P. koraiensis and projecting their future changes. Future model for P. koraiensis suggest large areas predicted under current climate conditions may be contracted by 2090s showing dramatic habitat loss. Considering the increasing status of atmospheric $CO_2$ and air temperature in Korea, P. koraiensis seems to experience the significant decrease of potential distribution range in the future. The final model in this study may be used to identify climate change impacts on distribution of P. koraiensis in Korea, and a deeper understanding of its correlation may be helpful when planning afforestation strategies.

Risk Factors for Early and Late Intrahepatic Recurrence in Patients with Single Hepatocellular Carcinoma Without Macrovascular Invasion after Curative Resection

  • Li, Shu-Hong;Guo, Zhi-Xing;Xiao, Cheng-Zuo;Wei, Wei;Shi, Ming;Chen, Zhi-Yuan;Cai, Mu-Yan;Zheng, Lie;Guo, Rong-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4759-4763
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    • 2013
  • Background: Prognostic factors of postoperative early and late recurrence in patients with hepatocellular carcinoma (HCC) undergoing curative resection remain to be clarified. The aim of this study was to identify risk factors for postoperative early (${\leq}$ 2 year) and late (> 2 year) intrahepatic recurrences in patients with single HCCs without macrovascular invasion. Methods: A total of 280 patients from December 2004 to December 2007 were retrospectively included in this study. Intrahepatic recurrence was classified into early (${\leq}$ 2 year) and late (> 2 year) and the Chi-Square test or Fisher's exact test and multivariate logistic regression analysis were performed to determine significant risk factors. Results: During the follow-up, 124 patients had intrahepatic recurrence, early and late in 82 and 42 patients, respectively. Multivariate logistic regression analysis showed that microvascular invasion (p=0.006, HR: 2.397, 95% CI: 1.290-4.451) was the only independent risk factor for early recurrence, while being female (p = 0.031, HR: 0.326, 95% CI: 0.118-0.901), and having a high degree of cirrhosis (P=0.001, HR: 2.483, 95% CI: 1.417-4.349) were independent risk factors for late recurrence. Conclusions: Early and late recurrence of HCC is linked to different risk factors in patients with single HCC without macrovascular invasion. This results suggested different emphases of strategies for prevent of recurrence after curative resection, more active intervention including adjuvant therapy, anti-cirrhosis drugs and careful follow-up being necessary for patients with relevant risk factors.

The genetically healthy terrestrial orchid Liparis krameri on southern Korean Peninsula

  • CHUNG, Mi Yoon;CHUNG, Jae Min;SON, Sungwon;MAO, Kangshan;LOPEZ-PUJOL, Jordi;CHUNG, Myong Gi
    • Korean Journal of Plant Taxonomy
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    • v.49 no.4
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    • pp.324-333
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    • 2019
  • Neutral genetic diversity found in plant species usually leaves an indelible footprint of historical events. Korea's main mountain range (referred to as the Baekdudaegan [BDDG]), is known to have served as a glacial refugium primarily for the boreal and temperate flora of northeastern Asia. In addition, life-history traits (life forms, geographic range, and breeding systems) influence the within- and among-population genetic diversity of seed plant species. For example, selfing species harbor significantly less within-population genetic variation than that of predominantly outcrossers. A previous study of two Liparis species (L. makinoana and L. kumokiri) emphasizes the role of the abovementioned factors shaping the levels of genetic diversity. Liparis makinoana, mainly occurring on the BDDG and self-incompatible, harbors high levels of within-population genetic diversity (expected heterozygosity, HeP = 0.319), whereas there is no allozyme variation (HeP = 0.000) in L. kumokiri, which is self-compatible and mainly occurs in lowland hilly areas. To determine if this trend is also found in other congeners, we sampled five populations of L. krameri from the southern part of the Korean Peninsula and investigated the allozyme-based genetic diversity at 15 putative loci. The somewhat intermediate levels of within-population genetic variation (HeP = 0.145) found in L. krameri are most likely due to its occurrence in mountainous areas that, despite being outside of the main ridge of the BDDG, still served as refugia, and a self-incompatible breeding system. Management strategies are suggested for L. krameri and L. makinoana based on the levels and distribution of genetic diversity and inbreeding.

Dietary composition of two coexisting bat species, Myotis ikonnikovi and Plecotus ognevi, in the Mt. Jumbong forests, South Korea

  • Sungbae Joo;Injung An;Sun-Sook Kim
    • Journal of Ecology and Environment
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    • v.47 no.4
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    • pp.168-176
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    • 2023
  • Background: Many insectivorous bats have flexible diets, and the difference in prey item consumption among species is one of the key mechanisms that allows for the avoidance of interspecies competition and promotes coexistence within a microhabitat. In Korea, of the 24 bat species that are known to be distributed, eight insectivorous bats use forest areas as both roosting and foraging sites. Here, we aimed to understand the resource partitioning and coexistence strategies between two bat species, Myotis ikonnikovi and Plecotus ognevi, cohabiting the Mt. Jumbong forests, by comparing the differences in dietary consumption based on habitat utilization. Results: Upon examining their dietary composition using the DNA meta-barcoding approach, we identified 403 prey items (amplicon sequence variants). A greater prey diversity including Lepidoptera, Diptera, Coleoptera, and Ephemeroptera, was detected from M. ikonnikovi, whereas most prey items identified from P. ognevi belonged to Lepidoptera. The diversity index of prey items was higher for M. ikonnikovi (H': 5.67, D: 0.995) than that for P. ognevi (H': 4.31, D: 0.985). Pianka's index value was 0.207, indicating little overlap in the dietary composition of these bat species. Our results suggest that M. ikonnikovi has a wider diet composition than P. ognevi. Conclusions: Based on the dietary analysis results, our results suggests the possibility of differences in foraging site preferences or microhabitat utilization between two bat species cohabiting the Mt. Jumbong. In addition, these differences may represent one of the important mechanism in reducing interspecific competition and enabling coexistence between the two bat species. We expected that our results will be valuable for understanding resource partitioning and the coexistence of bats inhabiting the Korean forests.

A Study on Nursing Needs of Patients in the Recovery Room (회복실 환자의 간호요구도에 관한 연구 - 일 종합병원을 중심으로 -)

  • Kim Eun-Kyoung;Chae Soon-Ok;Kwon Kun-Sook;Kim Yun-Jeung;Hong Mun-He;Kim Me-Hee;Kim Nam-Sun;Lee Kyu-Eun
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.9 no.1
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    • pp.86-100
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    • 2002
  • Purpose: The purpose of the study was done to identify the nursing care needs of patients in the recovery room. Method: The subjects in this study were 127 patients in a recovery room between 6/9/2001 and 24/9/2001. The instrument used for this study was the descriptive questionnaire developed by Shin Hyun-Jin (1999). The data was analysed by frequency, percentage, mean, standard deviation, t-test, ANOVA, and factor analysis using the SPSS program. Result: 1) Kaiser - Meyer -O1kin sample appropriateness was 799 and Bartlett's test of sphericity significant probability was .000. 2) The mean score for nursing care need of patients in the recovery room was $4.17{\pm}.51$ of a total possible score of 5. The score of nursing need for different parameters was as follows : Educational need ($4.31{\pm}.49$), physical need ($4.27{\pm}.47$), emotional need ($4.11{\pm}.52$), environmental need ($3.99{\pm}.56$). 3) Differences in the needs for nursing care according to the demographics were significant for gender, marital status, operation experience, and departments consulted. General characteristic variables significantly related to nursing need were as follows: Physical need significantly related to the departments consulted (F=2.23, p=.036). Educational need significantly related to the marital status (F=2.55. p=.012), departments consulted (F=2.30, p= 031). Emotional need significantly related to the marital status (F=2.22, p=.028). Environmental need significantly related to the gender (t=-2.44, p= .016), marital status (F=2.01, p= .046). operation experience (t=-1.99. p= .048). Conclusion: Nursing care needs of patients in the recovery room are significantly related to educational need, physical need, emotional need and environmental need. Intervention plans and program need to be developed to improve strategies to meet nursing needs of patients in the recovery room.

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Production of Methanol from Methane by Encapsulated Methylosinus sporium

  • Patel, Sanjay K.S.;Jeong, Jae-Hoon;Mehariya, Sanjeet;Otari, Sachin V.;Madan, Bharat;Haw, Jung Rim;Lee, Jung-Kul;Zhang, Liaoyuan;Kim, In-Won
    • Journal of Microbiology and Biotechnology
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    • v.26 no.12
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    • pp.2098-2105
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    • 2016
  • Massive reserves of methane ($CH_4$) remain unexplored as a feedstock for the production of liquid fuels and chemicals, mainly because of the lack of economically suitable and sustainable strategies for selective oxidation of $CH_4$ to methanol. The present study demonstrates the bioconversion of $CH_4$ to methanol mediated by Type I methanotrophs, such as Methylomicrobium album and Methylomicrobium alcaliphilum. Furthermore, immobilization of a Type II methanotroph, Methylosinus sporium, was carried out using different encapsulation methods, employing sodium-alginate (Na-alginate) and silica gel. The encapsulated cells demonstrated higher stability for methanol production. The optimal pH, temperature, and agitation rate were determined to be pH 7.0, $30^{\circ}C$, and 175 rpm, respectively, using inoculum (1.5 mg of dry cell mass/ml) and 20% of $CH_4$ as a feed. Under these conditions, maximum methanol production (3.43 and 3.73 mM) by the encapsulated cells was recorded. Even after six cycles of reuse, the Na-alginate and silica gel encapsulated cells retained 61.8% and 51.6% of their initial efficiency for methanol production, respectively, in comparison with the efficiency of 11.5% observed in the case of free cells. These results suggest that encapsulation of methanotrophs is a promising approach to improve the stability of methanol production.

Acid Resistance of Non-O157 Shiga Toxin-Producing Escherichia coli Adapted in Fruit Juices in Simulated Gastric Fluid (위합성용액에서 과일주스에 노출한 Non-O157 Shiga Toxin-Producing Escherichia coli의 산 저항성 평가)

  • Kim, Gwang-Hee;Oh, Deog-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.45 no.4
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    • pp.577-584
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    • 2016
  • The objectives of this study were I) to compare the acid resistance (AR) of seven non-O157 Shiga toxin-producing Escherichia coli (STEC) serogroups, including O26, O45, O103, O111, O121, O145, and O157:H7 STEC isolated from various sources, in 400 mM acetic acid solution (AAS) at pH 3.2 and $30^{\circ}C$ for 25 min with or without glutamic acid and II) to determine strain survival upon exposure to simulated gastric fluid (SGF, pH 1.5) at $37^{\circ}C$ for 2 h after acid adaptation in apple, pineapple, orange, and strawberry juices at pH 3.8, $4^{\circ}C$ and $20^{\circ}C$. Results show that the O111 serogroup strains had the strongest AR (0.12 log reduction CFU/mL) which was very similar to that of O157:H7 STEC (P>0.05), compared to other serogroups in AAS without glutamic acid, whereas O26 serogroup strains showed the most sensitive AR. However, there was no significant (P>0.05) difference of AR among seven serogroups in AAS with glutamic acid. In the SGF study, 05-6545 (O45:H2), 08023 (O121:H19), and 03-4669 (O145:NM) strains adapted in fruit juices at $4^{\circ}C$ and $20^{\circ}C$ displayed enhanced survival with exposure to SGF for 60 min compared to 06E0218 (O157:H7) strains (P<0.05). In addition, 4 STEC strains adapted in pineapple juice at $4^{\circ}C$ showed enhanced survival with exposure to SGF for 60 min compared to those strains acid-adapted in the other fruit juices. Generally, adaptation at $4^{\circ}C$ in fruit juices resulted in significantly enhanced survival levels compared to acid-adapted at $20^{\circ}C$ and non-adapted conditions. The AR caused by adaptation in fruit juices at low temperature may thus increase survival of non-O157 STEC strain in acidic environments such as the gastrointestinal tract. These results suggest that more careful strategies should be provided to protect against risk of foodborne illness by non-O157 STEC.