• Title/Summary/Keyword: 4D Planning

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Effect of CT Contrast Media on Radiation Therapy Planning (Head & Neck Cancer and Prostate Cancer) (CT조영제가 방사선치료계획(두경부, 전립선)에 미치는 영향)

  • Jang, Jaeuk;Han, Manseok;Kim, Minjeong;Kang, Hyeonsoo
    • Journal of the Korean Magnetics Society
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    • v.26 no.5
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    • pp.173-178
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    • 2016
  • This study is to evaluate the effect of a Contrast Media (CM) on dose calculations and clinical significance in Radiation (Electromagnetic wave) Therapy (RT) plans for head & neck (H&N) and prostate cancer. Pinnacle 8.0 system was used to measure the change of Electron Density (ED) of the tissue for CM. To determine the effect of dose calculation due to CM, we did the RT planning for 30 patients. To compare the ED and dose calculations of RT plans, 3D CRT and IMRT plans were do with pinnacle and Tomotherapy planning system. Mean difference of ED between enhanced and unenhanced CT was less than 4%: H&N Target Volume (TV) 2.1%, parotid 1.9%, SMG 3.6%, tongue 0.9%, spinal cord 0.3%, esophagus 2.6%, mandible 0.1% and prostate TV 0.7%, lymph node 1.1%, bladder 1.2%, rectum 1.5%, small bowel 1.2%, colon 0.6%, penile bulb 0.8%, femoral head -0.2%. The dose difference between RT plan using CM and without CM showed an increase of dose in TV. The rate of increase was less than 2.5% (3D CRT: H&N 0.69~2.51%, prostate 0.04~1.14%, IMRT: H&N 0.58~1.31%, prostate 0.36~1.04%). RT plans using a CM has the insignificant effect on the organs and TV, so this error is allowable clinically. However, the much more accurate plan is possible as to image fusion (CM and without CM images) to ROI contour and when dose calculation, use the without CM image. Using the fusion of 'ROI import' perform calculations on without CM, it will be able to reduce the error (1~3%) caused by the CM.

Characteristics of Urban Regeneration Reflected upon SymbioCity Concepts : Focused on Sweden and Germany Examples (SymbioCity관점에서 본 도시재생의 계획적 특성 고찰 : 스웨덴과 독일 사례를 중심으로)

  • Lee, Sunghee;Kim, Jongkon
    • Land and Housing Review
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    • v.8 no.4
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    • pp.275-283
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    • 2017
  • The aim of this study was to present the direction of sustainable urban regeneration through the study of planning characteristics of urban regeneration reflected upon 'SymbioCity' concepts. This study was carried out through theoretical review and case study. In the theoretical review, the theory of 'SymbioCity', one of Sweden's representative urban development models linked to the concept of sustainable development, was reviewed and the framework was derived based on this theory. The framework of this study was finally derived from 'energy', 'ecology and environment', and 'historical and cultural resources'. The case study was conducted by selecting three urban regeneration projects($V{\ddot{a}}strahamnen$ BO01, Royal seaport and HafenCity Hamburg) in Sweden and Germany. Based on the results of case analysis, the direction of sustainable urban regeneration is as follows. First, in terms of energy, we should pay attention to synergy between energy and waste and energy production. Second, in terms of ecology and environment, plans should be made to maximize the use of existing resources in order to conserve natural resources and reduce energy consumption and economic costs. Third, in terms of historical and cultural resources, it is necessary to consider ways to preserve and recycle existing buildings with historical and cultural values. Finally, for the successful application of the planning elements, it is necessary to find the most appropriate application method through steady R&D in the country or project unit.

Association of Microsatellite Marker in FABP4 Gene with Marbling Score and Live Weight in Hanwoo

  • Lee, Seung-Hwan;Cho, Yong-Min;Kim, Hyeong-Cheol;Lim, Da-Jeong;Moon, Hee-Joo;Hong, Seong-Koo;Oh, Sung-Jong;Kim, Tae-Hun;Yoon, Du-Hak;Park, Eung-Woo
    • Journal of Animal Science and Technology
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    • v.52 no.6
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    • pp.475-480
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    • 2010
  • The bovine fatty acid binding protein 4 (FABP4) plays an important role to uptake intracellular fatty acid. It has been previously reported as a positional candidate gene for marbling score in livestock. The re-sequencing of FABP4 gene detected a polymorphic AT repeated sequence in intron II of FABP4 gene. Allelic distribution for this microsatellite marker was examined in other cattle breeds. A total of 8 alleles were detected with diverse repeat units (14 to 21 AT repeat) in Hanwoo and 7 breeds. Of the 8 alleles, the predominant alleles were $[AT]_{16}$, $[AT]_{18}$ and $[AT]_{19}$ in the Hanwoo and 7 cattle breeds. The linear mixed model for genotypic effect (3237AT) on carcass traits showed a significant effect on marbling score (MAR P=0.025) and live weight (LWT; P=0.04) in the 583 Hanwoo cattle population. Live weight (LW) was highest in the homozygous $(AT)_{17}$ genotype ($557.5{\pm}6.94$) and lowest in the heterozygous $(AT)_{16/17}$ genotype ($521.7{\pm}7.70$). On the other hand, the homozygous $(AT)_{17}$ genotype ($3.0{\pm}0.15$) has the highest effect on marbling score and the lowest effect was in homozygous (AT)$_{18}$ genotype ($2.2{\pm}0.15$). The marbling score difference between both groups was 0.8 which is around two times higher than SNP genotype effect on marbling score in Limousin $\times$ Wagyu crosses.

The Effects of Government R&D Support on Private R&D Investment: Evidence from Innovative Growth Engine Policies (정부 R&D 지원이 민간 R&D 투자에 미치는 영향: 혁신성장동력 정책을 중심으로)

  • Koo, Bon-Jin;Lee, Jong-Seon
    • Asia-Pacific Journal of Business
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    • v.12 no.3
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    • pp.281-294
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    • 2021
  • Purpose - The purpose of this study was verifying the policy effects by field of innovative growth engines, focusing on the discussion of the relationship between government support and corporate R&D activities (substitute/complementary goods), and based on the results, policy recommendations for promoting private R&D were carried out. Design/methodology/approach - Through literature research, academic/theoretical discussions about relationship between government support and corporate R&D activities were synthesized. Next, survey data were collected for companies engaged in the field of innovative growth engines and empirical analysis was conducted on the relationship between government support and R&D activities in 13 major sectors. Findings - First, as a result of analyzing all companies regardless of sector, government R&D subsidies had a positive (+) relationship with R&D activities of companies engaged in innovative growth engines, that is, a complementary relationship. Next, as a result of performing empirical analysis by dividing the 13 fields, it was found that 9 fields were complementary goods in which government support had a positive (+) effect on the R&D activities of companies. On the other hand, in the remaining four fields, the effect of government support on corporate R&D activities was not statistically significant. Research implications or Originality - In order to promote R&D activities of companies in the 9 fields where government support acts as a complementary product, it is necessary to establish policies centered on direct government support. On the other hand, it would be more desirable to seek indirect support rather than direct support in the 4 fields where government support did not have a statistically significant effect on corporate R&D activities.

The Research about Map Model of 3D Road Network for Low-carbon Freight Transportation (저탄소 화물운송체계 구현을 위한 3차원 도로망도 모델에 관한 연구)

  • Lee, Sang-Hoon
    • Spatial Information Research
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    • v.20 no.4
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    • pp.29-36
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    • 2012
  • The low-carbon freight transportation system was introduced due to increase traffic congestion cost and carbon-dioxide for global climate change according to expanding city logistics demands. It is necessary to create 3D-based road network map for representing realistic road geometry with consideration of fuel consumption and carbon emissions. This study propose that 3D road network model expressed to realistic topography and road structure within trunk road for intercity freight through overlaying 2D-based transport-related thematic map and 1m-resolution DEM. The 3D-based road network map for the experimental road sections(Pyeongtaek harbor-Uiwang IC) was verified by GPS/INS survey and fuel consumption simulation. The results corresponded to effectively reflect realistic road geometry (RMSE=0.87m) except some complex structure such as overpass, and also actual fuel consumption. We expect that Green-based freight route planning and navigation system reflected on 3D geometry of complex road structure will be developed for effectively resolving energy and environmental problems.

Transition Experiment and Socially-oriented R&D Program (시스템 전환론의 관점에서 본 사회문제 해결형 연구개발사업의 발전 방향)

  • Song, Wichin;Seong, Jieun
    • Journal of Technology Innovation
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    • v.22 no.4
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    • pp.89-116
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    • 2014
  • Socially-oriented R&D programs aimed at solving societal problem rather than scientific and industrial fruits have started recently. Societal problem is recognized as dilemma since this problem related to various stakeholders. And this is not solved with single program and needed long-term process. So the perspective of socio-technical system transition including technological and institutional change is needed. This paper suggests policy implication of Socially-oriented R&D programs from socio-technical system transition perspective. 'Transitioning of Socially-oriented R&D program' is the key concept of restructuring the program for the system transition. The establishment of multi-layer transition governance and the transition vision-making and transition experiment planning are the key process of transitioning the R&D program. This paper suggests the ways and issues of implementing this process in Socially-oriented R&D program.

Status of Government Funded Projects for "Laboratory Safety" ('연구실 안전' 관련 정부연구개발사업 동향 분석)

  • Suh, Jiyoung;Kim, Hyemin;Bae, Sunyoung;Park, Jeongim
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.31 no.4
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    • pp.396-416
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    • 2021
  • Objectives: This study was conducted to analyze the trends of government R&D (R&D) projects related to laboratory safety over the past 20 years. Methods: We collected publications from various databases(DBs) with words such as laboratory(ies), lab(s), researcher(s), laboratory worker(s), safety, environment, hazard(s), risk(s), and so on. Selected publications were analyzed by the research funds and the number of projects according to the investment subject and research characteristics. Results: About 93% of the total R&D budget went to government policy projects, not scientific research. Second, from the perspective of 'safety management activities', most of the research is related to management and inspection at the organizational level. Issues that need to be discussed at the national level like policy governance are not included. Third, focusing on the 'safety management cycle', there were few studies related to 'prediction' or 'post-response'. Fourth, when an analysis framework combining the perspectives of 'safety management activities' and 'safety management cycle' is applied, most of the budget is spent on infrastructure such as digital management systems, whereas basic knowledge for prevention and production of evidence was very few. Conclusions: In order to prevent policy planning without policy evaluation, implementation without strategy, and evaluation without evidence, it is necessary to expand investment in empirical research on risks, research on the effectiveness of current application methods, and research on theory development. The government budget for laboratory safety-related projects should be managed separately from the R&D budget for scientific research. Although less than 5% of the budget allocated to scientific research is the total budget, an optical illusion occurs because both the project budget and the scientific research budget are counted as R&D budgets.

The Evaluation on the Noise Environment of the Low-rise Multi-family house in Athens,U,S,A (미국 Athens 지역 저층 공동주택 소음 환경평가에 관한 연구)

  • 곽경숙
    • Journal of the Korean housing association
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    • v.11 no.4
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    • pp.85-96
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    • 2000
  • The purpose of this study was to evaluated noise environment of the low-rise multi-family house in Athens, Georgia. The results of this study can be applied to the prevention of noise when planning multi-family houses, roads and cities in Korea. The subjects of this study were the place of 1m, 10m, 50m, 100m from 4-lane road ofT apartment and 233 residents lived in the low-rise multi-family houses in Athens. The results of this study were as follows. 1. The average noise level at 1m, 10m, 50m and 100m was 55.5dB, 46.7dB, 43.0dB, 43.0dB and 41.2dB respectively from 4-lane road of T apartment. From the view of the standard in this study, the physical noise was good. 2. The results of the residents subjective response on the noise were as follows. The external noise residents felt - that was a noise by operating machines, and traffic noise - ware as 2.57 on average. The noise by the daily activities, the noise of nature are a little as 2.38 on average. They were disturbed a little by the external noise. They felt the solid born sounds(average 2.49) more than airbone sound(average 2.23) by the internal noise. They are suffered worse from noise in summer and they worse from 8-12 oclock due to external noise and 16-20 oclock due to internal noise. Comparing the noise environment of Korean with that of American, I found a meaningful difference of nature and the noise of daily activities of external noise and all internal noise.

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FEED RESOURCE AVAILABILITY AND UTILIZATION IN SMALLHOLDER PIG FARMS IN SRI LANKA

  • Ravindran, V.;Cyril, H.W.;Nadesalingam, P.;Gunawardene, D.D.
    • Asian-Australasian Journal of Animal Sciences
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    • v.8 no.4
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    • pp.311-316
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    • 1995
  • Data on available feed resources, feeding practices and nutrient adequacy of rations under small farm conditions in Sri Lanka were obtained in a baseline survey involving 104 pig farms. The results showed that a wide range of non-conventional feedstuffs are used for pig feeding under typical small farm conditions and that dietary protein quality is a major factor limiting productivity. Following the survey, two on-farm trials were conducted to evaluate cheaper, alternative feeding strategies. In trial 1, a test diet was formulated using several non-conventional feedstuffs and compared with a commercial feed that is normally fed in the farms. In trial 2, the possibility of improving growth rates by amino acid supplementation was evaluated. The results demonstrated that feed costs can be considerably lowered through these packages. Some problems inherent to on-farm livestock trials are highlighted.

Effect of internal and external capabilities and activities of a company on absorptive capacity and performance (기업의 내부 및 외부역량과 활동이 흡수역량과 성과에 미치는 영향)

  • Kim, Young-Ki;Park, Seong-Taek
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.125-136
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    • 2021
  • Innovation is essential for the survival of a company in the fierce competitive environment of the global era of borders along with rapid technological development and changes from the environment. It is very important to secure your own competitive advantage. In this study, the relationship between internal R&D capability and organizational support as a company internal factor and external R&D capability, external knowledge search, and absorptive capability as a company external factor on performance was examined. As a result of the analysis, it was found that internal R&D capability, organizational support, and external knowledge search had a significant effect on absorptive capability, and innovation performance had a positive effect on new product performance. However, the mediating effect of absorptive capacity has not been verified, suggesting that absorptive capacity has a low correlation between innovation performance and new product performance, or that other important factors act between absorptive capacity and performance variables. The results of this study are expected to be utilized as useful guidelines when establishing R&D strategies in companies.