• Journal of Chest Surgery
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• v.30 no.9
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• pp.899-907
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• 1997

Recently, primary lung cancer has increased markedly in incidence & prevalence in korea. Prom July 1979 to June 1996, 183 patients were diagnosed and operated for primary non-small cell lung cancer, and evaluated clinically. 1. There were 164 males and 19 females(M:P=8.6: 1), and the peak incidence of age was 50th and 60th decade of life(73.7%). 2. Most of symptoms were respiratory, whitch were cough(44.8%), chest pain(30.1%), dyspnea(20.8%), hemoptysis or blood tinged sputum(19.7%), sputum(15.3%), and asymptomatic cases were 12.0%. 3. Histopathologically, sguamous cell carcinoma was 68.9%, adenocarcinoma 19.7%, bronchioloalveol r cell carcinoma 2.2%, adenosguamous cell carcinoma 1.6%, and large cell carcinoma 7.7%. 4. In the operation, pneumonectomy was 41.0%, lobectomy 42.1%, bilobectomy 13.1%, stagmentectomy or wedge resection 1.6%, and explore tharacotomy 2.2%, and the overall resectability was 97.8%. 5. Postoperative complications were developed in 31.9%, and operative mortality was 1.6%. 6. In postoperative stagings, stage I was 38.3%, stage H 14.8%, stage llla 31.1%, and stage IIIb 15.8%. 7. The overall cumulative survival rates were 1 year 77.8%, 3 year 42.7%, and 5 year 39.5%. The 5 year survival rate according to stage were stage 153.0%, stage H 46.5%, stage I[la 28.2%, and stage IIIb 13.8%(p<0.05), according to operation method were lobectomy 45.0%, and pneumonectomy 30.3%(p<0.05), and according to mediastinal involvement were Nl 32.0%, and N2 11.1%(p<0.05). The 5 year survival rate according to histologic type were squamous cell carcinoma 43.1%, adenocarcinoma 23.3%, and large cell carcinoma 30.3 (p>0.05).

• Journal of Korea Port Economic Association
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• v.24 no.4
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• pp.71-96
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• 2008

The purpose of this study is to suggest the new strategies for West coast ports, especially Mokpo Port development. This paper also analyzes the recently evolving change of shipping environment such as upsizing of vessels, horizontal and vertical integration strategies in the liner shipping industries through the mergers and acquisitions or strategic alliances, establishment of dedicated terminal and surging bunker charge. With shipping environment is rapidly changing, we examine how to cope with the current situation and suggest the solutions how to tackle shippers' and shipping companies' request. As a result of an empirical study, we found out that Mokpo Port suffers from the shortage of container cargo, container imbalance, insufficient forwarders and inland trucking service providers and hinterland transportation network system. With these obstacles settled, the number of container cargo can be induced to Mokpo Port and the regular container services between Mokpo and Chinese ports and Japanese ports loops were found to be competitive.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.7
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• pp.1044-1052
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• 2015

The aim of this modelling study was to investigate the effect of large herd size (and land areas) on walking distances and milking interval (MI), and their impact on milk yield and economic penalties when 50% of the total diets were provided from home grown feed either as pasture or grazeable complementary forage rotation (CFR) in an automatic milking system (AMS). Twelve scenarios consisting of 3 AMS herds (400, 600, 800 cows), 2 levels of pasture utilisation (current AMS utilisation of 15.0 t dry matter [DM]/ha, termed as 'moderate'; optimum pasture utilisation of 19.7 t DM/ha, termed as 'high') and 2 rates of incorporation of grazeable complementary forage system (CFS: 0, 30%; CFS = 65% farm is CFR and 35% of farm is pasture) were investigated. Walking distances, energy loss due to walking, MI, reduction in milk yield and income loss were calculated for each treatment based on information available in the literature. With moderate pasture utilisation and 0% CFR, increasing the herd size from 400 to 800 cows resulted in an increase in total walking distances between the parlour and the paddock from 3.5 to 6.3 km. Consequently, MI increased from 15.2 to 16.4 h with increased herd size from 400 to 800 cows. High pasture utilisation (allowing for an increased stocking density) reduced the total walking distances up to 1 km, thus reduced the MI by up to 0.5 h compared to the moderate pasture, 800 cow herd combination. The high pasture utilisation combined with 30% of the farm in CFR in the farm reduced the total walking distances by up to 1.7 km and MI by up to 0.8 h compared to the moderate pasture and 800 cow herd combination. For moderate pasture utilisation, increasing the herd size from 400 to 800 cows resulted in more dramatic milk yield penalty as yield increasing from c.f. 2.6 and 5.1 kg/cow/d respectively, which incurred a loss of up to $AU 1.9/cow/d. Milk yield losses of 0.61 kg and 0.25 kg for every km increase in total walking distance (voluntary return trip from parlour to paddock) and every one hour increase in MI, respectively. The high pasture utilisation combined with 30% of the farm in CFR in the farm increased milk yield by up to 1.5 kg/cow/d, thereby reducing loss by up to $0.5/cow/d (c.f. the moderate pasture and 800 cow herd scenario). Thus, it was concluded that the successful integration of grazeable CFS with pasture has the potential to improve financial performance compared to the pasture only, large herd, AMS.

• Asian-Australasian Journal of Animal Sciences
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• v.25 no.5
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• pp.708-716
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• 2012

In order to investigate and evaluate the effects of red deer antlers on hair growth in the full-thickness wound healing model, Sprague-Dawley rats were given incision wounds through the full thickness of their dorsal skin and deer antler was applied for 40 days. At specified intervals thereafter (4, 8, 16, 32 and 40 days), the animals were sacrificed and the wound site skins were excised, processed, and sectioned. At post-injury days 16, 32 and 40, longer and more active new hair appeared around the healing wound of antler-treated skin. Histological studies showed that the antler extract markedly increases the depth, size, and number of hair follicles. Expression of IGF-I (insulin-like growth factor) mRNA was detected by RT-PCR and real time RT-PCR. The result showed that the expression of IGF-I (days 16, 32, and 40) was obviously up-regulated in antler-treated skins compared to control skins. Similar results were seen in the ELISA analysis to quantify the IGF-I expression. These results support the notion that wound healing can cause hair growth by enhancing the expression of IGF-I. Deer antler extract appears to have the potential to promote hair growth and could be used in hair growth products.

• International Journal of Highway Engineering
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• v.7 no.4 s.26
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• pp.163-171
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• 2005

Current roads were designed and constructed based on the design criteria and thus those were overly simplified drivers' needs. The road criteria do not suggest the desirable range of the design values but suggest the minimum requirements for the road design. Therefore, a completed road design based on the design criteria does not always guarantee the best design in terms of safety and it sometimes violates drivers' expectation. Therefore, the ROSSAV(ROad Safety Survey and Analysis Vehicle) is being developed by the KICT to evaluate road safety and increase driving safety. In this paper, the image capture system was described in detail. The image capture system is consisted of two front view cameras, two side down-looking cameras and a synchronization device. Two front view cameras were used to take a picture of road and road facilities at the driver's viewpoint. Also, two side down-looking cameras were used to capture road surface image to extract lane markings. A synchronization device were used to generate image capturing signal at the fixed distance spacing huck as every 10m. The front view images could be used to calculate and measure highway geometry such as shoulder width because every image is saved with it's locational information. And also the side down looking images could be used to extract median lane mark which representing road alignement efficiently.

• The Korean Journal of Mycology
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• v.26 no.4 s.87
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• pp.450-457
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• 1998

The cryparin of Cryphonectria parasitica belongs to a cell wall associated fungal hydrophobin. The cryparin, though it is encoded by a single copy gene, is known for the high expression during the liquid culture of C. parasitica, and it turns out that 22% of total mRNA was transcribed for cryparin at 48hr after the liquid culture. In addition, it is also known as one of down-regulated fungal proteins by the presence of double stranded RNA virus, Cryphonectria hypovirus 1. In previous studies (Kim et al., 1999), we have constructed a cryparin-null mutant by replacing the cryparin gene with hygromycin B resistance gene due to site directed homologous recombination. In order for the promoter analysis of cryparin which seems to be very strong as well as mycoviral specific, it is preferable to have a strain with only a target promoter replaced and a discernable target site for incoming vectors. However, the cryparin-null mutant revealed the presence of an additional copy of transforming vector except the one which replaced the cryparin gene. In addition, the cryparin-null mutant did not contain any markers for targeted integration of incoming vectors. This prompts us to design an experiment to obtain a strain for promoter analysis of cryparin gene. A different mating type strain EP6(Mata, $met^-$) was mated with the cryparin-null mutant ${\triangle}$Crp194-7(MatA, Crp${\triangle}$::hph) to make the progenies with only a single replacement vector and $met^-$ characteristic remained. Nutritional assay as well as Southern blot analysis revealed that the progeny, ${\triangle}$Crp194-a6, was the methionine auxotroph with a single replacing vector in genome. Northern blot analysis and PAGE showed that there was no cryparin produced in this bred strain either.

• Proceedings of the KOR-KST Conference
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• 1998.10a
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• pp.151-160
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• 1998

실시간 교통정보 처리과정은 현장설비로부터 수집되는 각종 교통상황자료를 분석/처리하여 소통상황, 주행속도, 통행시간 등의 교통상황을 단기 예측하는 과정으로서 이는 주행안내시스템의 핵심요소기술이다. 주행안내 시스템 개발의 필요성은 선진국을 중심으로 제기되어 왔으며, 주행안내시스템은 각국 정부의 강력한 지원정책을 바탕으로 연구개발 단계를 거쳐 시범운영의 단계에 있다. 국내에서도 교통정체의 해소와 안전주행의 연구개발 단계를 거쳐 시범운영의 단계에 있다. 국내에서도 교통정체의 해소와 안전주행의 여건마련을 위하여 교통정보를·처리·제공하는 기술의 개발이 활발하게 진행되고 있다. 그러나 국내 기술수준을 보면 전자통신기술을 바탕으로 교통정보의 수집과 제공에 관한 연구는 어느 정도 진행되고 있으나 운전자가 필요로 하는 교통정보의 분석과 처리에 관한 연구는 매우 저조한 실정이다. 본 연구의 목적은 다양한 시스템에서 수집되는 자료를 종합적으로 처리, 저장,관리하고 이의 분석결과를 제공하는 교통정보센터의 프로토타입(Prototype)을 설정하는 것이다. 이러한 목표를 수행하기 위해서 요구되는 교통정보실험실의 기능은 수집된 교통자료의 신뢰성 분석, 교통정보의 종합적인 처리·저장·관리, 그리고 교통정보의 제공은 구분할 수 있다. 따라서, 현재 교통정보실험실에서 운영중인 정보의 형태를 제시하며, 이들 정보의 신뢰성을 실측자료와 비교한 실험적 결과를 예시한다. 또한, 개별 정보이용자에게 실시간 교통정보를 제공하기 위한 통신기술의 검토가 이루어진다. 차내 이용자에게 정보를 실시간으로 제공하기 위해서는 궁극적으로 무선통신기술의 응용이 필요하며, 정보이용자에게 다양한 정보를 제공하기 위해서 인터넷 통신과 연계시키는 것이 합리적으로 판단된다. 결론 부분에서는 교통정보실험실의 기능을 강화시키기 위한 향후의 연구과제를 제시한다.Si결정의 크기를 비교하였을 때 45$\mu\textrm{m}$ 이하의 분말을 섞어 압출하였을 때 가장 작은 초정 Si입자 크기를 얻음 을 볼 수 있었다. 주의 Fairfax County에 소재한 주간 고속도로 66번(I-66)과 인접 교통망의 교통자료를 사용하여 각종 돌발교통 혼잡 상황을 전제로 한 Traffic Simulation과 정보제공시나\리오를 INTEGRATION Model을 이용해 실행하였다. 그 결과 적응형 알고리즘이 개개인의 최단시간 경로를 제공하는 사용자 평형 경로안내전략에 비해 교통혼잡도와 정체시간의 체류정도에 따라 3%에서 10%까지 전체통행시간을 절약할 수 있다는 결론을 얻었다.출발참, 구성대외개방선면축심, 실현국제항선적함접화국내항반적전항, 형성다축심복사식항선망; 가강기장건설, 개피포동제이국제기장건설, 괄응포동개발경제발전적수요. 부화개시일은 각 5월 26일과 5월 22일이었다. 11. 6월 중순에 애벌레를 대상으로 처리한 Phenthoate EC가 96.38%의 방제가로 약효가 가장 우수하였고 3월중순 및 4월중순 월동후 암컷을 대상으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was resulted from increase of weight of single cocoon. "Manta"2.5ppm produced 22.2kg of cocoon. It is equal to 9% increase in index, as com

• Proceedings of the KOR-KST Conference
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• 1998.10b
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• pp.191-191
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• 1998

ITS를 구성하는 서비스나 기능이 대부분 동적인 특성을 지니고 있어, 앞으로는 이를 효율적으로 뒷받침할 수 있는 공간데이터(Spatial Data)가 필요하다. 특히, 대부분의 ITS서비스와 기능이 정보의 신속한 전달을 위해서 유무선통신을 사용할 것이다. 또한, 최정 사용자서비스와 응용분야가 공간데이터라는 기본적인 정보를 공유하므로써 위치에 대한 정적·동적교통정보를 제공받게 된다. 정보사용자가 사용하는 공간데이터가 상이하다면, 정보의 공유가 이루어지지 않거나 정확하게 제공되지 않는 것은 자명한 사실이다. 이러한 이유는 정보사용자가 자신들의 정보수집, 정보전달, 정보분석 등의 목적에 적합한 공간데이터를 제작하여 유지하기 때문이다. 결과적으로 정보의 공유를 위해서는 상이한 공간데이터들 간에 동일한 교통정보를 공유하도록 하는 조작이나 방법이 필요하다. 서로 다른 원본으로 구성된 데이터를 통합하고 이를 ITS서비스와 기능을 위한 각 시스템에 적용하기 위해서는 서로 다른 수준을 가지고 있는 공간데이터(수치지도 데이터)의 해상도, 위치정확도, 속성정확도, 정밀도, 범위 등과 같은 문제들이 최종 응용시스템에 적용되어져야 하고, 이를 통해 공간적인 위치와 수치지도를 구성하는 각종 엔터티가 참조되어야 할 것이다. 이뿐 아니라, 향후 데이터 공유의 방법에 있어서도, 각종 무선통신의 발달과 인터넷과 같은 정보전달매체의 대중화가 이루어짐에 따라, 정보의 공유가 동시적으로 이루어질 것이다. 본 연구에서는 공공기관주도로 제작된 전국범위의 수치지도를 하여, ITS용 네트워크데이터구성을 위한 기능분석과 사양을 제시를 함으로써, 이에 대한 프로파일 개발한다. 정보공유를 위한 위치참조모델(LRM)과 프로파일을 ITS데이터에 적용함으로써, 위치참조모델의 기능과 적용성을 평가한다.키기 위한 향후의 연구과제를 제시한다.Si결정의 크기를 비교하였을 때 45$\mu\textrm{m}$ 이하의 분말을 섞어 압출하였을 때 가장 작은 초정 Si입자 크기를 얻음 을 볼 수 있었다. 주의 Fairfax County에 소재한 주간 고속도로 66번(I-66)과 인접 교통망의 교통자료를 사용하여 각종 돌발교통 혼잡 상황을 전제로 한 Traffic Simulation과 정보제공시나\리오를 INTEGRATION Model을 이용해 실행하였다. 그 결과 적응형 알고리즘이 개개인의 최단시간 경로를 제공하는 사용자 평형 경로안내전략에 비해 교통혼잡도와 정체시간의 체류정도에 따라 3%에서 10%까지 전체통행시간을 절약할 수 있다는 결론을 얻었다.출발참, 구성대외개방선면축심, 실현국제항선적함접화국내항반적전항, 형성다축심복사식항선망; 가강기장건설, 개피포동제이국제기장건설, 괄응포동개발경제발전적수요. 부화개시일은 각 5월 26일과 5월 22일이었다. 11. 6월 중순에 애벌레를 대상으로 처리한 Phenthoate EC가 96.38%의 방제가로 약효가 가장 우수하였고 3월중순 및 4월중순 월동후 암컷을 대상으로 처리한 Machine oil, Phenthoate EC 및 Trichlorfon WP는 비교적 약효가 낮았다.>$^{\circ}$E/$\leq$30$^{\circ}$NW 단열군이 연구지역 내에서 지하수 유동성이 가장 높은 단열군으로 추정된다. 이러한 사실은 3개 시추공을 대상으로 실시한 시추공 내 물리검층과 정압주입시험에서도 확인된다.. It was resulted from increase of weight of single cocoon. "Manta"2.5ppm produced 22.2kg of cocoon. It

• Journal of Internet Computing and Services
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• v.20 no.6
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• pp.129-135
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• 2019

Recently, studies have been conducted to improve the m-commerce process in the NFC-based mobile environment and the increase of the number of smart phones built in NFC. Since authentication is important in mobile electronic payment, FIDO(Fast IDentity Online) and 2 Factor electronic payment system are applied. In addition, block-chains using distributed raw materials have emerged as a representative technology of the fourth industry. In this study, for the mobile gallery auction of the traders using NFC embedded terminal (smartphone) in a small gallery auction in which an unspecified minority participates, password-based authentication and biometric authentication technology (fingerprint) were applied to record transaction details and ownership transfer of the auction participants in electronic payment. And, for the cost reduction and data integrity related to gallery auction, the private distributed director block chain was constructed and used. In addition, domestic and foreign cases applying block chain in the auction field were investigated and compared. In the future, the study will also study the implementation of block chain networks and smart contract and the integration of block chain and artificial intelligence to apply the proposed method.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2010.10a
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• pp.14-14
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• 2010

Vitamin C (ascorbic acid) is an essential component for collagen biosynthesis and also for the proper functioning of the cardiovascular system in humans. Unlike most of the animals, humans lack the ability to synthesize ascorbic acid on their own due to a mutation in the gene encoding the last enzyme of ascorbate biosynthesis. As a result, vitamin C must be obtained from dietary sources like plants. In this study, we have developed two different kinds of transgenic potato plants (Solanumtuberosum L. cv. Taedong Valley) overexpressing strawberry GalUR and mouse GLoase gene under the control of CaMV 35S promoter with increased ascorbic acid levels. Integration of the these genes in the plant genome was confirmed by PCR and Southern blotting. Ascorbic acid(AsA) levels in transgenic tubers were determined by high-performance liquid chromatography(HPLC). The over-expression of these genes resulted in 2-4 folds increase in AsA intransgenic potato and the levels of AsA were positively correlated with increased geneactivity. The transgenic lines with enhanced vitamin C content showed enhanced tolerance to abiotic stresses induced by methyl viologen(MV), NaCl or mannitol as compared to untransformed control plants. The leaf disc senescence assay showed better tolerance in transgenic lines by retaining higher chlorophyll as compared to the untransformed control plants. Present study demonstrated that the over-expression of these gene enhanced the level of AsA in potato tubers and these transgenics performed better under different abiotic stresses as compared to untransformed control. We have also investigated the mechanism of the abiotic stress tolerance upon enhancing the level of the ascorbate in transgenic potato. The transgenic potato plants overexpressing GalUR gene with enhanced accumulation of ascorbate were investigated to analyze the antioxidants activity of enzymes involved in the ascorbate-glutathione cycle and their tolerance mechanism against different abiotic stresses under invitro conditions. Transformed potato tubers subjected to various abiotic stresses induced by methyl viologen, sodium chloride and zinc chloride showed significant increase in the activities of superoxide dismutase(SOD, EC 1.15.1.1), catalase, enzymes of ascorbate-glutathione cycle enzymes such as ascorbate peroxidase(APX, EC 1.11.1.11), dehydroascorbate reductase(DHAR, EC 1.8.5.1), and glutathione reductase(GR, EC 1.8.1.7) as well as the levels of ascorbate, GSH and proline when compared to the untransformed tubers. The increased enzyme activities correlated with their mRNA transcript accumulation in the stressed transgenic tubers. Pronounced differences in redox status were also observed in stressed transgenic potato tubers that showed more tolerance to abiotic stresses when compared to untransformed tubers. From the present study, it is evident that improved to lerance against abiotic stresses in transgenic tubers is due to the increased activity of enzymes involved in the antioxidant system together with enhanced ascorbate accumulated in transformed tubers when compared to untransformed tubers. At moment we also investigating the role of enhanced reduced glutathione level for the maintenance of the methylglyoxal level as it is evident that methylglyoxal is a potent cytotoxic compound produced under the abiotic stress and the maintenance of the methylglyoxal level is important to survive the plant under stress conditions.